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Experiment set3IT062 for
Methanococcus maripaludis JJ
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formate McAA lipolic acid dropout
200 most important genes:
gene
name
fitness
t score
description
MMJJ
_RS00235
-6.2
-23.2
hypothetical protein
compare
MMJJ
_RS07950
-5.0
-4.8
4Fe-4S binding protein
compare
MMJJ
_RS05450
-4.7
-18.0
TIGR03576 family pyridoxal phosphate-dependent enzyme
compare
MMJJ
_RS06855
-4.7
-2.3
DUF2104 domain-containing protein
compare
MMJJ
_RS04485
-4.6
-11.9
riboflavin synthase
compare
MMJJ
_RS06040
-4.6
-6.3
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS03110
-4.6
-5.4
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase
compare
MMJJ
_RS06695
-4.6
-4.8
amidohydrolase
compare
MMJJ
_RS03815
-4.5
-3.6
nascent polypeptide-associated complex protein
compare
MMJJ
_RS05490
-4.4
-3.0
imidazole glycerol phosphate synthase subunit HisF
compare
MMJJ
_RS03820
-4.4
-5.2
hydrogenase formation protein HypD
compare
MMJJ
_RS01935
-4.4
-5.8
O-phosphoseryl-tRNA(Sec) selenium transferase
compare
MMJJ
_RS00270
-4.3
-5.1
adenosylcobinamide-GDP ribazoletransferase
compare
MMJJ
_RS06490
-4.3
-4.2
methanogenesis marker 2 protein
compare
MMJJ
_RS00275
-4.2
-3.7
coenzyme F420-0:L-glutamate ligase
compare
MMJJ
_RS06860
-4.2
-6.1
hypothetical protein
compare
MMJJ
_RS06840
-4.1
-4.8
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS08625
-4.1
-7.8
magnesium/cobalt transporter CorA
compare
MMJJ
_RS03865
-4.1
-1.9
phosphoribosyl-AMP cyclohydrolase
compare
MMJJ
_RS08250
-4.0
-9.1
hydrogenase maturation peptidase HycI
compare
MMJJ
_RS00475
-4.0
-3.9
bifunctional ornithine acetyltransferase/N-acetylglutamate synthase
compare
MMJJ
_RS03840
-3.9
-5.3
DHH family phosphoesterase
compare
MMJJ
_RS02090
-3.9
-8.5
tyramine--L-glutamate ligase
compare
MMJJ
_RS07665
-3.8
-23.5
formate dehydrogenase subunit alpha
compare
MMJJ
_RS08320
-3.8
-3.4
CDP-diacylglycerol--serine O-phosphatidyltransferase
compare
MMJJ
_RS04995
-3.8
-8.7
Tfx family DNA-binding protein
compare
MMJJ
_RS03005
-3.8
-5.4
Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit
compare
MMJJ
_RS07350
-3.8
-4.4
4Fe-4S binding protein
compare
MMJJ
_RS08080
-3.7
-12.1
TIGR00300 family protein
compare
MMJJ
_RS03620
-3.7
-7.7
DUF2097 domain-containing protein
compare
MMJJ
_RS00450
-3.7
-2.9
DUF126 domain-containing protein
compare
MMJJ
_RS03670
-3.7
-7.3
precorrin-2 C(20)-methyltransferase
compare
MMJJ
_RS07670
-3.6
-18.7
Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain
compare
MMJJ
_RS08020
-3.6
-10.2
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS05535
-3.6
-13.9
hypothetical protein
compare
MMJJ
_RS00125
-3.6
-3.4
KEOPS complex subunit Cgi121
compare
MMJJ
_RS05445
-3.6
-3.1
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
MMJJ
_RS04200
-3.6
-7.5
triphosphoribosyl-dephospho-CoA synthase
compare
MMJJ
_RS06510
-3.5
-4.5
LL-diaminopimelate aminotransferase
compare
MMJJ
_RS03615
-3.5
-4.6
cobalt-precorrin-8 methylmutase
compare
MMJJ
_RS05995
-3.5
-3.8
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS06255
-3.5
-9.1
tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3
compare
MMJJ
_RS09375
-3.5
-3.0
hypothetical protein
compare
MMJJ
_RS01865
-3.4
-9.1
peptidyl-tRNA hydrolase Pth2
compare
MMJJ
_RS05650
-3.4
-5.0
formylmethanofuran dehydrogenase subunit B
compare
MMJJ
_RS01360
-3.4
-3.3
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMJJ
_RS03760
-3.4
-5.6
hydrogenase maturation nickel metallochaperone HypA
compare
MMJJ
_RS04730
-3.4
-4.1
tyrosine decarboxylase MfnA
compare
MMJJ
_RS05930
-3.4
-3.6
cell division protein SepF
compare
MMJJ
_RS07705
-3.4
-5.5
GTP-binding protein EngB
compare
MMJJ
_RS07410
-3.4
-6.4
methanogenesis marker protein Mmp4/MtxX
compare
MMJJ
_RS07380
-3.3
-12.2
sulfide-dependent adenosine diphosphate thiazole synthase
compare
MMJJ
_RS04520
-3.3
-5.8
coenzyme F430 synthase
compare
MMJJ
_RS06725
-3.3
-14.9
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMJJ
_RS08055
-3.3
-7.2
methanogenesis marker 14 protein
compare
MMJJ
_RS05620
-3.3
-6.8
CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein
compare
MMJJ
_RS04800
-3.3
-9.4
2-phospho-L-lactate guanylyltransferase
compare
MMJJ
_RS06175
-3.2
-4.3
DUF1743 domain-containing protein
compare
MMJJ
_RS06750
-3.2
-3.6
homoaconitase large subunit
compare
MMJJ
_RS06910
-3.2
-4.0
energy-converting NiFe hydrogenase A subunit EhaA
compare
MMJJ
_RS06110
-3.2
-3.6
bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC
compare
MMJJ
_RS06625
-3.2
-2.4
pyruvate synthase subunit PorB
compare
MMJJ
_RS07655
-3.2
-14.3
hypothetical protein
compare
MMJJ
_RS08005
-3.2
-18.3
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMJJ
_RS04675
-3.2
-9.5
thiamine pyrophosphate-binding protein
compare
MMJJ
_RS05575
-3.2
-6.5
2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase
compare
MMJJ
_RS06915
-3.1
-15.4
helix-turn-helix domain-containing protein
compare
MMJJ
_RS05950
-3.1
-5.8
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
compare
MMJJ
_RS05260
-3.1
-6.8
ATP-grasp domain-containing protein
compare
MMJJ
_RS03785
-3.1
-4.4
hypothetical protein
compare
MMJJ
_RS08000
-3.1
-12.6
HesA/MoeB/ThiF family protein
compare
MMJJ
_RS04685
-3.1
-10.5
carbamoyltransferase HypF
compare
MMJJ
_RS03055
-3.1
-3.6
hypothetical protein
compare
MMJJ
_RS03580
-3.0
-5.0
TIGR00303 family protein
compare
MMJJ
_RS01690
-3.0
-5.0
methanogenesis marker 12 protein
compare
MMJJ
_RS07360
-3.0
-2.5
TIGR00269 family protein
compare
MMJJ
_RS03190
-3.0
-4.0
phosphopyruvate hydratase
compare
MMJJ
_RS05380
-2.9
-2.1
hypothetical protein
compare
MMJJ
_RS03295
-2.9
-19.7
PHP domain-containing protein
compare
MMJJ
_RS07660
-2.9
-9.1
carbonic anhydrase
compare
MMJJ
_RS08535
-2.9
-4.6
NOL1/NOP2/sun family putative RNA methylase
compare
MMJJ
_RS06865
-2.9
-4.0
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS04475
-2.9
-5.3
3,4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMJJ
_RS03200
-2.9
-3.0
uroporphyrinogen-III synthase
compare
MMJJ
_RS03895
-2.9
-6.0
hydrogenase expression/formation protein HypE
compare
MMJJ
_RS08095
-2.8
-6.4
cobyric acid synthase CobQ
compare
MMJJ
_RS06240
-2.8
-3.8
dihydropteroate synthase-like protein
compare
MMJJ
_RS05810
-2.8
-8.0
precorrin-4 C(11)-methyltransferase
compare
MMJJ
_RS07345
-2.8
-7.9
homocysteine biosynthesis protein
compare
MMJJ
_RS01810
-2.8
-3.2
methyl coenzyme M reductase system, component A2
compare
MMJJ
_RS04050
-2.8
-2.9
dihydroneopterin aldolase family protein
compare
MMJJ
_RS05610
-2.8
-5.7
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMJJ
_RS04975
-2.7
-3.1
glycosyltransferase family 4 protein
compare
MMJJ
_RS07720
-2.7
-2.3
UPF0058 family protein
compare
MMJJ
_RS01600
-2.7
-4.2
radical SAM protein
compare
MMJJ
_RS04670
-2.7
-5.6
DUF2117 domain-containing protein
compare
MMJJ
_RS07430
-2.7
-3.6
ribonuclease VapC
compare
MMJJ
_RS06880
-2.7
-2.2
EhaG family protein
compare
MMJJ
_RS01755
-2.7
-3.2
ferrous iron transport protein B
compare
MMJJ
_RS01750
-2.7
-3.6
ferrous iron transport protein A
compare
MMJJ
_RS07785
-2.7
-3.2
fumarate reductase subunit A
compare
MMJJ
_RS03150
-2.6
-8.6
2-phospho-L-lactate transferase
compare
MMJJ
_RS06180
-2.6
-4.2
tryptophan--tRNA ligase
compare
MMJJ
_RS00070
-2.6
-4.6
CooT family nickel-binding protein
compare
MMJJ
_RS00560
-2.6
-5.7
homoisocitrate dehydrogenase
compare
MMJJ
_RS04155
-2.6
-8.4
hypothetical protein
compare
MMJJ
_RS05590
-2.6
-3.3
homoserine dehydrogenase
compare
MMJJ
_RS00050
-2.6
-10.5
AAA family ATPase
compare
MMJJ
_RS06375
-2.6
-5.8
UbiX family flavin prenyltransferase
compare
MMJJ
_RS03095
-2.6
-3.2
bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase
compare
MMJJ
_RS05330
-2.6
-3.8
DNA polymerase II large subunit
compare
MMJJ
_RS05070
-2.6
-2.9
DNA primase catalytic subunit PriS
compare
MMJJ
_RS06785
-2.6
-7.2
RNA ligase partner protein
compare
MMJJ
_RS03270
-2.6
-3.1
ribosome biogenesis/translation initiation ATPase RLI
compare
MMJJ
_RS08660
-2.5
-4.3
acetylornithine transaminase
compare
MMJJ
_RS05065
-2.5
-5.2
(4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase
compare
MMJJ
_RS03800
-2.5
-12.4
aldolase
compare
MMJJ
_RS07275
-2.5
-3.6
formate--phosphoribosylaminoimidazolecarboxamide ligase
compare
MMJJ
_RS06155
-2.5
-7.8
phosphatidylglycerophosphatase A
compare
MMJJ
_RS00040
-2.5
-10.5
CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
compare
MMJJ
_RS01415
-2.5
-3.5
beta-CASP ribonuclease aCPSF1
compare
MMJJ
_RS08330
-2.5
-3.2
SufD family Fe-S cluster assembly protein
compare
MMJJ
_RS02045
-2.5
-2.3
molybdenum cofactor guanylyltransferase
compare
MMJJ
_RS06485
-2.4
-3.7
phosphoglycerate kinase
compare
MMJJ
_RS02275
-2.4
-4.9
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS00520
-2.4
-7.1
PDGLE domain-containing protein
compare
MMJJ
_RS01565
-2.4
-6.7
TIGR00267 family protein
compare
MMJJ
_RS06390
-2.4
-3.5
NADPH-dependent F420 reductase
compare
MMJJ
_RS00215
-2.4
-3.5
CCA tRNA nucleotidyltransferase
compare
MMJJ
_RS02920
-2.3
-2.7
30S ribosomal protein S27ae
compare
MMJJ
_RS03875
-2.3
-4.7
CBS domain-containing protein
compare
MMJJ
_RS06805
-2.3
-4.6
monovalent cation/H+ antiporter subunit E
compare
MMJJ
_RS06835
-2.3
-12.5
4Fe-4S binding protein
compare
MMJJ
_RS00210
-2.3
-2.9
DUF530 family protein
compare
MMJJ
_RS08850
-2.3
-2.9
succinate dehydrogenase/fumarate reductase iron-sulfur subunit
compare
MMJJ
_RS07640
-2.3
-18.3
cache domain-containing protein
compare
MMJJ
_RS03065
-2.3
-12.1
CBS domain-containing protein
compare
MMJJ
_RS03830
-2.3
-9.0
CBS domain-containing protein
compare
MMJJ
_RS09190
-2.3
-2.7
tryptophan synthase subunit beta
compare
MMJJ
_RS05225
-2.3
-2.1
Gar1/Naf1 family protein
compare
MMJJ
_RS08840
-2.3
-4.9
calcium/sodium antiporter
compare
MMJJ
_RS00065
-2.3
-12.3
4Fe-4S dicluster domain-containing protein
compare
MMJJ
_RS03125
-2.3
-4.1
GMC oxidoreductase
compare
MMJJ
_RS04010
-2.3
-8.2
archaeal proteasome endopeptidase complex subunit alpha
compare
MMJJ
_RS00075
-2.2
-11.5
AAA family ATPase
compare
MMJJ
_RS03630
-2.2
-12.5
AMP phosphorylase
compare
MMJJ
_RS08855
-2.2
-3.7
cyclic pyranopterin monophosphate synthase MoaC
compare
MMJJ
_RS06250
-2.2
-2.6
nicotinamide-nucleotide adenylyltransferase
compare
MMJJ
_RS00045
-2.2
-13.9
CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
compare
MMJJ
_RS05190
-2.2
-8.7
gamma carbonic anhydrase family protein
compare
MMJJ
_RS05655
-2.2
-5.6
HisA/HisF family protein
compare
MMJJ
_RS07635
-2.2
-12.1
response regulator transcription factor
compare
MMJJ
_RS02040
-2.2
-2.0
Asp-tRNA(Asn) amidotransferase subunit GatC
compare
MMJJ
_RS00530
-2.2
-11.2
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS00355
-2.2
-3.7
ribonuclease P protein component 4
compare
MMJJ
_RS07650
-2.2
-15.0
formate/nitrite transporter family protein
compare
MMJJ
_RS00035
-2.2
-15.1
CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
compare
MMJJ
_RS05295
-2.2
-9.7
cobyrinic acid a,c-diamide synthase
compare
MMJJ
_RS09175
-2.2
-1.6
anthranilate synthase component I
compare
MMJJ
_RS00060
-2.1
-14.1
acetyl-CoA decarbonylase/synthase complex subunit gamma
compare
MMJJ
_RS06220
-2.1
-4.3
polyamine aminopropyltransferase
compare
MMJJ
_RS07155
-2.1
-7.5
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMJJ
_RS08340
-2.1
-4.4
archaeoflavoprotein AfpA
compare
MMJJ
_RS02055
-2.1
-12.8
GTP 3',8-cyclase MoaA
compare
MMJJ
_RS06225
-2.1
-3.1
adenosylmethionine decarboxylase
compare
MMJJ
_RS07370
-2.1
-4.1
tRNA 4-thiouridine(8) synthase ThiI
compare
MMJJ
_RS06700
-2.1
-6.0
L-seryl-tRNA(Sec) kinase
compare
MMJJ
_RS05155
-2.1
-6.9
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH
compare
MMJJ
_RS06905
-2.1
-2.3
hypothetical protein
compare
MMJJ
_RS06730
-2.0
-6.4
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS08065
-2.0
-3.7
precorrin-6Y C5,15-methyltransferase (decarboxylating) subunit CbiT
compare
MMJJ
_RS00055
-2.0
-8.5
CO dehydrogenase/acetyl-CoA synthase subunit delta
compare
MMJJ
_RS05540
-2.0
-14.5
LysR family transcriptional regulator
compare
MMJJ
_RS05375
-2.0
-13.8
radical SAM protein
compare
MMJJ
_RS00580
-2.0
-2.6
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG
compare
MMJJ
_RS00515
-2.0
-10.9
cobalt transporter CbiM
compare
MMJJ
_RS07995
-2.0
-6.1
molybdenum cofactor biosynthesis protein MoaE
compare
MMJJ
_RS04595
-2.0
-4.0
hypothetical protein
compare
MMJJ
_RS03660
-2.0
-4.2
DUF447 family protein
compare
MMJJ
_RS04650
-1.9
-5.5
nitrogenase iron protein
compare
MMJJ
_RS06185
-1.9
-4.3
cobalamin biosynthesis protein
compare
MMJJ
_RS00370
-1.9
-2.4
asparagine synthase (glutamine-hydrolyzing)
compare
MMJJ
_RS06010
-1.9
-7.0
hypothetical protein
compare
MMJJ
_RS03060
-1.9
-2.5
methanogenesis marker 7 protein
compare
MMJJ
_RS01355
-1.9
-2.9
UDP-N-acetyl-D-mannosamine dehydrogenase
compare
MMJJ
_RS07000
-1.9
-1.9
TrkH family potassium uptake protein
compare
MMJJ
_RS04790
-1.9
-3.5
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMJJ
_RS00600
-1.9
-2.5
hydroxymethylbilane synthase
compare
MMJJ
_RS05360
-1.9
-7.4
nickel-responsive transcriptional regulator NikR
compare
MMJJ
_RS01345
-1.9
-4.0
(5-formylfuran-3-yl)methyl phosphate synthase
compare
MMJJ
_RS08480
-1.9
-6.2
hydroxyethylthiazole kinase
compare
MMJJ
_RS08585
-1.9
-9.6
M42 family metallopeptidase
compare
MMJJ
_RS02200
-1.8
-8.1
chorismate pyruvate-lyase family protein
compare
MMJJ
_RS00265
-1.8
-6.4
TIGR02253 family HAD-type hydrolase
compare
MMJJ
_RS03115
-1.8
-5.6
sulfopyruvate decarboxylase subunit alpha
compare
MMJJ
_RS01410
-1.8
-4.6
archaeal proteasome endopeptidase complex subunit beta
compare
MMJJ
_RS03500
-1.8
-10.7
F420-dependent methylenetetrahydromethanopterin dehydrogenase
compare
MMJJ
_RS06050
-1.8
-8.5
molybdopterin molybdotransferase MoeA
compare
MMJJ
_RS07980
-1.8
-9.6
biotin synthase BioB
compare
MMJJ
_RS06270
-1.8
-9.2
dethiobiotin synthase
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments