Experiment set4H5 for Marinobacter adhaerens HP15

Compare to:

marine broth with Cholin acetate 153.15 mM

200 most detrimental genes:

  gene name fitness t score description  
HP15_2442 +4.3 25.7 RNA polymerase, sigma 54 subunit, RpoN compare
HP15_2470 +3.9 20.0 metal ion transporter compare
HP15_p42g17 +3.9 17.0 traN-like protein compare
HP15_755 +3.9 21.3 Mg2+ and Co2+ transporter CorB compare
HP15_3054 +3.5 22.2 TPR repeat containing protein compare
HP15_351 +3.3 27.8 Cl-channel, voltage-gated family protein compare
HP15_2451 +3.3 14.8 ribonuclease, Rne/Rng family compare
HP15_228 +3.0 21.8 guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase compare
HP15_p42g15 +2.9 10.8 KfrA protein compare
HP15_432 +2.8 13.8 outer membrane protein (porin) compare
HP15_3820 +2.7 18.1 major facilitator superfamily MFS_1 conserved
HP15_260 +2.6 4.6 hydrolase, alpha/beta fold family protein compare
HP15_2424 +2.5 3.5 AFG1-family ATPase compare
HP15_1130 +2.5 17.7 transporter, BCCT family protein compare
HP15_1175 +2.3 4.1 outer membrane chaperone Skp (OmpH) compare
HP15_p42g16 +2.3 3.9 conjugal transfer protein TraO compare
HP15_3907 +2.3 16.1 sodium/alanine symporter family protein compare
HP15_1805 +2.3 10.9 hydroxyacylglutathione hydrolase compare
HP15_3211 +2.3 6.3 5-formyltetrahydrofolate cyclo-ligase compare
HP15_791 +2.2 14.7 (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA compare
HP15_3278 +2.2 10.6 dimethyladenosine transferase compare
HP15_1467 +2.2 1.5 fFlagellar basal-body rod protein FlgB compare
HP15_3277 +2.2 5.8 diadenosine tetraphosphatase compare
HP15_3344 +2.1 13.4 phosphate transporter family protein compare
HP15_1295 +2.1 8.6 protein containing DUF416 compare
HP15_2166 +2.0 12.3 glycerol kinase compare
HP15_2417 +2.0 2.6 YfaZ family protein compare
HP15_3534 +2.0 1.8 conserved hypothetical protein, membrane compare
HP15_462 +2.0 7.1 dinucleoside polyphosphate hydrolase compare
HP15_1806 +1.8 2.2 membrane-bound lytic murein transglycosylase D precursor compare
HP15_1733 +1.8 3.5 conserved hypothetical protein compare
HP15_2048 +1.8 5.2 UDP-glucose 4-epimerase compare
HP15_2176 +1.7 7.0 pyruvate kinase II compare
HP15_273 +1.7 6.3 spermidine synthase compare
HP15_2297 +1.7 5.7 response regulator receiver modulated CheB methylesterase compare
HP15_1037 +1.6 5.2 two-component response regulator compare
HP15_3603 +1.6 10.8 transcriptional regulator, HxlR family compare
HP15_435 +1.6 8.0 glutamate-ammonia-ligase adenylyltransferase compare
HP15_2781 +1.6 2.3 hypothetical protein compare
HP15_555 +1.5 2.9 MraZ protein compare
HP15_1187 +1.5 2.1 BolA-like protein compare
HP15_2336 +1.5 4.1 LexA repressor compare
HP15_3038 +1.5 7.5 N-succinylarginine dihydrolase compare
HP15_329 +1.5 5.9 two-component sensor compare
HP15_1318 +1.5 4.9 RDD domain containing protein compare
HP15_578 +1.5 5.3 molybdenum cofactor biosynthesis protein C compare
HP15_328 +1.4 1.6 two component, sigma54 specific, transcriptional regulator, Fis family compare
HP15_3781 +1.4 6.5 electron transport protein SCO1/SenC compare
HP15_1409 +1.4 1.4 protein containing DUF1289 compare
HP15_704 +1.4 2.7 translation-associated GTPase compare
HP15_779 +1.3 4.3 serine protease MucD precursor compare
HP15_2111 +1.3 2.2 iron-sulfur cluster-binding protein compare
HP15_2502 +1.3 2.0 N-acetylmuramoyl-L-alanine amidase-like protein compare
HP15_3201 +1.3 7.5 ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family compare
HP15_2101 +1.3 5.4 membrane protein containing cytochrome c assembly protein, transmembrane region domain compare
HP15_272 +1.3 7.7 biosynthetic arginine decarboxylase compare
HP15_1725 +1.2 4.7 conserved hypothetical protein compare
HP15_598 +1.2 7.7 phosphoesterase, PA-phosphatase compare
HP15_446 +1.2 7.9 glycosyltransferase compare
HP15_213 +1.2 2.6 cytochrome c5 compare
HP15_2469 +1.2 1.9 predicted metal-dependent hydrolase compare
HP15_3512 +1.2 5.8 glutathione synthetase compare
HP15_652 +1.2 1.8 conserved hypothetical protein compare
HP15_1829 +1.1 3.0 tRNA pseudouridine synthase A compare
HP15_1301 +1.1 2.4 phosphatidylglycerophosphate synthase compare
HP15_261 +1.1 1.2 hypothetical protein compare
HP15_1530 +1.1 3.8 RNA-binding S4 domain protein compare
HP15_1063 +1.1 1.1 protein containing DUF1315 compare
HP15_330 +1.1 5.0 conserved hypothetical protein, membrane compare
HP15_724 +1.1 6.9 periplasmic sensor signal transduction histidine kinase compare
HP15_1605 +1.1 2.1 general secretion pathway protein H compare
HP15_137 +1.1 0.8 hypothetical protein compare
HP15_975 +1.1 1.4 hypothetical protein compare
HP15_2906 +1.1 1.2 conserved hypothetical protein compare
HP15_255 +1.1 4.7 conserved hypothetical protein compare
HP15_514 +1.0 1.0 peptidylprolyl isomerase, FKBP-type compare
HP15_2700 +1.0 1.9 phenylacetate-CoA oxygenase, PaaJ subunit compare
HP15_3210 +1.0 1.6 cell division protein ZapA-like protein compare
HP15_2100 +1.0 2.3 transporting ATPase compare
HP15_2295 +1.0 4.1 flagellar motor protein MotD compare
HP15_2288 +1.0 1.6 flagellar protein FhlB cytoplasmic domain protein compare
HP15_3100 +1.0 0.9 hypothetical protein compare
HP15_3055 +1.0 5.8 high-affinity leucine-specific leucine-specific-binding periplasmic protein of high-affinity branched-chain amino acid ABC transporter transport system periplasmic binding protein compare
HP15_1625 +1.0 2.9 3-oxoacyl-(acyl carrier protein) synthase III compare
HP15_2452 +1.0 2.5 Maf-like protein compare
HP15_24 +1.0 3.8 membrane protein compare
HP15_908 +1.0 1.4 enoyl-CoA hydratase/isomerase compare
HP15_1931 +1.0 3.6 2-methylcitrate synthase/citrate synthase II compare
HP15_2026 +1.0 1.4 lipoprotein compare
HP15_tRNA50 +1.0 1.9 tRNA-Pro compare
HP15_987 +1.0 4.3 conserved hypothetical protein compare
HP15_3951 +1.0 7.3 signal-transduction protein compare
HP15_447 +1.0 4.4 glycosyltransferase compare
HP15_1177 +1.0 1.0 (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase compare
HP15_1311 +1.0 3.0 ATP-cobalamin adenosyltransferase compare
HP15_3040 +0.9 5.1 Arginine N-succinyltransferase (EC 2.3.1.109) (from data) compare
HP15_2183 +0.9 5.1 DNA-binding ATP-dependent protease La compare
HP15_2833 +0.9 2.2 conserved hypothetical protein compare
HP15_4128 +0.9 5.4 molybdopterin biosynthesis protein MoeA-like protein compare
HP15_3948 +0.9 6.9 periplasmic sensor signal transduction histidine kinase compare
HP15_3108 +0.9 0.9 hypothetical protein compare
HP15_3847 +0.9 1.7 transmembrane transcriptional regulator (anti-Sigma-factor) compare
HP15_2296 +0.9 2.6 chemotaxis protein MotA compare
HP15_127 +0.9 1.2 hypothetical protein compare
HP15_1839 +0.9 2.7 protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific compare
HP15_472 +0.9 3.3 malate dehydrogenase (oxaloacetate-decarboxylating), NADP(+) compare
HP15_636 +0.9 3.1 GTP-binding protein, ribosome biogenesis, YlqF compare
HP15_1101 +0.9 3.3 transposase IS3/IS911 compare
HP15_2300 +0.9 3.7 chemotaxis phosphatase, CheZ compare
HP15_577 +0.9 1.2 mutator MutT protein compare
HP15_251 +0.9 5.5 diguanylate cyclase compare
HP15_1236 +0.9 6.5 conserved hypothetical protein compare
HP15_2697 +0.9 3.1 phenylacetate-CoA oxygenase, PaaG subunit compare
HP15_2073 +0.9 3.6 peptidyl-arginine deiminase family protein compare
HP15_1734 +0.9 1.9 ABC-type multidrug transport system, ATPase component compare
HP15_770 +0.9 2.4 signal transduction protein compare
HP15_420 +0.9 1.7 type II secretory pathway, pseudopilin PulG compare
HP15_2360 +0.9 1.6 FxsA cytoplasmic membrane protein compare
HP15_257 +0.9 3.7 transcriptional regulator, GntR family compare
HP15_710 +0.8 3.1 tetratricopeptide TPR_2 repeat protein compare
HP15_3088 +0.8 2.5 oligoketide cyclase/lipid transport protein compare
HP15_3359 +0.8 3.5 pseudouridine synthase, Rsu compare
HP15_256 +0.8 4.0 serine protease compare
HP15_3771 +0.8 4.4 membrane protein containing cytochrome c oxidase, subunit II domain compare
HP15_588 +0.8 4.7 DEAD/DEAH box helicase domain protein compare
HP15_635 +0.8 4.6 3-oxoacyl-(acyl carrier protein) synthase I compare
HP15_917 +0.8 2.6 hypothetical protein compare
HP15_2167 +0.8 2.4 transcriptional repressor for the dissimilation of sn-glycerol 3-phosphate, DeoR family protein compare
HP15_3121 +0.8 4.3 malate:quinone oxidoreductase compare
HP15_2277 +0.8 1.3 TPR repeat protein compare
HP15_3212 +0.8 1.8 secreted protein compare
HP15_p187g144 +0.8 2.0 hypothetical protein compare
HP15_431 +0.8 3.8 D-tyrosyl-tRNA(Tyr) deacylase compare
HP15_603 +0.8 1.7 Iojap-related protein compare
HP15_1727 +0.8 2.6 glycosyltransferase compare
HP15_946 +0.8 3.0 conserved hypothetical protein compare
HP15_1283 +0.8 5.1 RNA polymerase, sigma 70 subunit, RpoD family compare
HP15_4011 +0.8 3.6 protein containing DUF1232 compare
HP15_3037 +0.8 3.9 transcriptional regulator, TetR family protein compare
HP15_2661 +0.8 1.3 Citrate uptake transporter, substrate-binding component TctC (from data) compare
HP15_1173 +0.8 2.5 membrane-associated zinc metalloprotease compare
HP15_2298 +0.8 4.9 chemotaxis histidine kinase compare
HP15_2230 +0.8 2.5 phosphotransferase YdiA compare
HP15_1902 +0.8 2.8 glucose-1-phosphate cytidylyltransferase compare
HP15_961 +0.8 1.7 hypothetical protein compare
HP15_3813 +0.8 4.4 conserved hypothetical protein compare
HP15_811 +0.8 3.4 acetyl-CoA synthetase compare
HP15_725 +0.8 4.6 two component, sigma54 specific, transcriptional regulator, Fis family compare
HP15_2225 +0.8 2.5 YciI-like protein compare
HP15_p42g14 +0.8 1.8 hypothetical protein compare
HP15_722 +0.8 4.9 TRAP transporter for fumarate, succinate, L-malate, and 2-oxoglutarate, solute receptor component (from data) compare
HP15_2684 +0.8 5.1 TRAP-type C4-dicarboxylate transport system, large permease component compare
HP15_4030 +0.8 0.9 chloroplast-type ferredoxin compare
HP15_2972 +0.8 0.8 cyclic nucleotide-binding protein compare
HP15_1501 +0.8 1.0 hypothetical protein compare
HP15_2459 +0.8 3.5 MiaB-like tRNA modifying enzyme YliG compare
HP15_249 +0.8 1.6 protein containing DUF484 compare
HP15_3456 +0.8 0.7 protein containing DUF465 compare
HP15_3056 +0.8 2.2 high-affinity branched-chain amino acid ABC transporter, permease protein compare
HP15_649 +0.8 1.3 phage tail protein X compare
HP15_1737 +0.7 3.6 enoyl-CoA hydratase/isomerase compare
HP15_296 +0.7 2.3 conserved hypothetical protein compare
HP15_2867 +0.7 1.9 HypX compare
HP15_254 +0.7 3.0 conserved hypothetical protein compare
HP15_655 +0.7 2.2 phage tail collar domain protein-like protein compare
HP15_2419 +0.7 3.6 bax protein compare
HP15_1864 +0.7 3.7 acyl-CoA synthase compare
HP15_3629 +0.7 3.6 conserved hypothetical protein compare
HP15_614 +0.7 2.0 protein containing glutaredoxin domain compare
HP15_2008 +0.7 1.0 conserved hypothetical protein compare
HP15_4057 +0.7 1.7 protein containing rhodanese-like domains compare
HP15_466 +0.7 3.0 ATP-dependent protease peptidase subunit compare
HP15_3759 +0.7 5.2 oligopeptidase A-like protein compare
HP15_2267 +0.7 0.8 hypothetical protein compare
HP15_871 +0.7 1.1 NLP/P60 family protein compare
HP15_1038 +0.7 3.3 sensory box histidine kinase compare
HP15_2701 +0.7 1.1 phenylacetic acid degradation oxidoreductase PaaK compare
HP15_227 +0.7 1.7 hypothetical protein compare
HP15_232 +0.7 4.1 molybdenum cofactor synthesis domain protein compare
HP15_2695 +0.7 4.1 Beta-ketoadipyl CoA thiolase (EC 2.3.1.-) (from data) compare
HP15_1568 +0.7 2.6 excinuclease ABC subunit C compare
HP15_616 +0.7 4.1 UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase compare
HP15_2160 +0.7 1.9 transmembrane protein compare
HP15_3057 +0.7 4.0 leucine/isoleucine/valine transporter permease subunit compare
HP15_723 +0.7 4.7 TRAP transporter for fumarate, succinate, L-malate, and 2-oxoglutarate, fused 4TM/12TM components (from data) compare
HP15_1193 +0.7 1.4 conserved hypothetical protein compare
HP15_1225 +0.7 1.8 oxidoreductase, short chain dehydrogenase/reductase family compare
HP15_230 +0.7 3.5 molybdenum cofactor biosynthesis protein E compare
HP15_2660 +0.7 1.3 Citrate uptake transporter, small transmembrane component TctB (from data) compare
HP15_2099 +0.7 3.8 DEAD/DEAH box helicase domain protein compare
HP15_1221 +0.7 2.2 recombination-associated protein rdgC compare
HP15_899 +0.7 2.5 protein YeeN compare
HP15_2077 +0.7 2.7 leucyl/phenylalanyl-tRNA-protein transferase compare
HP15_2862 +0.7 1.7 conserved hypothetical protein compare
HP15_3041 +0.7 3.8 Arginine N-succinyltransferase (EC 2.3.1.109) (from data) compare
HP15_1282 +0.7 2.9 peptidase M23B compare
HP15_4127 +0.7 1.5 conserved hypothetical protein compare
HP15_1985 +0.7 2.2 protein containing phage antirepressor protein domain compare
HP15_156 +0.7 1.1 conserved hypothetical protein compare
HP15_658 +0.7 4.9 secreted protein-putative xanthan lyase compare


Specific Phenotypes

For 24 genes in this experiment

For stress Cholin acetate in Marinobacter adhaerens HP15

For stress Cholin acetate across organisms