Experiment set3IT063 for Caulobacter crescentus NA1000

Compare to:

PYE with Doxycycline hyclate 0.0001 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
CCNA_02387 +8.6 67.0 glutathione reductase compare
CCNA_00011 +7.6 35.8 chaperone protein DnaJ compare
CCNA_00769 +6.9 24.9 TetR family transcriptional regulator compare
CCNA_03577 +4.6 28.0 DNA polymerase I compare
CCNA_00852 +4.6 8.9 TetR family transcriptional regulator compare
CCNA_01059 +4.4 12.6 S-layer protein rsaA compare
CCNA_00768 +4.3 9.7 hypothetical protein compare
CCNA_02127 +3.8 22.8 oxacillin resistance-associated protein fmtC compare
CCNA_01060 +3.8 16.5 type I protein secretion ATP-binding protein RsaD compare
CCNA_01979 +3.7 15.0 LexA repressor compare
CCNA_00684 +3.7 29.5 anti-sigma factor, ChrR-family compare
CCNA_03936 +3.6 10.5 hypothetical protein compare
CCNA_03858 +3.6 22.9 protein translocase subunit secB compare
CCNA_01237 +3.5 1.9 hypothetical protein compare
CCNA_01815 +3.5 25.1 nitrogen assimilation regulatory protein NtrC compare
CCNA_01061 +3.4 13.2 type I secretion adaptor protein RsaE compare
CCNA_00389 +3.1 4.7 aminomethyltransferase family protein compare
CCNA_00527 +3.1 17.4 hypothetical protein compare
CCNA_01968 +3.1 12.8 pentapeptide repeats containing protein compare
CCNA_03702 +3.1 2.9 SSU ribosomal protein S1P compare
CCNA_00257 +3.0 12.8 adenosylhomocysteinase compare
CCNA_00999 +3.0 12.1 PAS-family motility and cell cycle regulatory protein MopJ compare
CCNA_03681 +3.0 19.2 ABC transporter ATP-binding protein compare
CCNA_02037 +3.0 17.3 ATP-dependent endopeptidase Lon compare
CCNA_03612 +3.0 18.2 HTH XRE-family transcriptional regulator compare
CCNA_03030 +2.9 19.2 cytochrome c2 compare
CCNA_03680 +2.9 25.8 aminopeptidase N compare
CCNA_01553 +2.9 15.2 undecaprenyl-phosphate beta-N-acetyl-D-fucosaminephosphotransferase compare
CCNA_01420 +2.9 13.1 NrdR family transcriptional regulator compare
CCNA_01722 +2.9 5.7 hypothetical protein compare
CCNA_00670 +2.9 10.3 ABC-type polysaccharide/polyol phosphate transport system, ATPase component compare
CCNA_01525 +2.8 14.7 flagellar biosynthesis repressor flbT compare
CCNA_03519 +2.8 23.1 PadR-family transcriptional regulator compare
CCNA_02646 +2.8 5.8 cell division protein MraZ compare
CCNA_02644 +2.7 10.4 cell division protein FtsL compare
CCNA_02448 +2.7 12.4 hypothetical protein compare
CCNA_00497 +2.7 16.5 putative rhamnosyl transferase compare
CCNA_02030 +2.7 10.6 hypothetical protein compare
CCNA_02026 +2.7 18.4 hypothetical protein compare
CCNA_01712 +2.7 21.7 CopY/TcrY family transcriptional repressor compare
CCNA_02000 +2.6 7.0 SSU ribosomal protein S2P compare
CCNA_01521 +2.6 16.4 hypothetical protein compare
CCNA_01751 +2.6 9.4 aminodeoxychorismate lyase compare
CCNA_03498 +2.6 20.0 MarR-family transcriptional regulator compare
CCNA_03643 +2.6 4.8 succinate dehydrogenase membrane anchor subunit compare
CCNA_01618 +2.5 9.5 uracil-DNA glycosylase compare
CCNA_03043 +2.5 10.5 type IV pilin protein pilA compare
CCNA_02980 +2.5 17.5 tryptophan 2,3-dioxygenase compare
CCNA_01814 +2.5 18.7 nitrogen regulation protein ntrB compare
CCNA_02866 +2.5 10.0 hypothetical protein compare
CCNA_00669 +2.5 20.0 glycosyltransferase family 99 protein WbsX compare
CCNA_01058 +2.5 14.3 helix-turn-helix transcriptional regulator compare
CCNA_00362 +2.5 9.9 zinc uptake regulation protein compare
CCNA_03748 +2.5 15.8 dTDP-4-dehydrorhamnose 3,5-epimerase compare
CCNA_00699 +2.5 15.0 LSU ribosomal protein L28P compare
CCNA_01433 +2.5 8.9 integration host factor alpha-subunit compare
CCNA_00163 +2.4 15.5 exopolysaccharide transport family protein compare
CCNA_03064 +2.4 10.0 PadR-family transcriptional regulator compare
CCNA_01526 +2.4 9.1 flagellar biosynthesis regulatory protein flaF compare
CCNA_00471 +2.4 15.3 GDP-L-fucose synthase compare
CCNA_01801 +2.4 10.4 hypothetical protein compare
CCNA_02289 +2.4 18.0 MarR/EmrR family transcriptional regulator compare
CCNA_02416 +2.4 15.2 DNA-binding protein HU compare
CCNA_00518 +2.3 11.5 LSU ribosomal protein L25P compare
CCNA_01199 +2.3 13.7 glucose-1-phosphate thymidylyltransferase compare
CCNA_02957 +2.3 9.2 ArsR-family transcriptional regulator compare
CCNA_03354 +2.3 9.9 5-formyltetrahydrofolate cyclo-ligase compare
CCNA_03949 +2.3 11.0 hypothetical protein compare
CCNA_00027 +2.3 4.9 2OG-Fe(II) oxygenase compare
CCNA_00375 +2.3 9.3 hypothetical protein compare
CCNA_01583 +2.2 6.2 phosphate-binding protein compare
CCNA_00168 +2.2 16.9 polysaccharide export protein compare
CCNA_00028 +2.2 8.5 TonB-dependent receptor compare
CCNA_00505 +2.2 11.1 ubiquinol-cytochrome c reductase iron-sulfur subunit compare
CCNA_01063 +2.2 12.0 UDP-perosamine 4-acetyl transferase compare
CCNA_02103 +2.2 13.6 hypothetical protein compare
CCNA_00013 +2.2 19.5 protein-PII uridylyltransferase compare
CCNA_03289 +2.1 7.9 HicB-family RNA-binding protein compare
CCNA_02347 +2.1 15.0 phosphomannomutase/phosphoglucomutase compare
CCNA_03805 +2.1 8.6 PadR-family transcriptional regulator compare
CCNA_01393 +2.1 16.3 soluble lytic murein transglycosylase compare
CCNA_01094 +2.1 5.7 hypothetical protein compare
CCNA_03129 +2.1 14.8 peptidoglycan-specific endopeptidase, M23 family compare
CCNA_02339 +2.1 14.6 methyltransferase compare
CCNA_03689 +2.1 15.0 alanine dehydrogenase compare
CCNA_01324 +2.1 6.5 LSU ribosomal protein L30P compare
CCNA_00161 +2.1 13.9 hypothetical protein compare
CCNA_03012 +2.1 8.9 peroxiredoxin compare
CCNA_03287 +2.1 16.0 PadR-family transcriptional regulator compare
CCNA_02225 +2.1 14.9 ArsR family/SAM-dependent transcriptional regulator compare
CCNA_03808 +2.0 14.9 organic solvent resistance transport system Ttg2C protein compare
CCNA_00164 +2.0 14.5 O-antigen polymerase compare
CCNA_03252 +2.0 15.5 CopY/TcrY-family transcriptional regulator compare
CCNA_03959 +2.0 1.9 hypothetical protein compare
CCNA_02732 +2.0 6.9 hypothetical protein compare
CCNA_01742 +2.0 10.1 hypothetical protein compare
CCNA_00149 +2.0 6.2 Cro/CI-family transcriptional regulator compare
CCNA_03271 +2.0 15.2 methionine gamma-lyase compare
CCNA_01790 +2.0 7.9 protein translocase subunit secG compare
CCNA_03733 +2.0 13.8 mannose-1-phosphate guanylyltransferase compare
CCNA_01181 +2.0 11.4 hypothetical protein compare
CCNA_02098 +2.0 13.6 molybdopterin-guanine dinucleotide biosynthesis protein A compare
CCNA_03273 +2.0 12.9 hypothetical protein compare
CCNA_00847 +2.0 11.6 leucine-responsive regulatory protein compare
CCNA_02021 +2.0 8.4 hypothetical protein compare
CCNA_01065 +2.0 12.2 glycosyltransferase compare
CCNA_01066 +2.0 14.0 glycosyltransferase compare
CCNA_03104 +2.0 11.3 3-dehydroquinate synthase compare
CCNA_01453 +2.0 9.3 electron transport complex I subunit, NADH-ubiquinone oxidoreductase compare
CCNA_03989 +2.0 15.8 MarR-family HTH transcriptional regulator / N-acyltransferase compare
CCNA_01942 +2.0 11.3 Rrf2 family protein compare
CCNA_01684 +2.0 11.8 phenylalanine-4-hydroxylase compare
CCNA_02025 +1.9 8.4 hypothetical protein compare
CCNA_01186 +1.9 10.4 hypothetical protein compare
CCNA_03893 +1.9 5.5 hypothetical protein compare
CCNA_01840 +1.9 15.5 MerR-family transcriptional regulator compare
CCNA_01242 +1.9 14.4 amino acid permease compare
CCNA_03961 +1.9 8.9 hypothetical protein compare
CCNA_R0037 +1.9 8.2 tRNA-Glu compare
CCNA_01064 +1.9 12.1 perosamine synthetase compare
CCNA_03479 +1.9 11.7 MarR-family transcriptional regulator compare
CCNA_01295 +1.9 12.2 integral membrane protein compare
CCNA_01931 +1.9 13.3 TetR-family transcriptional regulator compare
CCNA_01573 +1.9 10.9 ArsR-family transcriptional regulator compare
CCNA_R0026 +1.9 2.8 tRNA-Gly compare
CCNA_02252 +1.9 5.5 methylcrotonyl-CoA carboxylase carboxyl transferase subunit compare
CCNA_03832 +1.9 9.6 TetR-family transcriptional regulator compare
CCNA_02447 +1.9 11.4 PspA/IM30 family regulatory protein compare
CCNA_03062 +1.8 12.0 cell wall hydrolase family protein compare
CCNA_03464 +1.8 9.3 glycine cleavage system H protein compare
CCNA_03938 +1.8 6.8 hypothetical protein compare
CCNA_01235 +1.8 11.1 AcrR-family transcriptional regulator compare
CCNA_01804 +1.8 12.0 glutathione peroxidase compare
CCNA_01068 +1.8 15.8 glycosyltransferase compare
CCNA_00920 +1.8 5.4 hypothetical protein compare
CCNA_03391 +1.8 11.3 Cro/CI family transcriptional regulator compare
CCNA_03807 +1.8 11.5 organic solvent resistance transport system Ttg2D protein compare
CCNA_00047 +1.8 11.8 tRNA m7-G46 methyltransferase compare
CCNA_03518 +1.8 14.2 cytochrome c oxidase polypeptide II coxB compare
CCNA_00043 +1.8 6.8 N utilization substance protein A NusA compare
CCNA_02133 +1.8 8.2 glucokinase compare
CCNA_00939 +1.8 8.1 MarR-family transcriptional regulator compare
CCNA_01913 +1.8 12.5 MarR-family transcriptional regulator compare
CCNA_01964 +1.8 3.2 NADH dehydrogenase compare
CCNA_02617 +1.8 14.8 histidinol-phosphate aminotransferase compare
CCNA_03863 +1.8 5.4 hypothetical protein compare
CCNA_R0054 +1.8 3.4 tRNA-Gly compare
CCNA_01959 +1.8 4.7 3-dehydroquinate dehydratase compare
CCNA_01677 +1.8 9.5 carboxypeptidase G2 precursor compare
CCNA_00447 +1.8 11.0 chemotaxis protein cheD compare
CCNA_03123 +1.8 12.9 ArsR-family transcriptional regulator compare
CCNA_00101 +1.8 11.7 16S rRNA m5C methyltransferase RsmB conserved
CCNA_01593 +1.8 10.9 Xaa-pro aminopeptidase compare
CCNA_00803 +1.8 7.7 chemotaxis protein cheW compare
CCNA_03747 +1.7 9.7 glycosyltransferase compare
CCNA_03325 +1.7 8.2 hypothetical protein compare
CCNA_01780 +1.7 12.6 exopolyphosphatase compare
CCNA_01055 +1.7 11.4 GT1 family glyscosyl transferase compare
CCNA_01728 +1.7 8.9 short chain dehydrogenase compare
CCNA_00044 +1.7 7.5 ribosome maturation protein RimP compare
CCNA_01008 +1.7 13.4 urocanate hydratase compare
CCNA_01771 +1.7 1.8 hypothetical protein compare
CCNA_03316 +1.7 12.7 UDP-N-acetylglucosamine 4,6-dehydratase/UDP-D-quinovosamine 4-dehydrogenase compare
CCNA_00944 +1.7 10.2 flagellar hook length determination protein compare
CCNA_00924 +1.7 8.3 MarR/EmrR family transcriptional regulator compare
CCNA_02616 +1.7 12.1 4-hydroxyphenylpyruvate dioxygenase compare
CCNA_03513 +1.7 9.7 cytochrome c oxidase subunit III coxC compare
CCNA_00667 +1.7 9.5 lipopolysaccharide biosynthesis protein compare
CCNA_00148 +1.7 8.8 hypothetical protein compare
CCNA_02242 +1.7 11.2 PHB granule-associated protein, phasin2 compare
CCNA_01528 +1.7 10.8 flagellin fljK compare
CCNA_01415 +1.7 12.6 methyltransferase compare
CCNA_02073 +1.7 6.5 cupin domain transcriptional regulator compare
CCNA_00872 +1.7 6.1 glutaredoxin compare
CCNA_01141 +1.7 9.9 RecA protein compare
CCNA_02942 +1.7 5.1 nucleoside-diphosphate-sugar epimerase compare
CCNA_00947 +1.7 13.5 flagellar hook protein FlgE compare
CCNA_00441 +1.7 9.6 chemotaxis receiver domain protein cheYI compare
CCNA_00036 +1.7 2.3 ribosome-binding factor A compare
CCNA_00167 +1.6 10.4 metallophosphatase family protein compare
CCNA_00392 +1.6 12.5 dihydroorotase compare
CCNA_03280 +1.6 14.8 pyruvate ferredoxin/flavodoxin oxidoreductase family protein compare
CCNA_02063 +1.6 6.7 beta-barrel assembly machine (BAM) protein BamD compare
CCNA_02576 +1.6 12.9 phosphoribosylamidoimidazole-succinocarboxamide synthase compare
CCNA_00322 +1.6 11.2 hypothetical protein compare
CCNA_02619 +1.6 12.2 stomatin/prohibitin-related protein compare
CCNA_02164 +1.6 7.0 glutamate dehydrogenase/leucine dehydrogenase compare
CCNA_01802 +1.6 3.7 hypothetical protein compare
CCNA_02241 +1.6 5.0 endoribonuclease L-PSP compare
CCNA_00368 +1.6 10.7 phosphonates transport system permease protein phnE compare
CCNA_00189 +1.6 3.5 zinc-finger domain protein compare
CCNA_03514 +1.6 11.5 cytochrome c oxidase assembly protein ctaG compare
CCNA_03072 +1.6 5.5 TetR-family transcriptional regulator compare
CCNA_00778 +1.6 10.9 GTP-binding protein TypA/BipA compare
CCNA_01406 +1.6 7.5 metal-dependent hydrolase compare
CCNA_01603 +1.6 9.9 aspartate aminotransferase compare
CCNA_00562 +1.6 10.1 dihydroorotate dehydrogenase compare
CCNA_00031 +1.6 9.8 toxin protein VapC compare
CCNA_00998 +1.6 8.9 ROS/MUCR transcriptional regulator compare
CCNA_02250 +1.6 4.3 methylcrotonyl-CoA carboxylase biotin-containing subunit compare


Specific Phenotypes

For 6 genes in this experiment

For stress Doxycycline hyclate in Caulobacter crescentus NA1000

For stress Doxycycline hyclate across organisms