Experiment set3IT086 for Sphingomonas koreensis DSMZ 15582

Compare to:

LB with Nickel (II) chloride hexahydrate 1.5 mM

200 most detrimental genes:

  gene name fitness t score description  
Ga0059261_1380 +1.9 16.0 Membrane protease subunits, stomatin/prohibitin homologs compare
Ga0059261_1381 +1.8 12.1 Membrane protease subunits, stomatin/prohibitin homologs compare
Ga0059261_2471 +1.2 2.4 hypothetical protein compare
Ga0059261_2413 +1.1 3.3 hypothetical protein compare
Ga0059261_0657 +1.1 2.6 Uncharacterized protein conserved in bacteria compare
Ga0059261_4001 +1.0 6.0 NTP pyrophosphohydrolases including oxidative damage repair enzymes compare
Ga0059261_3364 +1.0 9.3 PEP-CTERM/exosortase A-associated glycosyltransferase, Daro_2409 family compare
Ga0059261_0102 +1.0 8.0 endopeptidase La compare
Ga0059261_0493 +1.0 2.7 hypothetical protein compare
Ga0059261_3361 +1.0 8.9 hypothetical protein compare
Ga0059261_2294 +1.0 1.8 Cell division protein compare
Ga0059261_4195 +0.9 7.0 polysaccharide deacetylase family protein, PEP-CTERM locus subfamily compare
Ga0059261_4191 +0.9 6.1 polysaccharide chain length determinant protein, PEP-CTERM locus subfamily compare
Ga0059261_4185 +0.9 2.6 hypothetical protein compare
Ga0059261_4190 +0.9 7.2 Periplasmic protein involved in polysaccharide export compare
Ga0059261_4193 +0.9 8.3 hypothetical protein compare
Ga0059261_3658 +0.9 7.6 hypothetical protein compare
Ga0059261_1569 +0.9 4.4 Response regulator receiver domain compare
Ga0059261_3698 +0.9 7.9 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Ga0059261_3362 +0.9 8.1 Lipid A core - O-antigen ligase and related enzymes compare
Ga0059261_3562 +0.9 3.8 Glycosyltransferase compare
Ga0059261_3659 +0.9 3.8 PqqD family protein, HPr-rel-A system compare
Ga0059261_1361 +0.8 7.2 sugar transferase, PEP-CTERM system associated/exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase compare
Ga0059261_0209 +0.8 7.4 His Kinase A (phospho-acceptor) domain/Response regulator receiver domain/Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase compare
Ga0059261_1490 +0.8 7.1 Glycosyltransferase compare
Ga0059261_3660 +0.8 6.6 HprK-related kinase A compare
Ga0059261_2698 +0.8 6.4 N-acetylmuramoyl-L-alanine amidase compare
Ga0059261_4022 +0.8 6.7 Signal transduction histidine kinase compare
Ga0059261_3661 +0.8 6.4 Uncharacterised nucleotidyltransferase compare
Ga0059261_4197 +0.8 6.6 sugar transferase, PEP-CTERM/EpsH1 system associated compare
Ga0059261_2502 +0.8 4.3 Membrane-bound metallopeptidase compare
Ga0059261_0344 +0.8 3.3 Molecular chaperone (small heat shock protein) compare
Ga0059261_4002 +0.7 4.7 Esterase/lipase compare
Ga0059261_3810 +0.7 3.5 Transcriptional regulators compare
Ga0059261_3365 +0.7 3.1 hypothetical protein compare
Ga0059261_1595 +0.7 6.6 Membrane protein involved in the export of O-antigen and teichoic acid compare
Ga0059261_3188 +0.7 6.3 Acetyltransferase (GNAT) domain compare
Ga0059261_1050 +0.7 2.2 hypothetical protein compare
Ga0059261_0817 +0.7 4.8 GTP-binding protein TypA/BipA compare
Ga0059261_4196 +0.7 6.0 FemAB-related protein, PEP-CTERM system-associated compare
Ga0059261_3403 +0.7 4.9 Uncharacterized protein conserved in bacteria compare
Ga0059261_2980 +0.7 6.3 Outer membrane protein compare
Ga0059261_4184 +0.7 4.4 exosortase A system-associated hydrolase 1 compare
Ga0059261_2227 +0.7 6.1 aminodeoxychorismate synthase, component I, bacterial clade compare
Ga0059261_1409 +0.7 4.2 hypothetical protein compare
Ga0059261_2619 +0.6 5.4 Protein involved in cellulose biosynthesis (CelD) compare
Ga0059261_0685 +0.6 1.5 pyruvate kinase compare
Ga0059261_3400 +0.6 5.2 diguanylate cyclase (GGDEF) domain compare
Ga0059261_2737 +0.6 3.9 UTP--GlnB (protein PII) uridylyltransferase, GlnD compare
Ga0059261_2701 +0.6 5.0 Protein-disulfide isomerase compare
Ga0059261_4194 +0.6 4.7 Type II secretory pathway, component ExeA (predicted ATPase) compare
Ga0059261_4199 +0.6 5.2 asparagine synthase (glutamine-hydrolyzing) compare
Ga0059261_2730 +0.6 1.9 Sortase and related acyltransferases compare
Ga0059261_2188 +0.6 1.7 Uncharacterized conserved protein compare
Ga0059261_2293 +0.6 2.9 cell division ATP-binding protein FtsE compare
Ga0059261_2981 +0.6 5.1 Uncharacterized protein conserved in bacteria compare
Ga0059261_0059 +0.6 1.3 Stress-induced morphogen (activity unknown) compare
Ga0059261_3631 +0.6 4.0 hypothetical protein compare
Ga0059261_4198 +0.6 4.6 exosortase A compare
Ga0059261_2682 +0.5 3.3 Response regulator receiver domain compare
Ga0059261_4122 +0.5 2.1 Gluconate 2-dehydrogenase subunit 3 compare
Ga0059261_0071 +0.5 4.7 Sporulation related domain/Sel1 repeat compare
Ga0059261_0121 +0.5 1.2 Sporulation related domain compare
Ga0059261_1181 +0.5 1.6 hypothetical protein compare
Ga0059261_0040 +0.5 4.6 hypothetical protein compare
Ga0059261_3783 +0.5 3.0 hypothetical protein compare
Ga0059261_1011 +0.5 2.4 S-adenosylmethionine:tRNA ribosyltransferase-isomerase compare
Ga0059261_2504 +0.5 4.0 ribosome silencing factor RsfS/YbeB/iojap compare
Ga0059261_1438 +0.5 3.0 Membrane proteins related to metalloendopeptidases compare
Ga0059261_1527 +0.5 1.0 hypothetical protein compare
Ga0059261_1939 +0.5 1.1 putative phosphoesterase compare
Ga0059261_1260 +0.5 3.9 cobaltochelatase CobT subunit (EC 6.6.1.2) compare
Ga0059261_2187 +0.5 3.5 Cell Wall Hydrolase compare
Ga0059261_1914 +0.5 1.3 Acetyltransferases compare
Ga0059261_3287 +0.5 3.6 Topoisomerase IB compare
Ga0059261_1262 +0.5 4.1 cobaltochelatase CobS subunit (EC 6.6.1.2) compare
Ga0059261_3759 +0.5 1.8 hypothetical protein compare
Ga0059261_1881 +0.5 2.4 Predicted membrane protein compare
Ga0059261_0141 +0.5 2.1 transcriptional regulator, LysR family compare
Ga0059261_1197 +0.5 1.8 hypothetical protein compare
Ga0059261_0745 +0.5 1.8 Uncharacterized membrane protein, required for colicin V production compare
Ga0059261_3401 +0.5 3.3 Domain of unknown function (DUF4154) compare
Ga0059261_1364 +0.5 3.8 TPR repeat/Tetratricopeptide repeat compare
Ga0059261_0266 +0.4 1.3 hypothetical protein compare
Ga0059261_1756 +0.4 0.9 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes compare
Ga0059261_0161 +0.4 1.6 molybdopterin converting factor, subunit 1, non-archaeal compare
Ga0059261_3885 +0.4 1.3 K+-transporting ATPase, C subunit compare
Ga0059261_1878 +0.4 2.3 RND family efflux transporter, MFP subunit compare
Ga0059261_3807 +0.4 2.3 Uncharacterized conserved protein compare
Ga0059261_2570 +0.4 1.8 Type IV secretory pathway, TrbD component compare
Ga0059261_1573 +0.4 2.5 hypothetical protein compare
Ga0059261_3569 +0.4 1.4 chaperone protein DnaJ compare
Ga0059261_2987 +0.4 1.3 hypothetical protein compare
Ga0059261_1031 +0.4 3.4 hypothetical protein compare
Ga0059261_1791 +0.4 1.2 hypothetical protein compare
Ga0059261_3237 +0.4 2.1 hypothetical protein compare
Ga0059261_1169 +0.4 1.6 hypothetical protein compare
Ga0059261_3693 +0.4 3.0 Putative arginyl-tRNA:protein arginylyltransferase compare
Ga0059261_1092 +0.4 1.4 flagellar motor switch protein FliN compare
Ga0059261_3630 +0.4 2.9 phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Ga0059261_1759 +0.4 1.6 Phosphoadenosine phosphosulfate reductase family compare
Ga0059261_1912 +0.4 1.4 Nitroreductase compare
Ga0059261_3407 +0.4 2.8 Superfamily II DNA and RNA helicases compare
Ga0059261_2378 +0.4 1.3 phage virion morphogenesis (putative tail completion) protein compare
Ga0059261_3368 +0.4 1.8 Predicted transcriptional regulator compare
Ga0059261_0993 +0.4 1.1 Methylase involved in ubiquinone/menaquinone biosynthesis compare
Ga0059261_3006 +0.4 2.1 hypothetical protein compare
Ga0059261_2271 +0.4 3.0 branched-chain alpha-keto acid dehydrogenase E2 component (EC 2.3.1.168) compare
Ga0059261_4217 +0.4 1.2 hypothetical protein compare
Ga0059261_3666 +0.4 2.1 molybdenum ABC transporter, periplasmic molybdate-binding protein compare
Ga0059261_2662 +0.4 3.1 Transcriptional regulators compare
Ga0059261_3594 +0.4 2.6 hypothetical protein compare
Ga0059261_1587 +0.4 2.2 hypothetical protein compare
Ga0059261_2020 +0.4 3.0 Glycosyltransferase compare
Ga0059261_3491 +0.4 2.4 hypothetical protein compare
Ga0059261_0850 +0.4 1.3 hypothetical protein compare
Ga0059261_3056 +0.4 1.5 Protein of unknown function (DUF2958) compare
Ga0059261_3638 +0.4 1.0 Predicted integral membrane protein (DUF2282) compare
Ga0059261_1985 +0.4 1.2 transcriptional regulator NrdR compare
Ga0059261_2215 +0.4 0.8 Thiamine monophosphate synthase compare
Ga0059261_3027 +0.3 1.7 Predicted transcriptional regulators compare
Ga0059261_1999 +0.3 2.3 threonine synthase compare
Ga0059261_2593 +0.3 0.9 hypothetical protein compare
Ga0059261_4038 +0.3 3.2 Predicted periplasmic ligand-binding sensor domain compare
Ga0059261_1335 +0.3 1.7 Predicted ATPase compare
Ga0059261_1183 +0.3 1.6 Protein of unknown function (DUF2958) compare
Ga0059261_2044 +0.3 2.4 peptide chain release factor 3 compare
Ga0059261_2448 +0.3 1.0 DNA protecting protein DprA compare
Ga0059261_1713 +0.3 1.3 hypothetical protein compare
Ga0059261_1057 +0.3 1.8 hypothetical protein compare
Ga0059261_0451 +0.3 1.3 hypothetical protein compare
Ga0059261_1360 +0.3 2.5 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase compare
Ga0059261_3801 +0.3 1.4 Phosphate/sulphate permeases compare
Ga0059261_2948 +0.3 1.5 Putative copper export protein compare
Ga0059261_1538 +0.3 1.1 Predicted transcriptional regulators compare
Ga0059261_0891 +0.3 1.2 hypothetical protein compare
Ga0059261_3526 +0.3 2.4 hemimethylated DNA binding domain compare
Ga0059261_0816 +0.3 1.1 hypothetical protein compare
Ga0059261_0734 +0.3 2.0 RNA compare
Ga0059261_1833 +0.3 2.2 hypothetical protein compare
Ga0059261_2715 +0.3 2.0 hypothetical protein compare
Ga0059261_3784 +0.3 2.6 DNA mismatch repair protein MutS compare
Ga0059261_1174 +0.3 1.3 Putative transposase of IS4/5 family (DUF4096) compare
Ga0059261_3670 +0.3 1.6 tRNA compare
Ga0059261_3121 +0.3 2.0 asparagine synthase (glutamine-hydrolyzing) compare
Ga0059261_3359 +0.3 0.9 Zn-dependent hydrolases, including glyoxylases compare
Ga0059261_0624 +0.3 2.0 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components compare
Ga0059261_1398 +0.3 1.7 Sulfite oxidase and related enzymes compare
Ga0059261_1261 +0.3 1.3 hypothetical protein compare
Ga0059261_1986 +0.3 1.9 Glycine/serine hydroxymethyltransferase compare
Ga0059261_4032 +0.3 1.7 Sensors of blue-light using FAD compare
Ga0059261_0312 +0.3 1.6 hypothetical protein compare
Ga0059261_0533 +0.3 1.5 FecR family protein compare
Ga0059261_0907 +0.3 1.6 Predicted transcriptional regulators compare
Ga0059261_1545 +0.3 1.5 Fe2+/Zn2+ uptake regulation proteins compare
Ga0059261_3833 +0.3 0.8 hypothetical protein compare
Ga0059261_2583 +0.3 1.7 Uncharacterized conserved protein (DUF2285) compare
Ga0059261_2273 +0.3 2.5 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit compare
Ga0059261_2018 +0.3 2.1 hypothetical protein compare
Ga0059261_1596 +0.3 0.9 CBS domain compare
Ga0059261_3556 +0.3 1.0 transcriptional regulator, TetR family compare
Ga0059261_3609 +0.3 1.3 Protein of unknown function (DUF2945) compare
Ga0059261_0777 +0.3 1.9 FecR family protein compare
Ga0059261_4224 +0.3 0.6 hypothetical protein compare
Ga0059261_0083 +0.3 0.5 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B (EC 6.3.5.-) compare
Ga0059261_0405 +0.3 1.5 Uncharacterized conserved protein compare
Ga0059261_0069 +0.3 1.5 tRNA dimethylallyltransferase compare
Ga0059261_1505 +0.3 1.6 Lyzozyme M1 (1,4-beta-N-acetylmuramidase) compare
Ga0059261_0153 +0.3 1.2 Serine acetyltransferase compare
Ga0059261_3552 +0.3 1.8 hypothetical protein compare
Ga0059261_1285 +0.3 1.9 Uncharacterized conserved protein compare
Ga0059261_1119 +0.3 0.8 Chemotaxis signal transduction protein compare
Ga0059261_2345 +0.3 1.7 hypothetical protein compare
Ga0059261_2957 +0.3 1.9 Signal transduction histidine kinase compare
Ga0059261_3834 +0.3 1.4 Molecular chaperone (small heat shock protein) compare
Ga0059261_1190 +0.3 1.3 hypothetical protein compare
Ga0059261_2568 +0.3 1.3 P-type conjugative transfer protein TrbJ compare
Ga0059261_3862 +0.3 1.3 Multidrug resistance efflux pump compare
Ga0059261_1135 +0.3 1.8 Flagellin and related hook-associated proteins compare
Ga0059261_3193 +0.3 2.3 Dolichyl-phosphate-mannose-protein mannosyltransferase compare
Ga0059261_3366 +0.3 0.9 hypothetical protein compare
Ga0059261_0133 +0.3 0.8 GTP-binding protein HflX compare
Ga0059261_2071 +0.2 1.3 flagellar motor switch protein FliG compare
Ga0059261_3100 +0.2 1.9 Sugar transferases involved in lipopolysaccharide synthesis compare
Ga0059261_0227 +0.2 1.0 hypothetical protein compare
Ga0059261_0389 +0.2 1.3 P-type conjugative transfer ATPase TrbB compare
Ga0059261_2466 +0.2 2.0 DnaJ domain/DnaJ C terminal domain compare
Ga0059261_3985 +0.2 1.6 methylmalonyl-CoA epimerase (EC 5.1.99.1) compare
Ga0059261_3346 +0.2 1.6 hypothetical protein compare
Ga0059261_1333 +0.2 1.7 Zn-dependent hydrolases, including glyoxylases compare
Ga0059261_0818 +0.2 1.9 OmpA family compare
Ga0059261_1464 +0.2 1.7 Aspartyl/Asparaginyl beta-hydroxylase compare
Ga0059261_3948 +0.2 0.8 type II secretion system protein H compare
Ga0059261_1016 +0.2 0.9 Cupin domain compare
Ga0059261_1109 +0.2 1.4 Flagellar biosynthesis protein, FliO compare
Ga0059261_1862 +0.2 1.1 Transposase compare
Ga0059261_3620 +0.2 0.8 molybdenum cofactor biosynthesis protein A, bacterial compare
Ga0059261_1574 +0.2 1.1 Superfamily II DNA and RNA helicases compare
Ga0059261_3641 +0.2 1.3 Uncharacterized conserved protein compare
Ga0059261_3174 +0.2 1.2 EF hand compare


Specific Phenotypes

For 4 genes in this experiment

For stress Nickel (II) chloride hexahydrate in Sphingomonas koreensis DSMZ 15582

For stress Nickel (II) chloride hexahydrate across organisms