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Experiment set3IT058 for
Methanococcus maripaludis JJ
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formate McAA p-aminobenzoic acid dropout
200 most detrimental genes:
gene
name
fitness
t score
description
MMJJ
_RS04415
+2.7
17.3
hypothetical protein
compare
MMJJ
_RS04005
+0.8
6.0
acetate--CoA ligase family protein
compare
MMJJ
_RS08130
+0.8
0.9
translation initiation factor IF-2 subunit gamma
compare
MMJJ
_RS06505
+0.7
3.2
prephenate dehydratase
compare
MMJJ
_RS08830
+0.7
4.3
hypothetical protein
compare
MMJJ
_RS07240
+0.7
5.7
MBL fold metallo-hydrolase
compare
MMJJ
_RS06675
+0.7
4.9
TIGR01212 family radical SAM protein
compare
MMJJ
_RS07920
+0.6
4.1
6-carboxytetrahydropterin synthase QueD
compare
MMJJ
_RS07185
+0.6
2.3
DUF371 domain-containing protein
compare
MMJJ
_RS07025
+0.6
3.2
tRNA (cytidine(56)-2'-O)-methyltransferase
compare
MMJJ
_RS05040
+0.6
4.2
7-carboxy-7-deazaguanine synthase QueE
compare
MMJJ
_RS07935
+0.6
0.6
protein fwdD
compare
MMJJ
_RS03725
+0.5
1.5
sulfurtransferase TusA family protein
compare
MMJJ
_RS03835
+0.5
2.7
DUF504 domain-containing protein
compare
MMJJ
_RS01855
+0.5
3.9
MBL fold metallo-hydrolase
compare
MMJJ
_RS07230
+0.5
3.4
coenzyme F420-reducing hydrogenase, FrhD protein
compare
MMJJ
_RS07225
+0.5
3.7
coenzyme F420 hydrogenase subunit gamma
compare
MMJJ
_RS05685
+0.5
3.3
class III signal peptide-containing protein
compare
MMJJ
_RS07235
+0.5
4.3
coenzyme F420 hydrogenase subunit alpha
compare
MMJJ
_RS04375
+0.5
1.4
hypothetical protein
compare
MMJJ
_RS04955
+0.5
2.7
tRNA pseudouridine(54/55) synthase Pus10
compare
MMJJ
_RS08225
+0.5
2.0
peptidylprolyl isomerase
compare
MMJJ
_RS05780
+0.5
1.2
flagellin
compare
MMJJ
_RS04545
+0.5
2.0
PadR family transcriptional regulator
compare
MMJJ
_RS05580
+0.5
2.5
methanogenesis marker 9 domain-containing protein
compare
MMJJ
_RS06460
+0.4
3.1
cytochrome c
compare
MMJJ
_RS09365
+0.4
1.4
hypothetical protein
compare
MMJJ
_RS06515
+0.4
3.4
ribonuclease III
compare
MMJJ
_RS06090
+0.4
2.7
hypothetical protein
compare
MMJJ
_RS08515
+0.4
2.2
secondary thiamine-phosphate synthase enzyme YjbQ
compare
MMJJ
_RS05975
+0.4
2.4
sulfurtransferase TusA family protein
compare
MMJJ
_RS03360
+0.4
0.7
hypothetical protein
compare
MMJJ
_RS06540
+0.4
2.0
DUF2120 domain-containing protein
compare
MMJJ
_RS04105
+0.4
3.3
prepilin peptidase
compare
MMJJ
_RS03250
+0.4
1.5
DUF2116 family Zn-ribbon domain-containing protein
compare
MMJJ
_RS08100
+0.4
2.1
hypothetical protein
compare
MMJJ
_RS07985
+0.4
2.0
hypothetical protein
compare
MMJJ
_RS07260
+0.4
2.7
PspC domain-containing protein
compare
MMJJ
_RS01670
+0.4
1.3
hypothetical protein
compare
MMJJ
_RS06205
+0.4
2.8
EamA family transporter
compare
MMJJ
_RS06275
+0.4
2.3
hypothetical protein
compare
MMJJ
_RS01970
+0.4
2.0
hypothetical protein
compare
MMJJ
_RS06440
+0.4
2.7
DUF4870 domain-containing protein
compare
MMJJ
_RS07210
+0.4
2.9
AmmeMemoRadiSam system protein B
compare
MMJJ
_RS01825
+0.4
1.6
DNA repair and recombination protein RadB
compare
MMJJ
_RS08810
+0.4
0.5
DUF4040 domain-containing protein
compare
MMJJ
_RS01010
+0.4
3.5
right-handed parallel beta-helix repeat-containing protein
compare
MMJJ
_RS07915
+0.4
2.0
CBS domain-containing protein
compare
MMJJ
_RS03775
+0.4
1.0
50S ribosomal protein L15e
compare
MMJJ
_RS06470
+0.4
2.5
tripartite tricarboxylate transporter permease
compare
MMJJ
_RS03410
+0.4
1.5
hypothetical protein
compare
MMJJ
_RS06120
+0.4
2.5
DUF4013 domain-containing protein
compare
MMJJ
_RS06500
+0.4
2.0
class I SAM-dependent methyltransferase
compare
MMJJ
_RS07220
+0.3
2.8
coenzyme F420 hydrogenase subunit beta
compare
MMJJ
_RS06210
+0.3
1.8
hypothetical protein
compare
MMJJ
_RS07825
+0.3
1.3
YciI family protein
compare
MMJJ
_RS02270
+0.3
1.4
HEPN domain-containing protein
compare
MMJJ
_RS07795
+0.3
2.0
cupin domain-containing protein
compare
MMJJ
_RS05605
+0.3
1.5
hypothetical protein
compare
MMJJ
_RS06740
+0.3
2.0
energy-coupling factor ABC transporter substrate-binding protein
compare
MMJJ
_RS03515
+0.3
2.2
GPR1/FUN34/YaaH family transporter
compare
MMJJ
_RS06765
+0.3
2.6
hypothetical protein
compare
MMJJ
_RS03575
+0.3
1.5
NUDIX hydrolase
compare
MMJJ
_RS04610
+0.3
1.8
ribosome assembly RNA-binding protein YhbY
compare
MMJJ
_RS02665
+0.3
0.9
methyl-accepting chemotaxis protein
compare
MMJJ
_RS07505
+0.3
0.4
DNA-directed RNA polymerase subunit K
compare
MMJJ
_RS06685
+0.3
2.6
S-layer protein
compare
MMJJ
_RS07800
+0.3
2.4
AMP-binding protein
compare
MMJJ
_RS07270
+0.3
2.0
ribonuclease HII
compare
MMJJ
_RS06580
+0.3
2.3
alanine dehydrogenase
compare
MMJJ
_RS06710
+0.3
2.4
TldD/PmbA family protein
compare
MMJJ
_RS06190
+0.3
2.2
7-cyano-7-deazaguanine synthase
compare
MMJJ
_RS03375
+0.3
1.3
hypothetical protein
compare
MMJJ
_RS05335
+0.3
1.4
heavy metal-binding domain-containing protein
compare
MMJJ
_RS00400
+0.3
1.1
tautomerase family protein
compare
MMJJ
_RS06535
+0.3
2.2
UPF0104 family protein
compare
MMJJ
_RS08870
+0.3
0.4
2-isopropylmalate synthase
compare
MMJJ
_RS05915
+0.3
0.9
multiprotein bridging factor aMBF1
compare
MMJJ
_RS07740
+0.3
2.0
DUF2334 domain-containing protein
compare
MMJJ
_RS07815
+0.3
1.9
2-oxoacid:acceptor oxidoreductase family protein
compare
MMJJ
_RS06810
+0.3
2.2
L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha
compare
MMJJ
_RS06960
+0.3
2.3
CAP domain-containing protein
compare
MMJJ
_RS00145
+0.3
2.2
aquaporin family protein
compare
MMJJ
_RS06680
+0.3
1.7
DUF366 family protein
compare
MMJJ
_RS05660
+0.3
1.6
sulfopyruvate decarboxylase subunit beta
compare
MMJJ
_RS07035
+0.3
0.5
glycosyl transferase
compare
MMJJ
_RS07495
+0.3
1.6
4Fe-4S binding protein
compare
MMJJ
_RS06735
+0.3
1.8
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS01055
+0.3
1.6
hypothetical protein
compare
MMJJ
_RS04850
+0.3
1.6
energy-coupling factor transporter transmembrane protein EcfT
compare
MMJJ
_RS05960
+0.3
1.9
DUF169 domain-containing protein
compare
MMJJ
_RS06950
+0.3
1.7
4-demethylwyosine synthase TYW1
compare
MMJJ
_RS04215
+0.3
2.2
DMT family transporter
compare
MMJJ
_RS08305
+0.3
1.6
peroxiredoxin
compare
MMJJ
_RS06640
+0.3
1.7
YfcE family phosphodiesterase
compare
MMJJ
_RS05525
+0.2
1.6
GTP-binding protein
compare
MMJJ
_RS05530
+0.2
1.0
roadblock/LC7 domain-containing protein
compare
MMJJ
_RS05390
+0.2
1.9
tRNA pseudouridine(13) synthase TruD
compare
MMJJ
_RS07040
+0.2
0.4
preprotein translocase subunit SecY
compare
MMJJ
_RS01790
+0.2
1.7
pyridoxamine 5'-phosphate oxidase family protein
compare
MMJJ
_RS06550
+0.2
1.8
ABC transporter permease
compare
MMJJ
_RS06790
+0.2
2.0
nucleotidyltransferase family protein
compare
MMJJ
_RS08165
+0.2
1.3
thermonuclease family protein
compare
MMJJ
_RS07010
+0.2
1.6
preprotein translocase subunit Sec61beta
compare
MMJJ
_RS05520
+0.2
1.9
H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein
compare
MMJJ
_RS06450
+0.2
1.9
DUF3343 domain-containing protein
compare
MMJJ
_RS08380
+0.2
0.6
hypothetical protein
compare
MMJJ
_RS04780
+0.2
0.9
nucleic acid-binding protein
compare
MMJJ
_RS05500
+0.2
2.1
hypothetical protein
compare
MMJJ
_RS00420
+0.2
1.4
CBS domain-containing protein
compare
MMJJ
_RS06585
+0.2
1.6
alanine racemase
compare
MMJJ
_RS01095
+0.2
1.6
site-specific integrase
compare
MMJJ
_RS07200
+0.2
1.7
MFS transporter
compare
MMJJ
_RS08315
+0.2
1.7
DNA protection protein DPS
compare
MMJJ
_RS08745
+0.2
1.8
glycosyltransferase family 9 protein
compare
MMJJ
_RS06745
+0.2
1.3
energy-coupling factor ABC transporter permease
compare
MMJJ
_RS00740
+0.2
1.4
hypothetical protein
compare
MMJJ
_RS03595
+0.2
1.3
hypothetical protein
compare
MMJJ
_RS08410
+0.2
0.7
CBS domain-containing protein
compare
MMJJ
_RS06135
+0.2
1.7
50S ribosomal protein L11 methyltransferase
compare
MMJJ
_RS05700
+0.2
1.5
metallophosphoesterase
compare
MMJJ
_RS04580
+0.2
1.7
2-phosphosulfolactate phosphatase
compare
MMJJ
_RS08285
+0.2
1.6
class I SAM-dependent methyltransferase
compare
MMJJ
_RS00745
+0.2
0.7
hypothetical protein
compare
MMJJ
_RS09360
+0.2
1.5
hypothetical protein
compare
MMJJ
_RS06770
+0.2
1.7
hypothetical protein
compare
MMJJ
_RS07820
+0.2
1.6
bifunctional hexulose-6-phosphate synthase/ribonuclease regulator
compare
MMJJ
_RS03040
+0.2
1.5
lactate utilization protein
compare
MMJJ
_RS08015
+0.2
1.1
HAD family hydrolase
compare
MMJJ
_RS04585
+0.2
1.5
phenylacetate--CoA ligase
compare
MMJJ
_RS05715
+0.2
1.6
phosphoadenosine phosphosulfate reductase family protein
compare
MMJJ
_RS00170
+0.2
1.0
thioredoxin family protein
compare
MMJJ
_RS06520
+0.2
1.5
TldD/PmbA family protein
compare
MMJJ
_RS05200
+0.2
1.6
TIGR04013 family B12-binding domain/radical SAM domain-containing protein
compare
MMJJ
_RS07280
+0.2
1.3
phosphomannomutase/phosphoglucomutase
compare
MMJJ
_RS05990
+0.2
1.3
phosphatase PAP2 family protein
compare
MMJJ
_RS07255
+0.2
1.7
hypothetical protein
compare
MMJJ
_RS06430
+0.2
1.1
haloacid dehalogenase
compare
MMJJ
_RS05355
+0.2
1.3
DUF2121 domain-containing protein
compare
MMJJ
_RS04510
+0.2
1.5
hypothetical protein
compare
MMJJ
_RS04420
+0.2
1.6
type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family
compare
MMJJ
_RS06280
+0.2
1.4
hypothetical protein
compare
MMJJ
_RS07695
+0.2
1.6
glycoside hydrolase family 15 protein
compare
MMJJ
_RS08485
+0.2
0.8
Lrp/AsnC family transcriptional regulator
compare
MMJJ
_RS03605
+0.2
0.8
TIGR00297 family protein
compare
MMJJ
_RS05585
+0.2
1.3
hypothetical protein
compare
MMJJ
_RS07680
+0.2
1.2
glucose-6-phosphate isomerase
compare
MMJJ
_RS06045
+0.2
1.1
hypothetical protein
compare
MMJJ
_RS02880
+0.2
1.2
hypothetical protein
compare
MMJJ
_RS01955
+0.2
1.5
hypothetical protein
compare
MMJJ
_RS05965
+0.2
1.5
MFS transporter
compare
MMJJ
_RS05350
+0.2
0.8
DUF192 domain-containing protein
compare
MMJJ
_RS08365
+0.2
1.0
DsrE family protein
compare
MMJJ
_RS06555
+0.2
1.4
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS00900
+0.2
0.6
PC4/YdbC family ssDNA-binding protein
compare
MMJJ
_RS06100
+0.2
1.1
rubrerythrin
compare
MMJJ
_RS04830
+0.2
0.9
zinc dependent phospholipase C family protein
compare
MMJJ
_RS03795
+0.2
1.3
PQQ-binding-like beta-propeller repeat protein
compare
MMJJ
_RS05235
+0.2
1.5
Flp pilus assembly complex ATPase component TadA
compare
MMJJ
_RS09145
+0.2
1.1
exodeoxyribonuclease III
compare
MMJJ
_RS05835
+0.2
1.4
bis-aminopropyl spermidine synthase family protein
compare
MMJJ
_RS05385
+0.2
1.2
hypothetical protein
compare
MMJJ
_RS05405
+0.2
1.3
DNA cytosine methyltransferase
compare
MMJJ
_RS06455
+0.2
1.3
YeeE/YedE family protein
compare
MMJJ
_RS01845
+0.2
1.2
acetolactate decarboxylase
compare
MMJJ
_RS08350
+0.2
1.4
heavy metal translocating P-type ATPase
compare
MMJJ
_RS04745
+0.2
0.8
cyclase family protein
compare
MMJJ
_RS03320
+0.2
0.6
hypothetical protein
compare
MMJJ
_RS05665
+0.2
1.2
hypothetical protein
compare
MMJJ
_RS01310
+0.2
1.2
phenylacetate--CoA ligase
compare
MMJJ
_RS08705
+0.2
1.0
AEC family transporter
compare
MMJJ
_RS07480
+0.2
1.3
FAD-dependent oxidoreductase
compare
MMJJ
_RS05245
+0.2
1.1
type II secretion system F family protein
compare
MMJJ
_RS01510
+0.2
1.2
ATP-binding protein
compare
MMJJ
_RS01950
+0.2
1.1
hypothetical protein
compare
MMJJ
_RS06285
+0.2
1.0
YchF/TatD family DNA exonuclease
compare
MMJJ
_RS08025
+0.2
0.7
hypothetical protein
compare
MMJJ
_RS07835
+0.2
1.1
UPF0489 family protein
compare
MMJJ
_RS03045
+0.2
1.1
hypothetical protein
compare
MMJJ
_RS06130
+0.2
0.9
hypothetical protein
compare
MMJJ
_RS07885
+0.2
1.1
NERD domain-containing protein
compare
MMJJ
_RS00150
+0.2
0.9
DUF2180 family protein
compare
MMJJ
_RS02170
+0.2
0.9
2-thiouracil desulfurase family protein
compare
MMJJ
_RS04825
+0.2
1.2
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
compare
MMJJ
_RS01795
+0.2
1.0
TIGR00266 family protein
compare
MMJJ
_RS08735
+0.1
1.3
hypothetical protein
compare
MMJJ
_RS07005
+0.1
0.7
transcription factor S
compare
MMJJ
_RS00090
+0.1
1.1
4Fe-4S binding protein
compare
MMJJ
_RS06590
+0.1
1.1
sodium:alanine symporter family protein
compare
MMJJ
_RS06495
+0.1
0.5
hypothetical protein
compare
MMJJ
_RS08395
+0.1
1.2
CoB--CoM heterodisulfide reductase subunit B
compare
MMJJ
_RS00320
+0.1
0.7
chemotaxis protein CheD
compare
MMJJ
_RS06080
+0.1
1.1
serine/threonine protein kinase
compare
MMJJ
_RS02160
+0.1
1.0
amino acid ABC transporter permease
compare
MMJJ
_RS08455
+0.1
0.8
tetratricopeptide repeat protein
compare
MMJJ
_RS05980
+0.1
0.9
DUF5400 domain-containing protein
compare
MMJJ
_RS05690
+0.1
1.3
hypothetical protein
compare
MMJJ
_RS01270
+0.1
0.9
4Fe-4S binding protein
compare
MMJJ
_RS00500
+0.1
0.6
GNAT family N-acetyltransferase
compare
MMJJ
_RS08275
+0.1
1.3
iron ABC transporter substrate-binding protein
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments