Experiment set3IT079 for Sphingomonas koreensis DSMZ 15582

Compare to:

a-Cyclodextrin carbon source

200 most detrimental genes:

  gene name fitness t score description  
Ga0059261_0131 +4.4 24.7 hypothetical protein compare
Ga0059261_1287 +3.4 29.2 poly(R)-hydroxyalkanoic acid synthase, class I compare
Ga0059261_1846 +3.4 25.8 Xaa-Pro aminopeptidase compare
Ga0059261_1312 +3.1 16.7 amino acid/peptide transporter (Peptide:H+ symporter), bacterial compare
Ga0059261_1451 +2.9 17.9 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) compare
Ga0059261_0038 +2.5 15.5 Transcriptional regulators compare
Ga0059261_1601 +2.0 8.7 protein-(glutamine-N5) methyltransferase, release factor-specific compare
Ga0059261_2189 +1.9 13.8 uncharacterized domain 1 compare
Ga0059261_4186 +1.7 4.8 Phosphopantetheine attachment site compare
Ga0059261_3671 +1.6 4.2 Citrate lyase beta subunit compare
Ga0059261_3926 +1.6 14.4 L-proline dehydrogenase (EC 1.5.99.8)/delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) compare
Ga0059261_3490 +1.5 11.4 Response regulator receiver domain/Sigma-70, region 4 compare
Ga0059261_4055 +1.5 11.7 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) compare
Ga0059261_4056 +1.5 12.1 Acetyl/propionyl-CoA carboxylase, alpha subunit compare
Ga0059261_4187 +1.5 11.9 acyl-CoA ligase (AMP-forming), exosortase A-associated compare
Ga0059261_0657 +1.4 3.5 Uncharacterized protein conserved in bacteria compare
Ga0059261_4188 +1.4 9.5 pyridoxal-dependent decarboxylase, exosortase A system-associated compare
Ga0059261_3657 +1.3 9.5 His Kinase A (phospho-acceptor) domain/Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase compare
Ga0059261_0879 +1.3 11.1 ribosomal RNA small subunit methyltransferase A compare
Ga0059261_0875 +1.3 4.0 Leucyl aminopeptidase compare
Ga0059261_2978 +1.3 5.8 Transcriptional regulators compare
Ga0059261_1303 +1.2 5.5 hypothetical protein compare
Ga0059261_3925 +1.2 7.2 Transcriptional regulators compare
Ga0059261_1472 +1.2 1.7 hypothetical protein compare
Ga0059261_3810 +1.1 6.2 Transcriptional regulators compare
Ga0059261_3783 +1.1 6.6 hypothetical protein compare
Ga0059261_3121 +1.1 7.7 asparagine synthase (glutamine-hydrolyzing) compare
Ga0059261_1368 +1.1 2.9 hypothetical protein compare
Ga0059261_3100 +1.1 9.1 Sugar transferases involved in lipopolysaccharide synthesis compare
Ga0059261_2746 +1.1 5.3 Predicted sugar nucleotidyltransferases compare
Ga0059261_0555 +1.0 9.0 transcriptional regulator, LacI family compare
Ga0059261_3579 +1.0 5.8 hypothetical protein compare
Ga0059261_3114 +1.0 7.9 hypothetical protein compare
Ga0059261_2187 +1.0 8.2 Cell Wall Hydrolase compare
Ga0059261_0201 +1.0 8.3 Na+/H+-dicarboxylate symporters compare
Ga0059261_1608 +1.0 7.4 Phosphate starvation-inducible protein PhoH, predicted ATPase compare
Ga0059261_3127 +1.0 6.4 hypothetical protein compare
Ga0059261_3097 +1.0 6.6 Calcineurin-like phosphoesterase compare
Ga0059261_1419 +1.0 5.6 fructose-6-phosphate aldolase, TalC/MipB family compare
Ga0059261_3581 +0.9 4.3 Alpha/beta hydrolase family compare
Ga0059261_3130 +0.9 6.7 Lipid A core - O-antigen ligase and related enzymes compare
Ga0059261_3492 +0.9 5.9 RNA polymerase sigma factor, sigma-70 family compare
Ga0059261_4022 +0.9 6.3 Signal transduction histidine kinase compare
Ga0059261_2020 +0.9 7.0 Glycosyltransferase compare
Ga0059261_0790 +0.8 2.3 putative membrane protein insertion efficiency factor compare
Ga0059261_2019 +0.8 2.7 Uncharacterized protein conserved in bacteria compare
Ga0059261_3119 +0.8 3.6 asparagine synthase (glutamine-hydrolyzing) compare
Ga0059261_0493 +0.8 2.0 hypothetical protein compare
Ga0059261_1924 +0.8 7.2 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes compare
Ga0059261_1911 +0.8 1.9 Thioredoxin-like proteins and domains compare
Ga0059261_0266 +0.8 1.6 hypothetical protein compare
Ga0059261_2215 +0.8 1.7 Thiamine monophosphate synthase compare
Ga0059261_1985 +0.8 2.3 transcriptional regulator NrdR compare
Ga0059261_3784 +0.7 6.3 DNA mismatch repair protein MutS compare
Ga0059261_2504 +0.7 5.7 ribosome silencing factor RsfS/YbeB/iojap compare
Ga0059261_3129 +0.7 5.4 SLBB domain/Polysaccharide biosynthesis/export protein compare
Ga0059261_0848 +0.7 5.5 transcriptional regulator, TetR family compare
Ga0059261_3698 +0.7 5.9 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Ga0059261_1381 +0.7 3.9 Membrane protease subunits, stomatin/prohibitin homologs compare
Ga0059261_1912 +0.7 2.8 Nitroreductase compare
Ga0059261_1380 +0.7 5.4 Membrane protease subunits, stomatin/prohibitin homologs compare
Ga0059261_1339 +0.6 1.3 hypothetical protein compare
Ga0059261_2271 +0.6 4.6 branched-chain alpha-keto acid dehydrogenase E2 component (EC 2.3.1.168) compare
Ga0059261_3128 +0.6 5.4 capsular exopolysaccharide family compare
Ga0059261_1560 +0.6 2.1 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain compare
Ga0059261_1837 +0.6 2.0 Staphylococcal nuclease homologue compare
Ga0059261_3962 +0.6 5.0 N-formylglutamate deformylase (EC 3.5.1.68) (from data) compare
Ga0059261_2188 +0.6 1.6 Uncharacterized conserved protein compare
Ga0059261_0920 +0.6 2.9 rRNA methylases compare
Ga0059261_0209 +0.6 5.2 His Kinase A (phospho-acceptor) domain/Response regulator receiver domain/Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase compare
Ga0059261_3652 +0.6 4.2 phosphate transport system regulatory protein PhoU compare
Ga0059261_3842 +0.6 5.4 PAS domain S-box compare
Ga0059261_0057 +0.6 5.3 Glycosyltransferase compare
Ga0059261_2471 +0.6 0.8 hypothetical protein compare
Ga0059261_0059 +0.6 1.7 Stress-induced morphogen (activity unknown) compare
Ga0059261_3638 +0.6 1.7 Predicted integral membrane protein (DUF2282) compare
Ga0059261_1462 +0.5 4.9 Transcriptional regulators compare
Ga0059261_2368 +0.5 1.6 Phage baseplate assembly protein W compare
Ga0059261_2754 +0.5 5.1 ABC-type branched-chain amino acid transport systems, periplasmic component compare
Ga0059261_1414 +0.5 3.2 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF compare
Ga0059261_0208 +0.5 2.6 Response regulator receiver domain compare
Ga0059261_3287 +0.5 4.1 Topoisomerase IB compare
Ga0059261_0951 +0.5 3.7 hypothetical protein compare
Ga0059261_0305 +0.5 3.1 bacterioferritin compare
Ga0059261_1763 +0.5 2.2 hypothetical protein compare
Ga0059261_3491 +0.5 3.6 hypothetical protein compare
Ga0059261_0390 +0.5 1.6 Ribbon-helix-helix protein, copG family compare
Ga0059261_4139 +0.5 2.0 hypothetical protein compare
Ga0059261_0227 +0.5 1.3 hypothetical protein compare
Ga0059261_1561 +0.5 2.3 Signal transduction histidine kinase compare
Ga0059261_2913 +0.5 2.1 Type IV secretory pathway, VirB2 components (pilins) compare
Ga0059261_3431 +0.5 3.0 Uncharacterized protein conserved in bacteria compare
Ga0059261_2581 +0.5 2.5 Uncharacterized conserved protein (DUF2285) compare
Ga0059261_4185 +0.5 1.3 hypothetical protein compare
Ga0059261_0045 +0.5 1.5 hypothetical protein compare
Ga0059261_4054 +0.5 1.1 Uncharacterized protein conserved in bacteria compare
Ga0059261_3309 +0.5 3.7 formate-dependent phosphoribosylglycinamide formyltransferase (EC 6.3.4.-) compare
Ga0059261_0155 +0.5 3.5 peroxiredoxin compare
Ga0059261_0578 +0.5 3.7 Major Facilitator Superfamily compare
Ga0059261_2528 +0.4 1.8 Uncharacterized conserved protein compare
Ga0059261_3094 +0.4 3.0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase/FKBP-type peptidyl-prolyl cis-trans isomerase compare
Ga0059261_3236 +0.4 3.9 pyruvate phosphate dikinase (EC 2.7.9.1) compare
Ga0059261_2076 +0.4 1.2 hypothetical protein compare
Ga0059261_0656 +0.4 1.6 Predicted dehydrogenases and related proteins compare
Ga0059261_0023 +0.4 3.3 tRNA:m(5)U-54 methyltransferase compare
Ga0059261_3979 +0.4 1.8 elongation factor 4 compare
Ga0059261_3265 +0.4 3.5 Glycerol-3-phosphate dehydrogenase compare
Ga0059261_4025 +0.4 1.5 Nucleotidyl transferase compare
Ga0059261_1119 +0.4 1.4 Chemotaxis signal transduction protein compare
Ga0059261_3833 +0.4 1.8 hypothetical protein compare
Ga0059261_3693 +0.4 3.2 Putative arginyl-tRNA:protein arginylyltransferase compare
Ga0059261_1423 +0.4 3.1 Trypsin-like peptidase domain compare
Ga0059261_0982 +0.4 3.0 acetyl-CoA acetyltransferases compare
Ga0059261_4008 +0.4 3.1 Alpha/beta hydrolase family compare
Ga0059261_1756 +0.4 1.7 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes compare
Ga0059261_0993 +0.4 1.0 Methylase involved in ubiquinone/menaquinone biosynthesis compare
Ga0059261_3266 +0.4 3.7 ribonuclease R compare
Ga0059261_3613 +0.4 2.3 Dihydroneopterin aldolase compare
Ga0059261_2062 +0.4 2.3 flagellar biosynthetic protein FliP compare
Ga0059261_0083 +0.4 0.7 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B (EC 6.3.5.-) compare
Ga0059261_3440 +0.4 0.9 hypothetical protein compare
Ga0059261_0039 +0.4 2.4 His Kinase A (phospho-acceptor) domain compare
Ga0059261_4120 +0.4 0.7 Stress responsive A/B Barrel Domain compare
Ga0059261_3403 +0.4 2.9 Uncharacterized protein conserved in bacteria compare
Ga0059261_1707 +0.4 1.8 hypothetical protein compare
Ga0059261_1565 +0.4 3.2 cytochrome bo3 quinol oxidase subunit 1 apoprotein (EC 1.10.3.-) compare
Ga0059261_1566 +0.4 2.6 cytochrome o ubiquinol oxidase subunit II compare
Ga0059261_3251 +0.4 1.7 Transcriptional regulator compare
Ga0059261_1758 +0.4 2.6 hypothetical protein compare
Ga0059261_1564 +0.4 2.0 cytochrome bo3 quinol oxidase subunit 3 (EC 1.10.3.-) compare
Ga0059261_2768 +0.4 1.1 hypothetical protein compare
Ga0059261_4149 +0.3 2.1 psp operon transcriptional activator PspF compare
Ga0059261_3368 +0.3 1.7 Predicted transcriptional regulator compare
Ga0059261_2089 +0.3 1.8 flagellar basal-body rod protein FlgB compare
Ga0059261_3026 +0.3 1.3 Cation efflux family compare
Ga0059261_2018 +0.3 2.7 hypothetical protein compare
Ga0059261_1109 +0.3 1.6 Flagellar biosynthesis protein, FliO compare
Ga0059261_2951 +0.3 1.2 Heavy-metal resistance compare
Ga0059261_2074 +0.3 2.5 Sigma-54 interaction domain/Bacterial regulatory protein, Fis family compare
Ga0059261_3208 +0.3 0.9 hypothetical protein compare
Ga0059261_0686 +0.3 2.6 haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED/haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E compare
Ga0059261_0302 +0.3 2.1 hypothetical protein compare
Ga0059261_1578 +0.3 2.5 Rhodanese-like domain compare
Ga0059261_0750 +0.3 1.6 NADH:ubiquinone oxidoreductase subunit 3 (chain A) compare
Ga0059261_1991 +0.3 1.9 hypothetical protein compare
Ga0059261_1562 +0.3 2.2 Uncharacterized conserved protein compare
Ga0059261_2745 +0.3 2.6 Myo-inositol-1-phosphate synthase compare
Ga0059261_2743 +0.3 1.8 hypothetical protein compare
Ga0059261_4145 +0.3 2.1 phage shock protein C (PspC) family protein compare
Ga0059261_0130 +0.3 2.2 Predicted lactoylglutathione lyase compare
Ga0059261_3899 +0.3 2.5 Alanine dehydrogenase (EC 1.4.1.1) (from data) compare
Ga0059261_1905 +0.3 2.6 Serine acetyltransferase compare
Ga0059261_1384 +0.3 3.0 Domain of unknown function (DUF377) compare
Ga0059261_1759 +0.3 1.5 Phosphoadenosine phosphosulfate reductase family compare
Ga0059261_2907 +0.3 1.8 Acyl-CoA dehydrogenases compare
Ga0059261_3799 +0.3 1.1 hypothetical protein compare
Ga0059261_2708 +0.3 1.7 hypothetical protein compare
Ga0059261_2548 +0.3 1.1 tRNA compare
Ga0059261_3477 +0.3 2.7 Uncharacterized membrane-associated protein compare
Ga0059261_0132 +0.3 1.9 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family compare
Ga0059261_3227 +0.3 1.0 GTP-binding protein YchF compare
Ga0059261_2744 +0.3 2.5 CDP-alcohol phosphatidyltransferase compare
Ga0059261_3604 +0.3 1.3 Uncharacterized protein conserved in bacteria compare
Ga0059261_3862 +0.3 1.2 Multidrug resistance efflux pump compare
Ga0059261_1301 +0.3 1.4 Methyltransferase domain compare
Ga0059261_0284 +0.3 2.0 Leucyl aminopeptidase compare
Ga0059261_0340 +0.3 0.9 Bacterial protein of unknown function (DUF937) compare
Ga0059261_0887 +0.3 1.3 Predicted transcriptional regulators compare
Ga0059261_1292 +0.3 1.2 hypothetical protein compare
Ga0059261_0494 +0.3 1.1 ABC-type antimicrobial peptide transport system, ATPase component compare
Ga0059261_2697 +0.3 2.8 Membrane carboxypeptidase/penicillin-binding protein compare
Ga0059261_2065 +0.3 1.7 Flagellar motor switch protein compare
Ga0059261_0723 +0.3 1.2 hypothetical protein compare
Ga0059261_2593 +0.3 1.0 hypothetical protein compare
Ga0059261_3085 +0.3 1.1 Predicted transcriptional regulators compare
Ga0059261_2227 +0.3 2.6 aminodeoxychorismate synthase, component I, bacterial clade compare
Ga0059261_3052 +0.3 1.8 Uncharacterized conserved protein (DUF2285) compare
Ga0059261_4184 +0.3 1.2 exosortase A system-associated hydrolase 1 compare
Ga0059261_1563 +0.3 0.9 cytochrome bo3 quinol oxidase subunit 4 (EC 1.10.3.-) compare
Ga0059261_0035 +0.3 0.9 Uncharacterized protein conserved in bacteria compare
Ga0059261_3518 +0.3 2.4 RND family efflux transporter, MFP subunit compare
Ga0059261_2398 +0.3 1.7 hypothetical protein compare
Ga0059261_4214 +0.3 1.5 Enoyl-CoA hydratase/carnithine racemase compare
Ga0059261_2071 +0.3 1.2 flagellar motor switch protein FliG compare
Ga0059261_2094 +0.3 2.0 flagellar basal-body rod protein FlgG, Gram-negative bacteria compare
Ga0059261_1757 +0.3 1.5 Protein of unknown function (DUF4007) compare
Ga0059261_1505 +0.3 1.7 Lyzozyme M1 (1,4-beta-N-acetylmuramidase) compare
Ga0059261_2017 +0.3 2.2 Glycosyltransferase compare
Ga0059261_3594 +0.3 2.0 hypothetical protein compare
Ga0059261_3356 +0.3 0.6 hypothetical protein compare
Ga0059261_1039 +0.3 1.9 hypothetical protein compare
Ga0059261_3834 +0.3 1.8 Molecular chaperone (small heat shock protein) compare
Ga0059261_0601 +0.3 2.1 Methyltransferase domain compare
Ga0059261_0921 +0.3 0.7 hypothetical protein compare
Ga0059261_4199 +0.3 2.3 asparagine synthase (glutamine-hydrolyzing) compare
Ga0059261_1265 +0.3 1.1 hypothetical protein compare
Ga0059261_1415 +0.3 1.6 UDP-N-acetylmuramate-alanine ligase compare
Ga0059261_2725 +0.3 1.3 hypothetical protein compare
Ga0059261_1259 +0.3 1.5 Ribbon-helix-helix domain compare
Ga0059261_2082 +0.3 2.2 flagellar biosynthesis protein FlhA compare


Specific Phenotypes

For 16 genes in this experiment

For carbon source a-Cyclodextrin in Sphingomonas koreensis DSMZ 15582

For carbon source a-Cyclodextrin across organisms