Experiment set3IT088 for Sphingomonas koreensis DSMZ 15582

Compare to:

LB with Cobalt chloride hexahydrate 0.08 mM

200 most detrimental genes:

  gene name fitness t score description  
Ga0059261_1911 +2.1 6.8 Thioredoxin-like proteins and domains compare
Ga0059261_3492 +1.8 9.5 RNA polymerase sigma factor, sigma-70 family compare
Ga0059261_3490 +1.4 9.4 Response regulator receiver domain/Sigma-70, region 4 compare
Ga0059261_3579 +1.4 6.5 hypothetical protein compare
Ga0059261_0208 +1.1 5.1 Response regulator receiver domain compare
Ga0059261_0627 +1.0 2.3 cobalamin-5'-phosphate synthase (EC 2.7.8.26) compare
Ga0059261_0083 +1.0 2.0 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B (EC 6.3.5.-) compare
Ga0059261_3581 +0.9 5.1 Alpha/beta hydrolase family compare
Ga0059261_3491 +0.9 5.8 hypothetical protein compare
Ga0059261_1260 +0.8 5.5 cobaltochelatase CobT subunit (EC 6.6.1.2) compare
Ga0059261_2774 +0.8 2.0 Transcription elongation factor compare
Ga0059261_2391 +0.8 2.1 Helix-turn-helix domain compare
Ga0059261_1262 +0.8 6.2 cobaltochelatase CobS subunit (EC 6.6.1.2) compare
Ga0059261_2226 +0.7 6.3 Aspartate/tyrosine/aromatic aminotransferase compare
Ga0059261_1035 +0.6 2.0 hypothetical protein compare
Ga0059261_0266 +0.6 1.4 hypothetical protein compare
Ga0059261_4224 +0.6 1.4 hypothetical protein compare
Ga0059261_3507 +0.6 5.2 His Kinase A (phospho-acceptor) domain/Response regulator receiver domain/Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase/CHASE3 domain compare
Ga0059261_3287 +0.6 4.3 Topoisomerase IB compare
Ga0059261_1527 +0.6 1.3 hypothetical protein compare
Ga0059261_0390 +0.6 0.9 Ribbon-helix-helix protein, copG family compare
Ga0059261_3638 +0.6 1.1 Predicted integral membrane protein (DUF2282) compare
Ga0059261_1339 +0.6 1.4 hypothetical protein compare
Ga0059261_4185 +0.5 1.0 hypothetical protein compare
Ga0059261_1318 +0.5 1.8 Uncharacterized MobA-related protein compare
Ga0059261_0069 +0.5 2.6 tRNA dimethylallyltransferase compare
Ga0059261_0950 +0.5 1.8 Uncharacterized protein conserved in bacteria (DUF2336) compare
Ga0059261_3518 +0.5 4.4 RND family efflux transporter, MFP subunit compare
Ga0059261_2019 +0.5 2.6 Uncharacterized protein conserved in bacteria compare
Ga0059261_1209 +0.5 3.0 HupE / UreJ protein compare
Ga0059261_2018 +0.5 3.7 hypothetical protein compare
Ga0059261_0059 +0.5 1.3 Stress-induced morphogen (activity unknown) compare
Ga0059261_1261 +0.5 1.3 hypothetical protein compare
Ga0059261_0304 +0.5 0.9 Bacterioferritin-associated ferredoxin compare
Ga0059261_2020 +0.5 3.9 Glycosyltransferase compare
Ga0059261_0220 +0.5 3.2 L-serine dehydratase, iron-sulfur-dependent, single chain form compare
Ga0059261_3332 +0.5 2.2 Predicted membrane protein compare
Ga0059261_0832 +0.5 3.7 Predicted permease compare
Ga0059261_0493 +0.5 1.0 hypothetical protein compare
Ga0059261_1915 +0.4 2.5 transcriptional regulator, MucR family compare
Ga0059261_1791 +0.4 0.9 hypothetical protein compare
Ga0059261_3964 +0.4 3.6 Imidazolonepropionase (EC 3.5.2.7) (from data) compare
Ga0059261_0252 +0.4 1.5 SpoIIAA-like compare
Ga0059261_1951 +0.4 1.9 NADPH-glutathione reductase (EC 1.8.1.7) compare
Ga0059261_2188 +0.4 1.4 Uncharacterized conserved protein compare
Ga0059261_3963 +0.4 3.1 Histidine ammonia-lyase (EC 4.3.1.3) (from data) compare
Ga0059261_1652 +0.4 0.9 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily compare
Ga0059261_1597 +0.4 2.8 hypothetical protein compare
Ga0059261_2935 +0.4 2.5 hypothetical protein compare
Ga0059261_0898 +0.4 1.6 Membrane protein implicated in regulation of membrane protease activity compare
Ga0059261_0579 +0.4 3.3 Neutral trehalase compare
Ga0059261_3838 +0.4 1.8 Hemerythrin HHE cation binding domain compare
Ga0059261_1914 +0.4 1.6 Acetyltransferases compare
Ga0059261_0848 +0.4 2.7 transcriptional regulator, TetR family compare
Ga0059261_0354 +0.4 1.5 6-phosphogluconate dehydratase (EC 4.2.1.12) compare
Ga0059261_2187 +0.4 2.7 Cell Wall Hydrolase compare
Ga0059261_0472 +0.4 1.6 Predicted metal-binding protein compare
Ga0059261_3604 +0.4 1.6 Uncharacterized protein conserved in bacteria compare
Ga0059261_2259 +0.4 2.2 hypothetical protein compare
Ga0059261_3971 +0.4 1.2 Uncharacterized protein conserved in bacteria compare
Ga0059261_1181 +0.4 1.5 hypothetical protein compare
Ga0059261_3317 +0.4 3.1 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs compare
Ga0059261_2496 +0.4 1.8 Hemerythrin HHE cation binding domain compare
Ga0059261_4134 +0.4 1.4 tRNA compare
Ga0059261_0983 +0.4 3.4 TonB dependent receptor/TonB-dependent Receptor Plug Domain compare
Ga0059261_2345 +0.4 2.6 hypothetical protein compare
Ga0059261_0244 +0.4 1.3 FOG: CheY-like receiver compare
Ga0059261_2683 +0.4 2.1 Protein of unknown function (DUF3572) compare
Ga0059261_3879 +0.4 1.7 outer membrane autotransporter barrel domain compare
Ga0059261_4214 +0.4 1.2 Enoyl-CoA hydratase/carnithine racemase compare
Ga0059261_1049 +0.4 1.9 PEP-CTERM protein-sorting domain compare
Ga0059261_2478 +0.4 1.6 Uncharacterized conserved protein compare
Ga0059261_1713 +0.4 2.1 hypothetical protein compare
Ga0059261_3834 +0.4 1.9 Molecular chaperone (small heat shock protein) compare
Ga0059261_2215 +0.4 1.1 Thiamine monophosphate synthase compare
Ga0059261_3696 +0.4 1.9 hypothetical protein compare
Ga0059261_0781 +0.4 1.0 hypothetical protein compare
Ga0059261_1587 +0.3 2.0 hypothetical protein compare
Ga0059261_4022 +0.3 2.6 Signal transduction histidine kinase compare
Ga0059261_3920 +0.3 1.8 phosphonoacetaldehyde hydrolase (EC 3.11.1.1) compare
Ga0059261_1196 +0.3 1.4 hypothetical protein compare
Ga0059261_1860 +0.3 0.7 Transposase compare
Ga0059261_0609 +0.3 1.6 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family compare
Ga0059261_1207 +0.3 2.2 Predicted acyltransferases compare
Ga0059261_2044 +0.3 2.4 peptide chain release factor 3 compare
Ga0059261_2755 +0.3 1.5 16S rRNA (cytidine(1402)-2'-O)-methyltransferase compare
Ga0059261_3025 +0.3 1.6 Methylase involved in ubiquinone/menaquinone biosynthesis compare
Ga0059261_1499 +0.3 1.5 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Ga0059261_0035 +0.3 0.8 Uncharacterized protein conserved in bacteria compare
Ga0059261_1211 +0.3 2.2 HlyD family secretion protein compare
Ga0059261_3327 +0.3 1.6 hypothetical protein compare
Ga0059261_3056 +0.3 1.2 Protein of unknown function (DUF2958) compare
Ga0059261_3266 +0.3 2.9 ribonuclease R compare
Ga0059261_3602 +0.3 1.4 Glutaredoxin, GrxC family compare
Ga0059261_0626 +0.3 1.5 Fructose-2,6-bisphosphatase compare
Ga0059261_2471 +0.3 0.6 hypothetical protein compare
Ga0059261_0199 +0.3 1.3 hypothetical protein compare
Ga0059261_1210 +0.3 2.6 heavy metal efflux pump, CzcA family compare
Ga0059261_1596 +0.3 0.7 CBS domain compare
Ga0059261_0038 +0.3 1.3 Transcriptional regulators compare
Ga0059261_3346 +0.3 1.8 hypothetical protein compare
Ga0059261_0685 +0.3 0.7 pyruvate kinase compare
Ga0059261_0655 +0.3 1.9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase/Hpt domain/CheW-like domain/Signal transducing histidine kinase, homodimeric domain compare
Ga0059261_1366 +0.3 2.1 lipid kinase, YegS/Rv2252/BmrU family compare
Ga0059261_3301 +0.3 1.3 Cyanate permease compare
Ga0059261_1461 +0.3 1.9 Metal-dependent hydrolase compare
Ga0059261_1730 +0.3 1.2 Surface presentation of antigens (SPOA) compare
Ga0059261_3436 +0.3 2.3 alkylhydroperoxidase AhpD family core domain compare
Ga0059261_0334 +0.3 2.0 hypothetical protein compare
Ga0059261_0209 +0.3 2.6 His Kinase A (phospho-acceptor) domain/Response regulator receiver domain/Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase compare
Ga0059261_1577 +0.3 2.7 L-glutamine and L-histidine transporter (from data) compare
Ga0059261_2583 +0.3 2.0 Uncharacterized conserved protein (DUF2285) compare
Ga0059261_1259 +0.3 1.3 Ribbon-helix-helix domain compare
Ga0059261_2731 +0.3 1.1 transcriptional regulator, AraC family compare
Ga0059261_0622 +0.3 1.8 ABC-type Fe3+-hydroxamate transport system, periplasmic component compare
Ga0059261_3058 +0.3 1.3 hypothetical protein compare
Ga0059261_0770 +0.3 0.7 hypothetical protein compare
Ga0059261_2076 +0.3 0.8 hypothetical protein compare
Ga0059261_0062 +0.3 1.3 hypothetical protein compare
Ga0059261_3885 +0.3 0.8 K+-transporting ATPase, C subunit compare
Ga0059261_1521 +0.3 1.4 diguanylate cyclase (GGDEF) domain compare
Ga0059261_0388 +0.3 1.5 Type IV secretory pathway, VirB2 components (pilins) compare
Ga0059261_1115 +0.3 0.7 Chemotaxis protein; stimulates methylation of MCP proteins compare
Ga0059261_3027 +0.3 1.3 Predicted transcriptional regulators compare
Ga0059261_4181 +0.3 1.9 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family compare
Ga0059261_4094 +0.3 1.8 Sulfotransferase domain compare
Ga0059261_3906 +0.3 1.8 Transcriptional regulator compare
Ga0059261_3383 +0.3 2.0 transcriptional regulator, TetR family compare
Ga0059261_3526 +0.3 2.1 hemimethylated DNA binding domain compare
Ga0059261_2978 +0.3 1.2 Transcriptional regulators compare
Ga0059261_3706 +0.3 1.3 RF-1 domain compare
Ga0059261_2231 +0.3 1.5 Uncharacterized conserved protein compare
Ga0059261_2663 +0.3 0.6 Domain of unknown function (DUF718) compare
Ga0059261_2897 +0.3 1.1 hypothetical protein compare
Ga0059261_2850 +0.3 1.8 Uncharacterized protein, possibly involved in aromatic compounds catabolism compare
Ga0059261_3207 +0.3 1.5 Disulfide bond chaperones of the HSP33 family compare
Ga0059261_1774 +0.3 0.8 hypothetical protein compare
Ga0059261_3009 +0.3 1.4 Acetyltransferase (GNAT) domain compare
Ga0059261_2783 +0.3 2.1 hypothetical protein compare
Ga0059261_2691 +0.3 1.1 Zn-dependent dipeptidase, microsomal dipeptidase homolog compare
Ga0059261_0625 +0.3 1.0 nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) compare
Ga0059261_0268 +0.3 1.4 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily compare
Ga0059261_2052 +0.3 1.2 siroheme synthase, N-terminal domain compare
Ga0059261_1077 +0.3 1.3 STAS domain compare
Ga0059261_0242 +0.3 0.8 hypothetical protein compare
Ga0059261_3620 +0.3 0.6 molybdenum cofactor biosynthesis protein A, bacterial compare
Ga0059261_0906 +0.3 1.2 Uncharacterized conserved protein compare
Ga0059261_2093 +0.3 1.6 flagellar basal-body rod protein FlgF compare
Ga0059261_3992 +0.3 0.9 Uncharacterized protein conserved in bacteria compare
Ga0059261_4051 +0.3 1.0 Transcriptional regulator compare
Ga0059261_1292 +0.3 0.8 hypothetical protein compare
Ga0059261_3784 +0.3 2.1 DNA mismatch repair protein MutS compare
Ga0059261_3847 +0.3 2.2 Beta-glucosidase-related glycosidases compare
Ga0059261_0827 +0.3 0.8 hypothetical protein compare
Ga0059261_3546 +0.3 1.7 hypothetical protein compare
Ga0059261_2086 +0.3 0.6 SAF-like compare
Ga0059261_2448 +0.3 0.5 DNA protecting protein DprA compare
Ga0059261_1242 +0.3 1.4 transcriptional regulator, MerR family compare
Ga0059261_4217 +0.3 0.7 hypothetical protein compare
Ga0059261_3603 +0.3 1.6 Predicted amidohydrolase compare
Ga0059261_4155 +0.3 1.6 Uncharacterized protein conserved in bacteria compare
Ga0059261_2744 +0.3 2.1 CDP-alcohol phosphatidyltransferase compare
Ga0059261_3328 +0.3 2.2 Uncharacterized iron-regulated membrane protein compare
Ga0059261_2028 +0.3 1.6 L-threonine aldolase (EC 4.1.2.5) compare
Ga0059261_3441 +0.3 0.8 hypothetical protein compare
Ga0059261_3326 +0.3 2.3 Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid compare
Ga0059261_1228 +0.3 1.7 uncharacterized domain 1 compare
Ga0059261_2361 +0.3 1.4 Staphylococcal nuclease homologue compare
Ga0059261_3305 +0.3 1.5 Uncharacterized conserved protein compare
Ga0059261_3634 +0.3 1.1 Predicted membrane protein compare
Ga0059261_3664 +0.2 1.4 hypothetical protein compare
Ga0059261_0592 +0.2 0.9 hypothetical protein compare
Ga0059261_1129 +0.2 1.7 hypothetical protein compare
Ga0059261_2171 +0.2 1.7 Uncharacterized protein, similar to the N-terminal domain of Lon protease compare
Ga0059261_1992 +0.2 1.7 Short-chain alcohol dehydrogenase of unknown specificity compare
Ga0059261_2658 +0.2 1.0 Transcriptional regulators compare
Ga0059261_2035 +0.2 1.8 Histidinol-phosphatase [alternative form] (EC 3.1.3.15) (from data) compare
Ga0059261_4171 +0.2 1.2 redox-sensitive transcriptional activator SoxR compare
Ga0059261_1443 +0.2 1.9 Hemolysins and related proteins containing CBS domains compare
Ga0059261_3174 +0.2 1.3 EF hand compare
Ga0059261_1897 +0.2 1.6 Transcriptional regulators compare
Ga0059261_0270 +0.2 1.7 Uncharacterized protein conserved in bacteria compare
Ga0059261_0305 +0.2 0.9 bacterioferritin compare
Ga0059261_0586 +0.2 1.0 hypothetical protein compare
Ga0059261_2349 +0.2 1.0 hypothetical protein compare
Ga0059261_4184 +0.2 1.2 exosortase A system-associated hydrolase 1 compare
Ga0059261_1212 +0.2 1.6 Outer membrane protein compare
Ga0059261_1446 +0.2 1.3 hypothetical protein compare
Ga0059261_3667 +0.2 1.6 molybdate ABC transporter, permease protein compare
Ga0059261_3989 +0.2 1.6 biotin synthase (EC 2.8.1.6) compare
Ga0059261_3262 +0.2 1.4 Predicted permeases compare
Ga0059261_4030 +0.2 1.2 glutamate N-acetyltransferase (EC 2.3.1.35) compare
Ga0059261_4015 +0.2 1.5 Putative transcriptional regulator compare
Ga0059261_1852 +0.2 1.2 hypothetical protein compare
Ga0059261_2886 +0.2 0.9 electron transfer flavoprotein beta subunit compare
Ga0059261_0975 +0.2 1.4 Flp pilus assembly protein, ATPase CpaF compare
Ga0059261_0594 +0.2 1.3 RND family efflux transporter, MFP subunit compare
Ga0059261_1896 +0.2 1.5 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) (from data) compare
Ga0059261_0836 +0.2 1.8 Beta-lactamase class C and other penicillin binding proteins compare
Ga0059261_2801 +0.2 1.4 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare


Specific Phenotypes

For 1 genes in this experiment

For stress Cobalt chloride hexahydrate in Sphingomonas koreensis DSMZ 15582

For stress Cobalt chloride hexahydrate across organisms