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Experiment set3IT061 for
Methanococcus maripaludis JJ
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formate McAA lipolic acid dropout
200 most important genes:
gene
name
fitness
t score
description
MMJJ
_RS00580
-6.1
-3.2
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG
compare
MMJJ
_RS04475
-5.9
-4.1
3,4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMJJ
_RS00235
-5.8
-19.0
hypothetical protein
compare
MMJJ
_RS00275
-5.4
-3.7
coenzyme F420-0:L-glutamate ligase
compare
MMJJ
_RS04485
-5.1
-12.6
riboflavin synthase
compare
MMJJ
_RS04200
-5.0
-9.0
triphosphoribosyl-dephospho-CoA synthase
compare
MMJJ
_RS00210
-5.0
-3.4
DUF530 family protein
compare
MMJJ
_RS07720
-5.0
-3.0
UPF0058 family protein
compare
MMJJ
_RS01600
-4.9
-3.4
radical SAM protein
compare
MMJJ
_RS00450
-4.6
-2.9
DUF126 domain-containing protein
compare
MMJJ
_RS06855
-4.5
-2.3
DUF2104 domain-containing protein
compare
MMJJ
_RS00600
-4.5
-5.1
hydroxymethylbilane synthase
compare
MMJJ
_RS05450
-4.5
-18.8
TIGR03576 family pyridoxal phosphate-dependent enzyme
compare
MMJJ
_RS06910
-4.4
-4.2
energy-converting NiFe hydrogenase A subunit EhaA
compare
MMJJ
_RS06695
-4.3
-4.9
amidohydrolase
compare
MMJJ
_RS05445
-4.3
-3.2
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
MMJJ
_RS02045
-4.2
-4.8
molybdenum cofactor guanylyltransferase
compare
MMJJ
_RS05070
-4.2
-3.8
DNA primase catalytic subunit PriS
compare
MMJJ
_RS09175
-4.1
-1.8
anthranilate synthase component I
compare
MMJJ
_RS02040
-4.1
-3.4
Asp-tRNA(Asn) amidotransferase subunit GatC
compare
MMJJ
_RS03785
-4.1
-2.8
hypothetical protein
compare
MMJJ
_RS06390
-4.1
-3.0
NADPH-dependent F420 reductase
compare
MMJJ
_RS07950
-4.1
-4.7
4Fe-4S binding protein
compare
MMJJ
_RS06860
-4.0
-4.3
hypothetical protein
compare
MMJJ
_RS08320
-4.0
-4.4
CDP-diacylglycerol--serine O-phosphatidyltransferase
compare
MMJJ
_RS03270
-3.9
-3.4
ribosome biogenesis/translation initiation ATPase RLI
compare
MMJJ
_RS07360
-3.9
-2.7
TIGR00269 family protein
compare
MMJJ
_RS00270
-3.9
-5.3
adenosylcobinamide-GDP ribazoletransferase
compare
MMJJ
_RS05950
-3.9
-4.6
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
compare
MMJJ
_RS01750
-3.9
-4.2
ferrous iron transport protein A
compare
MMJJ
_RS08625
-3.9
-8.2
magnesium/cobalt transporter CorA
compare
MMJJ
_RS03055
-3.8
-4.3
hypothetical protein
compare
MMJJ
_RS06625
-3.8
-3.1
pyruvate synthase subunit PorB
compare
MMJJ
_RS03820
-3.8
-5.7
hydrogenase formation protein HypD
compare
MMJJ
_RS08250
-3.8
-8.4
hydrogenase maturation peptidase HycI
compare
MMJJ
_RS01870
-3.7
-3.5
methanogenesis marker 15 protein
compare
MMJJ
_RS06255
-3.7
-8.8
tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3
compare
MMJJ
_RS01935
-3.7
-6.1
O-phosphoseryl-tRNA(Sec) selenium transferase
compare
MMJJ
_RS07670
-3.7
-18.2
Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain
compare
MMJJ
_RS07665
-3.7
-22.8
formate dehydrogenase subunit alpha
compare
MMJJ
_RS08020
-3.7
-10.2
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS06240
-3.6
-3.9
dihydropteroate synthase-like protein
compare
MMJJ
_RS00570
-3.6
-3.1
ribonuclease P
compare
MMJJ
_RS07705
-3.6
-4.9
GTP-binding protein EngB
compare
MMJJ
_RS04790
-3.6
-6.4
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMJJ
_RS03670
-3.6
-7.0
precorrin-2 C(20)-methyltransferase
compare
MMJJ
_RS05330
-3.6
-3.5
DNA polymerase II large subunit
compare
MMJJ
_RS05575
-3.6
-6.7
2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase
compare
MMJJ
_RS00520
-3.6
-7.4
PDGLE domain-containing protein
compare
MMJJ
_RS03615
-3.6
-4.1
cobalt-precorrin-8 methylmutase
compare
MMJJ
_RS05535
-3.5
-15.8
hypothetical protein
compare
MMJJ
_RS09190
-3.5
-2.2
tryptophan synthase subunit beta
compare
MMJJ
_RS01200
-3.5
-3.4
PRC-barrel domain-containing protein
compare
MMJJ
_RS06725
-3.5
-13.9
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMJJ
_RS06875
-3.5
-4.2
hypothetical protein
compare
MMJJ
_RS07380
-3.5
-10.4
sulfide-dependent adenosine diphosphate thiazole synthase
compare
MMJJ
_RS06225
-3.5
-3.2
adenosylmethionine decarboxylase
compare
MMJJ
_RS03190
-3.5
-3.3
phosphopyruvate hydratase
compare
MMJJ
_RS04685
-3.5
-11.2
carbamoyltransferase HypF
compare
MMJJ
_RS03840
-3.5
-6.1
DHH family phosphoesterase
compare
MMJJ
_RS03580
-3.4
-5.2
TIGR00303 family protein
compare
MMJJ
_RS05260
-3.4
-8.2
ATP-grasp domain-containing protein
compare
MMJJ
_RS07655
-3.4
-15.5
hypothetical protein
compare
MMJJ
_RS06175
-3.4
-3.4
DUF1743 domain-containing protein
compare
MMJJ
_RS04970
-3.4
-3.1
DUF655 domain-containing protein
compare
MMJJ
_RS08080
-3.3
-10.1
TIGR00300 family protein
compare
MMJJ
_RS07275
-3.3
-3.9
formate--phosphoribosylaminoimidazolecarboxamide ligase
compare
MMJJ
_RS06490
-3.3
-4.7
methanogenesis marker 2 protein
compare
MMJJ
_RS03110
-3.3
-5.8
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase
compare
MMJJ
_RS07000
-3.3
-2.4
TrkH family potassium uptake protein
compare
MMJJ
_RS08850
-3.3
-3.6
succinate dehydrogenase/fumarate reductase iron-sulfur subunit
compare
MMJJ
_RS06040
-3.2
-6.2
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS08000
-3.1
-9.5
HesA/MoeB/ThiF family protein
compare
MMJJ
_RS06805
-3.1
-3.6
monovalent cation/H+ antiporter subunit E
compare
MMJJ
_RS06915
-3.1
-14.0
helix-turn-helix domain-containing protein
compare
MMJJ
_RS03125
-3.1
-4.9
GMC oxidoreductase
compare
MMJJ
_RS06930
-3.1
-4.0
type II methionyl aminopeptidase
compare
MMJJ
_RS02090
-3.1
-7.3
tyramine--L-glutamate ligase
compare
MMJJ
_RS05490
-3.1
-4.1
imidazole glycerol phosphate synthase subunit HisF
compare
MMJJ
_RS01755
-3.1
-3.6
ferrous iron transport protein B
compare
MMJJ
_RS05810
-3.0
-9.5
precorrin-4 C(11)-methyltransferase
compare
MMJJ
_RS08055
-3.0
-7.9
methanogenesis marker 14 protein
compare
MMJJ
_RS05610
-3.0
-6.4
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMJJ
_RS03660
-2.9
-5.5
DUF447 family protein
compare
MMJJ
_RS04975
-2.9
-2.8
glycosyltransferase family 4 protein
compare
MMJJ
_RS05650
-2.9
-3.7
formylmethanofuran dehydrogenase subunit B
compare
MMJJ
_RS07785
-2.9
-4.4
fumarate reductase subunit A
compare
MMJJ
_RS05620
-2.9
-6.4
CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein
compare
MMJJ
_RS04730
-2.8
-3.6
tyrosine decarboxylase MfnA
compare
MMJJ
_RS04995
-2.8
-8.3
Tfx family DNA-binding protein
compare
MMJJ
_RS04155
-2.8
-9.4
hypothetical protein
compare
MMJJ
_RS05935
-2.8
-3.7
Era-like GTP-binding protein
compare
MMJJ
_RS04800
-2.8
-6.3
2-phospho-L-lactate guanylyltransferase
compare
MMJJ
_RS06750
-2.8
-4.0
homoaconitase large subunit
compare
MMJJ
_RS03065
-2.8
-11.9
CBS domain-containing protein
compare
MMJJ
_RS00050
-2.8
-10.7
AAA family ATPase
compare
MMJJ
_RS03295
-2.8
-15.1
PHP domain-containing protein
compare
MMJJ
_RS08005
-2.8
-15.7
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMJJ
_RS03060
-2.7
-4.0
methanogenesis marker 7 protein
compare
MMJJ
_RS03150
-2.7
-8.8
2-phospho-L-lactate transferase
compare
MMJJ
_RS04675
-2.7
-6.6
thiamine pyrophosphate-binding protein
compare
MMJJ
_RS03875
-2.7
-5.6
CBS domain-containing protein
compare
MMJJ
_RS09375
-2.7
-2.7
hypothetical protein
compare
MMJJ
_RS03200
-2.7
-3.6
uroporphyrinogen-III synthase
compare
MMJJ
_RS07245
-2.7
-6.3
amidohydrolase family protein
compare
MMJJ
_RS07350
-2.6
-3.5
4Fe-4S binding protein
compare
MMJJ
_RS07430
-2.6
-5.1
ribonuclease VapC
compare
MMJJ
_RS04985
-2.6
-5.2
glutamyl-tRNA reductase
compare
MMJJ
_RS00125
-2.6
-2.8
KEOPS complex subunit Cgi121
compare
MMJJ
_RS00530
-2.6
-12.3
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS04615
-2.6
-4.7
methanogenesis marker 3 protein
compare
MMJJ
_RS00560
-2.6
-4.3
homoisocitrate dehydrogenase
compare
MMJJ
_RS04875
-2.6
-2.3
tRNA-Lys
compare
MMJJ
_RS08840
-2.6
-5.3
calcium/sodium antiporter
compare
MMJJ
_RS03815
-2.6
-2.7
nascent polypeptide-associated complex protein
compare
MMJJ
_RS03800
-2.5
-11.5
aldolase
compare
MMJJ
_RS06030
-2.5
-7.6
4Fe-4S binding protein
compare
MMJJ
_RS07660
-2.5
-11.1
carbonic anhydrase
compare
MMJJ
_RS06785
-2.5
-7.7
RNA ligase partner protein
compare
MMJJ
_RS01360
-2.5
-3.6
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMJJ
_RS08855
-2.5
-5.0
cyclic pyranopterin monophosphate synthase MoaC
compare
MMJJ
_RS05225
-2.5
-2.4
Gar1/Naf1 family protein
compare
MMJJ
_RS06375
-2.5
-5.4
UbiX family flavin prenyltransferase
compare
MMJJ
_RS06180
-2.5
-3.3
tryptophan--tRNA ligase
compare
MMJJ
_RS01415
-2.5
-3.0
beta-CASP ribonuclease aCPSF1
compare
MMJJ
_RS00475
-2.5
-3.5
bifunctional ornithine acetyltransferase/N-acetylglutamate synthase
compare
MMJJ
_RS03620
-2.5
-6.1
DUF2097 domain-containing protein
compare
MMJJ
_RS02935
-2.5
-4.2
DNA-directed RNA polymerase subunit E''
compare
MMJJ
_RS08095
-2.5
-4.9
cobyric acid synthase CobQ
compare
MMJJ
_RS04520
-2.5
-5.2
coenzyme F430 synthase
compare
MMJJ
_RS05065
-2.5
-5.2
(4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase
compare
MMJJ
_RS05720
-2.5
-3.4
glutamine--fructose-6-phosphate transaminase (isomerizing)
compare
MMJJ
_RS00045
-2.4
-14.5
CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
compare
MMJJ
_RS08340
-2.4
-5.3
archaeoflavoprotein AfpA
compare
MMJJ
_RS00070
-2.4
-6.5
CooT family nickel-binding protein
compare
MMJJ
_RS07155
-2.4
-9.8
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMJJ
_RS03115
-2.4
-7.4
sulfopyruvate decarboxylase subunit alpha
compare
MMJJ
_RS06220
-2.4
-6.1
polyamine aminopropyltransferase
compare
MMJJ
_RS00040
-2.4
-7.0
CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
compare
MMJJ
_RS01565
-2.4
-8.5
TIGR00267 family protein
compare
MMJJ
_RS00055
-2.4
-10.3
CO dehydrogenase/acetyl-CoA synthase subunit delta
compare
MMJJ
_RS06840
-2.4
-4.5
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS01865
-2.4
-6.1
peptidyl-tRNA hydrolase Pth2
compare
MMJJ
_RS08155
-2.4
-4.4
cobalt-precorrin-5B (C(1))-methyltransferase CbiD
compare
MMJJ
_RS03830
-2.4
-10.7
CBS domain-containing protein
compare
MMJJ
_RS06185
-2.4
-5.7
cobalamin biosynthesis protein
compare
MMJJ
_RS00060
-2.3
-16.0
acetyl-CoA decarbonylase/synthase complex subunit gamma
compare
MMJJ
_RS02920
-2.3
-2.2
30S ribosomal protein S27ae
compare
MMJJ
_RS00075
-2.3
-11.4
AAA family ATPase
compare
MMJJ
_RS00035
-2.3
-15.1
CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
compare
MMJJ
_RS04655
-2.3
-7.2
FAD-dependent oxidoreductase
compare
MMJJ
_RS00370
-2.3
-2.5
asparagine synthase (glutamine-hydrolyzing)
compare
MMJJ
_RS05360
-2.3
-6.2
nickel-responsive transcriptional regulator NikR
compare
MMJJ
_RS06835
-2.3
-10.8
4Fe-4S binding protein
compare
MMJJ
_RS03005
-2.3
-5.2
Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit
compare
MMJJ
_RS05655
-2.3
-6.5
HisA/HisF family protein
compare
MMJJ
_RS05295
-2.3
-9.6
cobyrinic acid a,c-diamide synthase
compare
MMJJ
_RS06250
-2.3
-3.6
nicotinamide-nucleotide adenylyltransferase
compare
MMJJ
_RS01690
-2.3
-4.0
methanogenesis marker 12 protein
compare
MMJJ
_RS00065
-2.2
-9.7
4Fe-4S dicluster domain-containing protein
compare
MMJJ
_RS04595
-2.2
-4.0
hypothetical protein
compare
MMJJ
_RS05190
-2.2
-9.5
gamma carbonic anhydrase family protein
compare
MMJJ
_RS00080
-2.2
-13.1
DUF166 domain-containing protein
compare
MMJJ
_RS03630
-2.2
-12.4
AMP phosphorylase
compare
MMJJ
_RS07410
-2.2
-3.7
methanogenesis marker protein Mmp4/MtxX
compare
MMJJ
_RS07945
-2.2
-2.6
4Fe-4S binding protein
compare
MMJJ
_RS00215
-2.2
-3.7
CCA tRNA nucleotidyltransferase
compare
MMJJ
_RS05375
-2.2
-13.1
radical SAM protein
compare
MMJJ
_RS01355
-2.1
-4.4
UDP-N-acetyl-D-mannosamine dehydrogenase
compare
MMJJ
_RS08330
-2.1
-2.8
SufD family Fe-S cluster assembly protein
compare
MMJJ
_RS07190
-2.1
-4.8
RtcB family protein
compare
MMJJ
_RS06865
-2.1
-2.8
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS08620
-2.1
-3.5
DUF373 family protein
compare
MMJJ
_RS02275
-2.1
-3.4
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS08190
-2.1
-2.8
hypothetical protein
compare
MMJJ
_RS07345
-2.1
-6.9
homocysteine biosynthesis protein
compare
MMJJ
_RS06155
-2.1
-5.9
phosphatidylglycerophosphatase A
compare
MMJJ
_RS04110
-2.0
-4.4
hypothetical protein
compare
MMJJ
_RS03895
-2.0
-3.1
hydrogenase expression/formation protein HypE
compare
MMJJ
_RS00205
-2.0
-5.9
adenosylcobinamide-phosphate synthase CbiB
compare
MMJJ
_RS05155
-2.0
-6.2
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH
compare
MMJJ
_RS00645
-2.0
-11.1
adenosylmethionine--8-amino-7-oxononanoate transaminase
compare
MMJJ
_RS07640
-2.0
-16.3
cache domain-containing protein
compare
MMJJ
_RS07980
-2.0
-10.9
biotin synthase BioB
compare
MMJJ
_RS05995
-2.0
-2.3
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS04565
-2.0
-2.3
sirohydrochlorin nickelochelatase
compare
MMJJ
_RS03865
-2.0
-2.4
phosphoribosyl-AMP cyclohydrolase
compare
MMJJ
_RS01345
-2.0
-4.2
(5-formylfuran-3-yl)methyl phosphate synthase
compare
MMJJ
_RS02055
-2.0
-9.8
GTP 3',8-cyclase MoaA
compare
MMJJ
_RS08535
-2.0
-3.9
NOL1/NOP2/sun family putative RNA methylase
compare
MMJJ
_RS07995
-2.0
-7.0
molybdenum cofactor biosynthesis protein MoaE
compare
MMJJ
_RS00515
-2.0
-9.6
cobalt transporter CbiM
compare
MMJJ
_RS04980
-1.9
-3.3
bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase
compare
MMJJ
_RS00265
-1.9
-7.0
TIGR02253 family HAD-type hydrolase
compare
MMJJ
_RS06270
-1.9
-8.5
dethiobiotin synthase
compare
MMJJ
_RS01880
-1.9
-2.5
RlmE family RNA methyltransferase
compare
MMJJ
_RS06485
-1.9
-3.2
phosphoglycerate kinase
compare
MMJJ
_RS04010
-1.9
-7.7
archaeal proteasome endopeptidase complex subunit alpha
compare
MMJJ
_RS06730
-1.9
-6.7
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS03095
-1.9
-2.9
bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments