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Experiment set3IT057 for
Methanococcus maripaludis JJ
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formate McAA B12 dropout
200 most important genes:
gene
name
fitness
t score
description
MMJJ
_RS00235
-6.4
-24.1
hypothetical protein
compare
MMJJ
_RS00580
-6.0
-2.8
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG
compare
MMJJ
_RS05450
-5.5
-21.4
TIGR03576 family pyridoxal phosphate-dependent enzyme
compare
MMJJ
_RS02920
-5.3
-2.9
30S ribosomal protein S27ae
compare
MMJJ
_RS02045
-5.2
-4.5
molybdenum cofactor guanylyltransferase
compare
MMJJ
_RS03895
-5.1
-4.9
hydrogenase expression/formation protein HypE
compare
MMJJ
_RS05935
-4.6
-3.7
Era-like GTP-binding protein
compare
MMJJ
_RS07665
-4.6
-24.0
formate dehydrogenase subunit alpha
compare
MMJJ
_RS03840
-4.5
-3.1
DHH family phosphoesterase
compare
MMJJ
_RS05930
-4.5
-2.7
cell division protein SepF
compare
MMJJ
_RS08250
-4.5
-8.5
hydrogenase maturation peptidase HycI
compare
MMJJ
_RS01870
-4.4
-2.7
methanogenesis marker 15 protein
compare
MMJJ
_RS07950
-4.4
-4.2
4Fe-4S binding protein
compare
MMJJ
_RS07670
-4.3
-18.0
Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain
compare
MMJJ
_RS01750
-4.2
-3.8
ferrous iron transport protein A
compare
MMJJ
_RS05950
-4.2
-4.1
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
compare
MMJJ
_RS05575
-4.2
-6.1
2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase
compare
MMJJ
_RS06875
-4.1
-3.5
hypothetical protein
compare
MMJJ
_RS00275
-4.1
-3.1
coenzyme F420-0:L-glutamate ligase
compare
MMJJ
_RS06860
-4.1
-4.0
hypothetical protein
compare
MMJJ
_RS06840
-4.1
-3.9
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS00370
-4.1
-2.2
asparagine synthase (glutamine-hydrolyzing)
compare
MMJJ
_RS06725
-4.0
-16.6
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMJJ
_RS08330
-4.0
-4.7
SufD family Fe-S cluster assembly protein
compare
MMJJ
_RS02090
-4.0
-7.2
tyramine--L-glutamate ligase
compare
MMJJ
_RS03620
-3.9
-7.1
DUF2097 domain-containing protein
compare
MMJJ
_RS06695
-3.9
-4.3
amidohydrolase
compare
MMJJ
_RS08320
-3.9
-3.4
CDP-diacylglycerol--serine O-phosphatidyltransferase
compare
MMJJ
_RS04200
-3.9
-8.7
triphosphoribosyl-dephospho-CoA synthase
compare
MMJJ
_RS06180
-3.9
-3.7
tryptophan--tRNA ligase
compare
MMJJ
_RS06490
-3.9
-4.5
methanogenesis marker 2 protein
compare
MMJJ
_RS05535
-3.8
-14.2
hypothetical protein
compare
MMJJ
_RS03820
-3.8
-5.8
hydrogenase formation protein HypD
compare
MMJJ
_RS06255
-3.8
-8.4
tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3
compare
MMJJ
_RS07655
-3.8
-15.6
hypothetical protein
compare
MMJJ
_RS07945
-3.8
-4.1
4Fe-4S binding protein
compare
MMJJ
_RS03065
-3.7
-12.7
CBS domain-containing protein
compare
MMJJ
_RS07000
-3.7
-2.5
TrkH family potassium uptake protein
compare
MMJJ
_RS03615
-3.7
-4.2
cobalt-precorrin-8 methylmutase
compare
MMJJ
_RS06240
-3.7
-4.1
dihydropteroate synthase-like protein
compare
MMJJ
_RS03125
-3.7
-6.0
GMC oxidoreductase
compare
MMJJ
_RS08000
-3.7
-10.5
HesA/MoeB/ThiF family protein
compare
MMJJ
_RS08020
-3.7
-8.2
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS08625
-3.6
-8.1
magnesium/cobalt transporter CorA
compare
MMJJ
_RS00450
-3.6
-2.6
DUF126 domain-containing protein
compare
MMJJ
_RS01810
-3.6
-2.5
methyl coenzyme M reductase system, component A2
compare
MMJJ
_RS05070
-3.6
-3.0
DNA primase catalytic subunit PriS
compare
MMJJ
_RS01935
-3.6
-5.7
O-phosphoseryl-tRNA(Sec) selenium transferase
compare
MMJJ
_RS05620
-3.6
-5.4
CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein
compare
MMJJ
_RS07660
-3.5
-9.3
carbonic anhydrase
compare
MMJJ
_RS03580
-3.5
-5.1
TIGR00303 family protein
compare
MMJJ
_RS01415
-3.5
-4.2
beta-CASP ribonuclease aCPSF1
compare
MMJJ
_RS05650
-3.5
-4.4
formylmethanofuran dehydrogenase subunit B
compare
MMJJ
_RS06750
-3.5
-3.4
homoaconitase large subunit
compare
MMJJ
_RS03875
-3.5
-5.4
CBS domain-containing protein
compare
MMJJ
_RS01755
-3.4
-3.3
ferrous iron transport protein B
compare
MMJJ
_RS08005
-3.4
-18.0
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMJJ
_RS08795
-3.4
-3.6
phosphoglucosamine mutase
compare
MMJJ
_RS06040
-3.4
-5.1
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS00125
-3.4
-3.3
KEOPS complex subunit Cgi121
compare
MMJJ
_RS04155
-3.4
-9.5
hypothetical protein
compare
MMJJ
_RS03815
-3.4
-2.8
nascent polypeptide-associated complex protein
compare
MMJJ
_RS03660
-3.3
-5.5
DUF447 family protein
compare
MMJJ
_RS03670
-3.3
-5.7
precorrin-2 C(20)-methyltransferase
compare
MMJJ
_RS03800
-3.3
-11.7
aldolase
compare
MMJJ
_RS07190
-3.3
-5.4
RtcB family protein
compare
MMJJ
_RS06855
-3.3
-2.6
DUF2104 domain-containing protein
compare
MMJJ
_RS05655
-3.3
-7.9
HisA/HisF family protein
compare
MMJJ
_RS09375
-3.3
-2.5
hypothetical protein
compare
MMJJ
_RS08080
-3.2
-12.4
TIGR00300 family protein
compare
MMJJ
_RS04685
-3.2
-11.1
carbamoyltransferase HypF
compare
MMJJ
_RS08660
-3.2
-4.3
acetylornithine transaminase
compare
MMJJ
_RS04995
-3.2
-8.0
Tfx family DNA-binding protein
compare
MMJJ
_RS05770
-3.2
-2.9
flagellar protein D
compare
MMJJ
_RS04800
-3.1
-8.2
2-phospho-L-lactate guanylyltransferase
compare
MMJJ
_RS01815
-3.1
-5.2
DUF134 domain-containing protein
compare
MMJJ
_RS06915
-3.1
-13.2
helix-turn-helix domain-containing protein
compare
MMJJ
_RS05260
-3.1
-6.3
ATP-grasp domain-containing protein
compare
MMJJ
_RS03230
-3.1
-3.9
NAD(P)/FAD-dependent oxidoreductase
compare
MMJJ
_RS08340
-3.1
-5.9
archaeoflavoprotein AfpA
compare
MMJJ
_RS08065
-3.0
-3.0
precorrin-6Y C5,15-methyltransferase (decarboxylating) subunit CbiT
compare
MMJJ
_RS03295
-3.0
-15.7
PHP domain-containing protein
compare
MMJJ
_RS05490
-3.0
-3.6
imidazole glycerol phosphate synthase subunit HisF
compare
MMJJ
_RS05810
-3.0
-8.5
precorrin-4 C(11)-methyltransferase
compare
MMJJ
_RS03095
-3.0
-3.8
bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase
compare
MMJJ
_RS03785
-3.0
-3.6
hypothetical protein
compare
MMJJ
_RS06910
-3.0
-4.3
energy-converting NiFe hydrogenase A subunit EhaA
compare
MMJJ
_RS07720
-3.0
-1.9
UPF0058 family protein
compare
MMJJ
_RS07635
-3.0
-13.8
response regulator transcription factor
compare
MMJJ
_RS03150
-3.0
-8.3
2-phospho-L-lactate transferase
compare
MMJJ
_RS03110
-2.9
-5.5
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase
compare
MMJJ
_RS03830
-2.9
-12.0
CBS domain-containing protein
compare
MMJJ
_RS04655
-2.9
-7.1
FAD-dependent oxidoreductase
compare
MMJJ
_RS05590
-2.9
-2.5
homoserine dehydrogenase
compare
MMJJ
_RS00475
-2.8
-2.9
bifunctional ornithine acetyltransferase/N-acetylglutamate synthase
compare
MMJJ
_RS05610
-2.8
-5.9
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMJJ
_RS03200
-2.8
-2.7
uroporphyrinogen-III synthase
compare
MMJJ
_RS08055
-2.8
-6.2
methanogenesis marker 14 protein
compare
MMJJ
_RS04050
-2.8
-2.5
dihydroneopterin aldolase family protein
compare
MMJJ
_RS07650
-2.7
-18.1
formate/nitrite transporter family protein
compare
MMJJ
_RS03270
-2.7
-2.6
ribosome biogenesis/translation initiation ATPase RLI
compare
MMJJ
_RS06785
-2.7
-7.7
RNA ligase partner protein
compare
MMJJ
_RS07995
-2.7
-6.3
molybdenum cofactor biosynthesis protein MoaE
compare
MMJJ
_RS00570
-2.6
-2.6
ribonuclease P
compare
MMJJ
_RS01565
-2.6
-7.7
TIGR00267 family protein
compare
MMJJ
_RS07380
-2.6
-9.6
sulfide-dependent adenosine diphosphate thiazole synthase
compare
MMJJ
_RS08095
-2.6
-5.9
cobyric acid synthase CobQ
compare
MMJJ
_RS07410
-2.6
-4.4
methanogenesis marker protein Mmp4/MtxX
compare
MMJJ
_RS07640
-2.6
-18.3
cache domain-containing protein
compare
MMJJ
_RS08535
-2.6
-3.5
NOL1/NOP2/sun family putative RNA methylase
compare
MMJJ
_RS01355
-2.6
-4.4
UDP-N-acetyl-D-mannosamine dehydrogenase
compare
MMJJ
_RS03060
-2.6
-2.6
methanogenesis marker 7 protein
compare
MMJJ
_RS02275
-2.6
-2.9
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS08480
-2.6
-9.0
hydroxyethylthiazole kinase
compare
MMJJ
_RS07705
-2.6
-3.5
GTP-binding protein EngB
compare
MMJJ
_RS03630
-2.5
-12.2
AMP phosphorylase
compare
MMJJ
_RS05190
-2.5
-7.8
gamma carbonic anhydrase family protein
compare
MMJJ
_RS07350
-2.5
-4.9
4Fe-4S binding protein
compare
MMJJ
_RS01865
-2.5
-8.3
peptidyl-tRNA hydrolase Pth2
compare
MMJJ
_RS02935
-2.5
-3.6
DNA-directed RNA polymerase subunit E''
compare
MMJJ
_RS04485
-2.5
-9.2
riboflavin synthase
compare
MMJJ
_RS04980
-2.5
-4.5
bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase
compare
MMJJ
_RS01600
-2.5
-3.4
radical SAM protein
compare
MMJJ
_RS09130
-2.4
-2.2
NFYB/HAP3 family transcription factor subunit
compare
MMJJ
_RS06375
-2.4
-5.0
UbiX family flavin prenyltransferase
compare
MMJJ
_RS04730
-2.4
-3.9
tyrosine decarboxylase MfnA
compare
MMJJ
_RS01360
-2.4
-2.7
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMJJ
_RS04675
-2.4
-5.9
thiamine pyrophosphate-binding protein
compare
MMJJ
_RS03810
-2.4
-3.3
AIR synthase-related protein
compare
MMJJ
_RS01345
-2.4
-4.1
(5-formylfuran-3-yl)methyl phosphate synthase
compare
MMJJ
_RS04615
-2.4
-4.8
methanogenesis marker 3 protein
compare
MMJJ
_RS03190
-2.4
-2.9
phosphopyruvate hydratase
compare
MMJJ
_RS06220
-2.3
-5.6
polyamine aminopropyltransferase
compare
MMJJ
_RS04790
-2.3
-4.2
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMJJ
_RS00210
-2.3
-2.7
DUF530 family protein
compare
MMJJ
_RS01820
-2.3
-7.0
MJ1244 family protein
compare
MMJJ
_RS06250
-2.3
-3.1
nicotinamide-nucleotide adenylyltransferase
compare
MMJJ
_RS04520
-2.3
-5.4
coenzyme F430 synthase
compare
MMJJ
_RS07785
-2.3
-3.6
fumarate reductase subunit A
compare
MMJJ
_RS06510
-2.3
-3.3
LL-diaminopimelate aminotransferase
compare
MMJJ
_RS06050
-2.3
-12.1
molybdopterin molybdotransferase MoeA
compare
MMJJ
_RS01475
-2.3
-2.4
signal recognition particle-docking protein FtsY
compare
MMJJ
_RS03115
-2.2
-5.4
sulfopyruvate decarboxylase subunit alpha
compare
MMJJ
_RS06485
-2.2
-3.5
phosphoglycerate kinase
compare
MMJJ
_RS07725
-2.2
-7.3
DNA primase DnaG
compare
MMJJ
_RS07155
-2.2
-7.7
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMJJ
_RS07345
-2.2
-5.8
homocysteine biosynthesis protein
compare
MMJJ
_RS04985
-2.2
-4.7
glutamyl-tRNA reductase
compare
MMJJ
_RS04670
-2.2
-4.8
DUF2117 domain-containing protein
compare
MMJJ
_RS07430
-2.2
-4.3
ribonuclease VapC
compare
MMJJ
_RS06625
-2.1
-2.0
pyruvate synthase subunit PorB
compare
MMJJ
_RS06185
-2.1
-4.9
cobalamin biosynthesis protein
compare
MMJJ
_RS07355
-2.1
-5.9
MoaD/ThiS family protein
compare
MMJJ
_RS05445
-2.1
-2.3
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
MMJJ
_RS01200
-2.1
-3.1
PRC-barrel domain-containing protein
compare
MMJJ
_RS05995
-2.1
-2.5
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS00270
-2.1
-3.7
adenosylcobinamide-GDP ribazoletransferase
compare
MMJJ
_RS06835
-2.1
-9.1
4Fe-4S binding protein
compare
MMJJ
_RS06225
-2.1
-2.5
adenosylmethionine decarboxylase
compare
MMJJ
_RS00600
-2.1
-3.3
hydroxymethylbilane synthase
compare
MMJJ
_RS04010
-2.1
-5.9
archaeal proteasome endopeptidase complex subunit alpha
compare
MMJJ
_RS08155
-2.1
-3.4
cobalt-precorrin-5B (C(1))-methyltransferase CbiD
compare
MMJJ
_RS08430
-2.1
-6.6
small nuclear ribonucleoprotein
compare
MMJJ
_RS01880
-2.1
-2.5
RlmE family RNA methyltransferase
compare
MMJJ
_RS08855
-2.1
-4.4
cyclic pyranopterin monophosphate synthase MoaC
compare
MMJJ
_RS04475
-2.1
-5.6
3,4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMJJ
_RS05540
-2.1
-14.5
LysR family transcriptional regulator
compare
MMJJ
_RS05375
-2.0
-13.4
radical SAM protein
compare
MMJJ
_RS08335
-2.0
-2.0
ABC transporter ATP-binding protein
compare
MMJJ
_RS06175
-2.0
-3.0
DUF1743 domain-containing protein
compare
MMJJ
_RS03005
-2.0
-3.6
Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit
compare
MMJJ
_RS04565
-2.0
-2.3
sirohydrochlorin nickelochelatase
compare
MMJJ
_RS07275
-2.0
-3.4
formate--phosphoribosylaminoimidazolecarboxamide ligase
compare
MMJJ
_RS02055
-2.0
-11.1
GTP 3',8-cyclase MoaA
compare
MMJJ
_RS06705
-2.0
-4.4
bifunctional NADP phosphatase/NAD kinase
compare
MMJJ
_RS05330
-2.0
-2.7
DNA polymerase II large subunit
compare
MMJJ
_RS03055
-1.9
-3.7
hypothetical protein
compare
MMJJ
_RS00560
-1.9
-3.5
homoisocitrate dehydrogenase
compare
MMJJ
_RS08840
-1.9
-4.0
calcium/sodium antiporter
compare
MMJJ
_RS01690
-1.9
-3.5
methanogenesis marker 12 protein
compare
MMJJ
_RS05295
-1.9
-8.8
cobyrinic acid a,c-diamide synthase
compare
MMJJ
_RS06170
-1.9
-8.9
hypothetical protein
compare
MMJJ
_RS04620
-1.9
-2.5
homocitrate synthase family protein
compare
MMJJ
_RS05765
-1.9
-1.4
flagellar protein E
compare
MMJJ
_RS04595
-1.9
-5.0
hypothetical protein
compare
MMJJ
_RS03845
-1.9
-3.4
translation initiation factor IF-2
compare
MMJJ
_RS05415
-1.9
-2.1
hypothetical protein
compare
MMJJ
_RS02200
-1.9
-6.1
chorismate pyruvate-lyase family protein
compare
MMJJ
_RS00355
-1.8
-2.8
ribonuclease P protein component 4
compare
MMJJ
_RS07960
-1.8
-2.1
quinolinate synthase NadA
compare
MMJJ
_RS09175
-1.8
-1.8
anthranilate synthase component I
compare
MMJJ
_RS06010
-1.8
-6.4
hypothetical protein
compare
MMJJ
_RS08585
-1.8
-5.8
M42 family metallopeptidase
compare
MMJJ
_RS09190
-1.8
-2.3
tryptophan synthase subunit beta
compare
MMJJ
_RS07840
-1.8
-2.0
Glu-tRNA(Gln) amidotransferase subunit GatD
compare
MMJJ
_RS01410
-1.8
-4.8
archaeal proteasome endopeptidase complex subunit beta
compare
MMJJ
_RS07370
-1.8
-3.5
tRNA 4-thiouridine(8) synthase ThiI
compare
MMJJ
_RS00215
-1.8
-2.7
CCA tRNA nucleotidyltransferase
compare
MMJJ
_RS08190
-1.8
-2.8
hypothetical protein
compare
MMJJ
_RS00550
-1.8
-8.1
AIR synthase-related protein
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments