Experiment set3IT081 for Shewanella loihica PV-4

Compare to:

LB with Doxycycline hyclate 10 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
Shew_1602 +4.5 20.5 malonyl CoA-acyl carrier protein transacylase (RefSeq) compare
Shew_1058 +4.1 19.7 holo-acyl-carrier-protein synthase (RefSeq) compare
Shew_0296 +4.1 8.0 heat shock protein Hsp20 (RefSeq) compare
Shew_2087 +3.3 11.6 hypothetical protein (RefSeq) compare
Shew_2049 +3.3 18.3 DNA-binding transcriptional regulator HexR (RefSeq) compare
Shew_0755 +3.2 15.2 fructose-1,6-bisphosphate aldolase (RefSeq) compare
Shew_2473 +3.2 6.0 tetratricopeptide domain-containing protein (RefSeq) compare
Shew_2572 +3.1 14.7 enoyl-CoA hydratase/isomerase (RefSeq) compare
Shew_2174 +3.0 6.9 fatty acid metabolism regulator (RefSeq) compare
Shew_2476 +3.0 5.4 MotA/TolQ/ExbB proton channel (RefSeq) compare
Shew_2219 +3.0 8.0 hypothetical protein (RefSeq) compare
Shew_1601 +2.9 8.2 3-oxoacyl-(acyl carrier protein) synthase III (RefSeq) compare
Shew_2895 +2.7 14.5 2-dehydropantoate 2-reductase (RefSeq) compare
Shew_3708 +2.7 19.3 TetR family transcriptional regulator (RefSeq) compare
Shew_0728 +2.6 20.1 dihydroorotase (RefSeq) compare
Shew_2086 +2.5 2.4 hypothetical protein (RefSeq) compare
Shew_1341 +2.4 11.5 anti-sigma-28 factor, FlgM (RefSeq) compare
Shew_3225 +2.3 16.8 glutathione synthetase (RefSeq) compare
Shew_3487 pyrE +2.3 18.0 orotate phosphoribosyltransferase (RefSeq) compare
Shew_1823 +2.3 8.6 putative AcnD-accessory protein PrpF (RefSeq) compare
Shew_1563 +2.3 14.8 isocitrate dehydrogenase, NADP-dependent (RefSeq) compare
Shew_1013 +2.3 21.8 aspartate carbamoyltransferase (RefSeq) compare
Shew_0534 +2.3 11.3 major facilitator transporter (RefSeq) compare
Shew_1810 +2.2 17.4 dihydroorotate dehydrogenase 2 (RefSeq) compare
Shew_2013 +2.2 2.5 putative DNA-binding transcriptional regulator (RefSeq) compare
Shew_1819 +2.2 7.1 GntR family transcriptional regulator (RefSeq) compare
Shew_1298 guaA +2.2 12.8 bifunctional GMP synthase/glutamine amidotransferase protein (RefSeq) compare
Shew_3410 +2.1 14.6 permease (RefSeq) compare
Shew_2642 +2.1 7.3 flavodoxin (RefSeq) compare
Shew_1202 +2.1 10.3 (p)ppGpp synthetase I, SpoT/RelA (RefSeq) compare
Shew_3273 +2.1 7.6 hypothetical protein (RefSeq) compare
Shew_3499 +2.0 9.0 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) compare
Shew_2000 +2.0 5.2 glyceraldehyde-3-phosphate dehydrogenase (RefSeq) compare
Shew_2496 +2.0 5.1 phage shock protein A, PspA (RefSeq) compare
Shew_3660 +2.0 18.1 glutathione reductase (RefSeq) compare
Shew_2668 +1.9 9.6 2-nitropropane dioxygenase, NPD (RefSeq) compare
Shew_0383 +1.9 11.2 malate dehydrogenase (RefSeq) compare
Shew_1224 +1.9 14.6 sodium:dicarboxylate symporter (RefSeq) compare
Shew_1227 +1.8 4.1 glutamate--cysteine ligase (RefSeq) compare
Shew_3682 +1.8 14.8 two component, sigma54 specific, Fis family transcriptional regulator (RefSeq) compare
Shew_2839 +1.8 17.2 carbamoyl phosphate synthase small subunit (RefSeq) compare
Shew_2838 carB +1.8 14.5 carbamoyl phosphate synthase large subunit (RefSeq) compare
Shew_1713 +1.7 2.9 3-oxoacyl-(acyl carrier protein) synthase III (RefSeq) compare
Shew_3378 +1.7 3.6 Sec-independent protein translocase, TatC subunit (RefSeq) compare
Shew_3681 +1.7 13.9 integral membrane sensor signal transduction histidine kinase (RefSeq) compare
Shew_3431 aceE +1.6 13.3 pyruvate dehydrogenase subunit E1 (RefSeq) compare
Shew_2409 +1.6 5.1 short chain dehydrogenase (RefSeq) compare
Shew_3709 +1.6 11.1 2-amino-3-ketobutyrate coenzyme A ligase (RefSeq) compare
Shew_1050 +1.5 9.7 sigma E regulatory protein, MucB/RseB (RefSeq) compare
Shew_3710 tdh +1.5 12.9 L-threonine 3-dehydrogenase (RefSeq) compare
Shew_3266 dipZ +1.5 3.1 thiol:disulfide interchange protein precursor (RefSeq) compare
Shew_1688 +1.5 6.4 TonB-dependent receptor (RefSeq) compare
Shew_0421 +1.5 1.4 phage shock protein C, PspC (RefSeq) compare
Shew_3430 +1.5 4.7 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase (RefSeq) compare
Shew_2667 +1.5 10.6 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ (RefSeq) compare
Shew_3432 pdhR +1.5 5.9 transcriptional regulator PdhR (RefSeq) compare
Shew_1407 +1.4 11.1 short-chain dehydrogenase/reductase SDR (RefSeq) compare
Shew_3500 +1.4 4.4 putative endoribonuclease L-PSP (RefSeq) compare
Shew_2666 +1.4 10.4 omega-3 polyunsaturated fatty acid synthase PfaB (RefSeq) compare
Shew_1657 sucC +1.4 1.7 succinyl-CoA synthetase subunit beta (RefSeq) compare
Shew_2665 +1.4 11.4 beta-ketoacyl synthase (RefSeq) compare
Shew_2115 +1.4 5.0 lytic transglycosylase, catalytic (RefSeq) compare
Shew_1092 +1.4 7.7 amino acid carrier protein (RefSeq) compare
Shew_2664 +1.4 4.9 transcriptional regulator, putative (RefSeq) compare
Shew_3295 +1.3 6.6 AFG1 family ATPase (RefSeq) compare
Shew_3247 +1.3 1.3 hypothetical protein (RefSeq) compare
Shew_1867 +1.3 4.4 hypothetical protein (RefSeq) compare
Shew_3696 +1.2 4.5 CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase (RefSeq) compare
Shew_1437 +1.2 7.6 transcriptional regulator, TyrR (RefSeq) compare
Shew_2573 +1.2 7.5 carbamoyl-phosphate synthase L chain, ATP-binding (RefSeq) compare
Shew_3271 +1.2 7.1 galactokinase (RefSeq) compare
Shew_0799 +1.2 3.4 MarR family transcriptional regulator (RefSeq) compare
Shew_1021 +1.2 7.2 peptidase M23B (RefSeq) compare
Shew_3711 +1.2 1.2 rhodanese domain-containing protein (RefSeq) compare
Shew_2410 +1.2 1.3 beta-ketoacyl synthase (RefSeq) compare
Shew_2740 +1.1 1.1 YfaZ family protein (RefSeq) compare
Shew_1820 prpB +1.1 3.6 2-methylisocitrate lyase (RefSeq) compare
Shew_2656 +1.1 5.5 4'-phosphopantetheinyl transferase (RefSeq) compare
Shew_1411 +1.1 9.2 hexapaptide repeat-containing transferase (RefSeq) compare
Shew_2176 +1.1 1.3 disulphide bond formation protein DsbB (RefSeq) compare
Shew_1714 +1.1 1.9 alpha/beta hydrolase fold (RefSeq) compare
Shew_2558 +1.1 3.6 1,4-dihydroxy-2-naphthoate octaprenyltransferase (RefSeq) compare
Shew_1865 +1.1 4.7 phosphoenolpyruvate-protein phosphotransferase (RefSeq) compare
Shew_3702 +1.0 1.5 glycosyl transferase family protein (RefSeq) compare
Shew_2502 +1.0 3.0 ABC transporter-related protein (RefSeq) compare
Shew_0225 +1.0 0.7 phosphoheptose isomerase (RefSeq) compare
Shew_0833 +1.0 1.4 hypoxanthine-guanine phosphoribosyltransferase (RefSeq) compare
Shew_0659 +1.0 4.8 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (RefSeq) compare
Shew_0854 +1.0 4.7 hypothetical protein (RefSeq) compare
Shew_3522 +1.0 1.9 hypothetical protein (RefSeq) compare
Shew_1445 +1.0 0.9 dicarboxylate TRAP transporter (succinate, fumarate, L-malate, and alpha-ketoglutarate), small permease component (from data) compare
Shew_0127 +1.0 2.4 LexA repressor (RefSeq) compare
Shew_1883 +1.0 0.9 hypothetical protein (RefSeq) compare
Shew_3324 +1.0 2.5 hypothetical protein (RefSeq) compare
Shew_2918 +1.0 1.0 hypothetical protein (RefSeq) compare
Shew_3697 +1.0 4.6 glycosyl transferase family protein (RefSeq) compare
Shew_1397 +0.9 3.1 amino acid/peptide transporter (RefSeq) compare
Shew_0086 +0.9 7.7 electron-transferring-flavoproteindehydrogenase (RefSeq) compare
Shew_1606 +0.9 0.9 hypothetical protein (RefSeq) compare
Shew_0098 +0.9 5.4 integral membrane sensor signal transduction histidine kinase (RefSeq) compare
Shew_0193 +0.9 3.5 cytochrome c-type biogenesis protein CcmF (RefSeq) compare
Shew_2320 +0.9 5.9 RNA methyltransferase (RefSeq) compare
Shew_0966 +0.9 1.1 beta alanine--pyruvate transaminase (RefSeq) compare
Shew_1287 +0.9 3.2 hypothetical protein (RefSeq) compare
Shew_2571 +0.9 3.4 propionyl-CoA carboxylase (RefSeq) compare
Shew_2956 +0.9 1.8 ECF subfamily RNA polymerase sigma-24 factor (RefSeq) compare
Shew_2906 +0.9 1.1 hypothetical protein (RefSeq) compare
Shew_1146 +0.9 3.3 hypothetical protein (RefSeq) compare
Shew_3695 +0.9 1.3 cytidyltransferase-like protein (RefSeq) compare
Shew_1078 +0.9 6.8 peptidylprolyl isomerase, FKBP-type (RefSeq) compare
Shew_0618 +0.9 1.3 hypothetical protein (RefSeq) compare
Shew_3664 +0.9 7.0 alpha-L-glutamate ligase (RefSeq) compare
Shew_1809 +0.9 5.3 NAD-glutamate dehydrogenase (RefSeq) compare
Shew_0469 +0.9 0.7 pentapeptide repeat-containing protein (RefSeq) compare
Shew_3772 +0.9 1.3 thioesterase superfamily protein (RefSeq) compare
Shew_3581 +0.9 3.5 peptidase M16 domain-containing protein (RefSeq) compare
Shew_0327 +0.9 1.8 HupE/UreJ protein (RefSeq) compare
Shew_3716 +0.8 2.2 cytochrome c, class I (RefSeq) compare
Shew_2584 +0.8 6.0 electron transfer flavoprotein beta-subunit (RefSeq) compare
Shew_1854 +0.8 1.3 hypothetical protein (RefSeq) compare
Shew_1920 +0.8 4.0 alpha/beta hydrolase fold (RefSeq) compare
Shew_1404 +0.8 5.2 dTDP-4-dehydrorhamnose 3,5-epimerase (RefSeq) compare
Shew_3545 rbn +0.8 3.7 ribonuclease BN (RefSeq) compare
Shew_0316 +0.8 3.0 protein of unknown function DUF513, hemX (RefSeq) compare
Shew_3316 +0.8 3.8 magnesium transporter (RefSeq) compare
Shew_3434 +0.8 6.2 N-acetyl-anhydromuranmyl-L-alanine amidase (RefSeq) compare
Shew_1731 +0.8 0.9 histidine triad (HIT) protein (RefSeq) compare
Shew_1122 +0.8 3.9 hypothetical protein (RefSeq) compare
Shew_1477 +0.8 2.9 anti-ECFsigma factor, ChrR (RefSeq) compare
Shew_2437 +0.8 1.0 hypothetical protein (RefSeq) compare
Shew_2857 +0.8 1.4 LysR family transcriptional regulator (RefSeq) compare
Shew_3313 +0.8 1.5 PTS IIA-like nitrogen-regulatory protein PtsN (RefSeq) compare
Shew_1886 +0.8 2.7 alpha amylase, catalytic region (RefSeq) compare
Shew_3657 +0.8 6.3 oligopeptidase A (RefSeq) compare
Shew_1431 +0.8 1.6 hypothetical protein (RefSeq) compare
Shew_1423 +0.8 0.7 sulfate adenylyltransferase, large subunit (RefSeq) compare
Shew_3122 +0.8 0.8 PepSY-associated TM helix domain-containing protein (RefSeq) compare
Shew_2570 +0.8 6.5 acyl-CoA dehydrogenase domain-containing protein (RefSeq) compare
Shew_1906 +0.8 1.7 GCN5-related N-acetyltransferase (RefSeq) compare
Shew_2416 +0.7 1.0 chorismate synthase (RefSeq) compare
Shew_3341 +0.7 1.3 diguanylate cyclase with GAF sensor (RefSeq) compare
Shew_3064 gcvT +0.7 5.4 glycine cleavage system aminomethyltransferase T (RefSeq) compare
Shew_2236 +0.7 2.3 adenine phosphoribosyltransferase (RefSeq) compare
Shew_0468 +0.7 2.9 LysR family transcriptional regulator (RefSeq) compare
Shew_0024 +0.7 0.7 ArsR family transcriptional regulator (RefSeq) compare
Shew_0698 +0.7 3.0 Na+/H+ antiporter NhaC (RefSeq) compare
Shew_3267 +0.7 3.3 sodium/hydrogen exchanger (RefSeq) compare
Shew_0495 +0.7 0.8 hypothetical protein (RefSeq) compare
Shew_1264 +0.7 1.1 UvrD/REP helicase (RefSeq) compare
Shew_3336 +0.7 0.9 MarR family transcriptional regulator (RefSeq) compare
Shew_1590 +0.7 0.6 2OG-Fe(II) oxygenase (RefSeq) compare
Shew_0224 +0.7 1.8 transport-associated (RefSeq) compare
Shew_3814 +0.7 5.0 naphthoate synthase (RefSeq) compare
Shew_2033 +0.7 1.3 hypothetical protein (RefSeq) compare
Shew_3622 hslO +0.7 2.8 Hsp33-like chaperonin (RefSeq) compare
Shew_1577 +0.7 0.7 aminotransferase, class IV (RefSeq) compare
Shew_3131 +0.7 4.0 poly(A) polymerase (RefSeq) compare
Shew_1125 +0.7 1.5 hypothetical protein (RefSeq) compare
Shew_R0049 +0.7 3.2 tRNA-Pro (RefSeq) compare
Shew_0521 metL +0.7 3.8 bifunctional aspartate kinase II/homoserine dehydrogenase II (RefSeq) compare
Shew_2646 +0.7 0.7 hypothetical protein (RefSeq) compare
Shew_3363 +0.7 1.5 3-dehydroquinate dehydratase, type II (RefSeq) compare
Shew_3799 +0.7 1.3 hypothetical protein (RefSeq) compare
Shew_1741 +0.7 2.0 beta-lactamase domain-containing protein (RefSeq) compare
Shew_0615 +0.7 3.1 bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase (RefSeq) compare
Shew_0584 +0.7 0.9 hypothetical protein (RefSeq) compare
Shew_1123 +0.7 3.5 A/G-specific adenine glycosylase (RefSeq) compare
Shew_1681 +0.7 2.0 diguanylate cyclase with PAS/PAC sensor (RefSeq) compare
Shew_1717 +0.7 1.0 globin (RefSeq) compare
Shew_1822 +0.7 5.1 aconitate hydratase (RefSeq) compare
Shew_1667 +0.7 2.0 acetyl-CoA acetyltransferase (RefSeq) compare
Shew_1076 +0.7 1.6 Trp operon repressor (RefSeq) compare
Shew_3540 +0.7 3.5 NapC/NirT cytochrome c domain-containing protein (RefSeq) compare
Shew_2165 +0.7 2.2 aldose 1-epimerase (RefSeq) compare
Shew_2730 +0.7 1.1 glutathione S-transferase domain-containing protein (RefSeq) compare
Shew_0585 +0.7 1.8 cAMP-regulatory protein (RefSeq) compare
Shew_0099 +0.6 3.6 pseudouridine synthase Rlu family protein (RefSeq) compare
Shew_2907 +0.6 1.6 invasion gene expression up-regulator, SirB (RefSeq) compare
Shew_3495 +0.6 1.3 hypothetical protein (RefSeq) compare
Shew_2962 +0.6 3.4 malate dehydrogenase (RefSeq) compare
Shew_2795 +0.6 3.1 xanthine/uracil/vitamin C permease (RefSeq) compare
Shew_3602 +0.6 4.8 O-succinylbenzoate-CoA ligase (RefSeq) compare
Shew_0883 +0.6 2.7 aminoglycoside phosphotransferase (RefSeq) compare
Shew_0594 +0.6 1.3 hypothetical protein (RefSeq) compare
Shew_0640 +0.6 1.0 TPR repeat-containing protein (RefSeq) compare
Shew_3631 +0.6 1.4 hypothetical protein (RefSeq) compare
Shew_2644 +0.6 1.7 hypothetical protein (RefSeq) compare
Shew_0889 +0.6 1.1 hypothetical protein (RefSeq) compare
Shew_2789 +0.6 1.4 hypothetical protein (RefSeq) compare
Shew_1969 +0.6 1.6 two component LuxR family transcriptional regulator (RefSeq) compare
Shew_0614 +0.6 2.2 cysteine/glutathione ABC transporter membrane/ATP-binding component (RefSeq) compare
Shew_2120 +0.6 1.6 hypothetical protein (RefSeq) compare
Shew_0570 +0.6 1.0 ubiquinol-cytochrome c reductase, iron-sulfur subunit (RefSeq) compare
Shew_1156 +0.6 1.2 hypothetical protein (RefSeq) compare
Shew_1365 +0.6 0.5 flagellar hook-basal body complex subunit FliE (RefSeq) compare
Shew_2425 fadJ +0.6 2.3 multifunctional fatty acid oxidation complex subunit alpha (RefSeq) compare
Shew_2978 +0.6 1.5 extracellular solute-binding protein (RefSeq) compare
Shew_3473 +0.6 4.3 response regulator receiver protein (RefSeq) compare
Shew_1020 anmK +0.6 2.0 anhydro-N-acetylmuramic acid kinase (RefSeq) compare
Shew_0438 +0.6 0.6 GumN family protein (RefSeq) compare


Specific Phenotypes

None in this experiment

For Shewanella loihica PV-4 in stress experiments

For stress Doxycycline hyclate across organisms