Experiment set3IT074 for Pseudomonas fluorescens FW300-N2E2

Compare to:

LB with 5-Hydroxymethylfurfural 10 mM

200 most detrimental genes:

  gene name fitness t score description  
Pf6N2E2_825 +5.1 41.0 Multidrug efflux membrane fusion protein MexE compare
Pf6N2E2_1055 +5.0 40.1 Transcriptional regulator MexT compare
Pf6N2E2_824 +5.0 45.2 Multidrug efflux transporter MexF compare
Pf6N2E2_5481 +4.2 34.4 Transcriptional regulator, AraC family compare
Pf6N2E2_5482 +4.0 29.1 FIG00954888: hypothetical protein compare
Pf6N2E2_823 +3.4 28.7 Outer membrane protein OprN compare
Pf6N2E2_2280 +2.6 23.4 COG0553: Superfamily II DNA/RNA helicases, SNF2 family compare
Pf6N2E2_4150 +2.3 14.4 probable exported protein YPO0432 compare
Pf6N2E2_3942 +2.3 18.8 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
Pf6N2E2_4152 +2.3 17.4 alginate biosynthesis transcriptional regulatory protein AlgB compare
Pf6N2E2_2279 +2.2 8.6 FIG00954981: hypothetical protein compare
Pf6N2E2_813 +2.1 12.2 Response regulator compare
Pf6N2E2_2756 +2.1 14.3 RNA polymerase sigma-H factor AlgT compare
Pf6N2E2_5483 +1.9 8.1 hypothetical protein compare
Pf6N2E2_5720 +1.7 15.5 BarA sensory histidine kinase (= VarS = GacS) compare
Pf6N2E2_2022 +1.7 12.4 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf6N2E2_3062 +1.6 8.6 Membrane-associated zinc metalloprotease compare
Pf6N2E2_5160 +1.6 6.8 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_3271 +1.4 4.6 Phosphocarrier protein, nitrogen regulation associated compare
Pf6N2E2_5534 +1.2 7.2 FIG000859: hypothetical protein YebC compare
Pf6N2E2_819 +1.1 4.2 Response regulator compare
Pf6N2E2_3480 +1.1 3.3 Transcriptional regulator, ArsR family compare
Pf6N2E2_5255 +1.1 8.8 Outer membrane stress sensor protease DegS compare
Pf6N2E2_923 +1.0 2.5 Haloacid dehalogenase, type II (EC 3.8.1.2) compare
Pf6N2E2_3672 +1.0 7.2 Glutamate-ammonia-ligase adenylyltransferase (EC 2.7.7.42) compare
Pf6N2E2_831 +1.0 1.5 Ketoacyl reductase hetN (EC 1.3.1.-) compare
Pf6N2E2_2727 +1.0 6.9 Ribonuclease D (EC 3.1.26.3) compare
Pf6N2E2_3349 +1.0 2.5 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_1918 +1.0 5.4 Major facilitator family transporter compare
Pf6N2E2_5780 +1.0 7.3 Periplasmic protease compare
Pf6N2E2_818 +1.0 5.1 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
Pf6N2E2_5714 +1.0 2.0 Flavoprotein WrbA compare
Pf6N2E2_2693 +0.9 2.1 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
Pf6N2E2_2674 +0.9 1.7 FIG00953856: hypothetical protein compare
Pf6N2E2_4732 +0.9 2.5 hypothetical protein compare
Pf6N2E2_1981 +0.9 5.3 FIG051360: Periplasmic protein TonB, links inner and outer membranes compare
Pf6N2E2_2084 +0.9 6.7 sensory box histidine kinase/response regulator compare
Pf6N2E2_4077 +0.9 1.3 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf6N2E2_615 +0.9 4.8 FIG00957600: hypothetical protein compare
Pf6N2E2_815 +0.9 6.2 Signal transduction histidine kinase compare
Pf6N2E2_4543 +0.9 4.0 hypothetical protein compare
Pf6N2E2_816 +0.8 5.2 Chemotaxis protein methyltransferase CheR (EC 2.1.1.80) compare
Pf6N2E2_5704 +0.8 5.0 Transcriptional regulatory protein PhoP compare
Pf6N2E2_2367 +0.8 1.2 hypothetical protein compare
Pf6N2E2_546 +0.8 1.7 FIG00966904: hypothetical protein compare
Pf6N2E2_5869 +0.8 2.7 Helicase subunit of the DNA excision repair complex compare
Pf6N2E2_6044 +0.8 6.1 Sensor histidine kinase/response regulator compare
Pf6N2E2_3338 +0.8 1.7 1-phosphofructokinase (EC 2.7.1.56) compare
Pf6N2E2_3264 +0.8 1.6 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_4494 +0.8 1.0 Adenylate cyclase (EC 4.6.1.1) compare
Pf6N2E2_2438 +0.7 2.3 hypothetical protein compare
Pf6N2E2_3261 +0.7 2.8 hypothetical protein compare
Pf6N2E2_2106 +0.7 2.0 hypothetical protein compare
Pf6N2E2_942 +0.7 1.6 Mll6465 protein compare
Pf6N2E2_2748 +0.7 5.2 Glycine cleavage system transcriptional antiactivator GcvR compare
Pf6N2E2_5766 +0.7 1.0 Quaternary ammonium compound-resistance protein SugE compare
Pf6N2E2_3761 +0.7 6.4 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) compare
Pf6N2E2_5730 +0.7 1.5 FIG00954480: hypothetical protein compare
Pf6N2E2_1288 +0.7 1.9 Protein containing transglutaminase-like domain, putative cysteine protease compare
Pf6N2E2_5825 +0.7 3.4 FIG00958237: hypothetical protein compare
Pf6N2E2_3835 +0.7 2.5 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_639 +0.7 1.6 FIG01285020: hypothetical protein compare
Pf6N2E2_5987 +0.7 4.1 OmpA family protein compare
Pf6N2E2_1085 +0.7 2.1 Fe2+/Zn2+ uptake regulation proteins compare
Pf6N2E2_237 +0.7 1.8 hypothetical protein compare
Pf6N2E2_2013 +0.7 1.3 hypothetical protein compare
Pf6N2E2_822 +0.7 3.5 TPR domain protein compare
Pf6N2E2_4541 +0.7 1.4 hypothetical protein compare
Pf6N2E2_4579 +0.6 0.8 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_968 +0.6 2.6 FIG00962395: hypothetical protein compare
Pf6N2E2_1294 +0.6 0.7 Carbon starvation protein A compare
Pf6N2E2_463 +0.6 2.7 Transcriptional regulatory protein RstA compare
Pf6N2E2_6070 +0.6 1.6 FIG137877: Hypothetical protein in pyoverdin gene cluster compare
Pf6N2E2_1906 +0.6 4.2 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf6N2E2_5768 +0.6 2.9 DNA recombination-dependent growth factor C compare
Pf6N2E2_226 +0.6 2.9 2,3-dihydroxybiphenyl 1,2-dioxygenase compare
Pf6N2E2_2912 +0.6 1.4 FIG00954094: hypothetical protein compare
Pf6N2E2_2471 +0.6 4.5 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_4423 +0.6 1.7 FIG00953342: hypothetical protein compare
Pf6N2E2_4317 +0.6 2.7 FIG00964469: hypothetical protein compare
Pf6N2E2_3095 +0.6 1.1 hypothetical protein compare
Pf6N2E2_443 +0.6 2.5 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_6113 +0.6 2.6 tRNA-Gly-CCC compare
Pf6N2E2_367 +0.6 2.3 Acetylornithine deacetylase (EC 3.5.1.16) compare
Pf6N2E2_1932 +0.6 2.8 Transcriptional regulator, IclR family compare
Pf6N2E2_2973 +0.6 3.2 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_5400 +0.6 4.8 ATP-dependent RNA helicase RhlB compare
Pf6N2E2_1438 +0.6 2.9 Methyltransferase (EC 2.1.1.-) compare
Pf6N2E2_2406 +0.6 3.8 Periplasmic binding protein compare
Pf6N2E2_5902 +0.6 2.4 hypothetical protein compare
Pf6N2E2_703 +0.6 2.4 Cytochrome c55X precursor NirC compare
Pf6N2E2_5499 +0.6 1.0 hypothetical protein compare
Pf6N2E2_3379 +0.6 4.5 Lactate-responsive regulator LldR in Enterobacteria, GntR family compare
Pf6N2E2_3870 +0.6 1.4 hypothetical protein compare
Pf6N2E2_5103 +0.6 0.8 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_5722 +0.6 1.5 23S rRNA (Uracil-5-) -methyltransferase RumA (EC 2.1.1.-) ## LSU rRNA m(5)U1939 compare
Pf6N2E2_3640 +0.5 3.4 FIG074102: hypothetical protein compare
Pf6N2E2_1545 +0.5 2.3 N-carbamoylputrescine amidase (EC 3.5.1.53) compare
Pf6N2E2_3569 +0.5 1.4 hypothetical protein compare
Pf6N2E2_3613 +0.5 3.8 GTP-binding protein HflX compare
Pf6N2E2_180 +0.5 1.6 Transcriptional regulator, MerR family compare
Pf6N2E2_5621 +0.5 2.7 DNA-binding response regulator compare
Pf6N2E2_1676 +0.5 0.9 conserved protein associated with acetyl-CoA C-acyltransferase compare
Pf6N2E2_5278 +0.5 3.6 Signal transduction histidine kinase compare
Pf6N2E2_1706 +0.5 1.5 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) compare
Pf6N2E2_3763 +0.5 1.9 hypothetical protein compare
Pf6N2E2_817 +0.5 2.2 Protein-glutamate methylesterase (EC 3.1.1.61) compare
Pf6N2E2_5687 +0.5 3.6 Transporter, MFS superfamily compare
Pf6N2E2_5841 +0.5 1.0 GlcG protein compare
Pf6N2E2_2519 +0.5 1.1 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) compare
Pf6N2E2_3311 +0.5 3.0 Dipeptide transport system permease protein DppB (TC 3.A.1.5.2) compare
Pf6N2E2_1028 +0.5 1.7 Transcriptional regulator, LysR family compare
Pf6N2E2_4992 +0.5 4.7 DNA-3-methyladenine glycosylase II (EC 3.2.2.21) compare
Pf6N2E2_605 +0.5 1.5 FIG002465: BNR repeat protein compare
Pf6N2E2_4485 +0.5 4.1 Aminomethyltransferase (glycine cleavage system T protein) (EC 2.1.2.10) compare
Pf6N2E2_5965 +0.5 2.0 transcriptional regulator compare
Pf6N2E2_1444 +0.5 2.0 Transcriptional regulator, LysR family compare
Pf6N2E2_3568 +0.5 1.1 Unsaturated fatty acid biosythesis repressor FabR, TetR family compare
Pf6N2E2_1907 +0.5 2.8 Choline dehydrogenase (EC 1.1.99.1) compare
Pf6N2E2_5991 +0.5 1.7 proteinase inhibitor compare
Pf6N2E2_3720 +0.5 1.5 FIG027190: Putative transmembrane protein compare
Pf6N2E2_3844 +0.5 1.5 hypothetical protein compare
Pf6N2E2_5024 +0.5 2.0 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) compare
Pf6N2E2_5240 +0.5 2.6 FIG00953775: hypothetical protein compare
Pf6N2E2_1837 +0.5 1.7 Hydroxymethylglutaryl-CoA synthase (EC 2.3.3.10) compare
Pf6N2E2_5025 +0.5 4.6 Sensor histidine kinase compare
Pf6N2E2_88 +0.5 1.5 hypothetical protein compare
Pf6N2E2_2466 +0.5 3.5 Universal stress protein family compare
Pf6N2E2_1040 +0.5 1.1 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_373 +0.5 2.3 Gamma-aminobutyrate:alpha-ketoglutarate aminotransferase (EC 2.6.1.19) compare
Pf6N2E2_1293 +0.5 1.9 COG2879, Hypothetical small protein yjiX compare
Pf6N2E2_2964 +0.5 1.5 FIG006285: ICC-like protein phosphoesterase compare
Pf6N2E2_2717 +0.5 2.1 putative cytoplasmic protein compare
Pf6N2E2_4609 +0.5 1.5 UPF0301 protein YqgE compare
Pf6N2E2_814 +0.5 1.5 hypothetical protein compare
Pf6N2E2_4635 +0.5 2.3 ATP-dependent RNA helicase RhlE compare
Pf6N2E2_3183 +0.5 1.0 Believed to be involved in assembly of Fe-S clusters compare
Pf6N2E2_2121 +0.5 1.0 hypothetical protein compare
Pf6N2E2_5772 +0.5 1.7 DUF1232 domain-containing protein compare
Pf6N2E2_3100 +0.5 1.6 FIG00953063: hypothetical protein compare
Pf6N2E2_1140 +0.4 1.1 Polymyxin resistance protein ArnC, glycosyl transferase (EC 2.4.-.-) compare
Pf6N2E2_3237 +0.4 1.3 hypothetical protein compare
Pf6N2E2_2860 +0.4 1.6 Putative threonine efflux protein compare
Pf6N2E2_2080 +0.4 0.8 hypothetical protein compare
Pf6N2E2_2544 +0.4 1.4 Deblocking aminopeptidase (EC 3.4.11.-) @ Cyanophycinase 2 (EC 3.4.15.6) compare
Pf6N2E2_1775 +0.4 1.9 Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) compare
Pf6N2E2_2469 +0.4 2.2 hypothetical protein compare
Pf6N2E2_2039 +0.4 2.7 Sigma-54 dependent transcriptional regulator compare
Pf6N2E2_5030 +0.4 2.1 Transcriptional regulator, AsnC family compare
Pf6N2E2_1236 +0.4 1.6 Transcriptional regulator, LysR family compare
Pf6N2E2_5344 +0.4 2.2 Predicted endonuclease distantly related to archaeal Holliday junction resolvase compare
Pf6N2E2_4052 +0.4 1.1 FIG00955481: hypothetical protein compare
Pf6N2E2_1784 +0.4 1.1 Methyl-accepting chemotaxis protein compare
Pf6N2E2_5919 +0.4 1.2 Flp pilus assembly protein TadD, contains TPR repeats compare
Pf6N2E2_826 +0.4 1.7 ABC-type amino acid transport, signal transduction systems, periplasmic component/domain compare
Pf6N2E2_2824 +0.4 3.2 RND efflux system, inner membrane transporter CmeB compare
Pf6N2E2_638 +0.4 1.7 4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein compare
Pf6N2E2_4721 +0.4 1.7 Sarcosine oxidase gamma subunit (EC 1.5.3.1) compare
Pf6N2E2_4453 +0.4 3.8 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_719 +0.4 1.1 Molybdenum cofactor biosynthesis protein MoaB compare
Pf6N2E2_3314 +0.4 3.4 Dipeptide transport ATP-binding protein DppF (TC 3.A.1.5.2) compare
Pf6N2E2_282 +0.4 0.8 GNAT family acetyltransferase YjcF compare
Pf6N2E2_509 +0.4 1.8 Glutathione S-transferase, unnamed subgroup 2 (EC 2.5.1.18) compare
Pf6N2E2_5776 +0.4 1.1 hypothetical protein compare
Pf6N2E2_5219 +0.4 2.8 FIG140336: TPR domain protein compare
Pf6N2E2_2794 +0.4 0.9 putative membrane protein compare
Pf6N2E2_328 +0.4 1.6 hypothetical protein compare
Pf6N2E2_3156 +0.4 2.3 POSSIBLE MEMBRANE PROTEIN compare
Pf6N2E2_1584 +0.4 1.0 Transcriptional regulator, MarR family / Acetyltransferase (GNAT) compare
Pf6N2E2_1115 +0.4 1.9 Nitrite reductase [NAD(P)H] small subunit (EC 1.7.1.4) compare
Pf6N2E2_1885 +0.4 1.7 Transcriptional regulator, AraC family compare
Pf6N2E2_4478 +0.4 2.8 FIG019278: hypothetical protein compare
Pf6N2E2_5963 +0.4 1.3 lipoprotein, putative compare
Pf6N2E2_2536 +0.4 1.0 Fumarate hydratase class II (EC 4.2.1.2) compare
Pf6N2E2_3471 +0.4 1.8 transcriptional regulator, MerR family compare
Pf6N2E2_1667 +0.4 1.2 Fumarylacetoacetate hydrolase family protein compare
Pf6N2E2_3876 +0.4 1.4 Agmatine deiminase (EC 3.5.3.12) compare
Pf6N2E2_2175 +0.4 2.1 Transcriptional regulator, RpiR family compare
Pf6N2E2_2285 +0.4 0.8 FIG00954079: hypothetical protein compare
Pf6N2E2_3975 +0.4 1.4 Taurine transport ATP-binding protein TauB compare
Pf6N2E2_1036 +0.4 1.9 Biopolymer transport protein ExbD/TolR compare
Pf6N2E2_4378 +0.4 3.3 Dipeptide-binding ABC transporter, periplasmic substrate-binding component (TC 3.A.1.5.2) compare
Pf6N2E2_3312 +0.4 2.1 Dipeptide transport system permease protein DppC (TC 3.A.1.5.2) compare
Pf6N2E2_350 +0.4 1.0 Gfa-like protein compare
Pf6N2E2_4307 +0.4 1.3 Type VI secretion lipoprotein/VasD compare
Pf6N2E2_1083 +0.4 1.0 hypothetical protein compare
Pf6N2E2_5104 +0.4 2.1 Conserved uncharacterized protein CreA compare
Pf6N2E2_3770 +0.4 1.0 ATP-dependent hsl protease ATP-binding subunit HslU compare
Pf6N2E2_2798 +0.4 2.1 Death on curing protein, Doc toxin compare
Pf6N2E2_2459 +0.4 1.2 Organic hydroperoxide resistance protein compare
Pf6N2E2_4662 +0.4 2.2 hypothetical protein compare
Pf6N2E2_2722 +0.4 2.0 FIG00954807: hypothetical protein compare
Pf6N2E2_757 +0.4 2.1 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) compare
Pf6N2E2_4331 +0.4 1.8 hypothetical protein compare
Pf6N2E2_1490 +0.4 0.5 hypothetical protein compare
Pf6N2E2_1755 +0.4 2.1 2-Oxobutyrate oxidase, putative compare
Pf6N2E2_2509 +0.4 0.6 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf6N2E2_2849 +0.4 1.5 Chromosome initiation inhibitor compare
Pf6N2E2_1211 +0.4 1.0 Lactoylglutathione lyase compare
Pf6N2E2_6040 +0.4 1.3 hypothetical protein compare


Specific Phenotypes

For 14 genes in this experiment

For stress 5-Hydroxymethylfurfural in Pseudomonas fluorescens FW300-N2E2

For stress 5-Hydroxymethylfurfural across organisms