Experiment set3IT077 for Sphingomonas koreensis DSMZ 15582

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D-Xylose carbon source

200 most important genes:

  gene name fitness t score description  
Ga0059261_1894 -5.4 -7.4 D-xylose 1-dehydrogenase (EC 1.1.1.175) (from data) conserved
Ga0059261_0014 -5.4 -7.4 phosphopyruvate hydratase compare
Ga0059261_2530 -5.1 -13.1 N-acetylglutamate kinase (EC 2.7.2.8) compare
Ga0059261_1281 -5.0 -11.2 histidinol dehydrogenase compare
Ga0059261_0070 -4.8 -10.2 phosphoserine phosphatase SerB compare
Ga0059261_4225 -4.8 -7.2 3-isopropylmalate dehydratase, small subunit compare
Ga0059261_0290 -4.8 -4.6 3-dehydroquinate dehydratase (EC 4.2.1.10) compare
Ga0059261_3637 -4.7 -3.3 Uncharacterized protein conserved in bacteria compare
Ga0059261_1393 -4.7 -20.1 argininosuccinate synthase (EC 6.3.4.5) compare
Ga0059261_2326 -4.7 -7.1 Phosphohistidine phosphatase SixA compare
Ga0059261_2264 -4.6 -15.2 D-3-phosphoglycerate dehydrogenase compare
Ga0059261_2649 -4.5 -19.9 Dihydroxyacid dehydratase/phosphogluconate dehydratase conserved
Ga0059261_1500 -4.5 -5.3 phosphoadenylylsulfate reductase (thioredoxin) (EC 1.8.4.8) compare
Ga0059261_0351 -4.5 -11.5 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
Ga0059261_1797 -4.4 -16.6 glutamate synthase small subunit family protein, proteobacterial compare
Ga0059261_0067 -4.4 -10.6 acetolactate synthase, small subunit (EC 2.2.1.6) compare
Ga0059261_2035 -4.4 -10.8 Histidinol-phosphatase [alternative form] (EC 3.1.3.15) (from data) compare
Ga0059261_1896 -4.3 -11.5 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) (from data) conserved
Ga0059261_2052 -4.3 -7.1 siroheme synthase, N-terminal domain compare
Ga0059261_3196 -4.3 -4.1 Transcriptional regulator compare
Ga0059261_2298 -4.3 -12.5 prephenate and/or arogenate dehydrogenase (EC 1.3.1.13) (from data) compare
Ga0059261_0237 -4.2 -5.7 phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Ga0059261_1044 -4.2 -14.5 imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Ga0059261_2263 -4.2 -12.0 ATP phosphoribosyltransferase involved in histidine biosynthesis compare
Ga0059261_1800 -4.2 -28.0 Glutamate synthase domain 2 compare
Ga0059261_1893 -4.2 -16.5 Xylonolactonase (EC 3.1.1.68) (from data) conserved
Ga0059261_0256 -4.1 -14.1 anthranilate synthase component I, non-proteobacterial lineages compare
Ga0059261_2301 -4.1 -19.7 homoserine O-acetyltransferase (EC 2.3.1.31) compare
Ga0059261_3630 -4.1 -15.4 phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Ga0059261_0992 -4.1 -8.0 5,10-methylenetetrahydrofolate reductase, prokaryotic form compare
Ga0059261_2299 -4.1 -21.4 histidinol-phosphate aminotransferase compare
Ga0059261_2049 -4.0 -11.3 argininosuccinate lyase compare
Ga0059261_3206 -4.0 -9.4 ornithine carbamoyltransferase compare
Ga0059261_4216 -4.0 -15.9 Dihydroxyacid dehydratase/phosphogluconate dehydratase compare
Ga0059261_0068 -4.0 -12.7 acetolactate synthase, large subunit (EC 2.2.1.6) compare
Ga0059261_2226 -4.0 -21.1 Aspartate/tyrosine/aromatic aminotransferase compare
Ga0059261_2506 -4.0 -12.0 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) compare
Ga0059261_2514 -4.0 -17.4 phosphoenolpyruvate-protein phosphotransferase compare
Ga0059261_3169 -3.9 -8.1 phosphoglycerate mutase, BPG-dependent, family 1 compare
Ga0059261_0980 -3.9 -10.4 polyhydroxyalkanoate synthesis repressor PhaR compare
Ga0059261_1046 -3.9 -10.7 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
Ga0059261_4030 -3.9 -9.0 glutamate N-acetyltransferase (EC 2.3.1.35) compare
Ga0059261_1479 -3.9 -12.5 Lactate dehydrogenase and related dehydrogenases compare
Ga0059261_0929 -3.9 -8.3 anthranilate phosphoribosyltransferase compare
Ga0059261_4031 -3.9 -19.1 2-isopropylmalate synthase, yeast type compare
Ga0059261_1048 -3.9 -16.1 imidazoleglycerol phosphate synthase, cyclase subunit compare
Ga0059261_2269 -3.8 -16.9 Prephenate dehydratase compare
Ga0059261_4041 -3.8 -14.8 sulfate adenylyltransferase, large subunit compare
Ga0059261_3253 -3.8 -11.6 homoserine kinase (EC 2.7.1.39) (from data) compare
Ga0059261_3103 -3.7 -5.1 Glycosyltransferase compare
Ga0059261_1999 -3.7 -9.2 threonine synthase compare
Ga0059261_1498 -3.7 -12.7 Sulfite reductase, beta subunit (hemoprotein) compare
Ga0059261_3190 -3.7 -19.6 3-isopropylmalate dehydrogenase compare
Ga0059261_0918 -3.7 -7.0 Phosphotransferase system, mannose/fructose-specific component IIA compare
Ga0059261_1895 -3.7 -17.6 2-keto-3-deoxyxylonate dehydratase (EC 4.2.1.141) (from data) conserved
Ga0059261_3205 -3.6 -14.8 transaminase, acetylornithine/succinylornithine family compare
Ga0059261_4223 -3.6 -16.5 3-isopropylmalate dehydratase, large subunit compare
Ga0059261_0154 -3.6 -14.0 Predicted permeases compare
Ga0059261_4042 -3.6 -15.5 sulfate adenylyltransferase, small subunit compare
Ga0059261_2051 -3.6 -14.4 diaminopimelate decarboxylase (EC 4.1.1.20) (from data) compare
Ga0059261_3194 -3.6 -11.5 O-acetylhomoserine sulfhydrylase (EC:2.5.1.49) (from data) compare
Ga0059261_0990 -3.5 -18.8 methionine synthase (B12-dependent) (EC 2.1.1.13) compare
Ga0059261_2303 -3.5 -9.9 methionine biosynthesis protein MetW compare
Ga0059261_1986 -3.5 -9.0 Glycine/serine hydroxymethyltransferase compare
Ga0059261_2194 -3.5 -6.0 shikimate dehydrogenase (EC 1.1.1.25) (from data) compare
Ga0059261_1382 -3.5 -9.9 periplasmic serine protease, Do/DeqQ family compare
Ga0059261_0349 -3.4 -5.6 MarR family compare
Ga0059261_3191 -3.4 -9.6 Glycosyltransferases involved in cell wall biogenesis compare
Ga0059261_3811 -3.4 -15.6 branched-chain amino acid aminotransferase, group II compare
Ga0059261_0930 -3.4 -8.4 indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Ga0059261_2021 -3.4 -16.9 Protein of unknown function (DUF2029) compare
Ga0059261_3694 -3.4 -14.7 threonine deaminase (EC 4.3.1.19) (from data) compare
Ga0059261_1293 -3.4 -16.5 (p)ppGpp synthetase, RelA/SpoT family compare
Ga0059261_1499 -3.3 -6.3 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Ga0059261_1280 -3.3 -10.3 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Ga0059261_2295 -3.3 -5.6 DUF218 domain compare
Ga0059261_1051 -3.2 -11.2 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Ga0059261_3488 -3.2 -3.1 Histidine kinase/HAMP domain compare
Ga0059261_1047 -3.1 -5.7 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Ga0059261_2490 -3.1 -7.7 Small protein A (tmRNA-binding) compare
Ga0059261_2700 -3.1 -15.2 Putative Zn-dependent protease, contains TPR repeats compare
Ga0059261_0239 -3.1 -3.0 tryptophan synthase, alpha chain (EC 4.2.1.20) compare
Ga0059261_0893 -3.1 -6.2 inosine-5'-monophosphate dehydrogenase compare
Ga0059261_2711 -3.1 -6.7 homoserine dehydrogenase (EC 1.1.1.3) (from data) compare
Ga0059261_3512 -3.0 -3.4 glutamate 5-kinase (EC 2.7.2.11) (from data) compare
Ga0059261_2707 -3.0 -8.5 fructose-1,6-bisphosphatase, class II compare
Ga0059261_1360 -3.0 -13.2 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase compare
Ga0059261_0926 -2.9 -6.2 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Ga0059261_2179 -2.9 -11.9 Phospholipid N-methyltransferase compare
Ga0059261_1919 -2.9 -14.4 L,D-transpeptidase catalytic domain compare
Ga0059261_0991 -2.9 -11.1 Methionine synthase I (cobalamin-dependent), methyltransferase domain compare
Ga0059261_2928 -2.9 -7.6 oxygen-dependent methionine synthase, putative oxygenase component MesX (from data) compare
Ga0059261_3497 -2.9 -11.0 Membrane proteins related to metalloendopeptidases compare
Ga0059261_1869 -2.9 -7.8 ABC-type transport system involved in resistance to organic solvents, periplasmic component compare
Ga0059261_3101 -2.9 -5.4 nucleotide sugar dehydrogenase compare
Ga0059261_1496 -2.8 -5.5 uroporphyrin-III C-methyltransferase compare
Ga0059261_2132 -2.8 -4.6 transcriptional regulator, BadM/Rrf2 family compare
Ga0059261_3644 -2.8 -10.0 cysteine synthase A compare
Ga0059261_1507 -2.8 -3.8 deoxycytidine triphosphate deaminase compare
Ga0059261_0613 -2.8 -5.2 FecR family protein compare
Ga0059261_0274 -2.7 -7.4 transcriptional regulator, TraR/DksA family compare
Ga0059261_1190 -2.7 -7.1 hypothetical protein compare
Ga0059261_3236 -2.7 -17.3 pyruvate phosphate dikinase (EC 2.7.9.1) compare
Ga0059261_2243 -2.6 -3.6 Membrane protein involved in the export of O-antigen and teichoic acid compare
Ga0059261_1605 -2.6 -7.7 transcriptional regulator, TetR family compare
Ga0059261_1870 -2.6 -7.2 ABC-type transport system involved in resistance to organic solvents, ATPase component compare
Ga0059261_0163 -2.6 -4.2 Major Facilitator Superfamily compare
Ga0059261_1497 -2.6 -7.0 required for sulfate utilization, putative electron source for sulfite reductase CysI (from data) compare
Ga0059261_2481 -2.5 -7.5 Ppx/GppA phosphatase family compare
Ga0059261_1369 -2.5 -12.1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Ga0059261_0258 -2.5 -6.1 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase (EC 2.5.1.54) compare
Ga0059261_3159 -2.5 -6.0 TolR protein compare
Ga0059261_2190 -2.4 -4.1 PTS IIA-like nitrogen-regulatory protein PtsN compare
Ga0059261_1310 -2.4 -4.4 Predicted transcriptional regulators compare
Ga0059261_1868 -2.4 -4.1 ABC-type uncharacterized transport system, auxiliary component compare
Ga0059261_1871 -2.4 -10.6 ABC transport permease subunit compare
Ga0059261_1053 -2.3 -15.1 amino acid/polyamine/organocation transporter, APC superfamily (TC 2.A.3) compare
Ga0059261_2034 -2.3 -13.4 Uncharacterized protein conserved in bacteria compare
Ga0059261_1417 -2.3 -2.5 transcriptional regulator, XRE family compare
Ga0059261_1001 -2.3 -9.2 ATP-dependent Clp protease ATP-binding subunit ClpA (EC 3.4.21.92) compare
Ga0059261_3097 -2.3 -5.4 Calcineurin-like phosphoesterase compare
Ga0059261_2424 -2.2 -16.0 hydroxymethylpyrimidine synthase compare
Ga0059261_0102 -2.0 -10.7 endopeptidase La compare
Ga0059261_2498 -2.0 -5.8 hypothetical protein compare
Ga0059261_3786 -2.0 -6.9 Malic enzyme compare
Ga0059261_0767 -2.0 -13.0 glucose/galactose transporter compare
Ga0059261_1444 -2.0 -13.6 Outer membrane protein and related peptidoglycan-associated (lipo)proteins compare
Ga0059261_2980 -1.9 -15.1 Outer membrane protein compare
Ga0059261_2444 -1.9 -6.5 5-aminolevulinic acid synthase compare
Ga0059261_3160 -1.8 -4.7 TolQ protein compare
Ga0059261_2417 -1.8 -4.7 phytoene desaturase compare
Ga0059261_0725 -1.8 -4.2 Fructose-1,6-bisphosphate aldolase compare
Ga0059261_2314 -1.7 -3.6 Protein-disulfide isomerase compare
Ga0059261_2930 -1.7 -5.7 Predicted Na+-dependent transporter compare
Ga0059261_0197 -1.7 -2.0 hypothetical protein compare
Ga0059261_2013 -1.7 -10.5 signal peptidase I, bacterial type compare
Ga0059261_3153 -1.6 -2.8 Uncharacterized protein conserved in bacteria compare
Ga0059261_3255 -1.6 -7.7 hypothetical protein compare
Ga0059261_0153 -1.6 -2.8 Serine acetyltransferase compare
Ga0059261_2981 -1.6 -12.2 Uncharacterized protein conserved in bacteria compare
Ga0059261_0354 -1.6 -3.5 6-phosphogluconate dehydratase (EC 4.2.1.12) compare
Ga0059261_0255 -1.6 -2.7 SurA N-terminal domain/PPIC-type PPIASE domain compare
Ga0059261_3156 -1.6 -5.9 peptidoglycan-associated lipoprotein compare
Ga0059261_1545 -1.6 -5.2 Fe2+/Zn2+ uptake regulation proteins compare
Ga0059261_0181 -1.6 -7.4 Predicted membrane-associated Zn-dependent proteases 1 compare
Ga0059261_0735 -1.5 -6.8 5,10-methenyltetrahydrofolate synthetase compare
Ga0059261_2213 -1.5 -5.1 Domain of unknown function (DUF3576) compare
Ga0059261_2458 -1.5 -7.2 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases compare
Ga0059261_3157 -1.5 -9.8 tol-pal system beta propeller repeat protein TolB compare
Ga0059261_0474 -1.5 -11.0 cation diffusion facilitator family transporter compare
Ga0059261_0136 -1.5 -4.5 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation compare
Ga0059261_2618 -1.5 -4.2 Protein of unknown function (DUF2721) compare
Ga0059261_2929 -1.4 -2.5 oxygen-dependent methionine synthase, methyltransferase component MesD (from data) compare
Ga0059261_1313 -1.4 -12.1 acetyl-coenzyme A synthetase (EC 6.2.1.1) compare
Ga0059261_2191 -1.4 -7.9 ribosomal subunit interface protein compare
Ga0059261_1564 -1.4 -4.3 cytochrome bo3 quinol oxidase subunit 3 (EC 1.10.3.-) compare
Ga0059261_1573 -1.4 -5.6 hypothetical protein compare
Ga0059261_1388 -1.4 -10.1 cystathionine beta-lyase, bacterial compare
Ga0059261_1565 -1.3 -9.5 cytochrome bo3 quinol oxidase subunit 1 apoprotein (EC 1.10.3.-) compare
Ga0059261_3195 -1.2 -4.2 Uncharacterized protein affecting Mg2+/Co2+ transport compare
Ga0059261_1397 -1.2 -9.9 Cyclopropane fatty acid synthase and related methyltransferases compare
Ga0059261_1563 -1.2 -2.2 cytochrome bo3 quinol oxidase subunit 4 (EC 1.10.3.-) compare
Ga0059261_0555 -1.2 -8.9 transcriptional regulator, LacI family compare
Ga0059261_3896 -1.2 -2.9 integration host factor, beta subunit compare
Ga0059261_0246 -1.2 -1.8 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD compare
Ga0059261_2145 -1.2 -4.8 ribosome-binding factor A compare
Ga0059261_1821 -1.2 -8.2 formyltetrahydrofolate deformylase (EC 3.5.1.10) compare
Ga0059261_2662 -1.2 -8.7 Transcriptional regulators compare
Ga0059261_2260 -1.2 -7.8 TIGR01244 family protein compare
Ga0059261_3502 -1.1 -2.5 Fatty acid desaturase compare
Ga0059261_1799 -1.1 -0.7 Uncharacterized protein conserved in bacteria (DUF2059) compare
Ga0059261_3128 -1.1 -7.7 capsular exopolysaccharide family compare
Ga0059261_2680 -1.0 -1.6 hypothetical protein compare
Ga0059261_3345 -1.0 -2.3 TlyA family rRNA methyltransferase/putative hemolysin compare
Ga0059261_3130 -1.0 -5.4 Lipid A core - O-antigen ligase and related enzymes compare
Ga0059261_2324 -1.0 -4.5 integration host factor, alpha subunit compare
Ga0059261_1696 -1.0 -3.4 Pyridine nucleotide-disulphide oxidoreductase/Reductase C-terminal compare
Ga0059261_0620 -1.0 -8.4 Outer membrane cobalamin receptor protein compare
Ga0059261_1566 -1.0 -5.4 cytochrome o ubiquinol oxidase subunit II compare
Ga0059261_1638 -1.0 -4.3 transcriptional regulator, GntR family compare
Ga0059261_4044 -1.0 -4.3 FOG: EAL domain compare
Ga0059261_0889 -1.0 -2.4 Cold shock proteins compare
Ga0059261_3211 -1.0 -6.1 hypothetical protein compare
Ga0059261_1798 -1.0 -3.7 Uncharacterized protein conserved in bacteria (DUF2059) compare
Ga0059261_0827 -1.0 -2.6 hypothetical protein compare
Ga0059261_2543 -1.0 -8.1 RNA polymerase, sigma 54 subunit, RpoN/SigL compare
Ga0059261_0817 -1.0 -4.7 GTP-binding protein TypA/BipA compare
Ga0059261_2283 -1.0 -5.2 Predicted membrane protein compare
Ga0059261_2739 -1.0 -4.4 heat-inducible transcription repressor HrcA compare
Ga0059261_0623 -1.0 -3.7 ABC-type Fe3+-siderophore transport system, permease component compare
Ga0059261_2196 -1.0 -6.2 Uncharacterized protein conserved in bacteria compare
Ga0059261_0624 -1.0 -5.3 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components compare
Ga0059261_3129 -1.0 -5.6 SLBB domain/Polysaccharide biosynthesis/export protein compare
Ga0059261_2205 -0.9 -7.3 glucose-inhibited division protein A compare
Ga0059261_1517 -0.9 -4.5 Predicted acetyltransferase compare
Ga0059261_1351 -0.9 -6.4 signal peptide peptidase SppA, 67K type compare
Ga0059261_1611 -0.9 -6.7 Glucose/sorbosone dehydrogenases compare
Ga0059261_2204 -0.9 -5.9 tRNA modification GTPase trmE compare
Ga0059261_3277 -0.9 -6.4 polyhydroxyalkanoate depolymerase, intracellular compare
Ga0059261_3493 -0.9 -3.5 hypothetical protein compare


Specific Phenotypes

For 7 genes in this experiment

For carbon source D-Xylose in Sphingomonas koreensis DSMZ 15582

For carbon source D-Xylose across organisms