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Experiment set3IT059 for
Methanococcus maripaludis JJ
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formate McAA p-aminobenzoic acid dropout
200 most detrimental genes:
gene
name
fitness
t score
description
MMJJ
_RS04415
+2.5
15.7
hypothetical protein
compare
MMJJ
_RS08130
+1.3
1.6
translation initiation factor IF-2 subunit gamma
compare
MMJJ
_RS03725
+1.1
2.0
sulfurtransferase TusA family protein
compare
MMJJ
_RS04005
+1.0
7.4
acetate--CoA ligase family protein
compare
MMJJ
_RS09120
+0.8
2.2
aspartate kinase
compare
MMJJ
_RS04965
+0.7
2.1
RNA polymerase Rpb4 family protein
compare
MMJJ
_RS05280
+0.7
0.8
hypothetical protein
compare
MMJJ
_RS04545
+0.7
2.2
PadR family transcriptional regulator
compare
MMJJ
_RS06680
+0.7
3.9
DUF366 family protein
compare
MMJJ
_RS03250
+0.7
1.5
DUF2116 family Zn-ribbon domain-containing protein
compare
MMJJ
_RS06505
+0.7
2.6
prephenate dehydratase
compare
MMJJ
_RS05685
+0.6
4.3
class III signal peptide-containing protein
compare
MMJJ
_RS03835
+0.6
3.6
DUF504 domain-containing protein
compare
MMJJ
_RS03375
+0.6
3.7
hypothetical protein
compare
MMJJ
_RS07185
+0.6
3.0
DUF371 domain-containing protein
compare
MMJJ
_RS07240
+0.6
5.1
MBL fold metallo-hydrolase
compare
MMJJ
_RS07025
+0.6
2.7
tRNA (cytidine(56)-2'-O)-methyltransferase
compare
MMJJ
_RS06500
+0.6
4.2
class I SAM-dependent methyltransferase
compare
MMJJ
_RS07220
+0.6
4.4
coenzyme F420 hydrogenase subunit beta
compare
MMJJ
_RS01530
+0.5
1.0
YwbE family protein
compare
MMJJ
_RS07225
+0.5
3.7
coenzyme F420 hydrogenase subunit gamma
compare
MMJJ
_RS08830
+0.5
2.7
hypothetical protein
compare
MMJJ
_RS06540
+0.5
1.5
DUF2120 domain-containing protein
compare
MMJJ
_RS06090
+0.5
3.1
hypothetical protein
compare
MMJJ
_RS06460
+0.5
3.4
cytochrome c
compare
MMJJ
_RS04610
+0.5
2.2
ribosome assembly RNA-binding protein YhbY
compare
MMJJ
_RS07235
+0.5
4.1
coenzyme F420 hydrogenase subunit alpha
compare
MMJJ
_RS06950
+0.5
3.2
4-demethylwyosine synthase TYW1
compare
MMJJ
_RS06190
+0.5
3.8
7-cyano-7-deazaguanine synthase
compare
MMJJ
_RS03775
+0.5
1.9
50S ribosomal protein L15e
compare
MMJJ
_RS01855
+0.5
3.5
MBL fold metallo-hydrolase
compare
MMJJ
_RS04955
+0.5
3.1
tRNA pseudouridine(54/55) synthase Pus10
compare
MMJJ
_RS06385
+0.5
1.9
hypothetical protein
compare
MMJJ
_RS07280
+0.5
2.4
phosphomannomutase/phosphoglucomutase
compare
MMJJ
_RS07920
+0.5
3.1
6-carboxytetrahydropterin synthase QueD
compare
MMJJ
_RS07230
+0.5
2.7
coenzyme F420-reducing hydrogenase, FrhD protein
compare
MMJJ
_RS06515
+0.4
3.6
ribonuclease III
compare
MMJJ
_RS08485
+0.4
1.7
Lrp/AsnC family transcriptional regulator
compare
MMJJ
_RS06440
+0.4
2.9
DUF4870 domain-containing protein
compare
MMJJ
_RS07210
+0.4
3.4
AmmeMemoRadiSam system protein B
compare
MMJJ
_RS06275
+0.4
1.7
hypothetical protein
compare
MMJJ
_RS06810
+0.4
3.3
L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha
compare
MMJJ
_RS06685
+0.4
3.6
S-layer protein
compare
MMJJ
_RS06470
+0.4
3.3
tripartite tricarboxylate transporter permease
compare
MMJJ
_RS06675
+0.4
2.9
TIGR01212 family radical SAM protein
compare
MMJJ
_RS06210
+0.4
2.1
hypothetical protein
compare
MMJJ
_RS05975
+0.4
2.6
sulfurtransferase TusA family protein
compare
MMJJ
_RS05040
+0.4
2.7
7-carboxy-7-deazaguanine synthase QueE
compare
MMJJ
_RS06770
+0.4
3.2
hypothetical protein
compare
MMJJ
_RS05530
+0.4
1.7
roadblock/LC7 domain-containing protein
compare
MMJJ
_RS06535
+0.4
3.1
UPF0104 family protein
compare
MMJJ
_RS05915
+0.4
1.7
multiprotein bridging factor aMBF1
compare
MMJJ
_RS06735
+0.4
2.3
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS04105
+0.4
2.9
prepilin peptidase
compare
MMJJ
_RS06800
+0.4
1.7
prefoldin subunit alpha
compare
MMJJ
_RS01970
+0.4
1.7
hypothetical protein
compare
MMJJ
_RS06790
+0.4
2.9
nucleotidyltransferase family protein
compare
MMJJ
_RS06445
+0.3
2.9
hypothetical protein
compare
MMJJ
_RS03515
+0.3
2.1
GPR1/FUN34/YaaH family transporter
compare
MMJJ
_RS06710
+0.3
2.6
TldD/PmbA family protein
compare
MMJJ
_RS06960
+0.3
2.9
CAP domain-containing protein
compare
MMJJ
_RS04375
+0.3
0.8
hypothetical protein
compare
MMJJ
_RS06205
+0.3
2.4
EamA family transporter
compare
MMJJ
_RS06280
+0.3
2.4
hypothetical protein
compare
MMJJ
_RS08100
+0.3
1.7
hypothetical protein
compare
MMJJ
_RS07915
+0.3
1.6
CBS domain-containing protein
compare
MMJJ
_RS06640
+0.3
2.0
YfcE family phosphodiesterase
compare
MMJJ
_RS03805
+0.3
1.1
hypothetical protein
compare
MMJJ
_RS06520
+0.3
2.2
TldD/PmbA family protein
compare
MMJJ
_RS07270
+0.3
2.1
ribonuclease HII
compare
MMJJ
_RS02180
+0.3
1.6
DHH family phosphoesterase
compare
MMJJ
_RS07890
+0.3
2.1
pyrimidine dimer DNA glycosylase/endonuclease V
compare
MMJJ
_RS04815
+0.3
1.7
TIM barrel protein
compare
MMJJ
_RS06430
+0.3
1.8
haloacid dehalogenase
compare
MMJJ
_RS06745
+0.3
1.7
energy-coupling factor ABC transporter permease
compare
MMJJ
_RS07450
+0.3
1.5
hypothetical protein
compare
MMJJ
_RS05390
+0.3
2.3
tRNA pseudouridine(13) synthase TruD
compare
MMJJ
_RS05520
+0.3
2.0
H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein
compare
MMJJ
_RS04345
+0.3
1.3
DUF2080 family transposase-associated protein
compare
MMJJ
_RS08455
+0.3
1.4
tetratricopeptide repeat protein
compare
MMJJ
_RS07010
+0.3
1.6
preprotein translocase subunit Sec61beta
compare
MMJJ
_RS07795
+0.3
1.6
cupin domain-containing protein
compare
MMJJ
_RS08165
+0.3
1.7
thermonuclease family protein
compare
MMJJ
_RS07985
+0.3
1.4
hypothetical protein
compare
MMJJ
_RS06580
+0.3
2.1
alanine dehydrogenase
compare
MMJJ
_RS05815
+0.3
1.2
hypothetical protein
compare
MMJJ
_RS09380
+0.3
1.1
hypothetical protein
compare
MMJJ
_RS03350
+0.3
0.7
hypothetical protein
compare
MMJJ
_RS06045
+0.3
1.6
hypothetical protein
compare
MMJJ
_RS07800
+0.3
2.1
AMP-binding protein
compare
MMJJ
_RS07215
+0.3
2.2
TIGR00341 family protein
compare
MMJJ
_RS07815
+0.3
1.8
2-oxoacid:acceptor oxidoreductase family protein
compare
MMJJ
_RS05990
+0.3
1.7
phosphatase PAP2 family protein
compare
MMJJ
_RS05895
+0.3
2.2
ABC transporter permease
compare
MMJJ
_RS07260
+0.3
1.9
PspC domain-containing protein
compare
MMJJ
_RS07445
+0.3
1.8
RlmF-related methyltransferase
compare
MMJJ
_RS03360
+0.3
0.4
hypothetical protein
compare
MMJJ
_RS07765
+0.3
0.9
DMT family protein
compare
MMJJ
_RS06120
+0.3
1.9
DUF4013 domain-containing protein
compare
MMJJ
_RS09300
+0.3
0.8
hypothetical protein
compare
MMJJ
_RS07365
+0.3
1.9
CatB-related O-acetyltransferase
compare
MMJJ
_RS03450
+0.3
1.5
hypothetical protein
compare
MMJJ
_RS05500
+0.2
2.2
hypothetical protein
compare
MMJJ
_RS00145
+0.2
2.0
aquaporin family protein
compare
MMJJ
_RS07015
+0.2
0.4
PFL family protein
compare
MMJJ
_RS03575
+0.2
1.1
NUDIX hydrolase
compare
MMJJ
_RS05580
+0.2
1.5
methanogenesis marker 9 domain-containing protein
compare
MMJJ
_RS04500
+0.2
1.5
hypothetical protein
compare
MMJJ
_RS02270
+0.2
1.2
HEPN domain-containing protein
compare
MMJJ
_RS06115
+0.2
1.7
pyruvate kinase
compare
MMJJ
_RS05605
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS05970
+0.2
0.9
MJ0307 family thioredoxin
compare
MMJJ
_RS01955
+0.2
2.0
hypothetical protein
compare
MMJJ
_RS05200
+0.2
1.8
TIGR04013 family B12-binding domain/radical SAM domain-containing protein
compare
MMJJ
_RS00745
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS06235
+0.2
1.9
IGHMBP2 family helicase
compare
MMJJ
_RS04365
+0.2
1.4
helix-turn-helix transcriptional regulator
compare
MMJJ
_RS03290
+0.2
1.9
amidohydrolase
compare
MMJJ
_RS04215
+0.2
1.9
DMT family transporter
compare
MMJJ
_RS02665
+0.2
0.7
methyl-accepting chemotaxis protein
compare
MMJJ
_RS08160
+0.2
1.4
tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO
compare
MMJJ
_RS01300
+0.2
1.5
MarR family transcriptional regulator
compare
MMJJ
_RS07255
+0.2
1.9
hypothetical protein
compare
MMJJ
_RS06765
+0.2
1.9
hypothetical protein
compare
MMJJ
_RS06455
+0.2
1.7
YeeE/YedE family protein
compare
MMJJ
_RS02285
+0.2
0.6
class III signal peptide-containing protein
compare
MMJJ
_RS01745
+0.2
1.0
metal-dependent transcriptional regulator
compare
MMJJ
_RS06130
+0.2
1.2
hypothetical protein
compare
MMJJ
_RS03510
+0.2
1.3
acyl-CoA dehydratase activase
compare
MMJJ
_RS06590
+0.2
1.7
sodium:alanine symporter family protein
compare
MMJJ
_RS05660
+0.2
1.5
sulfopyruvate decarboxylase subunit beta
compare
MMJJ
_RS08525
+0.2
1.3
peptidylprolyl isomerase
compare
MMJJ
_RS05665
+0.2
1.5
hypothetical protein
compare
MMJJ
_RS09325
+0.2
1.2
hypothetical protein
compare
MMJJ
_RS07200
+0.2
1.6
MFS transporter
compare
MMJJ
_RS06585
+0.2
1.5
alanine racemase
compare
MMJJ
_RS05690
+0.2
1.9
hypothetical protein
compare
MMJJ
_RS07835
+0.2
1.3
UPF0489 family protein
compare
MMJJ
_RS00150
+0.2
1.0
DUF2180 family protein
compare
MMJJ
_RS05410
+0.2
1.3
RecB-family nuclease
compare
MMJJ
_RS07905
+0.2
1.3
DUF89 domain-containing protein
compare
MMJJ
_RS06055
+0.2
1.3
S-methyl-5-thioribose-1-phosphate isomerase
compare
MMJJ
_RS08515
+0.2
1.0
secondary thiamine-phosphate synthase enzyme YjbQ
compare
MMJJ
_RS06550
+0.2
1.4
ABC transporter permease
compare
MMJJ
_RS02170
+0.2
1.5
2-thiouracil desulfurase family protein
compare
MMJJ
_RS08305
+0.2
0.9
peroxiredoxin
compare
MMJJ
_RS07005
+0.2
1.1
transcription factor S
compare
MMJJ
_RS08310
+0.2
1.2
ZIP family metal transporter
compare
MMJJ
_RS03220
+0.2
1.6
inosine/xanthosine triphosphatase
compare
MMJJ
_RS04340
+0.2
0.5
hypothetical protein
compare
MMJJ
_RS07740
+0.2
1.3
DUF2334 domain-containing protein
compare
MMJJ
_RS07175
+0.2
1.5
DEAD/DEAH box helicase
compare
MMJJ
_RS02160
+0.2
1.3
amino acid ABC transporter permease
compare
MMJJ
_RS05355
+0.2
1.4
DUF2121 domain-containing protein
compare
MMJJ
_RS05695
+0.2
0.6
class III signal peptide-containing protein
compare
MMJJ
_RS08195
+0.2
1.4
DUF4186 domain-containing protein
compare
MMJJ
_RS05700
+0.2
1.2
metallophosphoesterase
compare
MMJJ
_RS06555
+0.2
1.4
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS02330
+0.2
1.5
ABC transporter ATP-binding protein
compare
MMJJ
_RS01010
+0.2
1.7
right-handed parallel beta-helix repeat-containing protein
compare
MMJJ
_RS02860
+0.2
0.6
site-specific integrase
compare
MMJJ
_RS05235
+0.2
1.6
Flp pilus assembly complex ATPase component TadA
compare
MMJJ
_RS06560
+0.2
1.4
site-2 protease family protein
compare
MMJJ
_RS01035
+0.2
0.8
hypothetical protein
compare
MMJJ
_RS04625
+0.2
1.3
SLC13 family permease
compare
MMJJ
_RS00400
+0.2
0.6
tautomerase family protein
compare
MMJJ
_RS07810
+0.2
1.2
3-methyl-2-oxobutanoate dehydrogenase subunit VorB
compare
MMJJ
_RS05715
+0.2
1.3
phosphoadenosine phosphosulfate reductase family protein
compare
MMJJ
_RS01395
+0.2
0.8
DUF1894 domain-containing protein
compare
MMJJ
_RS04390
+0.2
1.5
rhomboid family intramembrane serine protease
compare
MMJJ
_RS05405
+0.2
1.4
DNA cytosine methyltransferase
compare
MMJJ
_RS08520
+0.2
0.6
peptidylprolyl isomerase
compare
MMJJ
_RS07480
+0.2
1.3
FAD-dependent oxidoreductase
compare
MMJJ
_RS07385
+0.2
1.2
ribosomal protein S18-alanine N-acetyltransferase
compare
MMJJ
_RS07860
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS06100
+0.2
1.2
rubrerythrin
compare
MMJJ
_RS02125
+0.2
0.8
hypothetical protein
compare
MMJJ
_RS01790
+0.2
1.1
pyridoxamine 5'-phosphate oxidase family protein
compare
MMJJ
_RS08285
+0.2
1.2
class I SAM-dependent methyltransferase
compare
MMJJ
_RS02905
+0.2
0.6
NifB/NifX family molybdenum-iron cluster-binding protein
compare
MMJJ
_RS07495
+0.2
1.0
4Fe-4S binding protein
compare
MMJJ
_RS04420
+0.2
1.3
type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family
compare
MMJJ
_RS05980
+0.2
0.9
DUF5400 domain-containing protein
compare
MMJJ
_RS06450
+0.2
1.2
DUF3343 domain-containing protein
compare
MMJJ
_RS09255
+0.2
0.7
hypothetical protein
compare
MMJJ
_RS06080
+0.2
1.1
serine/threonine protein kinase
compare
MMJJ
_RS03285
+0.2
0.8
gamma-glutamylcyclotransferase
compare
MMJJ
_RS07685
+0.2
1.3
glycogen/starch synthase
compare
MMJJ
_RS03025
+0.2
1.3
Ig-like domain-containing protein
compare
MMJJ
_RS08210
+0.2
1.5
hypothetical protein
compare
MMJJ
_RS06465
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS00555
+0.1
1.0
hypothetical protein
compare
MMJJ
_RS01510
+0.1
0.9
ATP-binding protein
compare
MMJJ
_RS08370
+0.1
0.6
hypothetical protein
compare
MMJJ
_RS04510
+0.1
1.2
hypothetical protein
compare
MMJJ
_RS07695
+0.1
1.2
glycoside hydrolase family 15 protein
compare
MMJJ
_RS00890
+0.1
1.1
coenzyme F420 hydrogenase subunit gamma
compare
MMJJ
_RS08255
+0.1
1.0
GNAT family N-acetyltransferase
compare
MMJJ
_RS08670
+0.1
1.0
phosphate signaling complex protein PhoU
compare
MMJJ
_RS01835
+0.1
1.2
tRNA pseudouridine(13) synthase TruD
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments