Experiment set3IT094 for Shewanella loihica PV-4

Compare to:

LB with Carbenicillin disodium salt 50 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
Shew_2087 +5.8 17.7 hypothetical protein (RefSeq) compare
Shew_2086 +5.0 10.3 hypothetical protein (RefSeq) compare
Shew_2219 +4.6 13.9 hypothetical protein (RefSeq) compare
Shew_2939 +4.5 20.2 Serine-type D-Ala-D-Ala carboxypeptidase (RefSeq) compare
Shew_2141 +3.9 21.7 lytic murein transglycosylase (RefSeq) compare
Shew_1802 +3.8 10.2 carboxy-terminal protease (RefSeq) compare
Shew_1861 +3.7 9.6 peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysin (RefSeq) compare
Shew_2083 +3.6 12.6 hypothetical protein (RefSeq) compare
Shew_1004 +3.6 9.4 undecaprenyl pyrophosphate phosphatase (RefSeq) compare
Shew_2085 +3.5 24.4 alpha-L-glutamate ligase-like protein (RefSeq) compare
Shew_1298 guaA +3.2 15.6 bifunctional GMP synthase/glutamine amidotransferase protein (RefSeq) compare
Shew_1288 +3.2 5.2 type IV pilus biogenesis/stability protein PilW (RefSeq) compare
Shew_3273 +3.1 12.1 hypothetical protein (RefSeq) compare
Shew_3378 +3.1 6.5 Sec-independent protein translocase, TatC subunit (RefSeq) compare
Shew_0618 +2.9 4.1 hypothetical protein (RefSeq) compare
Shew_1474 +2.8 9.0 peptidase M23B (RefSeq) conserved
Shew_3427 +2.8 15.8 patatin (RefSeq) compare
Shew_3311 +2.7 24.0 RNA polymerase factor sigma-54 (RefSeq) compare
Shew_2821 +2.7 13.6 lipoprotein NlpI (RefSeq) compare
Shew_3221 +2.7 3.5 hypothetical protein (RefSeq) compare
Shew_0330 +2.5 3.6 nifR3 family TIM-barrel protein (RefSeq) compare
Shew_3580 +2.4 13.9 peptidase M16 domain-containing protein (RefSeq) compare
Shew_3377 +2.3 3.0 twin-arginine translocation protein, TatB subunit (RefSeq) compare
Shew_0799 +2.2 6.3 MarR family transcriptional regulator (RefSeq) compare
Shew_2063 +2.2 2.7 rhomboid family protein (RefSeq) compare
Shew_2637 +2.2 11.2 PII uridylyl-transferase (RefSeq) compare
Shew_3560 +2.2 16.0 signal transduction histidine kinase, nitrogen specific, NtrB (RefSeq) compare
Shew_3561 +2.1 18.0 nitrogen metabolism transcriptional regulator, NtrC, Fis family (RefSeq) compare
Shew_3581 +2.0 9.4 peptidase M16 domain-containing protein (RefSeq) compare
Shew_2082 +1.8 3.0 putative methyltransferase (RefSeq) compare
Shew_1575 +1.8 4.9 uridine kinase (RefSeq) compare
Shew_2897 +1.8 11.4 LysR family transcriptional regulator (RefSeq) compare
Shew_0950 +1.8 8.0 DEAD/DEAH box helicase domain-containing protein (RefSeq) compare
Shew_2473 +1.8 2.5 tetratricopeptide domain-containing protein (RefSeq) compare
Shew_1289 +1.7 2.5 hypothetical protein (RefSeq) compare
Shew_2187 +1.7 2.1 ribonuclease D (RefSeq) compare
Shew_1815 +1.7 2.5 hypothetical protein (RefSeq) compare
Shew_3611 +1.7 2.7 general secretion pathway protein L (RefSeq) compare
Shew_3718 +1.7 3.4 hypothetical protein (RefSeq) compare
Shew_2105 +1.7 1.5 methylated-DNA-(protein)-cysteine S-methyltransferase (RefSeq) compare
Shew_3430 +1.7 4.5 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase (RefSeq) compare
Shew_3554 glnA +1.6 7.4 glutamine synthetase (RefSeq) compare
Shew_2895 +1.6 6.3 2-dehydropantoate 2-reductase (RefSeq) compare
Shew_2476 +1.5 2.1 MotA/TolQ/ExbB proton channel (RefSeq) compare
Shew_3247 +1.5 1.3 hypothetical protein (RefSeq) compare
Shew_2837 +1.5 1.8 transcription elongation factor GreA (RefSeq) compare
Shew_3388 +1.5 1.1 hypothetical protein (RefSeq) compare
Shew_1941 +1.5 7.7 signal peptide peptidase SppA, 67K type (RefSeq) compare
Shew_1515 +1.5 4.2 Na+/H+ antiporter NhaC (RefSeq) compare
Shew_2786 +1.5 2.3 sterol-binding domain-containing protein (RefSeq) compare
Shew_3612 +1.5 3.1 general secretion pathway protein K (RefSeq) compare
Shew_2496 +1.5 4.3 phage shock protein A, PspA (RefSeq) compare
Shew_2648 +1.4 3.1 GCN5-related N-acetyltransferase (RefSeq) compare
Shew_3618 +1.4 4.8 general secretory pathway protein E (RefSeq) compare
Shew_3499 +1.4 6.2 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) compare
Shew_3498 rpoZ +1.4 5.1 DNA-directed RNA polymerase subunit omega (RefSeq) compare
Shew_1574 +1.4 4.4 ATP-binding Mrp/Nbp35 family protein (RefSeq) compare
Shew_1577 +1.4 1.2 aminotransferase, class IV (RefSeq) compare
Shew_3619 +1.4 4.2 general secretion pathway protein D (RefSeq) compare
Shew_0867 +1.4 1.6 malate dehydrogenase (RefSeq) compare
Shew_3442 +1.3 1.1 hypothetical protein (RefSeq) compare
Shew_1006 +1.3 2.1 ErfK/YbiS/YcfS/YnhG family protein (RefSeq) compare
Shew_2572 +1.3 6.2 enoyl-CoA hydratase/isomerase (RefSeq) compare
Shew_0973 +1.2 4.2 extracellular solute-binding protein (RefSeq) compare
Shew_3620 +1.2 3.0 general secretion pathway protein C (RefSeq) compare
Shew_3664 +1.2 8.7 alpha-L-glutamate ligase (RefSeq) compare
Shew_2013 +1.1 1.3 putative DNA-binding transcriptional regulator (RefSeq) compare
Shew_3807 +1.1 3.1 peptidase M23B (RefSeq) compare
Shew_3131 +1.1 3.8 poly(A) polymerase (RefSeq) compare
Shew_2022 +1.1 0.9 recombination factor protein RarA (RefSeq) compare
Shew_0466 +1.1 6.4 acriflavin resistance protein (RefSeq) compare
Shew_3431 aceE +1.1 8.7 pyruvate dehydrogenase subunit E1 (RefSeq) compare
Shew_0885 djlA +1.1 1.4 DNA-J like membrane chaperone protein (RefSeq) compare
Shew_2181 +1.0 1.8 hypothetical protein (RefSeq) compare
Shew_1769 +1.0 1.2 NapD family protein (RefSeq) compare
Shew_1427 +1.0 2.2 3'(2'),5'-bisphosphate nucleotidase (RefSeq) compare
Shew_2236 +1.0 1.9 adenine phosphoribosyltransferase (RefSeq) compare
Shew_1007 +1.0 0.8 major outer membrane lipoprotein, putative (RefSeq) compare
Shew_3610 +1.0 1.1 general secretion pathway M protein (RefSeq) compare
Shew_1036 +1.0 7.6 putative adenylate/guanylate cyclase (RefSeq) compare
Shew_2751 rdgC +1.0 2.9 recombination associated protein (RefSeq) compare
Shew_1416 +1.0 7.4 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase (RefSeq) compare
Shew_2385 +1.0 5.2 TonB-dependent receptor, plug (RefSeq) compare
Shew_3632 +1.0 7.0 sulfatase (RefSeq) compare
Shew_0738 +1.0 0.7 NTPase (RefSeq) compare
Shew_0833 +1.0 1.2 hypoxanthine-guanine phosphoribosyltransferase (RefSeq) compare
Shew_2565 +1.0 1.6 hypothetical protein (RefSeq) compare
Shew_3613 +1.0 2.6 general secretion pathway protein J (RefSeq) compare
Shew_0621 +1.0 2.8 hypothetical protein (RefSeq) compare
Shew_0728 +1.0 8.2 dihydroorotase (RefSeq) compare
Shew_3271 +1.0 4.7 galactokinase (RefSeq) compare
Shew_2044 +1.0 2.2 ecotin precursor (RefSeq) compare
Shew_1801 +0.9 1.3 putative solute/DNA competence effector (RefSeq) compare
Shew_3432 pdhR +0.9 2.3 transcriptional regulator PdhR (RefSeq) compare
Shew_1583 yebU +0.9 1.0 rRNA (cytosine-C(5)-)-methyltransferase RsmF (RefSeq) compare
Shew_1606 +0.9 0.7 hypothetical protein (RefSeq) compare
Shew_3255 +0.9 1.0 hypothetical protein (RefSeq) compare
Shew_3324 +0.9 2.2 hypothetical protein (RefSeq) compare
Shew_1820 prpB +0.9 4.6 2-methylisocitrate lyase (RefSeq) compare
Shew_1814 +0.9 4.2 ABC transporter ATPase component (RefSeq) compare
Shew_1287 +0.9 2.1 hypothetical protein (RefSeq) compare
Shew_3729 +0.9 1.1 coproporphyrinogen III oxidase (RefSeq) compare
Shew_0281 +0.9 6.0 phospholipid/glycerol acyltransferase (RefSeq) compare
Shew_3696 +0.9 2.4 CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase (RefSeq) compare
Shew_1119 +0.9 2.7 glucose/galactose transporter (RefSeq) compare
Shew_0301 +0.9 1.0 AsnC family transcriptional regulator (RefSeq) compare
Shew_3697 +0.9 3.2 glycosyl transferase family protein (RefSeq) compare
Shew_0661 +0.9 1.1 hypothetical protein (RefSeq) compare
Shew_3222 +0.8 3.4 protein of unknown function DUF335, SprT (RefSeq) compare
Shew_3695 +0.8 1.0 cytidyltransferase-like protein (RefSeq) compare
Shew_1050 +0.8 4.7 sigma E regulatory protein, MucB/RseB (RefSeq) compare
Shew_0731 +0.8 2.1 protein of unknown function DUF395, YeeE/YedE (RefSeq) compare
Shew_1548 +0.8 2.2 hypothetical protein (RefSeq) compare
Shew_2043 +0.8 1.6 cation diffusion facilitator family transporter (RefSeq) compare
Shew_2324 +0.8 1.3 type IV pilus assembly PilZ (RefSeq) compare
Shew_1518 +0.8 1.3 hypothetical protein (RefSeq) compare
Shew_1925 +0.8 4.7 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) (RefSeq) compare
Shew_0830 +0.8 0.9 LrgB family protein (RefSeq) compare
Shew_2072 +0.8 0.9 endonuclease III (RefSeq) compare
Shew_3604 +0.8 4.8 hypothetical protein (RefSeq) compare
Shew_1365 +0.8 0.9 flagellar hook-basal body complex subunit FliE (RefSeq) compare
Shew_1436 phhB +0.8 2.2 pterin-4-alpha-carbinolamine dehydratase (RefSeq) compare
Shew_2000 +0.8 1.4 glyceraldehyde-3-phosphate dehydrogenase (RefSeq) compare
Shew_2918 +0.8 0.7 hypothetical protein (RefSeq) compare
Shew_2188 +0.8 3.8 long-chain-fatty-acid--CoA ligase (RefSeq) compare
Shew_3274 +0.8 2.2 alcohol dehydrogenase (RefSeq) compare
Shew_1304 +0.8 0.8 cyd operon protein YbgT (RefSeq) compare
Shew_0369 +0.8 1.9 cytochrome C oxidase subunit IV (RefSeq) compare
Shew_1353 flgJ +0.8 2.6 peptidoglycan hydrolase (RefSeq) compare
Shew_2414 +0.8 1.5 ATP-NAD/AcoX kinase (RefSeq) compare
Shew_2354 +0.8 1.5 hypothetical protein (RefSeq) compare
Shew_1926 +0.7 1.5 transketolase, central region (RefSeq) compare
Shew_2775 +0.7 2.8 MATE efflux family protein (RefSeq) compare
Shew_1444 +0.7 1.5 dicarboxylate TRAP transporter (succinate, fumarate, L-malate, and alpha-ketoglutarate), large permease component (from data) compare
Shew_1547 +0.7 1.1 phospho-2-dehydro-3-deoxyheptonate aldolase (RefSeq) compare
Shew_0536 +0.7 2.7 tRNA-dihydrouridine synthase A (RefSeq) compare
Shew_0468 +0.7 2.5 LysR family transcriptional regulator (RefSeq) compare
Shew_0261 +0.7 0.6 hypothetical protein (RefSeq) compare
Shew_1932 cls +0.7 2.8 cardiolipin synthetase (RefSeq) compare
Shew_2944 +0.7 2.6 hypothetical protein (RefSeq) compare
Shew_3487 pyrE +0.7 4.0 orotate phosphoribosyltransferase (RefSeq) compare
Shew_0395 +0.7 1.2 methylation site containing protein (RefSeq) compare
Shew_1037 +0.7 2.9 DNA mismatch repair protein (RefSeq) compare
Shew_3122 +0.7 0.6 PepSY-associated TM helix domain-containing protein (RefSeq) compare
Shew_2165 +0.7 1.2 aldose 1-epimerase (RefSeq) compare
Shew_0594 +0.7 1.6 hypothetical protein (RefSeq) compare
Shew_0191 +0.7 1.5 cytochrome c, class I (RefSeq) compare
Shew_1660 +0.7 0.7 GCN5-related N-acetyltransferase (RefSeq) compare
Shew_3260 +0.7 2.7 porin (RefSeq) compare
Shew_1758 +0.7 2.1 hydrogenase assembly chaperone hypC/hupF (RefSeq) compare
Shew_0554 +0.7 0.9 glycerophosphoryl diester phosphodiesterase (RefSeq) compare
Shew_1453 +0.7 1.6 methylated-DNA--protein-cysteinemethyltransferase (RefSeq) compare
Shew_1867 +0.7 2.1 hypothetical protein (RefSeq) compare
Shew_1667 +0.7 1.6 acetyl-CoA acetyltransferase (RefSeq) compare
Shew_1793 +0.7 3.7 vault protein inter-alpha-trypsin subunit (RefSeq) compare
Shew_1819 +0.7 1.5 GntR family transcriptional regulator (RefSeq) compare
Shew_1281 +0.7 1.3 hypothetical protein (RefSeq) compare
Shew_0848 +0.7 0.6 hypothetical protein (RefSeq) compare
Shew_2860 +0.7 2.5 acyl-CoA dehydrogenase domain-containing protein (RefSeq) compare
Shew_1906 +0.7 1.6 GCN5-related N-acetyltransferase (RefSeq) compare
Shew_0877 apaH +0.6 1.8 diadenosine tetraphosphatase (RefSeq) compare
Shew_0569 +0.6 1.0 HflC protein (RefSeq) compare
Shew_0762 +0.6 1.6 hypothetical protein (RefSeq) compare
Shew_0461 +0.6 3.1 hypothetical protein (RefSeq) compare
Shew_2263 +0.6 1.1 methyl-accepting chemotaxis sensory transducer (RefSeq) compare
Shew_1678 +0.6 1.0 hypothetical protein (RefSeq) compare
Shew_3007 +0.6 1.5 LysR family transcriptional regulator (RefSeq) compare
Shew_1473 +0.6 2.2 hypothetical protein (RefSeq) compare
Shew_3483 dut +0.6 0.8 deoxyuridine 5'-triphosphate nucleotidohydrolase (RefSeq) compare
Shew_0467 +0.6 2.7 RND family efflux transporter MFP subunit (RefSeq) compare
Shew_0091 +0.6 2.2 molybdopterin biosynthesis MoaE (RefSeq) compare
Shew_1076 +0.6 1.6 Trp operon repressor (RefSeq) compare
Shew_1898 +0.6 0.8 ApbE family lipoprotein (RefSeq) compare
Shew_0537 +0.6 0.6 hypothetical protein (RefSeq) compare
Shew_1785 +0.6 2.6 band 7 protein (RefSeq) compare
Shew_3710 tdh +0.6 3.8 L-threonine 3-dehydrogenase (RefSeq) compare
Shew_3500 +0.6 1.1 putative endoribonuclease L-PSP (RefSeq) compare
Shew_2089 +0.6 2.6 SrpA-related protein (RefSeq) compare
Shew_1810 +0.6 3.1 dihydroorotate dehydrogenase 2 (RefSeq) compare
Shew_1869 +0.6 2.4 hypothetical protein (RefSeq) compare
Shew_1978 +0.6 0.5 hypothetical protein (RefSeq) compare
Shew_3617 +0.6 0.5 general secretion pathway protein F (RefSeq) compare
Shew_0951 +0.6 2.3 response regulator receiver modulated diguanylate phosphodiesterase (RefSeq) compare
Shew_0469 +0.6 0.4 pentapeptide repeat-containing protein (RefSeq) compare
Shew_1920 +0.6 2.4 alpha/beta hydrolase fold (RefSeq) compare
Shew_2415 +0.6 0.8 major facilitator transporter (RefSeq) compare
Shew_1445 +0.6 0.4 dicarboxylate TRAP transporter (succinate, fumarate, L-malate, and alpha-ketoglutarate), small permease component (from data) compare
Shew_1417 +0.6 3.3 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase (RefSeq) compare
Shew_1865 +0.6 1.6 phosphoenolpyruvate-protein phosphotransferase (RefSeq) compare
Shew_2841 +0.6 1.9 peptidylprolyl isomerase, FKBP-type (RefSeq) compare
Shew_2934 +0.6 0.7 SPOUT methyltransferase superfamily protein (RefSeq) compare
Shew_2119 +0.6 1.6 methyl-accepting chemotaxis sensory transducer (RefSeq) compare
Shew_2135 ushA +0.6 1.3 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor (RefSeq) compare
Shew_2458 +0.6 0.5 glutathione S-transferase domain-containing protein (RefSeq) compare
Shew_2481 +0.6 1.7 porin (RefSeq) compare
Shew_1418 +0.6 2.5 UTP-glucose-1-phosphate uridylyltransferase GalU (RefSeq) compare
Shew_2270 +0.6 2.1 alpha/beta hydrolase fold (RefSeq) compare
Shew_0616 +0.6 1.4 SH3 domain-containing protein (RefSeq) compare
Shew_1156 +0.6 0.9 hypothetical protein (RefSeq) compare
Shew_1162 +0.5 1.0 hypothetical protein (RefSeq) compare


Specific Phenotypes

For 7 genes in this experiment

For stress Carbenicillin disodium salt in Shewanella loihica PV-4

For stress Carbenicillin disodium salt across organisms