Experiment set3IT091 for Shewanella loihica PV-4

Compare to:

LB with Chloramphenicol 5 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
Shew_0296 +3.2 6.4 heat shock protein Hsp20 (RefSeq) compare
Shew_1058 +3.1 19.8 holo-acyl-carrier-protein synthase (RefSeq) compare
Shew_1601 +2.8 8.3 3-oxoacyl-(acyl carrier protein) synthase III (RefSeq) compare
Shew_0755 +2.6 12.1 fructose-1,6-bisphosphate aldolase (RefSeq) compare
Shew_2049 +2.4 13.2 DNA-binding transcriptional regulator HexR (RefSeq) compare
Shew_1298 guaA +2.4 19.7 bifunctional GMP synthase/glutamine amidotransferase protein (RefSeq) compare
Shew_2000 +2.2 5.6 glyceraldehyde-3-phosphate dehydrogenase (RefSeq) compare
Shew_1013 +2.1 20.0 aspartate carbamoyltransferase (RefSeq) compare
Shew_2473 +2.0 3.9 tetratricopeptide domain-containing protein (RefSeq) compare
Shew_1823 +2.0 7.9 putative AcnD-accessory protein PrpF (RefSeq) compare
Shew_0728 +2.0 17.0 dihydroorotase (RefSeq) compare
Shew_3487 pyrE +2.0 14.8 orotate phosphoribosyltransferase (RefSeq) compare
Shew_2572 +2.0 8.2 enoyl-CoA hydratase/isomerase (RefSeq) compare
Shew_2476 +1.9 3.4 MotA/TolQ/ExbB proton channel (RefSeq) compare
Shew_0421 +1.9 1.7 phage shock protein C, PspC (RefSeq) compare
Shew_1563 +1.8 7.8 isocitrate dehydrogenase, NADP-dependent (RefSeq) compare
Shew_2906 +1.8 4.8 hypothetical protein (RefSeq) compare
Shew_1810 +1.8 10.1 dihydroorotate dehydrogenase 2 (RefSeq) compare
Shew_2642 +1.7 6.2 flavodoxin (RefSeq) compare
Shew_1224 +1.6 12.0 sodium:dicarboxylate symporter (RefSeq) compare
Shew_2086 +1.6 3.6 hypothetical protein (RefSeq) compare
Shew_3695 +1.6 2.8 cytidyltransferase-like protein (RefSeq) compare
Shew_2837 +1.6 2.5 transcription elongation factor GreA (RefSeq) compare
Shew_3499 +1.6 7.9 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) compare
Shew_0618 +1.5 3.0 hypothetical protein (RefSeq) compare
Shew_3273 +1.5 5.5 hypothetical protein (RefSeq) compare
Shew_1819 +1.5 4.9 GntR family transcriptional regulator (RefSeq) compare
Shew_3696 +1.5 4.3 CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase (RefSeq) compare
Shew_2174 +1.5 3.3 fatty acid metabolism regulator (RefSeq) compare
Shew_1341 +1.5 7.1 anti-sigma-28 factor, FlgM (RefSeq) compare
Shew_2349 +1.5 5.8 integral membrane sensor signal transduction histidine kinase (RefSeq) compare
Shew_2839 +1.4 13.2 carbamoyl phosphate synthase small subunit (RefSeq) compare
Shew_2087 +1.4 4.3 hypothetical protein (RefSeq) compare
Shew_1092 +1.4 11.1 amino acid carrier protein (RefSeq) compare
Shew_2838 carB +1.4 12.4 carbamoyl phosphate synthase large subunit (RefSeq) compare
Shew_0383 +1.4 6.7 malate dehydrogenase (RefSeq) compare
Shew_3410 +1.3 9.4 permease (RefSeq) compare
Shew_0534 +1.3 5.6 major facilitator transporter (RefSeq) compare
Shew_2573 +1.3 6.9 carbamoyl-phosphate synthase L chain, ATP-binding (RefSeq) compare
Shew_3681 +1.3 10.4 integral membrane sensor signal transduction histidine kinase (RefSeq) compare
Shew_2785 +1.2 1.6 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein (RefSeq) compare
Shew_3660 +1.2 10.6 glutathione reductase (RefSeq) compare
Shew_1287 +1.2 3.3 hypothetical protein (RefSeq) compare
Shew_2907 +1.2 2.3 invasion gene expression up-regulator, SirB (RefSeq) compare
Shew_2022 +1.2 1.2 recombination factor protein RarA (RefSeq) compare
Shew_3682 +1.2 8.3 two component, sigma54 specific, Fis family transcriptional regulator (RefSeq) compare
Shew_3302 +1.2 2.4 hypothetical protein (RefSeq) compare
Shew_1202 +1.2 6.8 (p)ppGpp synthetase I, SpoT/RelA (RefSeq) compare
Shew_3697 +1.2 4.8 glycosyl transferase family protein (RefSeq) compare
Shew_0950 +1.1 3.1 DEAD/DEAH box helicase domain-containing protein (RefSeq) compare
Shew_1713 +1.1 2.1 3-oxoacyl-(acyl carrier protein) synthase III (RefSeq) compare
Shew_2219 +1.1 2.3 hypothetical protein (RefSeq) compare
Shew_1050 +1.1 7.8 sigma E regulatory protein, MucB/RseB (RefSeq) compare
Shew_2013 +1.0 2.6 putative DNA-binding transcriptional regulator (RefSeq) compare
Shew_2668 +1.0 3.9 2-nitropropane dioxygenase, NPD (RefSeq) compare
Shew_3500 +1.0 3.4 putative endoribonuclease L-PSP (RefSeq) compare
Shew_0495 +1.0 1.3 hypothetical protein (RefSeq) compare
Shew_2571 +1.0 8.0 propionyl-CoA carboxylase (RefSeq) compare
Shew_3304 +1.0 3.3 ABC transporter-related protein (RefSeq) compare
Shew_2320 +1.0 6.6 RNA methyltransferase (RefSeq) compare
Shew_1590 +1.0 0.9 2OG-Fe(II) oxygenase (RefSeq) compare
Shew_3388 +1.0 0.9 hypothetical protein (RefSeq) compare
Shew_2409 +1.0 3.2 short chain dehydrogenase (RefSeq) compare
Shew_1865 +1.0 5.4 phosphoenolpyruvate-protein phosphotransferase (RefSeq) compare
Shew_0446 +1.0 1.4 hypothetical protein (RefSeq) compare
Shew_0438 +0.9 1.1 GumN family protein (RefSeq) compare
Shew_3295 +0.9 5.5 AFG1 family ATPase (RefSeq) compare
Shew_2105 +0.9 1.0 methylated-DNA-(protein)-cysteine S-methyltransferase (RefSeq) compare
Shew_2469 +0.9 1.0 GCN5-related N-acetyltransferase (RefSeq) compare
Shew_3054 +0.9 1.6 hypothetical protein (RefSeq) compare
Shew_3708 +0.9 5.5 TetR family transcriptional regulator (RefSeq) compare
Shew_1470 +0.9 4.9 sulfatase (RefSeq) compare
Shew_0330 +0.9 1.3 nifR3 family TIM-barrel protein (RefSeq) compare
Shew_2147 +0.9 1.4 hypothetical protein (RefSeq) compare
Shew_1606 +0.9 0.9 hypothetical protein (RefSeq) compare
Shew_3718 +0.9 1.9 hypothetical protein (RefSeq) compare
Shew_3247 +0.9 0.8 hypothetical protein (RefSeq) compare
Shew_0828 +0.8 1.0 LysR family transcriptional regulator (RefSeq) compare
Shew_1021 +0.8 5.9 peptidase M23B (RefSeq) compare
Shew_0127 +0.8 2.6 LexA repressor (RefSeq) compare
Shew_3063 +0.8 1.4 glycine cleavage system protein H (RefSeq) compare
Shew_2115 +0.8 3.5 lytic transglycosylase, catalytic (RefSeq) compare
Shew_3389 +0.8 1.6 hypothetical protein (RefSeq) compare
Shew_3664 +0.8 6.3 alpha-L-glutamate ligase (RefSeq) compare
Shew_1867 +0.8 3.6 hypothetical protein (RefSeq) compare
Shew_3271 +0.8 4.9 galactokinase (RefSeq) compare
Shew_1518 +0.8 1.5 hypothetical protein (RefSeq) compare
Shew_1822 +0.8 3.0 aconitate hydratase (RefSeq) compare
Shew_1114 +0.8 1.7 SapC family protein (RefSeq) compare
Shew_3710 tdh +0.8 5.7 L-threonine 3-dehydrogenase (RefSeq) compare
Shew_1714 +0.8 1.3 alpha/beta hydrolase fold (RefSeq) compare
Shew_3709 +0.8 6.0 2-amino-3-ketobutyrate coenzyme A ligase (RefSeq) compare
Shew_1688 +0.7 3.6 TonB-dependent receptor (RefSeq) compare
Shew_2667 +0.7 5.5 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ (RefSeq) compare
Shew_2026 +0.7 2.2 alanine dehydrogenase (RefSeq) compare
Shew_1820 prpB +0.7 1.8 2-methylisocitrate lyase (RefSeq) compare
Shew_2584 +0.7 5.3 electron transfer flavoprotein beta-subunit (RefSeq) compare
Shew_2041 +0.7 2.3 hypothetical protein (RefSeq) compare
Shew_0854 +0.7 2.3 hypothetical protein (RefSeq) compare
Shew_2222 +0.7 0.9 hypothetical protein (RefSeq) compare
Shew_0412 +0.7 3.4 secretion protein HlyD family protein (RefSeq) compare
Shew_1931 +0.7 1.2 alkylphosphonate utilization operon protein PhnA (RefSeq) compare
Shew_1878 +0.7 1.3 2-nitropropane dioxygenase, NPD (RefSeq) compare
Shew_0024 +0.7 0.9 ArsR family transcriptional regulator (RefSeq) compare
Shew_0594 +0.7 1.8 hypothetical protein (RefSeq) compare
Shew_1014 +0.7 0.8 XRE family transcriptional regulator (RefSeq) compare
Shew_0659 +0.7 2.8 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (RefSeq) compare
Shew_0316 +0.7 2.8 protein of unknown function DUF513, hemX (RefSeq) compare
Shew_2730 +0.7 1.3 glutathione S-transferase domain-containing protein (RefSeq) compare
Shew_0394 +0.7 0.9 hypothetical protein (RefSeq) compare
Shew_2437 +0.7 0.9 hypothetical protein (RefSeq) compare
Shew_1960 +0.7 0.7 hypothetical protein (RefSeq) compare
Shew_0098 +0.7 4.5 integral membrane sensor signal transduction histidine kinase (RefSeq) compare
Shew_2072 +0.7 1.2 endonuclease III (RefSeq) compare
Shew_3786 +0.7 0.8 hypothetical protein (RefSeq) compare
Shew_0590 +0.7 1.9 hypothetical protein (RefSeq) compare
Shew_3444 +0.7 1.8 mutator MutT protein (RefSeq) compare
Shew_3820 +0.7 2.0 hypothetical protein (RefSeq) compare
Shew_2934 +0.7 1.0 SPOUT methyltransferase superfamily protein (RefSeq) compare
Shew_1445 +0.6 0.6 dicarboxylate TRAP transporter (succinate, fumarate, L-malate, and alpha-ketoglutarate), small permease component (from data) compare
Shew_3702 +0.6 1.4 glycosyl transferase family protein (RefSeq) compare
Shew_0738 +0.6 0.6 NTPase (RefSeq) compare
Shew_0698 +0.6 2.0 Na+/H+ antiporter NhaC (RefSeq) compare
Shew_2570 +0.6 5.1 acyl-CoA dehydrogenase domain-containing protein (RefSeq) compare
Shew_2202 +0.6 0.7 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase (RefSeq) compare
Shew_3498 rpoZ +0.6 2.3 DNA-directed RNA polymerase subunit omega (RefSeq) compare
Shew_3716 +0.6 1.8 cytochrome c, class I (RefSeq) compare
Shew_0097 +0.6 3.2 two component transcriptional regulator (RefSeq) compare
Shew_2444 +0.6 0.9 hypothetical protein (RefSeq) compare
Shew_3698 +0.6 3.9 glycosyl transferase family protein (RefSeq) compare
Shew_1078 +0.6 4.6 peptidylprolyl isomerase, FKBP-type (RefSeq) compare
Shew_0320 +0.6 2.2 frataxin family protein (RefSeq) compare
Shew_3131 +0.6 4.3 poly(A) polymerase (RefSeq) compare
Shew_2656 +0.6 3.4 4'-phosphopantetheinyl transferase (RefSeq) compare
Shew_2140 +0.6 1.1 hypothetical protein (RefSeq) compare
Shew_1488 +0.6 1.6 FAD linked oxidase domain-containing protein (RefSeq) compare
Shew_0086 +0.6 5.0 electron-transferring-flavoproteindehydrogenase (RefSeq) compare
Shew_0586 +0.6 1.4 TPR repeat-containing protein (RefSeq) compare
Shew_3622 hslO +0.6 2.4 Hsp33-like chaperonin (RefSeq) compare
Shew_1510 +0.6 0.9 peptidase M28 (RefSeq) compare
Shew_R0076 +0.6 0.8 tRNA-Asn (RefSeq) compare
Shew_2962 +0.6 2.5 malate dehydrogenase (RefSeq) compare
Shew_1423 +0.6 0.5 sulfate adenylyltransferase, large subunit (RefSeq) compare
Shew_1407 +0.6 4.7 short-chain dehydrogenase/reductase SDR (RefSeq) compare
Shew_2558 +0.6 2.0 1,4-dihydroxy-2-naphthoate octaprenyltransferase (RefSeq) compare
Shew_0615 +0.6 3.1 bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase (RefSeq) compare
Shew_2598 +0.6 1.4 hypothetical protein (RefSeq) compare
Shew_1732 +0.6 2.1 hypothetical protein (RefSeq) compare
Shew_2052 +0.6 1.6 TetR family transcriptional regulator (RefSeq) compare
Shew_2372 +0.6 1.0 small component of L-lactate and L-malate uptake system (from data) compare
Shew_3772 +0.6 0.8 thioesterase superfamily protein (RefSeq) compare
Shew_1683 +0.6 1.2 hypothetical protein (RefSeq) compare
Shew_1530 +0.5 2.1 porin (RefSeq) compare
Shew_0432 +0.5 2.2 hypothetical protein (RefSeq) compare
Shew_0799 +0.5 1.5 MarR family transcriptional regulator (RefSeq) compare
Shew_1122 +0.5 2.0 hypothetical protein (RefSeq) compare
Shew_0741 +0.5 1.9 GCN5-related N-acetyltransferase (RefSeq) compare
Shew_2496 +0.5 1.4 phage shock protein A, PspA (RefSeq) compare
Shew_1667 +0.5 1.4 acetyl-CoA acetyltransferase (RefSeq) compare
Shew_3693 +0.5 4.0 ADP-heptose--lipooligosaccharide heptosyltransferase III (RefSeq) compare
Shew_0885 djlA +0.5 0.8 DNA-J like membrane chaperone protein (RefSeq) compare
Shew_1859 +0.5 0.6 carbonate dehydratase (RefSeq) compare
Shew_3176 +0.5 0.8 regulatory protein GntR, HTH (RefSeq) compare
Shew_2327 +0.5 0.6 hypothetical protein (RefSeq) compare
Shew_3288 +0.5 2.6 23S rRNA (guanosine-2'-O-)-methyltransferase (RefSeq) compare
Shew_2665 +0.5 3.9 beta-ketoacyl synthase (RefSeq) compare
Shew_3301 +0.5 2.5 toluene tolerance family protein (RefSeq) compare
Shew_1125 +0.5 1.2 hypothetical protein (RefSeq) compare
Shew_1616 +0.5 0.7 hypothetical protein (RefSeq) compare
Shew_3240 +0.5 1.4 two component LuxR family transcriptional regulator (RefSeq) compare
Shew_1574 +0.5 1.9 ATP-binding Mrp/Nbp35 family protein (RefSeq) compare
Shew_3636 +0.5 3.0 transcription elongation factor GreB (RefSeq) compare
Shew_0225 +0.5 0.4 phosphoheptose isomerase (RefSeq) compare
Shew_3495 +0.5 1.1 hypothetical protein (RefSeq) compare
Shew_2529 +0.5 2.9 pseudouridine synthase (RefSeq) compare
Shew_2435 +0.5 1.6 sodium/proline symporter (RefSeq) compare
Shew_3080 +0.5 0.9 thiol:disulfide interchange protein, putative (RefSeq) compare
Shew_2666 +0.5 3.8 omega-3 polyunsaturated fatty acid synthase PfaB (RefSeq) compare
Shew_3562 +0.5 2.2 LysR family transcriptional regulator (RefSeq) compare
Shew_0206 +0.5 3.1 argininosuccinate lyase (RefSeq) compare
Shew_3549 +0.5 1.5 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein (RefSeq) compare
Shew_3385 uvrD +0.5 2.9 DNA-dependent helicase II (RefSeq) compare
Shew_2395 +0.5 1.4 hypothetical protein (RefSeq) compare
Shew_1657 sucC +0.5 0.8 succinyl-CoA synthetase subunit beta (RefSeq) compare
Shew_1230 +0.5 1.4 phosphoribosylaminoimidazole carboxylase, catalytic subunit (RefSeq) compare
Shew_2494 +0.5 1.2 phage shock protein C, PspC (RefSeq) compare
Shew_1716 +0.5 0.6 3-beta hydroxysteroid dehydrogenase/isomerase (RefSeq) compare
Shew_0521 metL +0.5 2.0 bifunctional aspartate kinase II/homoserine dehydrogenase II (RefSeq) compare
Shew_2905 +0.5 3.0 hypothetical protein (RefSeq) compare
Shew_0902 +0.5 2.1 (acyl-carrier-protein) S-malonyltransferase (RefSeq) compare
Shew_2695 +0.5 1.5 two component transcriptional regulator (RefSeq) compare
Shew_2799 torD +0.5 1.2 chaperone protein TorD (RefSeq) compare
Shew_1171 +0.5 2.2 glucose-1-phosphate adenylyltransferase (RefSeq) compare
Shew_1339 +0.5 0.8 hypothetical protein (RefSeq) compare
Shew_2910 +0.5 0.7 hypothetical protein (RefSeq) compare
Shew_1883 +0.5 0.5 hypothetical protein (RefSeq) compare
Shew_2347 +0.5 1.5 phosphonate ABC transporter, periplasmic phosphonate-binding protein (RefSeq) compare
Shew_0575 +0.5 0.7 glutamine amidotransferase of anthranilate synthase (RefSeq) compare
Shew_2893 +0.5 3.2 nucleotide-binding protein (RefSeq) compare
Shew_1395 +0.5 2.2 VacJ family lipoprotein (RefSeq) compare


Specific Phenotypes

For 1 genes in this experiment

For stress Chloramphenicol in Shewanella loihica PV-4

For stress Chloramphenicol across organisms