Experiment set4H35 for Pseudomonas stutzeri RCH2

Compare to:

LB with 5-Hydroxymethylfurfural 5 mM

200 most detrimental genes:

  gene name fitness t score description  
Psest_1215 +1.5 2.8 Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) compare
Psest_3670 +1.4 11.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
Psest_3573 +1.2 4.2 dTDP-4-dehydrorhamnose reductase compare
Psest_3002 +1.1 1.8 Putative translation initiation inhibitor, yjgF family compare
Psest_3146 +1.1 2.8 hypothetical protein compare
Psest_0097 +1.0 1.3 phosphonates metabolism transcriptional regulator PhnF compare
Psest_3905 +1.0 2.8 formate dehydrogenase, alpha subunit, archaeal-type compare
Psest_3031 +0.9 1.5 hypothetical protein compare
Psest_2333 +0.9 1.8 Protein of unknown function (DUF3359). compare
Psest_1679 +0.9 2.5 ribonuclease, Rne/Rng family compare
Psest_4298 +0.9 0.7 Response regulator containing a CheY-like receiver domain and a GGDEF domain compare
Psest_4043 +0.9 2.4 Site-specific recombinases, DNA invertase Pin homologs compare
Psest_3377 +0.9 1.5 FKBP-type peptidyl-prolyl cis-trans isomerases 2 compare
Psest_0225 +0.9 1.2 Predicted permease, DMT superfamily compare
Psest_3842 +0.8 2.5 Transcriptional regulators compare
Psest_3226 +0.8 1.5 Predicted membrane protein compare
Psest_1997 +0.8 1.7 6-phosphogluconolactonase compare
Psest_3338 +0.8 2.0 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain compare
Psest_1888 +0.8 1.4 Sua5/YciO/YrdC/YwlC family protein compare
Psest_4370 +0.8 1.9 Multisubunit Na+/H+ antiporter, MnhC subunit compare
Psest_0725 +0.7 2.4 Negative regulator of beta-lactamase expression compare
Psest_3202 +0.7 3.4 Flavodoxins compare
Psest_3937 +0.7 1.2 ATP-dependent protease HslVU, ATPase subunit compare
Psest_3013 +0.7 1.2 cobyrinic acid a,c-diamide synthase compare
Psest_0814 +0.7 2.1 MoxR-like ATPases compare
Psest_1540 +0.7 1.9 biotin-dependent carboxylase uncharacterized domain compare
Psest_4151 +0.7 1.9 Flagellar hook capping protein compare
Psest_3697 +0.7 0.5 Outer membrane lipoprotein carrier protein LolA. compare
Psest_4315 +0.7 1.3 ABC-type metal ion transport system, permease component compare
Psest_0277 +0.7 1.3 non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family compare
Psest_0298 +0.7 4.1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_1543 +0.7 2.2 Predicted transcription regulator, contains HTH domain (MarR family) compare
Psest_0520 +0.6 1.0 hypothetical protein compare
Psest_2786 +0.6 1.3 Domain of unknown function (DUF3597). compare
Psest_0020 +0.6 2.5 K+ transport systems, NAD-binding component compare
Psest_4110 +0.6 4.7 Deoxycytidylate deaminase compare
Psest_1919 +0.6 1.9 Uncharacterized membrane protein (homolog of Drosophila rhomboid) compare
Psest_1382 +0.6 2.0 Transcription elongation factor compare
Psest_3562 +0.6 1.8 ABC-type antimicrobial peptide transport system, ATPase component compare
Psest_3739 +0.6 2.4 Small-conductance mechanosensitive channel compare
Psest_4221 +0.6 2.8 homoserine kinase, Neisseria type compare
Psest_1574 +0.6 1.2 phenazine biosynthesis protein PhzF family compare
Psest_2341 +0.6 2.9 Lipase chaperone compare
Psest_2048 +0.6 1.9 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_4314 +0.6 1.8 ABC-type metal ion transport system, ATPase component compare
Psest_0378 +0.6 0.7 Lactate dehydrogenase and related dehydrogenases compare
Psest_1733 +0.6 1.5 flagellar biosynthetic protein FliQ compare
Psest_1399 +0.6 3.7 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components compare
Psest_1524 +0.6 2.3 Sel1 repeat. compare
Psest_1397 +0.6 1.8 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component compare
Psest_4001 +0.6 1.9 acetylornithine deacetylase (ArgE) compare
Psest_3148 +0.6 1.4 hypothetical protein compare
Psest_4252 +0.6 1.8 Uncharacterized protein conserved in bacteria compare
Psest_3222 +0.6 2.3 Putative threonine efflux protein compare
Psest_3742 +0.6 2.2 hypothetical protein compare
Psest_0644 +0.6 1.1 siderophore ferric iron reductase, AHA_1954 family compare
Psest_4371 +0.6 2.0 Multisubunit Na+/H+ antiporter, MnhB subunit compare
Psest_4155 +0.6 2.6 Flagellin and related hook-associated proteins compare
Psest_1226 +0.5 1.8 hypothetical protein compare
Psest_1538 +0.5 2.2 Uncharacterized protein conserved in bacteria compare
Psest_3518 +0.5 0.9 Transcriptional regulators compare
Psest_3993 +0.5 3.7 alpha-L-glutamate ligases, RimK family compare
Psest_1398 +0.5 2.3 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component compare
Psest_0778 +0.5 1.7 Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin compare
Psest_0993 +0.5 3.9 Glucose-6-phosphate isomerase compare
Psest_2425 +0.5 1.7 Trk-type K+ transport systems, membrane components compare
Psest_3737 +0.5 2.4 Putative threonine efflux protein compare
Psest_0078 +0.5 0.6 hypothetical protein compare
Psest_0027 +0.5 2.0 NADPH:quinone reductase and related Zn-dependent oxidoreductases compare
Psest_3519 +0.5 1.0 Uncharacterized conserved protein compare
Psest_2240 +0.5 1.4 hypothetical protein compare
Psest_4137 +0.5 1.9 Uncharacterized iron-regulated membrane protein compare
Psest_2772 +0.5 3.4 MIP family channel proteins compare
Psest_1617 +0.5 1.2 Methylase involved in ubiquinone/menaquinone biosynthesis compare
Psest_0462 +0.5 4.7 Lipid A core - O-antigen ligase and related enzymes compare
Psest_3936 +0.5 0.7 ATP-dependent protease HslVU, peptidase subunit compare
Psest_3546 +0.5 0.7 Phosphatidylglycerophosphatase A and related proteins compare
Psest_1530 +0.5 2.4 Predicted membrane protein compare
Psest_2962 +0.5 3.5 Flagellar basal body L-ring protein compare
Psest_0708 +0.5 1.4 outer membrane assembly lipoprotein YfiO compare
Psest_2520 +0.5 1.4 Predicted SAM-dependent methyltransferase compare
Psest_2038 +0.5 2.6 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_2703 +0.5 2.6 ATPases involved in chromosome partitioning compare
Psest_2304 +0.5 1.2 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family compare
Psest_0147 +0.5 2.4 Acetyltransferase, GNAT family. compare
Psest_4166 +0.5 1.9 Flagellar biosynthesis/type III secretory pathway chaperone compare
Psest_2773 +0.5 3.4 glycerol kinase compare
Psest_2940 +0.5 2.2 Predicted membrane protein compare
Psest_3399 +0.5 1.1 Uncharacterized protein conserved in bacteria compare
Psest_3557 +0.5 2.0 Predicted redox protein, regulator of disulfide bond formation compare
Psest_0570 +0.5 1.6 hypothetical protein compare
Psest_3408 +0.4 3.2 Predicted transcriptional regulators compare
Psest_0592 +0.4 1.1 hypothetical protein compare
Psest_3422 +0.4 1.8 hypothetical protein compare
Psest_0409 +0.4 1.3 Putative homoserine kinase type II (protein kinase fold) compare
Psest_1223 +0.4 2.9 1,4-dihydroxy-2-naphthoate octaprenyltransferase compare
Psest_2293 +0.4 1.1 hypothetical protein compare
Psest_3413 +0.4 1.6 hypothetical protein compare
Psest_1870 +0.4 1.0 Transcriptional regulators compare
Psest_2960 +0.4 3.0 flagellar rod assembly protein/muramidase FlgJ compare
Psest_1636 +0.4 1.7 putative transporter, required for glycine utilization (from data) compare
Psest_2965 +0.4 4.0 fagellar hook-basal body proteins compare
Psest_2565 +0.4 1.3 Transcriptional regulator compare
Psest_0461 +0.4 2.4 Glycosyltransferase involved in LPS biosynthesis compare
Psest_0536 +0.4 1.3 thiamine-phosphate pyrophosphorylase compare
Psest_1463 +0.4 0.9 SufE protein probably involved in Fe-S center assembly compare
Psest_1720 +0.4 3.3 flagellar motor switch protein FliG compare
Psest_1118 +0.4 1.1 Predicted Fe-S-cluster oxidoreductase compare
Psest_2863 +0.4 2.3 Transcriptional regulator compare
Psest_0045 +0.4 1.7 hypothetical protein compare
Psest_3641 +0.4 3.4 Predicted membrane protein compare
Psest_4273 +0.4 3.2 Lysophospholipase compare
Psest_2268 +0.4 2.0 Alcohol dehydrogenase, class IV compare
Psest_2096 +0.4 1.3 Domain of unknown function (DUF1883). compare
Psest_4020 +0.4 2.8 hypothetical protein compare
Psest_3642 +0.4 3.2 ATPases of the AAA+ class compare
Psest_1125 +0.4 1.9 Protein of unknown function (DUF3509). compare
Psest_1206 +0.4 1.2 ABC-type Mn2+/Zn2+ transport systems, permease components compare
Psest_0266 +0.4 2.7 thiamine biosynthesis protein ThiS compare
Psest_0320 +0.4 1.3 ABC-type multidrug transport system, ATPase component compare
Psest_3429 +0.4 2.3 hypothetical protein compare
Psest_0455 +0.4 2.3 ADP-heptose:LPS heptosyltransferase compare
Psest_1816 +0.4 2.3 hypothetical protein compare
Psest_1249 +0.4 2.7 serine O-acetyltransferase compare
Psest_2039 +0.4 2.4 PQQ-dependent catabolism-associated CXXCW motif protein compare
Psest_2024 +0.4 3.2 isocitrate dehydrogenase, NADP-dependent, prokaryotic type compare
Psest_1279 +0.4 1.9 hypothetical protein compare
Psest_0296 +0.4 2.3 glutathione synthetase, prokaryotic compare
Psest_3080 +0.4 1.2 AraC-type DNA-binding domain-containing proteins compare
Psest_2966 +0.4 2.6 Flagellar hook capping protein compare
Psest_0318 +0.4 2.2 NAD-dependent DNA ligase (contains BRCT domain type II) compare
Psest_2885 +0.4 1.0 Acyl carrier protein compare
Psest_3490 +0.4 1.1 Signal transduction histidine kinase, nitrate/nitrite-specific compare
Psest_3365 +0.4 1.2 Predicted membrane protein compare
Psest_3396 +0.4 3.3 Predicted ATP-dependent protease compare
Psest_0434 +0.4 3.2 hypothetical protein compare
Psest_0292 +0.4 1.8 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase compare
Psest_2605 +0.4 1.3 transcriptional activator RfaH compare
Psest_2281 +0.4 2.1 Phosphoserine aminotransferase compare
Psest_0910 +0.4 2.5 hypothetical protein compare
Psest_3834 +0.4 1.5 NAD(P)H-nitrite reductase compare
Psest_2923 +0.4 0.8 hypothetical protein compare
Psest_3743 +0.4 1.6 Regulator of sigma D compare
Psest_0120 +0.4 1.5 hypothetical protein compare
Psest_2513 +0.4 1.4 Predicted membrane protein compare
Psest_0428 +0.4 2.3 phosphonate ABC transporter, ATP-binding protein compare
Psest_3250 +0.4 1.5 Rho termination factor, N-terminal domain. compare
Psest_1029 +0.4 1.4 Regulator of competence-specific genes compare
Psest_3664 +0.4 1.0 Predicted phosphotransferase related to Ser/Thr protein kinases compare
Psest_2961 +0.4 1.8 Flagellar basal-body P-ring protein compare
Psest_1248 +0.4 2.6 RNA methyltransferase, TrmH family, group 1 compare
Psest_1185 +0.4 0.8 heavy metal response regulator compare
Psest_0148 +0.4 1.5 nitrate transport ATP-binding subunits C and D compare
Psest_4396 +0.4 2.2 Site-specific recombinases, DNA invertase Pin homologs compare
Psest_1386 +0.4 1.6 Na+/H+-dicarboxylate symporters compare
Psest_3969 +0.4 2.6 3-hydroxyacyl-CoA dehydrogenase compare
Psest_1824 +0.4 1.6 Sugar transferases involved in lipopolysaccharide synthesis compare
Psest_1121 +0.4 2.3 Hypoxanthine-guanine phosphoribosyltransferase compare
Psest_4383 +0.4 2.9 Site-specific recombinases, DNA invertase Pin homologs compare
Psest_3143 +0.4 2.4 Uncharacterized protein conserved in bacteria compare
Psest_3719 +0.4 2.7 type IV pilus assembly protein PilM compare
Psest_1483 +0.4 1.8 hypothetical protein compare
Psest_1514 +0.4 2.1 Glycine cleavage system regulatory protein compare
Psest_1854 +0.4 1.9 Domain of Unknown Function (DUF748). compare
Psest_3535 +0.4 1.5 hypothetical protein compare
Psest_3042 +0.4 0.9 Nitrate reductase cytochrome c-type subunit compare
Psest_2757 +0.4 0.5 hypothetical protein compare
Psest_1547 +0.4 2.3 Uncharacterized protein conserved in bacteria compare
Psest_3409 +0.4 1.8 hypothetical protein compare
Psest_4268 +0.4 2.1 tripartite ATP-independent periplasmic transporter solute receptor, DctP family compare
Psest_4009 +0.4 1.8 conserverd hypothetical protein compare
Psest_0346 +0.4 1.0 small component of pyruvate/D-alanine transporter (TIGR03647) (from data) compare
Psest_2047 +0.3 1.3 Signal transduction histidine kinase compare
Psest_0465 +0.3 3.0 Acetyltransferase (isoleucine patch superfamily) compare
Psest_3533 +0.3 1.8 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_1082 +0.3 0.6 Enoyl-CoA hydratase/carnithine racemase compare
Psest_3355 +0.3 1.3 fructose-specific PTS system (fructose 1-phosphate forming), EI, Hpr, and EII-A components (from data) compare
Psest_0440 +0.3 1.8 hypothetical protein compare
Psest_0837 +0.3 0.9 Putative lipid carrier protein compare
Psest_3684 +0.3 2.3 Di- and tricarboxylate transporters compare
Psest_1813 +0.3 2.7 pseudaminic acid biosynthesis-associated protein PseG compare
Psest_4004 +0.3 0.9 Uncharacterized conserved protein compare
Psest_1139 +0.3 1.5 PAS domain S-box compare
Psest_3910 +0.3 0.3 Uncharacterized protein conserved in bacteria compare
Psest_1879 +0.3 1.2 Trk-type K+ transport systems, membrane components compare
Psest_0281 +0.3 2.7 Dynamin family. compare
Psest_1809 +0.3 2.5 Membrane protein involved in the export of O-antigen and teichoic acid compare
Psest_1178 +0.3 1.8 D-glycerate 2-kinase (EC 2.7.1.-) (from data) compare
Psest_4280 +0.3 1.5 ABC-type spermidine/putrescine transport system, permease component II compare
Psest_2280 +0.3 1.7 Predicted membrane protein compare
Psest_0501 +0.3 1.2 Predicted nucleoside-diphosphate-sugar epimerases compare
Psest_2421 +0.3 1.3 formate dehydrogenase family accessory protein FdhD compare
Psest_0601 +0.3 0.8 hypothetical protein compare
Psest_1358 +0.3 2.0 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases compare
Psest_2735 +0.3 2.6 hypothetical protein compare
Psest_4119 +0.3 1.6 hypothetical protein compare
Psest_4165 +0.3 1.9 Flagellar capping protein compare
Psest_4159 +0.3 1.9 flagellar motor stator protein MotA compare
Psest_1464 +0.3 2.2 Selenocysteine lyase compare
Psest_0584 +0.3 2.2 hypothetical protein compare


Specific Phenotypes

None in this experiment

For Pseudomonas stutzeri RCH2 in stress experiments

For stress 5-Hydroxymethylfurfural across organisms