Experiment set3IT083 for Pseudomonas fluorescens FW300-N2E2

Compare to:

LB with copper (II) chloride dihydrate 3 mM

200 most detrimental genes:

  gene name fitness t score description  
Pf6N2E2_4365 +2.3 12.0 Ribonuclease PH (EC 2.7.7.56) compare
Pf6N2E2_5549 +2.3 10.5 Copper resistance protein D compare
Pf6N2E2_3944 +2.2 6.2 Protein of unknown function DUF81 conserved
Pf6N2E2_2869 +2.1 4.8 Peptide deformylase (EC 3.5.1.88) compare
Pf6N2E2_3663 +2.0 9.2 Glycosyl transferase compare
Pf6N2E2_5865 +1.9 13.9 Chaperone protein HtpG compare
Pf6N2E2_5156 +1.9 6.1 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_5153 +1.8 8.4 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
Pf6N2E2_2277 +1.8 4.3 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_4987 +1.8 3.6 MaoC-like domain protein compare
Pf6N2E2_2447 +1.8 7.2 Probable protease htpX homolog (EC 3.4.24.-) compare
Pf6N2E2_5550 +1.7 4.8 Copper resistance protein C precursor compare
Pf6N2E2_4498 +1.7 14.1 Outer membrane porin, OprD family conserved
Pf6N2E2_4454 +1.7 9.3 Exopolyphosphatase (EC 3.6.1.11) compare
Pf6N2E2_2219 +1.6 3.6 Cell division trigger factor (EC 5.2.1.8) compare
Pf6N2E2_5406 +1.6 3.3 FIG00958224: hypothetical protein compare
Pf6N2E2_4305 +1.6 1.9 FIG00959590: hypothetical protein compare
Pf6N2E2_5703 +1.5 5.6 outer membrane protein H1 compare
Pf6N2E2_3873 +1.5 11.7 Outer membrane porin, OprD family compare
Pf6N2E2_3899 +1.5 8.2 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
Pf6N2E2_5825 +1.4 4.1 FIG00958237: hypothetical protein compare
Pf6N2E2_3656 +1.4 8.2 Probable transcription regulator Mig-14 compare
Pf6N2E2_525 +1.4 8.4 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_4638 +1.4 4.0 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_5425 +1.4 1.9 hypothetical protein compare
Pf6N2E2_6057 +1.4 3.1 FIG002781: Alpha-L-glutamate ligase family protein compare
Pf6N2E2_5331 +1.4 6.7 ATPase, AFG1 family compare
Pf6N2E2_1288 +1.3 3.1 Protein containing transglutaminase-like domain, putative cysteine protease compare
Pf6N2E2_813 +1.3 6.1 Response regulator compare
Pf6N2E2_4152 +1.3 6.9 alginate biosynthesis transcriptional regulatory protein AlgB compare
Pf6N2E2_3655 +1.3 9.0 Hypothetical protein FIG015671 in large core OS assembly cluster compare
Pf6N2E2_1674 +1.3 5.6 Hydroxymethylglutaryl-CoA synthase (EC 2.3.3.10) compare
Pf6N2E2_3664 +1.3 6.4 Carbamoyltransferase in large core OS assembly cluster compare
Pf6N2E2_4635 +1.3 6.8 ATP-dependent RNA helicase RhlE compare
Pf6N2E2_2973 +1.3 4.8 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_6058 +1.2 4.6 FIG139976: hypothetical protein compare
Pf6N2E2_3659 +1.2 4.2 Protein fixF compare
Pf6N2E2_5553 +1.2 4.6 Quinolinate synthetase (EC 2.5.1.72) compare
Pf6N2E2_2323 +1.2 4.4 Fumarate and nitrate reduction regulatory protein compare
Pf6N2E2_4614 +1.2 5.3 twitching motility protein PilH compare
Pf6N2E2_2428 +1.2 3.5 Thiol-disulfide isomerase and thioredoxins compare
Pf6N2E2_2472 +1.2 4.7 hypothetical protein compare
Pf6N2E2_2727 +1.2 6.1 Ribonuclease D (EC 3.1.26.3) compare
Pf6N2E2_3122 +1.2 2.1 Chemotaxis signal transduction protein compare
Pf6N2E2_2068 +1.2 7.0 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) compare
Pf6N2E2_5371 +1.1 7.8 Outer membrane component of tripartite multidrug resistance system compare
Pf6N2E2_4537 +1.1 2.5 Type III secretion inner membrane protein (YscS,homologous to flagellar export components) compare
Pf6N2E2_6085 +1.1 1.2 Aha1 domain superfamily compare
Pf6N2E2_5647 +1.1 4.4 Transcriptional regulator, TetR family compare
Pf6N2E2_342 +1.1 1.7 DNA-binding response regulator compare
Pf6N2E2_5243 +1.1 2.6 hypothetical protein compare
Pf6N2E2_2693 +1.1 1.9 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
Pf6N2E2_4743 +1.1 1.3 hypothetical protein compare
Pf6N2E2_1281 +1.1 2.2 ATPase involved in DNA repair compare
Pf6N2E2_3534 +1.1 1.9 Cobalamin biosynthesis protein CobG compare
Pf6N2E2_5339 +1.1 4.9 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf6N2E2_1675 +1.0 5.9 Lipid carrier protein or keto acyl-CoA thiolase Ltp3 (EC 2.3.1.16) compare
Pf6N2E2_4821 +1.0 4.4 Phosphoglycolate phosphatase (EC 3.1.3.18) compare
Pf6N2E2_3480 +1.0 2.2 Transcriptional regulator, ArsR family compare
Pf6N2E2_3569 +1.0 1.5 hypothetical protein compare
Pf6N2E2_2578 +1.0 3.7 Flagellar biosynthesis protein FliR compare
Pf6N2E2_1677 +1.0 5.2 Chalcone synthase (EC 2.3.1.74) compare
Pf6N2E2_4146 +1.0 1.2 Membrane lipoprotein lipid attachment site containing protein USSDB6D compare
Pf6N2E2_2518 +1.0 1.7 Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) / 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) compare
Pf6N2E2_2984 +1.0 2.1 LysR family transcriptional regulator PA3398 compare
Pf6N2E2_5219 +1.0 5.2 FIG140336: TPR domain protein compare
Pf6N2E2_1169 +1.0 2.1 TnpR protein compare
Pf6N2E2_3095 +1.0 1.5 hypothetical protein compare
Pf6N2E2_2285 +1.0 1.6 FIG00954079: hypothetical protein compare
Pf6N2E2_1676 +1.0 2.2 conserved protein associated with acetyl-CoA C-acyltransferase compare
Pf6N2E2_229 +1.0 2.2 Putative fumarylacetoacetate (FAA) hydrolase compare
Pf6N2E2_4570 +0.9 2.5 Cation/multidrug efflux pump compare
Pf6N2E2_146 +0.9 2.4 Transcriptional regulator, MarR family compare
Pf6N2E2_5372 +0.9 4.5 Inner membrane component of tripartite multidrug resistance system compare
Pf6N2E2_4150 +0.9 3.7 probable exported protein YPO0432 compare
Pf6N2E2_2682 +0.9 2.9 Transcriptional regulator, LysR family compare
Pf6N2E2_2795 +0.9 3.3 putative exported protein compare
Pf6N2E2_2394 +0.9 2.8 FIG006220: Hypothetical MbtH-like protein compare
Pf6N2E2_434 +0.9 1.9 hypothetical protein compare
Pf6N2E2_3096 +0.9 1.4 Periplasmic protein TonB, links inner and outer membranes compare
Pf6N2E2_241 +0.9 1.6 hypothetical protein compare
Pf6N2E2_5013 +0.9 2.7 Putative membrane protein compare
Pf6N2E2_5640 +0.9 1.0 FIG00955597: hypothetical protein compare
Pf6N2E2_1678 +0.9 5.7 Major facilitator family transporter compare
Pf6N2E2_1294 +0.9 2.1 Carbon starvation protein A compare
Pf6N2E2_3283 +0.9 4.5 Cytoplasmic axial filament protein CafA and Ribonuclease G (EC 3.1.4.-) compare
Pf6N2E2_2088 +0.9 0.9 SOS-response repressor and protease LexA (EC 3.4.21.88) compare
Pf6N2E2_2967 +0.9 2.2 Cold shock protein CspA compare
Pf6N2E2_2476 +0.9 2.5 Arylesterase precursor (EC 3.1.1.2) compare
Pf6N2E2_3109 +0.9 6.2 Outer membrane lipoprotein omp16 precursor compare
Pf6N2E2_2479 +0.9 2.5 Transcription elongation factor GreB compare
Pf6N2E2_5158 +0.9 2.1 FIG00954153: hypothetical protein compare
Pf6N2E2_1935 +0.9 2.1 Enoyl-CoA hydratase (EC 4.2.1.17) compare
Pf6N2E2_2605 +0.9 4.3 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
Pf6N2E2_4618 +0.9 2.4 Chemotaxis signal transduction protein compare
Pf6N2E2_4024 +0.9 5.5 L-Proline/Glycine betaine transporter ProP compare
Pf6N2E2_2526 +0.9 2.8 Similar to phosphoglycolate phosphatase, clustered with ubiquinone biosynthesis SAM-dependent O-methyltransferase compare
Pf6N2E2_5374 +0.8 3.5 Membrane fusion component of tripartite multidrug resistance system compare
Pf6N2E2_2315 +0.8 2.0 VapC toxin protein compare
Pf6N2E2_5768 +0.8 3.1 DNA recombination-dependent growth factor C compare
Pf6N2E2_5986 +0.8 2.2 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_4083 +0.8 2.1 hypothetical protein compare
Pf6N2E2_288 +0.8 1.4 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42); Monomeric isocitrate dehydrogenase [NADP] (EC 1.1.1.42) compare
Pf6N2E2_6164 +0.8 1.1 tRNA-Val-TAC compare
Pf6N2E2_3325 +0.8 2.0 ABC transporter, ATP-binding protein compare
Pf6N2E2_4057 +0.8 0.8 lipoprotein, putative compare
Pf6N2E2_5987 +0.8 3.7 OmpA family protein compare
Pf6N2E2_5666 +0.8 4.0 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_3326 +0.8 1.6 hypothetical protein compare
Pf6N2E2_2045 +0.8 2.9 Peptidyl-prolyl cis-trans isomerase PpiC (EC 5.2.1.8) compare
Pf6N2E2_5898 +0.8 1.7 Integral membrane protein compare
Pf6N2E2_2487 +0.8 1.1 FIG00956090: hypothetical protein compare
Pf6N2E2_1450 +0.8 0.9 FIG00960438: hypothetical protein compare
Pf6N2E2_204 +0.8 1.8 hypothetical protein compare
Pf6N2E2_495 +0.8 3.1 YD repeat protein compare
Pf6N2E2_5373 +0.8 3.7 required for cephalothin efflux, together with NodT, MFP and FUSC proteins (Pf6N2E2_5371, Pf6N2E2_5374, Pf6N2E2_5372) (from data) compare
Pf6N2E2_2473 +0.8 1.1 Major outer membrane lipoprotein I compare
Pf6N2E2_2471 +0.8 4.7 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_2375 +0.8 2.6 Response regulator NasT compare
Pf6N2E2_2264 +0.7 1.8 NADPH dependent preQ0 reductase (EC 1.7.1.13) compare
Pf6N2E2_3180 +0.7 2.7 Type IV pilus biogenesis protein PilF compare
Pf6N2E2_4499 +0.7 1.1 protein of unknown function DUF86 compare
Pf6N2E2_5476 +0.7 1.8 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf6N2E2_4541 +0.7 1.2 hypothetical protein compare
Pf6N2E2_1876 +0.7 1.1 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) compare
Pf6N2E2_5596 +0.7 2.9 Electron transport complex protein RnfG compare
Pf6N2E2_5667 +0.7 4.5 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_509 +0.7 3.1 Glutathione S-transferase, unnamed subgroup 2 (EC 2.5.1.18) compare
Pf6N2E2_304 +0.7 1.3 Anthranilate phosphoribosyltransferase like (EC 2.4.2.18) compare
Pf6N2E2_5626 +0.7 3.5 Hypothetical YciO protein, TsaC/YrdC paralog compare
Pf6N2E2_6065 +0.7 1.1 ABC transporter in pyoverdin gene cluster, periplasmic component compare
Pf6N2E2_1617 +0.7 1.1 COG2199: FOG: GGDEF domain compare
Pf6N2E2_4673 +0.7 1.8 ATP-dependent 23S rRNA helicase DbpA compare
Pf6N2E2_2822 +0.7 4.7 Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family compare
Pf6N2E2_746 +0.7 1.5 FIG00958097: hypothetical protein compare
Pf6N2E2_2842 +0.7 2.5 hypothetical protein compare
Pf6N2E2_2681 +0.7 3.7 3-phosphoglycerate kinase compare
Pf6N2E2_1009 +0.7 1.2 Inositol transport system permease protein compare
Pf6N2E2_1248 +0.7 1.9 MutT/nudix family protein compare
Pf6N2E2_3346 +0.7 2.5 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_1156 +0.7 2.0 hypothetical protein compare
Pf6N2E2_2593 +0.7 3.0 Flagellar M-ring protein FliF compare
Pf6N2E2_3568 +0.7 1.3 Unsaturated fatty acid biosythesis repressor FabR, TetR family compare
Pf6N2E2_3744 +0.7 1.0 General secretion pathway protein F compare
Pf6N2E2_5140 +0.7 2.0 Leader peptidase (Prepilin peptidase) (EC 3.4.23.43) / N-methyltransferase (EC 2.1.1.-) compare
Pf6N2E2_818 +0.7 2.8 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
Pf6N2E2_4059 +0.7 0.9 DNA-binding protein HU-alpha compare
Pf6N2E2_962 +0.7 1.0 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) compare
Pf6N2E2_2597 +0.7 4.6 Flagellar regulatory protein FleQ compare
Pf6N2E2_2402 +0.7 1.7 hypothetical protein compare
Pf6N2E2_178 +0.7 0.9 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_4276 +0.7 2.5 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_2106 +0.7 1.2 hypothetical protein compare
Pf6N2E2_1361 +0.7 2.2 Periplasmic protein p19 involved in high-affinity Fe2+ transport compare
Pf6N2E2_4391 +0.7 3.1 D-amino acid dehydrogenase small subunit (EC 1.4.99.1) compare
Pf6N2E2_1128 +0.7 1.1 Two-component response regulator compare
Pf6N2E2_5705 +0.7 0.9 Sensor protein PhoQ (EC 2.7.13.3) compare
Pf6N2E2_1433 +0.7 1.7 Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) compare
Pf6N2E2_1347 +0.7 1.4 Oxidoreductase, short-chain dehydrogenase/reductase family (EC 1.1.1.-) compare
Pf6N2E2_2934 +0.7 2.1 lipoprotein, putative compare
Pf6N2E2_371 +0.6 3.0 Histone acetyltransferase HPA2 and related acetyltransferases compare
Pf6N2E2_4548 +0.6 1.5 hypothetical protein compare
Pf6N2E2_1046 +0.6 2.8 Enoyl-CoA hydratase (EC 4.2.1.17) compare
Pf6N2E2_4517 +0.6 1.6 Putrescine transport system permease protein PotI (TC 3.A.1.11.2) compare
Pf6N2E2_4562 +0.6 1.6 L-cystine uptake protein TcyP compare
Pf6N2E2_4048 +0.6 3.5 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_5638 +0.6 3.4 Magnesium and cobalt transport protein CorA compare
Pf6N2E2_3344 +0.6 1.7 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) AmpD compare
Pf6N2E2_3870 +0.6 1.8 hypothetical protein compare
Pf6N2E2_3541 +0.6 2.7 Putative multicopper oxidases compare
Pf6N2E2_5157 +0.6 3.8 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf6N2E2_1180 +0.6 2.9 FOG: HEAT repeat compare
Pf6N2E2_4333 +0.6 3.1 Uncharacterized protein ImpD compare
Pf6N2E2_4616 +0.6 3.1 type IV pilus biogenesis protein PilJ compare
Pf6N2E2_1548 +0.6 2.0 Lactoylglutathione lyase compare
Pf6N2E2_5337 +0.6 2.9 Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) compare
Pf6N2E2_2845 +0.6 3.9 RNA polymerase associated protein RapA (EC 3.6.1.-) compare
Pf6N2E2_919 +0.6 1.0 FIG00954373: hypothetical protein compare
Pf6N2E2_2452 +0.6 3.5 Spermidine synthase (EC 2.5.1.16) compare
Pf6N2E2_5555 +0.6 0.5 Cold shock protein CspA compare
Pf6N2E2_3619 +0.6 3.2 NAD(P)HX epimerase / NAD(P)HX dehydratase compare
Pf6N2E2_2582 +0.6 1.3 Flagellar motor switch protein FliN compare
Pf6N2E2_5694 +0.6 3.1 Flagellar basal-body rod protein FlgB compare
Pf6N2E2_2590 +0.6 3.6 Flagellum-specific ATP synthase FliI compare
Pf6N2E2_5554 +0.6 2.2 FIG023103: Predicted transmembrane protein compare
Pf6N2E2_473 +0.6 1.8 putative cytochrome p450 oxidoreductase compare
Pf6N2E2_315 +0.6 2.2 probable transmembrane protein compare
Pf6N2E2_3454 +0.6 1.8 hypothetical protein compare
Pf6N2E2_2527 +0.6 2.4 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_3738 +0.6 1.3 General secretion pathway protein L compare
Pf6N2E2_4437 +0.6 2.3 Twin-arginine translocation protein TatB compare
Pf6N2E2_4438 +0.6 1.2 hypothetical protein compare
Pf6N2E2_5794 +0.6 0.7 Ribosomal large subunit pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_2872 +0.6 3.3 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) compare
Pf6N2E2_3237 +0.6 1.8 hypothetical protein compare
Pf6N2E2_2964 +0.6 1.4 FIG006285: ICC-like protein phosphoesterase compare
Pf6N2E2_775 +0.6 1.6 FIG00955061: hypothetical protein compare
Pf6N2E2_2524 +0.6 3.2 S-adenosylhomocysteine deaminase (EC 3.5.4.28); Methylthioadenosine deaminase compare
Pf6N2E2_1966 +0.6 1.7 SAM-dependent methyltransferases compare
Pf6N2E2_1249 +0.6 2.0 Transcriptional regulator, AraC family compare


Specific Phenotypes

For 16 genes in this experiment

For stress copper (II) chloride dihydrate in Pseudomonas fluorescens FW300-N2E2

For stress copper (II) chloride dihydrate across organisms