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Experiment set3IT060 for
Methanococcus maripaludis JJ
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formate McAA p-aminobenzoic acid dropout
200 most important genes:
gene
name
fitness
t score
description
MMJJ
_RS00235
-6.6
-20.8
hypothetical protein
compare
MMJJ
_RS09375
-5.2
-2.9
hypothetical protein
compare
MMJJ
_RS06625
-5.2
-3.4
pyruvate synthase subunit PorB
compare
MMJJ
_RS04200
-5.1
-7.8
triphosphoribosyl-dephospho-CoA synthase
compare
MMJJ
_RS05445
-5.0
-3.2
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
MMJJ
_RS03760
-4.6
-4.5
hydrogenase maturation nickel metallochaperone HypA
compare
MMJJ
_RS06040
-4.6
-5.4
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS05450
-4.5
-15.6
TIGR03576 family pyridoxal phosphate-dependent enzyme
compare
MMJJ
_RS01810
-4.5
-3.1
methyl coenzyme M reductase system, component A2
compare
MMJJ
_RS06695
-4.5
-4.3
amidohydrolase
compare
MMJJ
_RS06875
-4.5
-4.0
hypothetical protein
compare
MMJJ
_RS01935
-4.4
-5.9
O-phosphoseryl-tRNA(Sec) selenium transferase
compare
MMJJ
_RS06910
-4.2
-4.0
energy-converting NiFe hydrogenase A subunit EhaA
compare
MMJJ
_RS08625
-4.2
-6.9
magnesium/cobalt transporter CorA
compare
MMJJ
_RS03580
-4.1
-4.8
TIGR00303 family protein
compare
MMJJ
_RS01600
-4.1
-3.9
radical SAM protein
compare
MMJJ
_RS06240
-4.1
-4.6
dihydropteroate synthase-like protein
compare
MMJJ
_RS05575
-4.1
-5.6
2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase
compare
MMJJ
_RS02045
-4.0
-4.3
molybdenum cofactor guanylyltransferase
compare
MMJJ
_RS07665
-4.0
-24.0
formate dehydrogenase subunit alpha
compare
MMJJ
_RS08320
-4.0
-3.4
CDP-diacylglycerol--serine O-phosphatidyltransferase
compare
MMJJ
_RS03820
-3.9
-5.3
hydrogenase formation protein HypD
compare
MMJJ
_RS05590
-3.9
-3.4
homoserine dehydrogenase
compare
MMJJ
_RS05260
-3.9
-8.2
ATP-grasp domain-containing protein
compare
MMJJ
_RS03895
-3.9
-5.0
hydrogenase expression/formation protein HypE
compare
MMJJ
_RS05650
-3.9
-4.5
formylmethanofuran dehydrogenase subunit B
compare
MMJJ
_RS07670
-3.8
-17.0
Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain
compare
MMJJ
_RS06490
-3.8
-4.5
methanogenesis marker 2 protein
compare
MMJJ
_RS04155
-3.8
-9.7
hypothetical protein
compare
MMJJ
_RS00570
-3.8
-2.6
ribonuclease P
compare
MMJJ
_RS04730
-3.8
-3.6
tyrosine decarboxylase MfnA
compare
MMJJ
_RS02275
-3.8
-6.2
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS07360
-3.7
-2.6
TIGR00269 family protein
compare
MMJJ
_RS05930
-3.7
-3.3
cell division protein SepF
compare
MMJJ
_RS06855
-3.6
-2.9
DUF2104 domain-containing protein
compare
MMJJ
_RS08005
-3.6
-18.0
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMJJ
_RS07655
-3.6
-15.0
hypothetical protein
compare
MMJJ
_RS08660
-3.6
-4.2
acetylornithine transaminase
compare
MMJJ
_RS05535
-3.6
-16.6
hypothetical protein
compare
MMJJ
_RS00450
-3.6
-2.8
DUF126 domain-containing protein
compare
MMJJ
_RS00275
-3.6
-3.8
coenzyme F420-0:L-glutamate ligase
compare
MMJJ
_RS03270
-3.5
-3.3
ribosome biogenesis/translation initiation ATPase RLI
compare
MMJJ
_RS06860
-3.5
-5.6
hypothetical protein
compare
MMJJ
_RS06725
-3.5
-14.3
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMJJ
_RS05620
-3.5
-5.2
CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein
compare
MMJJ
_RS03095
-3.4
-3.3
bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase
compare
MMJJ
_RS05610
-3.4
-5.6
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMJJ
_RS00600
-3.4
-4.4
hydroxymethylbilane synthase
compare
MMJJ
_RS06255
-3.4
-8.1
tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3
compare
MMJJ
_RS01360
-3.3
-3.2
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMJJ
_RS06805
-3.3
-4.3
monovalent cation/H+ antiporter subunit E
compare
MMJJ
_RS06215
-3.3
-6.9
agmatinase
compare
MMJJ
_RS06225
-3.3
-3.1
adenosylmethionine decarboxylase
compare
MMJJ
_RS03840
-3.3
-5.3
DHH family phosphoesterase
compare
MMJJ
_RS03110
-3.2
-5.7
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase
compare
MMJJ
_RS00560
-3.2
-4.5
homoisocitrate dehydrogenase
compare
MMJJ
_RS04790
-3.2
-4.3
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMJJ
_RS06915
-3.2
-13.7
helix-turn-helix domain-containing protein
compare
MMJJ
_RS08020
-3.2
-8.1
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS00215
-3.1
-3.5
CCA tRNA nucleotidyltransferase
compare
MMJJ
_RS03200
-3.1
-3.6
uroporphyrinogen-III synthase
compare
MMJJ
_RS06250
-3.1
-3.6
nicotinamide-nucleotide adenylyltransferase
compare
MMJJ
_RS08000
-3.1
-11.0
HesA/MoeB/ThiF family protein
compare
MMJJ
_RS04995
-3.1
-7.8
Tfx family DNA-binding protein
compare
MMJJ
_RS04050
-3.1
-2.2
dihydroneopterin aldolase family protein
compare
MMJJ
_RS01415
-3.1
-4.3
beta-CASP ribonuclease aCPSF1
compare
MMJJ
_RS06180
-3.0
-4.1
tryptophan--tRNA ligase
compare
MMJJ
_RS01880
-3.0
-3.9
RlmE family RNA methyltransferase
compare
MMJJ
_RS03065
-3.0
-12.9
CBS domain-containing protein
compare
MMJJ
_RS06905
-3.0
-3.3
hypothetical protein
compare
MMJJ
_RS03615
-3.0
-3.8
cobalt-precorrin-8 methylmutase
compare
MMJJ
_RS04675
-3.0
-7.8
thiamine pyrophosphate-binding protein
compare
MMJJ
_RS02090
-3.0
-5.3
tyramine--L-glutamate ligase
compare
MMJJ
_RS08055
-3.0
-8.3
methanogenesis marker 14 protein
compare
MMJJ
_RS04685
-2.9
-11.2
carbamoyltransferase HypF
compare
MMJJ
_RS03150
-2.9
-6.8
2-phospho-L-lactate transferase
compare
MMJJ
_RS08250
-2.9
-8.5
hydrogenase maturation peptidase HycI
compare
MMJJ
_RS05330
-2.9
-3.4
DNA polymerase II large subunit
compare
MMJJ
_RS00210
-2.9
-3.3
DUF530 family protein
compare
MMJJ
_RS05490
-2.9
-3.8
imidazole glycerol phosphate synthase subunit HisF
compare
MMJJ
_RS01475
-2.9
-2.6
signal recognition particle-docking protein FtsY
compare
MMJJ
_RS06220
-2.9
-6.9
polyamine aminopropyltransferase
compare
MMJJ
_RS08080
-2.9
-9.0
TIGR00300 family protein
compare
MMJJ
_RS05070
-2.8
-2.5
DNA primase catalytic subunit PriS
compare
MMJJ
_RS02920
-2.8
-2.7
30S ribosomal protein S27ae
compare
MMJJ
_RS03785
-2.8
-3.6
hypothetical protein
compare
MMJJ
_RS01755
-2.8
-3.4
ferrous iron transport protein B
compare
MMJJ
_RS03620
-2.8
-7.0
DUF2097 domain-containing protein
compare
MMJJ
_RS04520
-2.8
-6.0
coenzyme F430 synthase
compare
MMJJ
_RS03875
-2.8
-6.0
CBS domain-containing protein
compare
MMJJ
_RS08855
-2.8
-5.7
cyclic pyranopterin monophosphate synthase MoaC
compare
MMJJ
_RS06785
-2.8
-8.0
RNA ligase partner protein
compare
MMJJ
_RS03190
-2.7
-3.7
phosphopyruvate hydratase
compare
MMJJ
_RS03005
-2.7
-5.1
Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit
compare
MMJJ
_RS03660
-2.7
-3.9
DUF447 family protein
compare
MMJJ
_RS07995
-2.7
-10.2
molybdenum cofactor biosynthesis protein MoaE
compare
MMJJ
_RS06155
-2.7
-6.9
phosphatidylglycerophosphatase A
compare
MMJJ
_RS03295
-2.7
-14.3
PHP domain-containing protein
compare
MMJJ
_RS05655
-2.7
-7.1
HisA/HisF family protein
compare
MMJJ
_RS03055
-2.6
-3.7
hypothetical protein
compare
MMJJ
_RS07705
-2.6
-4.2
GTP-binding protein EngB
compare
MMJJ
_RS07660
-2.6
-9.4
carbonic anhydrase
compare
MMJJ
_RS06110
-2.6
-3.1
bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC
compare
MMJJ
_RS03830
-2.6
-10.4
CBS domain-containing protein
compare
MMJJ
_RS04650
-2.6
-7.6
nitrogenase iron protein
compare
MMJJ
_RS03670
-2.6
-4.7
precorrin-2 C(20)-methyltransferase
compare
MMJJ
_RS06840
-2.6
-4.6
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS08095
-2.6
-5.6
cobyric acid synthase CobQ
compare
MMJJ
_RS06485
-2.6
-4.2
phosphoglycerate kinase
compare
MMJJ
_RS05995
-2.6
-3.7
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS04485
-2.6
-11.3
riboflavin synthase
compare
MMJJ
_RS03800
-2.6
-10.8
aldolase
compare
MMJJ
_RS07380
-2.6
-8.6
sulfide-dependent adenosine diphosphate thiazole synthase
compare
MMJJ
_RS06390
-2.5
-3.0
NADPH-dependent F420 reductase
compare
MMJJ
_RS04800
-2.5
-6.1
2-phospho-L-lactate guanylyltransferase
compare
MMJJ
_RS04655
-2.5
-5.8
FAD-dependent oxidoreductase
compare
MMJJ
_RS00050
-2.5
-10.1
AAA family ATPase
compare
MMJJ
_RS00355
-2.5
-4.3
ribonuclease P protein component 4
compare
MMJJ
_RS07635
-2.5
-14.0
response regulator transcription factor
compare
MMJJ
_RS07350
-2.5
-4.2
4Fe-4S binding protein
compare
MMJJ
_RS07950
-2.5
-3.1
4Fe-4S binding protein
compare
MMJJ
_RS01870
-2.5
-3.0
methanogenesis marker 15 protein
compare
MMJJ
_RS05190
-2.5
-7.8
gamma carbonic anhydrase family protein
compare
MMJJ
_RS03115
-2.5
-5.0
sulfopyruvate decarboxylase subunit alpha
compare
MMJJ
_RS06705
-2.5
-5.5
bifunctional NADP phosphatase/NAD kinase
compare
MMJJ
_RS07430
-2.5
-5.1
ribonuclease VapC
compare
MMJJ
_RS07155
-2.5
-9.3
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMJJ
_RS05935
-2.5
-3.3
Era-like GTP-binding protein
compare
MMJJ
_RS07640
-2.4
-19.6
cache domain-containing protein
compare
MMJJ
_RS03630
-2.4
-12.1
AMP phosphorylase
compare
MMJJ
_RS00580
-2.4
-2.1
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG
compare
MMJJ
_RS08340
-2.4
-4.4
archaeoflavoprotein AfpA
compare
MMJJ
_RS07355
-2.4
-5.8
MoaD/ThiS family protein
compare
MMJJ
_RS07190
-2.4
-4.6
RtcB family protein
compare
MMJJ
_RS05065
-2.4
-5.6
(4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase
compare
MMJJ
_RS01345
-2.4
-4.6
(5-formylfuran-3-yl)methyl phosphate synthase
compare
MMJJ
_RS00520
-2.4
-6.4
PDGLE domain-containing protein
compare
MMJJ
_RS06510
-2.3
-3.3
LL-diaminopimelate aminotransferase
compare
MMJJ
_RS01565
-2.3
-7.6
TIGR00267 family protein
compare
MMJJ
_RS06375
-2.3
-4.3
UbiX family flavin prenyltransferase
compare
MMJJ
_RS07410
-2.3
-5.0
methanogenesis marker protein Mmp4/MtxX
compare
MMJJ
_RS01405
-2.3
-1.4
proline--tRNA ligase
compare
MMJJ
_RS07245
-2.3
-6.0
amidohydrolase family protein
compare
MMJJ
_RS07725
-2.3
-6.3
DNA primase DnaG
compare
MMJJ
_RS06760
-2.2
-5.6
Ni-sirohydrochlorin a,c-diamide synthase
compare
MMJJ
_RS09190
-2.2
-2.9
tryptophan synthase subunit beta
compare
MMJJ
_RS06835
-2.2
-10.3
4Fe-4S binding protein
compare
MMJJ
_RS03815
-2.2
-3.0
nascent polypeptide-associated complex protein
compare
MMJJ
_RS08330
-2.2
-2.4
SufD family Fe-S cluster assembly protein
compare
MMJJ
_RS02055
-2.2
-11.6
GTP 3',8-cyclase MoaA
compare
MMJJ
_RS07650
-2.2
-14.8
formate/nitrite transporter family protein
compare
MMJJ
_RS05375
-2.2
-14.2
radical SAM protein
compare
MMJJ
_RS00195
-2.2
-3.9
precorrin-3B C(17)-methyltransferase
compare
MMJJ
_RS04975
-2.2
-2.1
glycosyltransferase family 4 protein
compare
MMJJ
_RS05950
-2.2
-3.7
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
compare
MMJJ
_RS07000
-2.1
-1.5
TrkH family potassium uptake protein
compare
MMJJ
_RS07275
-2.1
-3.6
formate--phosphoribosylaminoimidazolecarboxamide ligase
compare
MMJJ
_RS03060
-2.1
-2.9
methanogenesis marker 7 protein
compare
MMJJ
_RS00475
-2.1
-2.3
bifunctional ornithine acetyltransferase/N-acetylglutamate synthase
compare
MMJJ
_RS00530
-2.1
-12.0
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS01865
-2.0
-6.6
peptidyl-tRNA hydrolase Pth2
compare
MMJJ
_RS00065
-2.0
-11.0
4Fe-4S dicluster domain-containing protein
compare
MMJJ
_RS06930
-2.0
-2.2
type II methionyl aminopeptidase
compare
MMJJ
_RS05720
-2.0
-2.7
glutamine--fructose-6-phosphate transaminase (isomerizing)
compare
MMJJ
_RS00045
-2.0
-12.8
CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
compare
MMJJ
_RS00040
-1.9
-7.5
CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
compare
MMJJ
_RS00060
-1.9
-13.1
acetyl-CoA decarbonylase/synthase complex subunit gamma
compare
MMJJ
_RS00035
-1.9
-12.9
CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
compare
MMJJ
_RS08870
-1.9
-1.6
2-isopropylmalate synthase
compare
MMJJ
_RS08535
-1.9
-3.4
NOL1/NOP2/sun family putative RNA methylase
compare
MMJJ
_RS07345
-1.9
-5.6
homocysteine biosynthesis protein
compare
MMJJ
_RS04615
-1.9
-3.6
methanogenesis marker 3 protein
compare
MMJJ
_RS04985
-1.9
-4.1
glutamyl-tRNA reductase
compare
MMJJ
_RS06050
-1.9
-8.2
molybdopterin molybdotransferase MoeA
compare
MMJJ
_RS06865
-1.9
-2.7
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS08065
-1.9
-2.6
precorrin-6Y C5,15-methyltransferase (decarboxylating) subunit CbiT
compare
MMJJ
_RS05810
-1.9
-5.5
precorrin-4 C(11)-methyltransferase
compare
MMJJ
_RS00070
-1.9
-4.5
CooT family nickel-binding protein
compare
MMJJ
_RS07720
-1.9
-2.5
UPF0058 family protein
compare
MMJJ
_RS06380
-1.9
-3.6
signal recognition particle protein Srp54
compare
MMJJ
_RS05295
-1.9
-8.2
cobyrinic acid a,c-diamide synthase
compare
MMJJ
_RS04875
-1.9
-2.0
tRNA-Lys
compare
MMJJ
_RS00055
-1.9
-8.1
CO dehydrogenase/acetyl-CoA synthase subunit delta
compare
MMJJ
_RS00080
-1.9
-10.5
DUF166 domain-containing protein
compare
MMJJ
_RS08840
-1.9
-4.3
calcium/sodium antiporter
compare
MMJJ
_RS05225
-1.9
-2.1
Gar1/Naf1 family protein
compare
MMJJ
_RS03125
-1.8
-3.1
GMC oxidoreductase
compare
MMJJ
_RS00270
-1.8
-3.2
adenosylcobinamide-GDP ribazoletransferase
compare
MMJJ
_RS04970
-1.8
-2.0
DUF655 domain-containing protein
compare
MMJJ
_RS04110
-1.8
-4.5
hypothetical protein
compare
MMJJ
_RS02935
-1.8
-3.6
DNA-directed RNA polymerase subunit E''
compare
MMJJ
_RS05155
-1.8
-6.2
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH
compare
MMJJ
_RS05540
-1.8
-13.3
LysR family transcriptional regulator
compare
MMJJ
_RS03500
-1.8
-11.2
F420-dependent methylenetetrahydromethanopterin dehydrogenase
compare
MMJJ
_RS08620
-1.8
-3.4
DUF373 family protein
compare
MMJJ
_RS06185
-1.8
-5.2
cobalamin biosynthesis protein
compare
MMJJ
_RS00075
-1.8
-9.0
AAA family ATPase
compare
MMJJ
_RS03160
-1.8
-11.7
winged helix-turn-helix transcriptional regulator
compare
MMJJ
_RS00125
-1.8
-1.9
KEOPS complex subunit Cgi121
compare
MMJJ
_RS07785
-1.7
-2.4
fumarate reductase subunit A
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments