Experiment set3IT090 for Sphingomonas koreensis DSMZ 15582

Compare to:

LB with sodium fluoride 10 mM

200 most detrimental genes:

  gene name fitness t score description  
Ga0059261_0208 +1.3 6.3 Response regulator receiver domain compare
Ga0059261_3579 +1.3 4.9 hypothetical protein compare
Ga0059261_1527 +1.1 2.3 hypothetical protein compare
Ga0059261_3492 +1.1 6.0 RNA polymerase sigma factor, sigma-70 family compare
Ga0059261_0493 +1.0 2.8 hypothetical protein compare
Ga0059261_3490 +0.9 5.4 Response regulator receiver domain/Sigma-70, region 4 compare
Ga0059261_3581 +0.8 4.9 Alpha/beta hydrolase family compare
Ga0059261_1261 +0.8 2.8 hypothetical protein compare
Ga0059261_2215 +0.7 1.9 Thiamine monophosphate synthase compare
Ga0059261_0390 +0.7 1.8 Ribbon-helix-helix protein, copG family compare
Ga0059261_1985 +0.7 2.3 transcriptional regulator NrdR compare
Ga0059261_0304 +0.7 1.7 Bacterioferritin-associated ferredoxin compare
Ga0059261_0266 +0.6 1.8 hypothetical protein compare
Ga0059261_2368 +0.6 2.3 Phage baseplate assembly protein W compare
Ga0059261_2314 +0.6 2.7 Protein-disulfide isomerase compare
Ga0059261_1837 +0.6 2.2 Staphylococcal nuclease homologue compare
Ga0059261_3359 +0.6 2.4 Zn-dependent hydrolases, including glyoxylases compare
Ga0059261_3507 +0.5 4.6 His Kinase A (phospho-acceptor) domain/Response regulator receiver domain/Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase/CHASE3 domain compare
Ga0059261_1183 +0.5 2.3 Protein of unknown function (DUF2958) compare
Ga0059261_0957 +0.5 1.7 Protein of unknown function (DUF2798) compare
Ga0059261_1811 +0.5 1.6 ATP:cob(I)alamin adenosyltransferase compare
Ga0059261_0393 +0.5 1.4 hypothetical protein compare
Ga0059261_3237 +0.5 2.4 hypothetical protein compare
Ga0059261_1092 +0.5 1.1 flagellar motor switch protein FliN compare
Ga0059261_3280 +0.5 1.0 Uncharacterized conserved protein compare
Ga0059261_1831 +0.5 1.7 hypothetical protein compare
Ga0059261_3810 +0.5 2.0 Transcriptional regulators compare
Ga0059261_2222 +0.5 2.9 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family compare
Ga0059261_3518 +0.4 3.8 RND family efflux transporter, MFP subunit compare
Ga0059261_3440 +0.4 1.0 hypothetical protein compare
Ga0059261_0045 +0.4 1.8 hypothetical protein compare
Ga0059261_2514 +0.4 3.6 phosphoenolpyruvate-protein phosphotransferase compare
Ga0059261_2413 +0.4 1.2 hypothetical protein compare
Ga0059261_3345 +0.4 1.1 TlyA family rRNA methyltransferase/putative hemolysin compare
Ga0059261_1478 +0.4 1.2 Predicted dioxygenase of extradiol dioxygenase family compare
Ga0059261_2429 +0.4 1.7 2'-5' RNA ligase superfamily compare
Ga0059261_2448 +0.4 1.2 DNA protecting protein DprA compare
Ga0059261_4060 +0.4 1.4 Predicted membrane protein compare
Ga0059261_2768 +0.4 1.2 hypothetical protein compare
Ga0059261_3236 +0.4 3.5 pyruvate phosphate dikinase (EC 2.7.9.1) compare
Ga0059261_0252 +0.4 1.5 SpoIIAA-like compare
Ga0059261_3833 +0.4 1.1 hypothetical protein compare
Ga0059261_1991 +0.4 1.9 hypothetical protein compare
Ga0059261_1050 +0.4 1.1 hypothetical protein compare
Ga0059261_0918 +0.4 2.1 Phosphotransferase system, mannose/fructose-specific component IIA compare
Ga0059261_4225 +0.4 2.1 3-isopropylmalate dehydratase, small subunit compare
Ga0059261_0898 +0.4 1.4 Membrane protein implicated in regulation of membrane protease activity compare
Ga0059261_0274 +0.4 2.2 transcriptional regulator, TraR/DksA family compare
Ga0059261_1577 +0.4 3.3 L-glutamine and L-histidine transporter (from data) compare
Ga0059261_3451 +0.4 0.7 hypothetical protein compare
Ga0059261_3006 +0.4 1.8 hypothetical protein compare
Ga0059261_0069 +0.4 1.9 tRNA dimethylallyltransferase compare
Ga0059261_3347 +0.4 1.5 Domain of unknown function DUF87 compare
Ga0059261_0976 +0.4 2.3 Aspartyl protease compare
Ga0059261_2396 +0.4 2.0 hypothetical protein compare
Ga0059261_0964 +0.4 1.3 Superfamily II DNA and RNA helicases compare
Ga0059261_3940 +0.4 2.2 hypothetical protein compare
Ga0059261_1934 +0.3 1.8 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) compare
Ga0059261_2416 +0.3 2.3 TIGR00730 family protein compare
Ga0059261_1316 +0.3 0.9 hypothetical protein compare
Ga0059261_1293 +0.3 2.9 (p)ppGpp synthetase, RelA/SpoT family compare
Ga0059261_3877 +0.3 0.6 hypothetical protein compare
Ga0059261_3125 +0.3 1.0 Imidazoleglycerol-phosphate synthase compare
Ga0059261_0035 +0.3 0.7 Uncharacterized protein conserved in bacteria compare
Ga0059261_0619 +0.3 1.7 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Ga0059261_3251 +0.3 1.1 Transcriptional regulator compare
Ga0059261_0556 +0.3 1.4 Signal transduction histidine kinase compare
Ga0059261_1265 +0.3 1.3 hypothetical protein compare
Ga0059261_2099 +0.3 1.8 flagellar hook-associated protein 3 compare
Ga0059261_2593 +0.3 0.9 hypothetical protein compare
Ga0059261_1318 +0.3 1.3 Uncharacterized MobA-related protein compare
Ga0059261_0387 +0.3 1.2 Type IV secretory pathway, TrbD component compare
Ga0059261_3685 +0.3 2.3 Enoyl-CoA hydratase/carnithine racemase compare
Ga0059261_4074 +0.3 2.0 two component transcriptional regulator, LuxR family compare
Ga0059261_3368 +0.3 1.7 Predicted transcriptional regulator compare
Ga0059261_1856 +0.3 1.3 hypothetical protein compare
Ga0059261_1717 +0.3 1.0 hypothetical protein compare
Ga0059261_0444 +0.3 1.3 Heavy-metal resistance compare
Ga0059261_2132 +0.3 1.0 transcriptional regulator, BadM/Rrf2 family compare
Ga0059261_3498 +0.3 1.4 Iron-sulfur cluster assembly accessory protein compare
Ga0059261_1914 +0.3 0.8 Acetyltransferases compare
Ga0059261_0926 +0.3 1.5 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Ga0059261_1597 +0.3 1.7 hypothetical protein compare
Ga0059261_0083 +0.3 0.5 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B (EC 6.3.5.-) compare
Ga0059261_0920 +0.3 1.5 rRNA methylases compare
Ga0059261_4185 +0.3 0.5 hypothetical protein compare
Ga0059261_3838 +0.3 1.3 Hemerythrin HHE cation binding domain compare
Ga0059261_0139 +0.3 1.9 Signal transduction histidine kinase, nitrogen specific compare
Ga0059261_0685 +0.3 0.7 pyruvate kinase compare
Ga0059261_2344 +0.3 1.8 DNA modification methylase compare
Ga0059261_0596 +0.3 1.6 Cation efflux family compare
Ga0059261_1484 +0.3 1.3 hypothetical protein compare
Ga0059261_2743 +0.3 1.2 hypothetical protein compare
Ga0059261_3301 +0.3 1.2 Cyanate permease compare
Ga0059261_2270 +0.3 1.7 hypothetical protein compare
Ga0059261_2309 +0.3 1.5 transcriptional regulator, LacI family compare
Ga0059261_2503 +0.3 1.2 Predicted SPOUT methyltransferase compare
Ga0059261_2713 +0.3 0.8 hypothetical protein compare
Ga0059261_1311 +0.3 1.3 Nitroreductase compare
Ga0059261_2951 +0.3 1.0 Heavy-metal resistance compare
Ga0059261_3107 +0.3 1.6 EPS-associated transcriptional regulator, MarR family compare
Ga0059261_0270 +0.3 1.7 Uncharacterized protein conserved in bacteria compare
Ga0059261_3308 +0.3 1.1 Uncharacterized conserved protein compare
Ga0059261_4059 +0.3 1.4 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases compare
Ga0059261_3395 +0.3 1.4 hypothetical protein compare
Ga0059261_2796 +0.3 1.6 hypothetical protein compare
Ga0059261_3072 +0.3 2.0 P-type conjugative transfer ATPase TrbB compare
Ga0059261_3027 +0.3 0.8 Predicted transcriptional regulators compare
Ga0059261_1049 +0.3 1.2 PEP-CTERM protein-sorting domain compare
Ga0059261_2044 +0.3 1.9 peptide chain release factor 3 compare
Ga0059261_2929 +0.3 0.5 oxygen-dependent methionine synthase, methyltransferase component MesD (from data) compare
Ga0059261_3799 +0.3 0.9 hypothetical protein compare
Ga0059261_4195 +0.2 1.7 polysaccharide deacetylase family protein, PEP-CTERM locus subfamily compare
Ga0059261_1253 +0.2 0.7 Uncharacterized protein conserved in bacteria compare
Ga0059261_0866 +0.2 1.8 Putative threonine efflux protein compare
Ga0059261_4007 +0.2 0.6 Transcriptional regulators compare
Ga0059261_0989 +0.2 1.9 transporter, CPA2 family (TC 2.A.37) compare
Ga0059261_3891 +0.2 1.4 SapC compare
Ga0059261_2810 +0.2 1.9 Predicted metal-dependent hydrolase of the TIM-barrel fold compare
Ga0059261_0778 +0.2 1.6 RNA polymerase sigma factor, sigma-70 family compare
Ga0059261_1950 +0.2 1.7 hypothetical protein compare
Ga0059261_1241 +0.2 1.6 MerT mercuric transport protein compare
Ga0059261_2241 +0.2 1.3 Uncharacterized protein conserved in bacteria compare
Ga0059261_2053 +0.2 1.7 Mg2+ and Co2+ transporters compare
Ga0059261_0825 +0.2 1.0 Uncharacterized conserved protein compare
Ga0059261_3444 +0.2 1.8 Uncharacterized protein conserved in bacteria compare
Ga0059261_1404 +0.2 1.6 transcriptional regulator, BadM/Rrf2 family compare
Ga0059261_3583 +0.2 1.9 hypothetical protein compare
Ga0059261_0525 +0.2 0.9 Transcriptional regulator compare
Ga0059261_1420 +0.2 1.6 Protein of unknown function (DUF2490) compare
Ga0059261_1126 +0.2 1.0 Response regulator compare
Ga0059261_2091 +0.2 1.2 Flagellar hook capping protein compare
Ga0059261_3552 +0.2 1.5 hypothetical protein compare
Ga0059261_1071 +0.2 0.9 hypothetical protein compare
Ga0059261_3207 +0.2 1.3 Disulfide bond chaperones of the HSP33 family compare
Ga0059261_3261 +0.2 1.6 Protein of unknown function (DUF938) compare
Ga0059261_0256 +0.2 1.7 anthranilate synthase component I, non-proteobacterial lineages compare
Ga0059261_1077 +0.2 1.0 STAS domain compare
Ga0059261_0593 +0.2 1.3 Outer membrane protein compare
Ga0059261_1990 +0.2 1.4 Methyltransferase domain compare
Ga0059261_0832 +0.2 1.9 Predicted permease compare
Ga0059261_2078 +0.2 1.3 transcriptional regulator, ArsR family compare
Ga0059261_3332 +0.2 1.0 Predicted membrane protein compare
Ga0059261_3682 +0.2 1.5 hypothetical protein compare
Ga0059261_3274 +0.2 1.1 Glyoxalase-like domain compare
Ga0059261_1181 +0.2 0.8 hypothetical protein compare
Ga0059261_0121 +0.2 0.5 Sporulation related domain compare
Ga0059261_2227 +0.2 2.0 aminodeoxychorismate synthase, component I, bacterial clade compare
Ga0059261_3695 +0.2 1.5 Predicted metal-dependent hydrolase with the TIM-barrel fold compare
Ga0059261_3052 +0.2 1.0 Uncharacterized conserved protein (DUF2285) compare
Ga0059261_2259 +0.2 1.2 hypothetical protein compare
Ga0059261_2695 +0.2 1.7 Methyltransferase domain compare
Ga0059261_1396 +0.2 1.0 EF-hand domain pair compare
Ga0059261_3491 +0.2 1.5 hypothetical protein compare
Ga0059261_3635 +0.2 1.0 Predicted integral membrane protein compare
Ga0059261_1197 +0.2 1.0 hypothetical protein compare
Ga0059261_3023 +0.2 1.5 Predicted transcriptional regulators compare
Ga0059261_1214 +0.2 0.5 hypothetical protein compare
Ga0059261_3675 +0.2 0.9 Methyl-accepting chemotaxis protein compare
Ga0059261_2528 +0.2 0.9 Uncharacterized conserved protein compare
Ga0059261_0306 +0.2 1.2 FOG: HPt domain compare
Ga0059261_2665 +0.2 1.2 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Ga0059261_1161 +0.2 1.4 Cu(I)-responsive transcriptional regulator compare
Ga0059261_3652 +0.2 1.5 phosphate transport system regulatory protein PhoU compare
Ga0059261_3230 +0.2 1.3 hypothetical protein compare
Ga0059261_1398 +0.2 1.3 Sulfite oxidase and related enzymes compare
Ga0059261_4224 +0.2 0.5 hypothetical protein compare
Ga0059261_4046 +0.2 0.7 Response regulator receiver domain compare
Ga0059261_2746 +0.2 1.2 Predicted sugar nucleotidyltransferases compare
Ga0059261_3884 +0.2 1.0 K+-transporting ATPase, B subunit compare
Ga0059261_3161 +0.2 1.3 tol-pal system-associated acyl-CoA thioesterase compare
Ga0059261_0246 +0.2 0.5 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD compare
Ga0059261_2957 +0.2 1.5 Signal transduction histidine kinase compare
Ga0059261_3526 +0.2 1.6 hemimethylated DNA binding domain compare
Ga0059261_1496 +0.2 1.0 uroporphyrin-III C-methyltransferase compare
Ga0059261_3800 +0.2 0.8 Cold shock proteins compare
Ga0059261_3854 +0.2 1.7 dimethylhistidine N-methyltransferase compare
Ga0059261_1394 +0.2 1.4 putative efflux protein, MATE family compare
Ga0059261_3914 +0.2 1.2 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) compare
Ga0059261_1368 +0.2 0.5 hypothetical protein compare
Ga0059261_1786 +0.2 1.2 hypothetical protein compare
Ga0059261_1256 +0.2 1.3 Membrane-associated lipoprotein involved in thiamine biosynthesis compare
Ga0059261_1514 +0.2 1.4 Uncharacterized protein conserved in bacteria compare
Ga0059261_0433 +0.2 0.7 Uncharacterized protein conserved in bacteria compare
Ga0059261_0726 +0.2 0.6 hypothetical protein compare
Ga0059261_2642 +0.2 1.8 Beta-galactosidase compare
Ga0059261_0673 +0.2 1.0 hypothetical protein compare
Ga0059261_1878 +0.2 1.2 RND family efflux transporter, MFP subunit compare
Ga0059261_2914 +0.2 0.7 Type IV secretory pathway, TrbD component compare
Ga0059261_1191 +0.2 1.0 RNA polymerase sigma factor, sigma-70 family compare
Ga0059261_3909 +0.2 0.9 Predicted membrane protein compare
Ga0059261_0618 +0.2 1.4 Signal transduction histidine kinase regulating C4-dicarboxylate transport system compare
Ga0059261_2731 +0.2 0.9 transcriptional regulator, AraC family compare
Ga0059261_2390 +0.2 1.1 hypothetical protein compare
Ga0059261_2670 +0.2 1.3 Predicted kinase compare
Ga0059261_4134 +0.2 0.8 tRNA compare
Ga0059261_1999 +0.2 1.2 threonine synthase compare
Ga0059261_2728 +0.2 1.4 Glyoxalase-like domain compare
Ga0059261_0244 +0.2 0.8 FOG: CheY-like receiver compare
Ga0059261_3257 +0.2 0.8 glycine cleavage system H protein compare


Specific Phenotypes

For 1 genes in this experiment

For stress sodium fluoride in Sphingomonas koreensis DSMZ 15582

For stress sodium fluoride across organisms