Experiment set4H48 for Pseudomonas stutzeri RCH2

Compare to:

LB with Polymyxin B sulfate 0.0001 mg/ml

200 most important genes:

  gene name fitness t score description  
Psest_0993 -6.8 -11.3 Glucose-6-phosphate isomerase compare
Psest_2232 -6.1 -16.2 UTP-glucose-1-phosphate uridylyltransferase compare
Psest_0457 -6.0 -3.6 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_0498 -5.1 -1.8 ribosome small subunit-dependent GTPase A compare
Psest_2712 -5.0 -8.2 Surface lipoprotein compare
Psest_3303 -4.8 -5.7 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_3031 -4.8 -1.0 hypothetical protein compare
Psest_3850 -4.7 -1.0 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_3306 -4.7 -5.4 conserved hypothetical integral membrane protein compare
Psest_3305 -4.7 -7.8 ABC-type transport system involved in resistance to organic solvents, periplasmic component compare
Psest_1505 -4.7 -2.2 Organic radical activating enzymes compare
Psest_0309 -4.6 -1.7 RND family efflux transporter, MFP subunit compare
Psest_0062 -4.6 -3.2 tryptophan synthase, alpha subunit compare
Psest_3304 -4.3 -6.6 ABC-type transport system involved in resistance to organic solvents, auxiliary component compare
Psest_4078 -4.1 -2.1 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D compare
Psest_3531 -4.1 -1.5 Peptidase propeptide and YPEB domain. compare
Psest_1496 -3.9 -1.4 Holliday junction DNA helicase, RuvA subunit compare
Psest_3228 -3.9 -13.8 Zn-dependent protease with chaperone function compare
Psest_1660 -3.8 -3.4 NADH:ubiquinone oxidoreductase, Na(+)-translocating, F subunit compare
Psest_2714 -3.8 -2.1 7-cyano-7-deazaguanine reductase compare
Psest_3338 -3.8 -1.5 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain compare
Psest_2316 -3.8 -13.1 phosphoenolpyruvate synthase compare
Psest_2945 -3.7 -2.6 septum site-determining protein MinC compare
Psest_3307 -3.7 -8.8 ABC-type transport system involved in resistance to organic solvents, ATPase component compare
Psest_2584 -3.6 -8.5 Phosphoribosylanthranilate isomerase compare
Psest_3145 -3.5 -1.7 hypothetical protein compare
Psest_4274 -3.4 -4.7 hypothetical protein compare
Psest_0063 -3.3 -3.9 tryptophan synthase, beta subunit compare
Psest_2613 -3.1 -1.8 hypothetical protein compare
Psest_3883 -3.1 -5.0 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_0310 -3.0 -3.5 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family compare
Psest_2304 -2.9 -1.7 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family compare
Psest_1814 -2.9 -18.3 pseudaminic acid biosynthesis N-acetyl transferase compare
Psest_1472 -2.9 -6.5 Protein of unknown function (DUF3108). compare
Psest_3647 -2.9 -8.5 Indole-3-glycerol phosphate synthase compare
Psest_0114 -2.8 -1.4 RNA polymerase sigma factor, sigma-70 family compare
Psest_2946 -2.8 -4.7 septum site-determining protein MinD compare
Psest_0466 -2.8 -4.1 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_1540 -2.8 -1.5 biotin-dependent carboxylase uncharacterized domain compare
Psest_3810 -2.8 -3.6 orotate phosphoribosyltransferase compare
Psest_1824 -2.8 -4.4 Sugar transferases involved in lipopolysaccharide synthesis compare
Psest_1752 -2.7 -1.7 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB compare
Psest_1491 -2.6 -4.0 Cold shock proteins compare
Psest_1417 -2.6 -0.7 hypothetical protein compare
Psest_3092 -2.5 -1.3 ribonuclease III, bacterial compare
Psest_0558 -2.5 -0.9 urease, beta subunit compare
Psest_2333 -2.5 -1.1 Protein of unknown function (DUF3359). compare
Psest_0662 -2.5 -1.7 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_3002 -2.4 -1.2 Putative translation initiation inhibitor, yjgF family compare
Psest_3697 -2.4 -1.2 Outer membrane lipoprotein carrier protein LolA. compare
Psest_0259 -2.4 -1.3 cell division ATP-binding protein FtsE compare
Psest_4243 -2.4 -1.2 type VI secretion lipoprotein, VC_A0113 family compare
Psest_3862 -2.4 -10.7 phosphoenolpyruvate-protein phosphotransferase compare
Psest_2334 -2.4 -10.9 Uncharacterized protein conserved in bacteria compare
Psest_1813 -2.4 -8.4 pseudaminic acid biosynthesis-associated protein PseG compare
Psest_3322 -2.4 -14.4 TIGR02099 family protein compare
Psest_3648 -2.4 -7.3 anthranilate phosphoribosyltransferase compare
Psest_0181 -2.4 -5.8 glycine cleavage system T protein compare
Psest_3766 -2.4 -2.2 Uncharacterized protein conserved in bacteria compare
Psest_3767 -2.3 -5.0 tyrosine recombinase XerC compare
Psest_4406 -2.3 -1.8 hypothetical protein compare
Psest_0998 -2.3 -3.5 poly(A) polymerase compare
Psest_0186 -2.3 -4.3 Protein-disulfide isomerase compare
Psest_3317 -2.3 -3.3 Phosphotransferase System HPr (HPr) Family compare
Psest_1975 -2.3 -7.8 Predicted transcriptional regulators compare
Psest_1122 -2.3 -11.2 putative adhesin (DUF1302) (from data) compare
Psest_0958 -2.3 -10.8 Oligoketide cyclase/lipid transport protein compare
Psest_1837 -2.3 -5.5 Endoglucanase compare
Psest_3476 -2.3 -0.7 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_2651 -2.2 -3.9 DNA topoisomerase I, bacterial compare
Psest_1809 -2.2 -7.9 Membrane protein involved in the export of O-antigen and teichoic acid compare
Psest_0164 -2.2 -1.0 Glutaredoxin, GrxC family compare
Psest_3927 -2.2 -3.5 thiazole biosynthesis/tRNA modification protein ThiI compare
Psest_1819 -2.2 -12.2 Nucleoside-diphosphate-sugar epimerases compare
Psest_2794 -2.2 -3.2 Predicted permease, DMT superfamily compare
Psest_0485 -2.2 -3.5 clan AA aspartic protease, TIGR02281 family compare
Psest_3456 -2.2 -0.7 RNA polymerase sigma factor, sigma-70 family compare
Psest_1506 -2.1 -5.1 queuosine biosynthesis protein QueC compare
Psest_0455 -2.1 -4.5 ADP-heptose:LPS heptosyltransferase compare
Psest_0464 -2.1 -9.9 Mannosyltransferase OCH1 and related enzymes compare
Psest_4343 -2.1 -1.3 Protein of unknown function (DUF3301). compare
Psest_0461 -2.0 -3.6 Glycosyltransferase involved in LPS biosynthesis compare
Psest_3064 -2.0 -2.0 hypothetical protein compare
Psest_0515 -2.0 -5.1 rare lipoprotein A compare
Psest_2325 -2.0 -5.6 alpha-L-glutamate ligase-related protein compare
Psest_1215 -2.0 -1.9 Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) compare
Psest_0737 -2.0 -0.4 Cu(I)-responsive transcriptional regulator compare
Psest_3990 -1.9 -4.6 PAP2 superfamily. compare
Psest_1486 -1.9 -2.1 hypothetical protein compare
Psest_0516 -1.9 -7.8 D-alanyl-D-alanine carboxypeptidase compare
Psest_0542 -1.9 -6.7 AMP nucleosidase compare
Psest_3784 -1.9 -1.7 glyceraldehyde-3-phosphate dehydrogenase, type I compare
Psest_1056 -1.9 -1.4 2-isopropylmalate synthase, bacterial type compare
Psest_2557 -1.9 -1.9 Protein of unknown function (DUF2474). compare
Psest_1661 -1.9 -3.1 Membrane-associated lipoprotein involved in thiamine biosynthesis compare
Psest_1510 -1.9 -2.8 Putative Zn-dependent protease, contains TPR repeats compare
Psest_4393 -1.9 -5.0 Capsule polysaccharide export protein compare
Psest_1663 -1.9 -2.8 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes compare
Psest_3884 -1.9 -0.4 Signal transduction histidine kinase compare
Psest_1143 -1.8 -3.9 Small-conductance mechanosensitive channel compare
Psest_0355 -1.8 -1.7 Glycine cleavage system regulatory protein compare
Psest_1709 -1.8 -2.9 Outer membrane protein and related peptidoglycan-associated (lipo)proteins compare
Psest_1601 -1.8 -1.1 Signal transduction histidine kinase compare
Psest_0402 -1.8 -1.7 glycosyltransferase, MGT family compare
Psest_1241 -1.8 -5.2 S-adenosylmethionine:tRNA ribosyltransferase-isomerase compare
Psest_4335 -1.8 -3.0 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems compare
Psest_2585 -1.8 -1.0 pseudouridylate synthase I compare
Psest_1631 -1.8 -1.0 Uncharacterized conserved small protein compare
Psest_3339 -1.7 -4.7 Signal transduction histidine kinase compare
Psest_0028 -1.7 -2.6 Coproporphyrinogen III oxidase compare
Psest_4044 -1.7 -5.7 type I site-specific deoxyribonuclease, HsdR family compare
Psest_0311 -1.7 -3.8 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family compare
Psest_1997 -1.7 -1.1 6-phosphogluconolactonase compare
Psest_4219 -1.6 -1.1 DNA polymerase I compare
Psest_2011 -1.6 -4.5 Predicted permease compare
Psest_2017 -1.6 -3.4 Predicted acyltransferase compare
Psest_3908 -1.6 -0.5 Cytochrome c553 compare
Psest_1489 -1.6 -2.9 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases compare
Psest_1008 -1.6 -1.0 hypothetical protein compare
Psest_2037 -1.6 -4.0 uroporphyrin-III C-methyltransferase compare
Psest_0575 -1.6 -0.7 HrpA-like helicases compare
Psest_1162 -1.6 -1.5 Spermidine synthase compare
Psest_3650 -1.6 -7.9 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_1750 -1.6 -2.3 Protein of unknown function (DUF2802). compare
Psest_1318 -1.6 -2.4 ABC-type phosphate/phosphonate transport system, permease component compare
Psest_1812 -1.5 -4.6 pseudaminic acid CMP-transferase compare
Psest_4220 -1.5 -2.2 Protein of unknown function (DUF2782). compare
Psest_0152 -1.5 -4.6 Imidazoleglycerol-phosphate dehydratase compare
Psest_1053 -1.5 -1.0 hypothetical protein compare
Psest_2260 -1.5 -8.0 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_2872 -1.5 -1.3 protein RecA compare
Psest_4310 -1.5 -0.9 ABC-type Mn2+/Zn2+ transport systems, permease components compare
Psest_0846 -1.5 -1.6 Uncharacterized protein probably involved in high-affinity Fe2+ transport compare
Psest_0708 -1.5 -1.3 outer membrane assembly lipoprotein YfiO compare
Psest_3962 -1.5 -0.8 haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED compare
Psest_2025 -1.5 -1.0 cold shock domain protein CspD compare
Psest_1602 -1.5 -1.2 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_0842 -1.5 -1.2 anaerobic ribonucleoside-triphosphate reductase activating protein compare
Psest_3085 -1.5 -6.0 methyltransferase, putative compare
Psest_1843 -1.5 -1.5 Uncharacterized Fe-S protein compare
Psest_1885 -1.5 -3.0 hypothetical protein compare
Psest_2324 -1.5 -7.7 hypothetical protein compare
Psest_2001 -1.5 -2.1 2-phosphoglycolate phosphatase, prokaryotic compare
Psest_4170 -1.5 -0.9 Flagellar biosynthesis/type III secretory pathway protein compare
Psest_1860 -1.4 -2.3 Uncharacterized conserved protein compare
Psest_1679 -1.4 -1.2 ribonuclease, Rne/Rng family compare
Psest_2096 -1.4 -1.9 Domain of unknown function (DUF1883). compare
Psest_1920 -1.4 -0.8 Uncharacterized protein conserved in bacteria compare
Psest_0471 -1.4 -5.2 hypothetical protein compare
Psest_0212 -1.4 -0.7 exodeoxyribonuclease V, gamma subunit compare
Psest_1651 -1.4 -3.2 Superfamily II DNA/RNA helicases, SNF2 family compare
Psest_1871 -1.4 -4.2 Predicted esterase of the alpha-beta hydrolase superfamily compare
Psest_2344 -1.4 -1.6 Methyl-accepting chemotaxis protein compare
Psest_0805 -1.4 -1.8 hypothetical protein compare
Psest_2517 -1.4 -2.5 hypothetical protein compare
Psest_3151 -1.4 -2.3 hypothetical protein compare
Psest_4203 -1.4 -3.3 NAD/NADP transhydrogenase alpha subunit compare
Psest_1796 -1.4 -1.9 Predicted NAD/FAD-dependent oxidoreductase compare
Psest_1822 -1.4 -4.0 Glycosyltransferases involved in cell wall biogenesis compare
Psest_3524 -1.4 -5.0 ribose-phosphate pyrophosphokinase compare
Psest_3775 -1.4 -3.1 Mg chelatase-related protein compare
Psest_0969 -1.4 -1.4 transcription elongation factor GreA compare
Psest_0133 -1.4 -1.0 type VI secretion protein, VC_A0107 family compare
Psest_1292 -1.3 -6.0 monothiol glutaredoxin, Grx4 family compare
Psest_2229 -1.3 -2.1 Uncharacterized protein conserved in bacteria compare
Psest_0225 -1.3 -0.9 Predicted permease, DMT superfamily compare
Psest_0844 -1.3 -3.0 High-affinity Fe2+/Pb2+ permease compare
Psest_0678 -1.3 -1.4 yjeF C-terminal region, hydroxyethylthiazole kinase-related/yjeF N-terminal region compare
Psest_0533 -1.3 -3.5 Sel1 repeat. compare
Psest_4315 -1.3 -1.6 ABC-type metal ion transport system, permease component compare
Psest_0501 -1.3 -1.8 Predicted nucleoside-diphosphate-sugar epimerases compare
Psest_3222 -1.3 -1.7 Putative threonine efflux protein compare
Psest_1625 -1.3 -2.7 hypothetical protein compare
Psest_2323 -1.3 -5.9 Uncharacterized protein conserved in archaea compare
Psest_0073 -1.3 -2.6 ABC-type multidrug transport system, ATPase and permease components compare
Psest_1049 -1.3 -1.8 Uncharacterized paraquat-inducible protein A compare
Psest_0148 -1.3 -4.3 nitrate transport ATP-binding subunits C and D compare
Psest_4371 -1.3 -1.6 Multisubunit Na+/H+ antiporter, MnhB subunit compare
Psest_2322 -1.3 -2.9 Transcriptional regulators compare
Psest_3860 -1.3 -2.1 Predicted permeases compare
Psest_0113 -1.3 -1.8 Uncharacterized protein conserved in bacteria compare
Psest_0476 -1.3 -4.1 type I secretion outer membrane protein, TolC family compare
Psest_0359 -1.3 -1.6 Transcriptional regulators compare
Psest_1560 -1.3 -2.9 hypothetical protein compare
Psest_3301 -1.2 -2.1 Predicted transcriptional regulator, BolA superfamily compare
Psest_4021 -1.2 -2.7 hypothetical protein compare
Psest_1522 -1.2 -1.6 hypothetical protein compare
Psest_2561 -1.2 -0.9 hypothetical protein compare
Psest_0209 -1.2 -0.5 membrane protein AbrB duplication compare
Psest_2150 -1.2 -1.5 DNA polymerase LigD, polymerase domain compare
Psest_4172 -1.2 -2.9 flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF) compare
Psest_0749 -1.2 -3.4 Transcriptional regulator compare
Psest_4318 -1.2 -3.8 Predicted dioxygenase of extradiol dioxygenase family compare
Psest_1325 -1.2 -2.8 Molecular chaperone compare
Psest_3732 -1.2 -3.0 polyphosphate kinase 1 compare
Psest_3562 -1.2 -1.2 ABC-type antimicrobial peptide transport system, ATPase component compare
Psest_3351 -1.2 -4.5 peptide chain release factor 3 compare
Psest_0175 -1.2 -4.8 Xaa-Pro aminopeptidase compare
Psest_2332 -1.2 -5.3 Predicted acetyltransferase compare
Psest_1391 -1.2 -3.6 ABC-type uncharacterized transport system, permease component compare


Specific Phenotypes

For 11 genes in this experiment

For stress Polymyxin B sulfate in Pseudomonas stutzeri RCH2

For stress Polymyxin B sulfate across organisms