Experiment set3IT083 for Pseudomonas fluorescens FW300-N2E2

Compare to:

LB with copper (II) chloride dihydrate 3 mM

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_2129 -8.2 -5.4 Predicted dye-decolorizing peroxidase (DyP), YfeX-like subgroup compare
Pf6N2E2_4353 -7.8 -7.6 Hydrogen peroxide-inducible genes activator compare
Pf6N2E2_4071 -7.6 -5.3 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_445 -6.8 -4.7 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) compare
Pf6N2E2_2267 -6.3 -6.1 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) conserved
Pf6N2E2_3948 -6.1 -15.3 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_4072 -6.1 -4.2 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_2753 -5.9 -4.1 HtrA protease/chaperone protein compare
Pf6N2E2_3487 -5.5 -12.6 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_3488 -5.5 -7.7 Cu(I)-responsive transcriptional regulator conserved
Pf6N2E2_4352 -5.5 -3.8 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_3941 -5.4 -5.3 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_2825 -5.3 -3.7 RND efflux system, outer membrane lipoprotein CmeC compare
Pf6N2E2_5027 -5.3 -13.0 AMP nucleosidase (EC 3.2.2.4) compare
Pf6N2E2_3791 -5.3 -13.2 Glucans biosynthesis glucosyltransferase H (EC 2.4.1.-) compare
Pf6N2E2_3282 -5.3 -6.0 FIG005080: Possible exported protein compare
Pf6N2E2_5150 -5.3 -9.1 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_4075 -5.3 -8.0 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) compare
Pf6N2E2_5551 -5.2 -9.9 Copper resistance protein B conserved
Pf6N2E2_5014 -5.1 -1.6 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_760 -5.1 -12.0 Na+/H+ antiporter NhaB compare
Pf6N2E2_5552 -5.1 -20.7 Multicopper oxidase conserved
Pf6N2E2_5723 -5.0 -16.0 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_4369 -4.9 -3.4 Exodeoxyribonuclease III (EC 3.1.11.2) compare
Pf6N2E2_5006 -4.8 -10.2 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_2274 -4.5 -9.0 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_4416 -4.5 -4.5 Tyrosine recombinase XerC compare
Pf6N2E2_2266 -4.5 -2.8 Copper-sensing two-component system response regulator CusR compare
Pf6N2E2_2075 -4.5 -8.7 Peptidase, U7 family compare
Pf6N2E2_1626 -4.2 -8.8 Putative ATP-binding component of a transport system compare
Pf6N2E2_3612 -4.1 -3.6 HflK protein compare
Pf6N2E2_3792 -4.1 -6.3 Glucans biosynthesis protein G precursor compare
Pf6N2E2_2824 -4.0 -11.9 RND efflux system, inner membrane transporter CmeB compare
Pf6N2E2_4187 -3.9 -6.5 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_5178 -3.8 -3.3 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) compare
Pf6N2E2_5677 -3.7 -1.9 Carbon storage regulator compare
Pf6N2E2_5160 -3.5 -2.4 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_2823 -3.5 -5.6 Multidrug efflux RND membrane fusion protein MexC compare
Pf6N2E2_5430 -3.5 -9.1 Transglycosylase, Slt family compare
Pf6N2E2_2258 -3.4 -8.1 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_3667 -3.4 -2.4 Heptose kinase WapQ, eukaryotic type compare
Pf6N2E2_3942 -3.3 -13.8 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
Pf6N2E2_5527 -3.3 -3.2 Cold shock protein CspC compare
Pf6N2E2_1636 -3.3 -11.0 Ferrichrome-iron receptor compare
Pf6N2E2_2636 -3.2 -3.5 FIG027190: Putative transmembrane protein compare
Pf6N2E2_3607 -3.2 -6.8 3'-to-5' exoribonuclease RNase R compare
Pf6N2E2_5321 -3.1 -11.7 Heme O synthase, protoheme IX farnesyltransferase (EC 2.5.1.-) COX10-CtaB compare
Pf6N2E2_2384 -3.1 -5.4 CmpX compare
Pf6N2E2_3460 -3.1 -2.5 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_4272 -3.0 -5.2 putative membrane protein compare
Pf6N2E2_2938 -3.0 -4.1 Outer membrane lipoprotein compare
Pf6N2E2_3786 -3.0 -3.2 Twin-arginine translocation protein TatC compare
Pf6N2E2_5328 -2.9 -3.1 FIG00958649: hypothetical protein compare
Pf6N2E2_4453 -2.9 -14.6 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_5319 -2.9 -9.1 Cytochrome O ubiquinol oxidase subunit III (EC 1.10.3.-) compare
Pf6N2E2_3908 -2.9 -7.2 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_5943 -2.9 -2.7 hypothetical protein compare
Pf6N2E2_5320 -2.7 -6.7 Cytochrome O ubiquinol oxidase subunit IV (EC 1.10.3.-) compare
Pf6N2E2_4162 -2.7 -2.7 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_1087 -2.7 -10.2 Iron siderophore sensor protein compare
Pf6N2E2_4074 -2.6 -9.7 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) compare
Pf6N2E2_144 -2.6 -13.1 Uncharacterized protein YtfM precursor compare
Pf6N2E2_2574 -2.6 -1.8 Flagellar synthesis regulator FleN compare
Pf6N2E2_4611 -2.5 -4.4 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_145 -2.5 -6.8 putative exported protein compare
Pf6N2E2_5111 -2.5 -2.2 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf6N2E2_3373 -2.4 -2.5 Outer membrane lipoprotein SmpA, a component of the essential YaeT outer-membrane protein assembly complex compare
Pf6N2E2_600 -2.3 -2.4 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases compare
Pf6N2E2_4077 -2.3 -2.4 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf6N2E2_5318 -2.3 -15.5 Cytochrome O ubiquinol oxidase subunit I (EC 1.10.3.-) compare
Pf6N2E2_1625 -2.3 -3.2 Ferric reductase (1.6.99.14) compare
Pf6N2E2_156 -2.3 -1.6 Carbon storage regulator compare
Pf6N2E2_4889 -2.2 -5.3 Putative transport protein compare
Pf6N2E2_3264 -2.2 -4.2 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_4678 -2.1 -1.1 hypothetical protein compare
Pf6N2E2_3672 -2.1 -8.6 Glutamate-ammonia-ligase adenylyltransferase (EC 2.7.7.42) compare
Pf6N2E2_4599 -2.1 -2.7 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) compare
Pf6N2E2_623 -2.1 -1.4 FIG00954674: hypothetical protein compare
Pf6N2E2_625 -2.1 -4.6 MoxR-like ATPase in aerotolerance operon compare
Pf6N2E2_2396 -2.1 -3.7 Sensor histidine kinase compare
Pf6N2E2_4091 -2.1 -10.8 Oligopeptidase A (EC 3.4.24.70) compare
Pf6N2E2_4641 -2.0 -5.1 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf6N2E2_3778 -2.0 -4.2 FIG00954300: hypothetical protein compare
Pf6N2E2_5317 -2.0 -11.1 Cytochrome O ubiquinol oxidase subunit II (EC 1.10.3.-) compare
Pf6N2E2_3024 -2.0 -2.1 Phage tail fibers compare
Pf6N2E2_4584 -2.0 -2.4 Cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1) compare
Pf6N2E2_5124 -1.9 -5.4 FIG00953647: hypothetical protein conserved
Pf6N2E2_601 -1.9 -3.9 GlpG protein (membrane protein of glp regulon) compare
Pf6N2E2_3151 -1.9 -3.6 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_622 -1.9 -4.9 BatA (Bacteroides aerotolerance operon) compare
Pf6N2E2_4451 -1.9 -5.9 FIG139438: lipoprotein B compare
Pf6N2E2_3666 -1.9 -2.8 InaA protein compare
Pf6N2E2_2080 -1.9 -1.4 hypothetical protein compare
Pf6N2E2_3257 -1.8 -2.5 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_309 -1.8 -1.5 FIG00957702: hypothetical protein compare
Pf6N2E2_2465 -1.8 -5.8 Cys regulon transcriptional activator CysB compare
Pf6N2E2_624 -1.8 -4.7 hypothetical protein PA3071 compare
Pf6N2E2_503 -1.8 -3.3 sensor histidine kinase compare
Pf6N2E2_5155 -1.7 -2.6 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_621 -1.7 -5.4 TPR domain protein in aerotolerance operon compare
Pf6N2E2_2397 -1.7 -2.5 Two-component system response regulator QseB compare
Pf6N2E2_5316 -1.7 -1.7 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_3351 -1.7 -3.7 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf6N2E2_3830 -1.7 -2.2 Glutaredoxin 3 (Grx3) compare
Pf6N2E2_4218 -1.7 -7.0 hypothetical protein compare
Pf6N2E2_1705 -1.6 -1.6 Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) compare
Pf6N2E2_3947 -1.6 -1.6 Cd(II)/Pb(II)-responsive transcriptional regulator compare
Pf6N2E2_620 -1.6 -6.8 BatD compare
Pf6N2E2_1635 -1.6 -2.7 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components compare
Pf6N2E2_3429 -1.6 -4.7 hypothetical protein compare
Pf6N2E2_2369 -1.6 -3.6 Flagellum-specific ATP synthase FliI compare
Pf6N2E2_3060 -1.6 -3.2 Outer membrane protein H precursor compare
Pf6N2E2_5841 -1.5 -1.2 GlcG protein compare
Pf6N2E2_5544 -1.5 -5.1 TPR repeat containing exported protein; Putative periplasmic protein contains a protein prenylyltransferase domain compare
Pf6N2E2_4963 -1.5 -1.8 Homoserine dehydrogenase (EC 1.1.1.3) compare
Pf6N2E2_2265 -1.5 -1.1 Copper tolerance protein compare
Pf6N2E2_5679 -1.5 -4.3 hypothetical protein compare
Pf6N2E2_1082 -1.5 -2.5 CopG protein compare
Pf6N2E2_3132 -1.5 -2.1 FIG00954548: hypothetical protein compare
Pf6N2E2_471 -1.5 -7.4 putative metalloprotease compare
Pf6N2E2_4364 -1.5 -1.4 Protein YicC compare
Pf6N2E2_4661 -1.5 -3.3 KluA regulatory protein compare
Pf6N2E2_1718 -1.5 -2.9 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) compare
Pf6N2E2_3271 -1.5 -2.1 Phosphocarrier protein, nitrogen regulation associated compare
Pf6N2E2_3661 -1.4 -3.6 hypothetical protein compare
Pf6N2E2_3611 -1.4 -1.5 HflC protein compare
Pf6N2E2_1173 -1.4 -2.0 hypothetical protein compare
Pf6N2E2_3300 -1.4 -2.9 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf6N2E2_1545 -1.4 -3.9 N-carbamoylputrescine amidase (EC 3.5.1.53) compare
Pf6N2E2_5727 -1.4 -3.5 FIG00955360: hypothetical protein compare
Pf6N2E2_70 -1.4 -2.6 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_5668 -1.4 -2.8 Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71) compare
Pf6N2E2_4432 -1.4 -3.8 Uroporphyrinogen-III synthase (EC 4.2.1.75) compare
Pf6N2E2_1792 -1.4 -3.2 Hydroxypyruvate isomerase (EC 5.3.1.22) compare
Pf6N2E2_4359 -1.3 -2.7 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_2261 -1.3 -3.7 VacJ-like lipoprotein precursor compare
Pf6N2E2_5103 -1.3 -0.8 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_5669 -1.3 -5.1 Succinylarginine dihydrolase (EC 3.5.3.23) compare
Pf6N2E2_4766 -1.3 -8.2 Acyl-CoA dehydrogenase (EC 1.3.8.7) compare
Pf6N2E2_37 -1.3 -2.1 6-carboxytetrahydropterin synthase (EC 4.1.2.50) @ Queuosine biosynthesis QueD, PTPS-I compare
Pf6N2E2_3260 -1.3 -3.2 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_2010 -1.3 -1.1 hypothetical protein compare
Pf6N2E2_4433 -1.3 -4.1 Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) compare
Pf6N2E2_2180 -1.2 -2.0 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_5746 -1.2 -2.2 Cobalamin synthase compare
Pf6N2E2_1239 -1.2 -3.7 Putative TEGT family carrier/transport protein compare
Pf6N2E2_5508 -1.2 -1.3 Formyltetrahydrofolate deformylase (EC 3.5.1.10) compare
Pf6N2E2_2750 -1.2 -3.9 Putative permease PerM (= YfgO) compare
Pf6N2E2_4488 -1.2 -2.4 Ribonucleotide reductase, alpha subunit compare
Pf6N2E2_2181 -1.2 -1.5 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_1634 -1.2 -2.4 ABC-type Fe3+-siderophore transport system, permease component compare
Pf6N2E2_3834 -1.2 -3.9 Lipoprotein NlpD compare
Pf6N2E2_5420 -1.2 -3.3 Cytosol aminopeptidase PepA (EC 3.4.11.1) compare
Pf6N2E2_786 -1.2 -1.7 Type-1 fimbrial protein, A chain precursor compare
Pf6N2E2_1534 -1.1 -1.7 Probable transmembrane protein compare
Pf6N2E2_3770 -1.1 -1.2 ATP-dependent hsl protease ATP-binding subunit HslU compare
Pf6N2E2_5499 -1.1 -0.9 hypothetical protein compare
Pf6N2E2_1059 -1.1 -6.2 Phosphoglucomutase (EC 5.4.2.2) conserved
Pf6N2E2_5658 -1.1 -3.7 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit compare
Pf6N2E2_3270 -1.1 -3.5 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
Pf6N2E2_1113 -1.1 -1.0 Transcriptional regulator, TetR family compare
Pf6N2E2_2438 -1.1 -1.3 hypothetical protein compare
Pf6N2E2_2352 -1.1 -2.0 Type III secretion bridge between inner and outermembrane lipoprotein (YscJ,HrcJ,EscJ, PscJ) compare
Pf6N2E2_4095 -1.1 -4.2 Carbonic anhydrase (EC 4.2.1.1) compare
Pf6N2E2_971 -1.1 -1.0 hypothetical protein compare
Pf6N2E2_1817 -1.1 -3.5 hypothetical protein compare
Pf6N2E2_5991 -1.1 -3.2 proteinase inhibitor compare
Pf6N2E2_3521 -1.0 -4.5 Sensor histidine kinase/response regulator compare
Pf6N2E2_5340 -1.0 -2.0 Stringent starvation protein A compare
Pf6N2E2_122 -1.0 -1.7 Tyrosine-protein kinase Wzc (EC 2.7.10.2) compare
Pf6N2E2_2176 -1.0 -0.8 Amidases related to nicotinamidase compare
Pf6N2E2_672 -1.0 -1.3 ABC-type polar amino acid transport system, ATPase component compare
Pf6N2E2_828 -1.0 -2.9 Transcriptional regulator, TetR family compare
Pf6N2E2_149 -1.0 -4.6 Inner membrane component of tripartite multidrug resistance system compare
Pf6N2E2_504 -1.0 -1.7 DNA-binding response regulator compare
Pf6N2E2_3782 -1.0 -1.1 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_3156 -1.0 -3.0 POSSIBLE MEMBRANE PROTEIN compare
Pf6N2E2_687 -1.0 -1.6 4-oxalocrotonate tautomerase (EC 5.3.2.-) compare
Pf6N2E2_4943 -1.0 -2.0 PspA/IM30 family protein compare
Pf6N2E2_349 -1.0 -2.2 hypothetical protein compare
Pf6N2E2_4061 -1.0 -2.2 Rubredoxin compare
Pf6N2E2_2072 -1.0 -2.1 hypothetical protein compare
Pf6N2E2_3206 -1.0 -0.8 hypothetical protein compare
Pf6N2E2_2124 -1.0 -1.1 Mg(2+) transport ATPase protein C compare
Pf6N2E2_344 -1.0 -1.4 hypothetical protein compare
Pf6N2E2_4945 -1.0 -3.1 FIG00955711: hypothetical protein compare
Pf6N2E2_6063 -1.0 -4.3 2-methylcitrate dehydratase FeS dependent (EC 4.2.1.79) compare
Pf6N2E2_502 -1.0 -1.7 hypothetical protein compare
Pf6N2E2_1796 -0.9 -1.6 Glycine cleavage system transcriptional activator GcvA compare
Pf6N2E2_6034 -0.9 -2.7 FIG00965471: hypothetical protein compare
Pf6N2E2_3201 -0.9 -2.4 Transcriptional regulator, MerR family compare
Pf6N2E2_3475 -0.9 -1.1 hypothetical protein compare
Pf6N2E2_3252 -0.9 -4.3 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_5428 -0.9 -3.5 DNA recombination and repair protein RecO compare
Pf6N2E2_5133 -0.9 -1.6 FIG00953980: hypothetical protein compare
Pf6N2E2_1431 -0.9 -1.3 Branched-chain amino acid transport system permease protein LivM (TC 3.A.1.4.1) compare
Pf6N2E2_3258 -0.9 -2.4 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_339 -0.9 -2.0 Glutathione-regulated potassium-efflux system protein KefC compare
Pf6N2E2_3785 -0.9 -1.7 Twin-arginine translocation protein TatB compare
Pf6N2E2_4886 -0.9 -5.1 Catalase (EC 1.11.1.6) compare


Specific Phenotypes

For 16 genes in this experiment

For stress copper (II) chloride dihydrate in Pseudomonas fluorescens FW300-N2E2

For stress copper (II) chloride dihydrate across organisms