Experiment set3IT058 for Methanococcus maripaludis JJ

Compare to:

formate McAA p-aminobenzoic acid dropout

200 most important genes:

  gene name fitness t score description  
MMJJ_RS00235 -6.1 -24.1 hypothetical protein compare
MMJJ_RS06625 -5.3 -3.4 pyruvate synthase subunit PorB compare
MMJJ_RS04485 -5.2 -11.1 riboflavin synthase compare
MMJJ_RS08250 -5.0 -6.8 hydrogenase maturation peptidase HycI compare
MMJJ_RS07720 -5.0 -3.0 UPF0058 family protein compare
MMJJ_RS04200 -4.9 -9.3 triphosphoribosyl-dephospho-CoA synthase compare
MMJJ_RS05450 -4.7 -17.5 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMJJ_RS01810 -4.7 -3.2 methyl coenzyme M reductase system, component A2 compare
MMJJ_RS00450 -4.6 -2.9 DUF126 domain-containing protein compare
MMJJ_RS06855 -4.5 -2.3 DUF2104 domain-containing protein compare
MMJJ_RS05930 -4.5 -3.1 cell division protein SepF compare
MMJJ_RS03615 -4.4 -5.2 cobalt-precorrin-8 methylmutase compare
MMJJ_RS06040 -4.4 -5.9 NADH-quinone oxidoreductase subunit H compare
MMJJ_RS03200 -4.3 -2.9 uroporphyrinogen-III synthase compare
MMJJ_RS05950 -4.3 -4.1 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase compare
MMJJ_RS06240 -4.2 -4.5 dihydropteroate synthase-like protein compare
MMJJ_RS06490 -4.2 -4.0 methanogenesis marker 2 protein compare
MMJJ_RS09130 -4.2 -2.6 NFYB/HAP3 family transcription factor subunit compare
MMJJ_RS00270 -4.2 -4.9 adenosylcobinamide-GDP ribazoletransferase compare
MMJJ_RS06860 -4.1 -6.3 hypothetical protein compare
MMJJ_RS02045 -4.1 -5.6 molybdenum cofactor guanylyltransferase compare
MMJJ_RS05535 -4.1 -17.8 hypothetical protein compare
MMJJ_RS04475 -4.0 -5.8 3,4-dihydroxy-2-butanone-4-phosphate synthase compare
MMJJ_RS04995 -4.0 -8.0 Tfx family DNA-binding protein compare
MMJJ_RS00215 -4.0 -3.7 CCA tRNA nucleotidyltransferase compare
MMJJ_RS00275 -3.8 -3.8 coenzyme F420-0:L-glutamate ligase compare
MMJJ_RS02920 -3.8 -3.6 30S ribosomal protein S27ae compare
MMJJ_RS07665 -3.8 -22.9 formate dehydrogenase subunit alpha compare
MMJJ_RS02275 -3.8 -6.7 nucleotidyltransferase domain-containing protein compare
MMJJ_RS06840 -3.7 -5.0 nickel-dependent hydrogenase large subunit compare
MMJJ_RS06880 -3.7 -2.4 EhaG family protein compare
MMJJ_RS08320 -3.7 -3.4 CDP-diacylglycerol--serine O-phosphatidyltransferase compare
MMJJ_RS06875 -3.7 -4.1 hypothetical protein compare
MMJJ_RS03580 -3.7 -4.8 TIGR00303 family protein compare
MMJJ_RS07470 -3.7 -3.0 50S ribosome-binding GTPase compare
MMJJ_RS04155 -3.7 -9.3 hypothetical protein compare
MMJJ_RS01600 -3.6 -4.3 radical SAM protein compare
MMJJ_RS00475 -3.6 -3.0 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase compare
MMJJ_RS06905 -3.6 -3.7 hypothetical protein compare
MMJJ_RS07380 -3.6 -11.0 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMJJ_RS08000 -3.6 -12.1 HesA/MoeB/ThiF family protein compare
MMJJ_RS03840 -3.6 -5.4 DHH family phosphoesterase compare
MMJJ_RS01935 -3.6 -6.5 O-phosphoseryl-tRNA(Sec) selenium transferase compare
MMJJ_RS05650 -3.6 -4.0 formylmethanofuran dehydrogenase subunit B compare
MMJJ_RS00570 -3.6 -3.0 ribonuclease P compare
MMJJ_RS06785 -3.5 -8.7 RNA ligase partner protein compare
MMJJ_RS05620 -3.5 -5.8 CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein compare
MMJJ_RS03760 -3.5 -5.1 hydrogenase maturation nickel metallochaperone HypA compare
MMJJ_RS07670 -3.5 -17.9 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain compare
MMJJ_RS09175 -3.5 -2.2 anthranilate synthase component I compare
MMJJ_RS04790 -3.5 -6.4 biotin--[acetyl-CoA-carboxylase] ligase compare
MMJJ_RS01755 -3.4 -3.3 ferrous iron transport protein B compare
MMJJ_RS08625 -3.4 -8.9 magnesium/cobalt transporter CorA compare
MMJJ_RS08330 -3.4 -5.1 SufD family Fe-S cluster assembly protein compare
MMJJ_RS02090 -3.4 -8.0 tyramine--L-glutamate ligase compare
MMJJ_RS04800 -3.4 -7.4 2-phospho-L-lactate guanylyltransferase compare
MMJJ_RS08080 -3.4 -12.4 TIGR00300 family protein compare
MMJJ_RS06255 -3.3 -8.8 tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3 compare
MMJJ_RS05575 -3.3 -6.6 2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase compare
MMJJ_RS03820 -3.3 -5.4 hydrogenase formation protein HypD compare
MMJJ_RS05995 -3.3 -4.3 ATP-binding cassette domain-containing protein compare
MMJJ_RS06705 -3.3 -6.9 bifunctional NADP phosphatase/NAD kinase compare
MMJJ_RS08020 -3.3 -9.3 nucleotidyltransferase domain-containing protein compare
MMJJ_RS06725 -3.3 -15.7 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMJJ_RS03270 -3.3 -3.4 ribosome biogenesis/translation initiation ATPase RLI compare
MMJJ_RS06915 -3.3 -16.4 helix-turn-helix domain-containing protein compare
MMJJ_RS03785 -3.3 -3.8 hypothetical protein compare
MMJJ_RS05445 -3.3 -2.5 2-oxoacid:acceptor oxidoreductase subunit alpha compare
MMJJ_RS01565 -3.2 -8.3 TIGR00267 family protein compare
MMJJ_RS04520 -3.2 -8.4 coenzyme F430 synthase compare
MMJJ_RS07655 -3.2 -16.5 hypothetical protein compare
MMJJ_RS07350 -3.2 -5.2 4Fe-4S binding protein compare
MMJJ_RS05610 -3.2 -6.2 CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMJJ_RS05070 -3.2 -3.0 DNA primase catalytic subunit PriS compare
MMJJ_RS03670 -3.2 -5.7 precorrin-2 C(20)-methyltransferase compare
MMJJ_RS06510 -3.1 -4.9 LL-diaminopimelate aminotransferase compare
MMJJ_RS03065 -3.1 -13.8 CBS domain-containing protein compare
MMJJ_RS00370 -3.1 -2.5 asparagine synthase (glutamine-hydrolyzing) compare
MMJJ_RS08055 -3.1 -8.5 methanogenesis marker 14 protein compare
MMJJ_RS03895 -3.1 -4.2 hydrogenase expression/formation protein HypE compare
MMJJ_RS04975 -3.1 -2.9 glycosyltransferase family 4 protein compare
MMJJ_RS01360 -3.1 -3.5 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMJJ_RS09190 -3.1 -2.8 tryptophan synthase subunit beta compare
MMJJ_RS06180 -3.1 -4.1 tryptophan--tRNA ligase compare
MMJJ_RS03150 -3.0 -7.8 2-phospho-L-lactate transferase compare
MMJJ_RS08005 -3.0 -16.8 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMJJ_RS04685 -3.0 -9.7 carbamoyltransferase HypF compare
MMJJ_RS04730 -3.0 -3.7 tyrosine decarboxylase MfnA compare
MMJJ_RS01415 -3.0 -3.7 beta-CASP ribonuclease aCPSF1 compare
MMJJ_RS05490 -3.0 -3.6 imidazole glycerol phosphate synthase subunit HisF compare
MMJJ_RS06185 -2.9 -6.7 cobalamin biosynthesis protein compare
MMJJ_RS05810 -2.9 -8.6 precorrin-4 C(11)-methyltransferase compare
MMJJ_RS03865 -2.9 -2.6 phosphoribosyl-AMP cyclohydrolase compare
MMJJ_RS07950 -2.9 -4.6 4Fe-4S binding protein compare
MMJJ_RS06910 -2.9 -4.0 energy-converting NiFe hydrogenase A subunit EhaA compare
MMJJ_RS07660 -2.9 -10.7 carbonic anhydrase compare
MMJJ_RS07705 -2.9 -3.8 GTP-binding protein EngB compare
MMJJ_RS08660 -2.9 -4.3 acetylornithine transaminase compare
MMJJ_RS08535 -2.9 -5.0 NOL1/NOP2/sun family putative RNA methylase compare
MMJJ_RS05655 -2.8 -7.2 HisA/HisF family protein compare
MMJJ_RS03095 -2.8 -3.5 bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase compare
MMJJ_RS03620 -2.8 -6.5 DUF2097 domain-containing protein compare
MMJJ_RS06390 -2.8 -2.5 NADPH-dependent F420 reductase compare
MMJJ_RS00070 -2.8 -5.9 CooT family nickel-binding protein compare
MMJJ_RS01345 -2.7 -5.0 (5-formylfuran-3-yl)methyl phosphate synthase compare
MMJJ_RS03295 -2.7 -17.0 PHP domain-containing protein compare
MMJJ_RS07245 -2.7 -6.1 amidohydrolase family protein compare
MMJJ_RS08840 -2.7 -5.9 calcium/sodium antiporter compare
MMJJ_RS06375 -2.7 -5.9 UbiX family flavin prenyltransferase compare
MMJJ_RS06485 -2.6 -4.5 phosphoglycerate kinase compare
MMJJ_RS08340 -2.6 -6.5 archaeoflavoprotein AfpA compare
MMJJ_RS00520 -2.5 -6.2 PDGLE domain-containing protein compare
MMJJ_RS06695 -2.5 -3.2 amidohydrolase compare
MMJJ_RS06220 -2.5 -7.7 polyamine aminopropyltransferase compare
MMJJ_RS03055 -2.5 -3.8 hypothetical protein compare
MMJJ_RS05415 -2.5 -2.3 hypothetical protein compare
MMJJ_RS01865 -2.5 -6.5 peptidyl-tRNA hydrolase Pth2 compare
MMJJ_RS02935 -2.5 -3.7 DNA-directed RNA polymerase subunit E'' compare
MMJJ_RS03830 -2.5 -10.7 CBS domain-containing protein compare
MMJJ_RS08325 -2.5 -2.9 glycosyltransferase family 2 protein compare
MMJJ_RS05260 -2.4 -5.4 ATP-grasp domain-containing protein compare
MMJJ_RS00600 -2.4 -3.8 hydroxymethylbilane synthase compare
MMJJ_RS06215 -2.4 -6.4 agmatinase compare
MMJJ_RS03005 -2.4 -4.6 Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit compare
MMJJ_RS07725 -2.4 -7.5 DNA primase DnaG compare
MMJJ_RS05190 -2.4 -7.1 gamma carbonic anhydrase family protein compare
MMJJ_RS00040 -2.4 -10.8 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMJJ_RS06250 -2.4 -3.0 nicotinamide-nucleotide adenylyltransferase compare
MMJJ_RS03110 -2.4 -4.3 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase compare
MMJJ_RS05360 -2.4 -6.0 nickel-responsive transcriptional regulator NikR compare
MMJJ_RS06835 -2.4 -11.7 4Fe-4S binding protein compare
MMJJ_RS05375 -2.4 -15.4 radical SAM protein compare
MMJJ_RS07000 -2.4 -2.5 TrkH family potassium uptake protein compare
MMJJ_RS07945 -2.3 -3.1 4Fe-4S binding protein compare
MMJJ_RS04655 -2.3 -5.3 FAD-dependent oxidoreductase compare
MMJJ_RS07785 -2.3 -3.4 fumarate reductase subunit A compare
MMJJ_RS00355 -2.3 -4.5 ribonuclease P protein component 4 compare
MMJJ_RS01200 -2.3 -3.7 PRC-barrel domain-containing protein compare
MMJJ_RS01750 -2.3 -3.6 ferrous iron transport protein A compare
MMJJ_RS00210 -2.3 -2.7 DUF530 family protein compare
MMJJ_RS00125 -2.3 -3.4 KEOPS complex subunit Cgi121 compare
MMJJ_RS00050 -2.3 -12.8 AAA family ATPase compare
MMJJ_RS04675 -2.3 -5.3 thiamine pyrophosphate-binding protein compare
MMJJ_RS00530 -2.3 -12.1 cobalt ECF transporter T component CbiQ compare
MMJJ_RS03875 -2.3 -5.5 CBS domain-containing protein compare
MMJJ_RS00560 -2.3 -3.5 homoisocitrate dehydrogenase compare
MMJJ_RS07635 -2.2 -13.6 response regulator transcription factor compare
MMJJ_RS08855 -2.2 -6.0 cyclic pyranopterin monophosphate synthase MoaC compare
MMJJ_RS06225 -2.2 -2.4 adenosylmethionine decarboxylase compare
MMJJ_RS03800 -2.2 -9.8 aldolase compare
MMJJ_RS08620 -2.2 -3.6 DUF373 family protein compare
MMJJ_RS00580 -2.2 -2.7 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG compare
MMJJ_RS06930 -2.2 -2.9 type II methionyl aminopeptidase compare
MMJJ_RS07370 -2.2 -4.6 tRNA 4-thiouridine(8) synthase ThiI compare
MMJJ_RS06760 -2.2 -5.6 Ni-sirohydrochlorin a,c-diamide synthase compare
MMJJ_RS09375 -2.2 -2.4 hypothetical protein compare
MMJJ_RS05295 -2.2 -9.7 cobyrinic acid a,c-diamide synthase compare
MMJJ_RS00515 -2.2 -11.6 cobalt transporter CbiM compare
MMJJ_RS00045 -2.2 -10.7 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMJJ_RS06155 -2.1 -4.9 phosphatidylglycerophosphatase A compare
MMJJ_RS07875 -2.1 -2.4 FAD-dependent oxidoreductase compare
MMJJ_RS03190 -2.1 -3.5 phosphopyruvate hydratase compare
MMJJ_RS07345 -2.1 -5.7 homocysteine biosynthesis protein compare
MMJJ_RS03630 -2.1 -9.7 AMP phosphorylase compare
MMJJ_RS03660 -2.1 -3.9 DUF447 family protein compare
MMJJ_RS01690 -2.1 -3.5 methanogenesis marker 12 protein compare
MMJJ_RS04970 -2.1 -2.2 DUF655 domain-containing protein compare
MMJJ_RS07640 -2.0 -16.4 cache domain-containing protein compare
MMJJ_RS00065 -2.0 -9.5 4Fe-4S dicluster domain-containing protein compare
MMJJ_RS05225 -2.0 -1.4 Gar1/Naf1 family protein compare
MMJJ_RS05935 -2.0 -2.8 Era-like GTP-binding protein compare
MMJJ_RS07355 -2.0 -5.3 MoaD/ThiS family protein compare
MMJJ_RS06380 -2.0 -4.1 signal recognition particle protein Srp54 compare
MMJJ_RS07650 -2.0 -14.0 formate/nitrite transporter family protein compare
MMJJ_RS07155 -2.0 -8.2 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMJJ_RS04050 -2.0 -1.6 dihydroneopterin aldolase family protein compare
MMJJ_RS06730 -2.0 -7.4 ATP-binding cassette domain-containing protein compare
MMJJ_RS07840 -2.0 -2.0 Glu-tRNA(Gln) amidotransferase subunit GatD compare
MMJJ_RS00035 -2.0 -13.4 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMJJ_RS00060 -2.0 -13.1 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMJJ_RS08795 -2.0 -3.0 phosphoglucosamine mutase compare
MMJJ_RS01880 -2.0 -4.0 RlmE family RNA methyltransferase compare
MMJJ_RS08155 -2.0 -5.0 cobalt-precorrin-5B (C(1))-methyltransferase CbiD compare
MMJJ_RS00195 -2.0 -3.2 precorrin-3B C(17)-methyltransferase compare
MMJJ_RS07995 -2.0 -7.3 molybdenum cofactor biosynthesis protein MoaE compare
MMJJ_RS06050 -2.0 -8.8 molybdopterin molybdotransferase MoeA compare
MMJJ_RS04985 -2.0 -4.0 glutamyl-tRNA reductase compare
MMJJ_RS01355 -1.9 -3.2 UDP-N-acetyl-D-mannosamine dehydrogenase compare
MMJJ_RS07410 -1.9 -3.5 methanogenesis marker protein Mmp4/MtxX compare
MMJJ_RS08095 -1.9 -4.3 cobyric acid synthase CobQ compare
MMJJ_RS07980 -1.9 -10.5 biotin synthase BioB compare
MMJJ_RS00055 -1.9 -8.1 CO dehydrogenase/acetyl-CoA synthase subunit delta compare
MMJJ_RS01870 -1.9 -2.4 methanogenesis marker 15 protein compare
MMJJ_RS08065 -1.9 -3.0 precorrin-6Y C5,15-methyltransferase (decarboxylating) subunit CbiT compare
MMJJ_RS06010 -1.9 -7.4 hypothetical protein compare
MMJJ_RS00075 -1.9 -9.5 AAA family ATPase compare
MMJJ_RS04010 -1.9 -7.2 archaeal proteasome endopeptidase complex subunit alpha compare
MMJJ_RS03125 -1.9 -3.0 GMC oxidoreductase compare
MMJJ_RS01830 -1.8 -3.3 tRNA(Ile)(2)-agmatinylcytidine synthase compare
MMJJ_RS05720 -1.8 -3.1 glutamine--fructose-6-phosphate transaminase (isomerizing) compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis JJ in nutrient t1 experiments