Experiment set3IT093 for Sphingomonas koreensis DSMZ 15582

Compare to:

LB with Cisplatin 0.01 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
Ga0059261_4122 +0.8 3.6 Gluconate 2-dehydrogenase subunit 3 compare
Ga0059261_2774 +0.7 1.7 Transcription elongation factor compare
Ga0059261_0685 +0.7 1.7 pyruvate kinase compare
Ga0059261_4185 +0.7 1.2 hypothetical protein compare
Ga0059261_1837 +0.5 1.7 Staphylococcal nuclease homologue compare
Ga0059261_0083 +0.5 1.0 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B (EC 6.3.5.-) compare
Ga0059261_1316 +0.5 0.9 hypothetical protein compare
Ga0059261_1774 +0.5 1.4 hypothetical protein compare
Ga0059261_3625 +0.5 2.6 Short-chain dehydrogenases of various substrate specificities compare
Ga0059261_1763 +0.5 2.3 hypothetical protein compare
Ga0059261_2951 +0.5 1.8 Heavy-metal resistance compare
Ga0059261_1414 +0.4 2.2 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF compare
Ga0059261_4007 +0.4 1.2 Transcriptional regulators compare
Ga0059261_3909 +0.4 2.0 Predicted membrane protein compare
Ga0059261_3016 +0.4 2.1 hypothetical protein compare
Ga0059261_3635 +0.4 2.1 Predicted integral membrane protein compare
Ga0059261_0045 +0.4 1.9 hypothetical protein compare
Ga0059261_1122 +0.4 1.1 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Ga0059261_2892 +0.4 1.4 hypothetical protein compare
Ga0059261_3785 +0.4 2.5 hypothetical protein compare
Ga0059261_0208 +0.4 2.1 Response regulator receiver domain compare
Ga0059261_1772 +0.4 1.3 MobA/MobL family compare
Ga0059261_0340 +0.4 2.0 Bacterial protein of unknown function (DUF937) compare
Ga0059261_2309 +0.4 2.2 transcriptional regulator, LacI family compare
Ga0059261_0451 +0.4 1.3 hypothetical protein compare
Ga0059261_1197 +0.4 1.9 hypothetical protein compare
Ga0059261_0433 +0.4 1.8 Uncharacterized protein conserved in bacteria compare
Ga0059261_1894 +0.4 2.0 D-xylose 1-dehydrogenase (EC 1.1.1.175) (from data) compare
Ga0059261_3153 +0.4 1.1 Uncharacterized protein conserved in bacteria compare
Ga0059261_1183 +0.4 1.7 Protein of unknown function (DUF2958) compare
Ga0059261_0726 +0.4 1.2 hypothetical protein compare
Ga0059261_1443 +0.4 3.0 Hemolysins and related proteins containing CBS domains compare
Ga0059261_2658 +0.4 1.5 Transcriptional regulators compare
Ga0059261_4189 +0.4 2.3 hypothetical protein compare
Ga0059261_2277 +0.4 0.9 hypothetical protein compare
Ga0059261_3025 +0.4 1.7 Methylase involved in ubiquinone/menaquinone biosynthesis compare
Ga0059261_3233 +0.4 1.7 Uncharacterized protein conserved in bacteria compare
Ga0059261_1092 +0.4 0.6 flagellar motor switch protein FliN compare
Ga0059261_2691 +0.3 1.2 Zn-dependent dipeptidase, microsomal dipeptidase homolog compare
Ga0059261_2886 +0.3 1.4 electron transfer flavoprotein beta subunit compare
Ga0059261_0920 +0.3 1.8 rRNA methylases compare
Ga0059261_3783 +0.3 1.6 hypothetical protein compare
Ga0059261_4225 +0.3 1.8 3-isopropylmalate dehydratase, small subunit compare
Ga0059261_0976 +0.3 2.2 Aspartyl protease compare
Ga0059261_0128 +0.3 2.0 clan AA aspartic protease, TIGR02281 family compare
Ga0059261_4120 +0.3 0.7 Stress responsive A/B Barrel Domain compare
Ga0059261_3762 +0.3 1.8 Uncharacterized conserved protein compare
Ga0059261_2186 +0.3 1.8 Uncharacterized protein conserved in bacteria compare
Ga0059261_3581 +0.3 1.9 Alpha/beta hydrolase family compare
Ga0059261_2285 +0.3 0.5 Fe2+ transport system protein A compare
Ga0059261_0304 +0.3 0.7 Bacterioferritin-associated ferredoxin compare
Ga0059261_3801 +0.3 1.4 Phosphate/sulphate permeases compare
Ga0059261_4060 +0.3 0.8 Predicted membrane protein compare
Ga0059261_0059 +0.3 0.5 Stress-induced morphogen (activity unknown) compare
Ga0059261_2429 +0.3 1.3 2'-5' RNA ligase superfamily compare
Ga0059261_0441 +0.3 2.0 DNA-binding HTH domain-containing proteins compare
Ga0059261_0950 +0.3 0.9 Uncharacterized protein conserved in bacteria (DUF2336) compare
Ga0059261_0412 +0.3 1.3 DNA-binding HTH domain-containing proteins compare
Ga0059261_0464 +0.3 0.5 hypothetical protein compare
Ga0059261_3376 +0.3 2.0 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases compare
Ga0059261_2466 +0.3 2.1 DnaJ domain/DnaJ C terminal domain compare
Ga0059261_0671 +0.3 1.5 Uncharacterized conserved protein compare
Ga0059261_3928 +0.3 1.5 Predicted thioesterase compare
Ga0059261_3048 +0.3 1.4 Transcriptional regulators compare
Ga0059261_0964 +0.3 1.2 Superfamily II DNA and RNA helicases compare
Ga0059261_3638 +0.3 1.1 Predicted integral membrane protein (DUF2282) compare
Ga0059261_3356 +0.3 0.7 hypothetical protein compare
Ga0059261_1782 +0.3 1.2 Transposase DDE domain compare
Ga0059261_1950 +0.3 1.6 hypothetical protein compare
Ga0059261_1596 +0.3 1.1 CBS domain compare
Ga0059261_0493 +0.3 0.6 hypothetical protein compare
Ga0059261_0846 +0.3 1.6 Zn-dependent alcohol dehydrogenases, class III compare
Ga0059261_1214 +0.3 0.7 hypothetical protein compare
Ga0059261_2220 +0.3 1.2 exodeoxyribonuclease III (xth) compare
Ga0059261_4002 +0.3 2.0 Esterase/lipase compare
Ga0059261_1975 +0.3 1.9 hypothetical protein compare
Ga0059261_4012 +0.3 0.7 AMP nucleosidase compare
Ga0059261_3387 +0.3 1.7 hypothetical protein compare
Ga0059261_3803 +0.3 1.8 RND family efflux transporter, MFP subunit compare
Ga0059261_1057 +0.3 1.4 hypothetical protein compare
Ga0059261_3859 +0.3 0.7 MgtC family compare
Ga0059261_0749 +0.3 1.5 Membrane transporters of cations and cationic drugs compare
Ga0059261_4119 +0.3 1.8 Uracil-DNA glycosylase (EC 3.2.2.-) compare
Ga0059261_3800 +0.3 1.1 Cold shock proteins compare
Ga0059261_2952 +0.3 1.3 RNA polymerase sigma factor, sigma-70 family compare
Ga0059261_3072 +0.3 2.0 P-type conjugative transfer ATPase TrbB compare
Ga0059261_2552 +0.3 1.3 Phosphotransacetylase compare
Ga0059261_0227 +0.3 1.1 hypothetical protein compare
Ga0059261_1097 +0.3 1.1 Flagellar basal body protein compare
Ga0059261_3925 +0.3 1.5 Transcriptional regulators compare
Ga0059261_1972 +0.3 1.8 Domain of unknown function (DUF3814) compare
Ga0059261_0449 +0.3 1.2 Uncharacterized protein, homolog of Cu resistance protein CopC compare
Ga0059261_2089 +0.3 1.4 flagellar basal-body rod protein FlgB compare
Ga0059261_3034 +0.3 1.9 Cation efflux family compare
Ga0059261_3407 +0.3 1.8 Superfamily II DNA and RNA helicases compare
Ga0059261_0880 +0.3 1.8 Tetratricopeptide repeat compare
Ga0059261_0754 +0.3 1.8 Glutathione S-transferase compare
Ga0059261_2708 +0.3 0.8 hypothetical protein compare
Ga0059261_0239 +0.3 0.5 tryptophan synthase, alpha chain (EC 4.2.1.20) compare
Ga0059261_2413 +0.3 0.7 hypothetical protein compare
Ga0059261_4234 +0.2 1.9 Multidrug resistance efflux pump compare
Ga0059261_3440 +0.2 0.6 hypothetical protein compare
Ga0059261_0306 +0.2 1.4 FOG: HPt domain compare
Ga0059261_0220 +0.2 1.7 L-serine dehydratase, iron-sulfur-dependent, single chain form compare
Ga0059261_1021 +0.2 0.7 hypothetical protein compare
Ga0059261_4094 +0.2 1.7 Sulfotransferase domain compare
Ga0059261_3085 +0.2 0.8 Predicted transcriptional regulators compare
Ga0059261_2663 +0.2 0.6 Domain of unknown function (DUF718) compare
Ga0059261_4100 +0.2 1.8 Dolichyl-phosphate-mannose-protein mannosyltransferase compare
Ga0059261_2916 +0.2 1.1 P-type conjugative transfer protein TrbJ compare
Ga0059261_0510 +0.2 1.9 Beta-glucosidase-related glycosidases compare
Ga0059261_0141 +0.2 1.3 transcriptional regulator, LysR family compare
Ga0059261_1213 +0.2 0.9 hypothetical protein compare
Ga0059261_3230 +0.2 1.4 hypothetical protein compare
Ga0059261_3795 +0.2 1.5 hypothetical protein compare
Ga0059261_2897 +0.2 1.0 hypothetical protein compare
Ga0059261_0742 +0.2 1.4 Uncharacterized small membrane protein compare
Ga0059261_3301 +0.2 1.3 Cyanate permease compare
Ga0059261_0223 +0.2 0.8 Peptidase inhibitor I78 family compare
Ga0059261_0625 +0.2 1.0 nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) compare
Ga0059261_4078 +0.2 1.2 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases compare
Ga0059261_2183 +0.2 1.7 Uncharacterized conserved protein compare
Ga0059261_3755 +0.2 0.6 Protein of unknown function (DUF2798) compare
Ga0059261_1768 +0.2 0.5 Sigma-70 region 2 compare
Ga0059261_2626 +0.2 1.6 transcriptional regulator, DeoR family compare
Ga0059261_0191 +0.2 1.4 hypothetical protein compare
Ga0059261_2461 +0.2 1.3 hypothetical protein compare
Ga0059261_1486 +0.2 1.7 NAD-dependent aldehyde dehydrogenases compare
Ga0059261_3825 +0.2 1.3 thiol reductant ABC exporter, CydD subunit compare
Ga0059261_1081 +0.2 1.8 Methyl-accepting chemotaxis protein compare
Ga0059261_4167 +0.2 1.7 Outer membrane protein and related peptidoglycan-associated (lipo)proteins compare
Ga0059261_2063 +0.2 0.8 Flagellar biosynthesis protein, FliO compare
Ga0059261_3011 +0.2 1.1 arsenate reductase (glutaredoxin) compare
Ga0059261_0956 +0.2 1.6 Uncharacterized protein conserved in bacteria compare
Ga0059261_0635 +0.2 1.7 choice-of-anchor A domain compare
Ga0059261_2171 +0.2 1.5 Uncharacterized protein, similar to the N-terminal domain of Lon protease compare
Ga0059261_1059 +0.2 1.5 ABC-type uncharacterized transport system, ATPase component compare
Ga0059261_1116 +0.2 1.8 Response regulator receiver domain compare
Ga0059261_1478 +0.2 0.8 Predicted dioxygenase of extradiol dioxygenase family compare
Ga0059261_3365 +0.2 1.1 hypothetical protein compare
Ga0059261_2029 +0.2 1.4 diguanylate cyclase (GGDEF) domain compare
Ga0059261_3834 +0.2 1.3 Molecular chaperone (small heat shock protein) compare
Ga0059261_1732 +0.2 0.9 Flagellar hook capping protein - N-terminal region compare
Ga0059261_1050 +0.2 0.6 hypothetical protein compare
Ga0059261_1181 +0.2 0.7 hypothetical protein compare
Ga0059261_0359 +0.2 1.4 transcriptional regulator, HxlR family compare
Ga0059261_0812 +0.2 1.1 Short-chain alcohol dehydrogenase of unknown specificity compare
Ga0059261_3491 +0.2 1.5 hypothetical protein compare
Ga0059261_4030 +0.2 1.4 glutamate N-acetyltransferase (EC 2.3.1.35) compare
Ga0059261_2503 +0.2 0.8 Predicted SPOUT methyltransferase compare
Ga0059261_0893 +0.2 1.1 inosine-5'-monophosphate dehydrogenase compare
Ga0059261_0452 +0.2 1.2 Predicted membrane protein compare
Ga0059261_0684 +0.2 0.6 Uncharacterized protein conserved in bacteria compare
Ga0059261_2950 +0.2 1.5 hypothetical protein compare
Ga0059261_1519 +0.2 1.1 NUDIX domain compare
Ga0059261_4001 +0.2 1.3 NTP pyrophosphohydrolases including oxidative damage repair enzymes compare
Ga0059261_0344 +0.2 0.9 Molecular chaperone (small heat shock protein) compare
Ga0059261_0266 +0.2 0.5 hypothetical protein compare
Ga0059261_0267 +0.2 0.7 Predicted membrane protein compare
Ga0059261_2895 +0.2 1.3 Type IV secretory pathway, protease TraF compare
Ga0059261_0597 +0.2 0.6 hypothetical protein compare
Ga0059261_4134 +0.2 0.7 tRNA compare
Ga0059261_2159 +0.2 1.2 Enoyl-CoA hydratase/carnithine racemase compare
Ga0059261_3227 +0.2 0.6 GTP-binding protein YchF compare
Ga0059261_1169 +0.2 0.9 hypothetical protein compare
Ga0059261_1556 +0.2 1.3 Predicted phosphohydrolases compare
Ga0059261_0600 +0.2 1.1 CDP-glucose 4,6-dehydratase compare
Ga0059261_3015 +0.2 1.0 hypothetical protein compare
Ga0059261_3857 +0.2 1.5 uracil-DNA glycosylase, family 4 compare
Ga0059261_2345 +0.2 1.3 hypothetical protein compare
Ga0059261_0619 +0.2 1.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Ga0059261_1610 +0.2 1.4 CBS domain/Transporter associated domain compare
Ga0059261_3219 +0.2 0.8 ubiquinol-cytochrome c reductase, iron-sulfur subunit compare
Ga0059261_3926 +0.2 1.7 L-proline dehydrogenase (EC 1.5.99.8)/delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) compare
Ga0059261_0201 +0.2 1.6 Na+/H+-dicarboxylate symporters compare
Ga0059261_2966 +0.2 0.9 2-deoxy-D-gluconate 3-dehydrogenase compare
Ga0059261_1638 +0.2 1.1 transcriptional regulator, GntR family compare
Ga0059261_1322 +0.2 1.4 RND family efflux transporter, MFP subunit compare
Ga0059261_2975 +0.2 1.4 Mannitol-1-phosphate/altronate dehydrogenases compare
Ga0059261_3696 +0.2 1.1 hypothetical protein compare
Ga0059261_2436 +0.2 1.1 hypothetical protein compare
Ga0059261_0389 +0.2 1.2 P-type conjugative transfer ATPase TrbB compare
Ga0059261_0215 +0.2 1.2 Acetyltransferase (GNAT) family compare
Ga0059261_2143 +0.2 1.0 Zn-dependent proteases compare
Ga0059261_4125 +0.2 1.3 hypothetical protein compare
Ga0059261_2907 +0.2 1.0 Acyl-CoA dehydrogenases compare
Ga0059261_2378 +0.2 0.5 phage virion morphogenesis (putative tail completion) protein compare
Ga0059261_2684 +0.2 0.6 hypothetical protein compare
Ga0059261_0884 +0.2 1.3 Transcriptional regulator compare
Ga0059261_3056 +0.2 0.8 Protein of unknown function (DUF2958) compare
Ga0059261_1557 +0.2 1.2 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase compare
Ga0059261_4058 +0.2 1.1 Uncharacterized protein conserved in bacteria compare
Ga0059261_2826 +0.2 1.3 transcriptional regulator, TetR family compare
Ga0059261_3395 +0.2 1.0 hypothetical protein compare
Ga0059261_1041 +0.2 1.2 transcriptional regulator, LysR family compare
Ga0059261_3798 +0.2 1.3 diguanylate cyclase (GGDEF) domain compare
Ga0059261_2352 +0.2 0.7 hypothetical protein compare
Ga0059261_1991 +0.2 0.8 hypothetical protein compare
Ga0059261_1525 +0.2 1.3 Domain of unknown function (DUF4349) compare
Ga0059261_0946 +0.2 1.0 Uncharacterized protein conserved in bacteria compare


Specific Phenotypes

For 7 genes in this experiment

For stress Cisplatin in Sphingomonas koreensis DSMZ 15582

For stress Cisplatin across organisms