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Experiment set3IT056 for
Methanococcus maripaludis JJ
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formate McAA B12 dropout
200 most important genes:
gene
name
fitness
t score
description
MMJJ
_RS00235
-6.1
-19.7
hypothetical protein
compare
MMJJ
_RS00570
-5.9
-2.6
ribonuclease P
compare
MMJJ
_RS00275
-5.4
-3.0
coenzyme F420-0:L-glutamate ligase
compare
MMJJ
_RS02045
-5.3
-4.3
molybdenum cofactor guanylyltransferase
compare
MMJJ
_RS06860
-5.1
-6.1
hypothetical protein
compare
MMJJ
_RS04200
-5.0
-8.9
triphosphoribosyl-dephospho-CoA synthase
compare
MMJJ
_RS06695
-4.8
-4.2
amidohydrolase
compare
MMJJ
_RS05450
-4.8
-17.5
TIGR03576 family pyridoxal phosphate-dependent enzyme
compare
MMJJ
_RS03615
-4.8
-4.3
cobalt-precorrin-8 methylmutase
compare
MMJJ
_RS03895
-4.6
-5.2
hydrogenase expression/formation protein HypE
compare
MMJJ
_RS00425
-4.6
-5.1
hypothetical protein
compare
MMJJ
_RS06855
-4.5
-1.9
DUF2104 domain-containing protein
compare
MMJJ
_RS04050
-4.5
-2.7
dihydroneopterin aldolase family protein
compare
MMJJ
_RS03110
-4.5
-5.3
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase
compare
MMJJ
_RS06625
-4.5
-3.0
pyruvate synthase subunit PorB
compare
MMJJ
_RS07665
-4.4
-24.4
formate dehydrogenase subunit alpha
compare
MMJJ
_RS05650
-4.4
-4.2
formylmethanofuran dehydrogenase subunit B
compare
MMJJ
_RS02090
-4.4
-7.7
tyramine--L-glutamate ligase
compare
MMJJ
_RS06490
-4.3
-4.0
methanogenesis marker 2 protein
compare
MMJJ
_RS07670
-4.3
-19.3
Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain
compare
MMJJ
_RS03840
-4.3
-4.1
DHH family phosphoesterase
compare
MMJJ
_RS03580
-4.2
-5.0
TIGR00303 family protein
compare
MMJJ
_RS01810
-4.2
-2.7
methyl coenzyme M reductase system, component A2
compare
MMJJ
_RS05070
-4.2
-3.2
DNA primase catalytic subunit PriS
compare
MMJJ
_RS05065
-4.1
-5.4
(4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase
compare
MMJJ
_RS01935
-4.0
-6.1
O-phosphoseryl-tRNA(Sec) selenium transferase
compare
MMJJ
_RS05225
-3.9
-1.3
Gar1/Naf1 family protein
compare
MMJJ
_RS01755
-3.9
-2.6
ferrous iron transport protein B
compare
MMJJ
_RS07655
-3.9
-14.4
hypothetical protein
compare
MMJJ
_RS01475
-3.9
-2.8
signal recognition particle-docking protein FtsY
compare
MMJJ
_RS05445
-3.8
-3.1
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
MMJJ
_RS06040
-3.8
-5.4
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS08330
-3.8
-4.7
SufD family Fe-S cluster assembly protein
compare
MMJJ
_RS08850
-3.8
-3.1
succinate dehydrogenase/fumarate reductase iron-sulfur subunit
compare
MMJJ
_RS07660
-3.8
-11.5
carbonic anhydrase
compare
MMJJ
_RS08020
-3.7
-9.3
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS03200
-3.7
-2.8
uroporphyrinogen-III synthase
compare
MMJJ
_RS08320
-3.7
-2.8
CDP-diacylglycerol--serine O-phosphatidyltransferase
compare
MMJJ
_RS00210
-3.7
-3.3
DUF530 family protein
compare
MMJJ
_RS03065
-3.6
-14.0
CBS domain-containing protein
compare
MMJJ
_RS04685
-3.6
-12.0
carbamoyltransferase HypF
compare
MMJJ
_RS05575
-3.6
-5.8
2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase
compare
MMJJ
_RS08625
-3.6
-8.8
magnesium/cobalt transporter CorA
compare
MMJJ
_RS03760
-3.6
-4.4
hydrogenase maturation nickel metallochaperone HypA
compare
MMJJ
_RS06875
-3.5
-3.6
hypothetical protein
compare
MMJJ
_RS02200
-3.5
-13.4
chorismate pyruvate-lyase family protein
compare
MMJJ
_RS05535
-3.5
-15.8
hypothetical protein
compare
MMJJ
_RS06725
-3.5
-13.4
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMJJ
_RS07410
-3.5
-5.1
methanogenesis marker protein Mmp4/MtxX
compare
MMJJ
_RS03875
-3.5
-5.2
CBS domain-containing protein
compare
MMJJ
_RS04995
-3.5
-7.9
Tfx family DNA-binding protein
compare
MMJJ
_RS06240
-3.4
-4.3
dihydropteroate synthase-like protein
compare
MMJJ
_RS01565
-3.4
-10.3
TIGR00267 family protein
compare
MMJJ
_RS00560
-3.4
-4.6
homoisocitrate dehydrogenase
compare
MMJJ
_RS04800
-3.4
-8.0
2-phospho-L-lactate guanylyltransferase
compare
MMJJ
_RS04485
-3.4
-9.2
riboflavin synthase
compare
MMJJ
_RS01880
-3.4
-4.2
RlmE family RNA methyltransferase
compare
MMJJ
_RS05490
-3.4
-3.8
imidazole glycerol phosphate synthase subunit HisF
compare
MMJJ
_RS07635
-3.3
-15.9
response regulator transcription factor
compare
MMJJ
_RS03865
-3.3
-2.0
phosphoribosyl-AMP cyclohydrolase
compare
MMJJ
_RS05260
-3.3
-7.9
ATP-grasp domain-containing protein
compare
MMJJ
_RS05930
-3.3
-3.0
cell division protein SepF
compare
MMJJ
_RS08155
-3.3
-5.7
cobalt-precorrin-5B (C(1))-methyltransferase CbiD
compare
MMJJ
_RS00215
-3.3
-3.3
CCA tRNA nucleotidyltransferase
compare
MMJJ
_RS08005
-3.3
-17.5
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMJJ
_RS07720
-3.2
-2.9
UPF0058 family protein
compare
MMJJ
_RS08250
-3.2
-6.9
hydrogenase maturation peptidase HycI
compare
MMJJ
_RS04155
-3.2
-8.0
hypothetical protein
compare
MMJJ
_RS05950
-3.2
-4.3
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
compare
MMJJ
_RS04730
-3.2
-3.8
tyrosine decarboxylase MfnA
compare
MMJJ
_RS06250
-3.2
-3.2
nicotinamide-nucleotide adenylyltransferase
compare
MMJJ
_RS00580
-3.2
-2.7
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG
compare
MMJJ
_RS05620
-3.2
-6.3
CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein
compare
MMJJ
_RS01600
-3.2
-2.9
radical SAM protein
compare
MMJJ
_RS01750
-3.2
-3.1
ferrous iron transport protein A
compare
MMJJ
_RS03800
-3.1
-10.2
aldolase
compare
MMJJ
_RS04615
-3.1
-5.2
methanogenesis marker 3 protein
compare
MMJJ
_RS03620
-3.1
-5.9
DUF2097 domain-containing protein
compare
MMJJ
_RS06915
-3.1
-11.8
helix-turn-helix domain-containing protein
compare
MMJJ
_RS02920
-3.1
-3.0
30S ribosomal protein S27ae
compare
MMJJ
_RS02935
-3.1
-4.1
DNA-directed RNA polymerase subunit E''
compare
MMJJ
_RS05655
-3.1
-9.4
HisA/HisF family protein
compare
MMJJ
_RS08000
-3.1
-8.8
HesA/MoeB/ThiF family protein
compare
MMJJ
_RS06375
-3.1
-5.5
UbiX family flavin prenyltransferase
compare
MMJJ
_RS04520
-3.0
-6.3
coenzyme F430 synthase
compare
MMJJ
_RS06110
-3.0
-3.0
bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC
compare
MMJJ
_RS05190
-3.0
-8.8
gamma carbonic anhydrase family protein
compare
MMJJ
_RS06930
-3.0
-3.8
type II methionyl aminopeptidase
compare
MMJJ
_RS02275
-3.0
-4.5
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS06510
-3.0
-3.7
LL-diaminopimelate aminotransferase
compare
MMJJ
_RS07000
-3.0
-2.2
TrkH family potassium uptake protein
compare
MMJJ
_RS03295
-2.9
-15.8
PHP domain-containing protein
compare
MMJJ
_RS07350
-2.9
-4.1
4Fe-4S binding protein
compare
MMJJ
_RS00450
-2.9
-2.0
DUF126 domain-containing protein
compare
MMJJ
_RS06255
-2.9
-9.3
tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3
compare
MMJJ
_RS03820
-2.9
-4.3
hydrogenase formation protein HypD
compare
MMJJ
_RS08080
-2.9
-10.1
TIGR00300 family protein
compare
MMJJ
_RS01865
-2.9
-7.3
peptidyl-tRNA hydrolase Pth2
compare
MMJJ
_RS07470
-2.9
-2.6
50S ribosome-binding GTPase
compare
MMJJ
_RS06220
-2.8
-7.5
polyamine aminopropyltransferase
compare
MMJJ
_RS07640
-2.8
-20.3
cache domain-containing protein
compare
MMJJ
_RS03830
-2.8
-11.1
CBS domain-containing protein
compare
MMJJ
_RS06180
-2.8
-3.7
tryptophan--tRNA ligase
compare
MMJJ
_RS03150
-2.8
-8.2
2-phospho-L-lactate transferase
compare
MMJJ
_RS06805
-2.8
-3.3
monovalent cation/H+ antiporter subunit E
compare
MMJJ
_RS03230
-2.8
-4.9
NAD(P)/FAD-dependent oxidoreductase
compare
MMJJ
_RS06185
-2.7
-6.0
cobalamin biosynthesis protein
compare
MMJJ
_RS01815
-2.7
-5.3
DUF134 domain-containing protein
compare
MMJJ
_RS00195
-2.7
-4.1
precorrin-3B C(17)-methyltransferase
compare
MMJJ
_RS07650
-2.7
-18.7
formate/nitrite transporter family protein
compare
MMJJ
_RS06910
-2.7
-2.5
energy-converting NiFe hydrogenase A subunit EhaA
compare
MMJJ
_RS06050
-2.7
-10.6
molybdopterin molybdotransferase MoeA
compare
MMJJ
_RS03005
-2.7
-5.2
Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit
compare
MMJJ
_RS04790
-2.7
-5.3
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMJJ
_RS05995
-2.7
-2.4
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS06840
-2.7
-4.2
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS04675
-2.6
-5.6
thiamine pyrophosphate-binding protein
compare
MMJJ
_RS08795
-2.6
-3.2
phosphoglucosamine mutase
compare
MMJJ
_RS08340
-2.6
-4.7
archaeoflavoprotein AfpA
compare
MMJJ
_RS03225
-2.6
-3.4
4Fe-4S binding protein
compare
MMJJ
_RS00265
-2.6
-7.8
TIGR02253 family HAD-type hydrolase
compare
MMJJ
_RS05590
-2.6
-2.3
homoserine dehydrogenase
compare
MMJJ
_RS00600
-2.6
-3.4
hydroxymethylbilane synthase
compare
MMJJ
_RS03670
-2.6
-4.7
precorrin-2 C(20)-methyltransferase
compare
MMJJ
_RS07380
-2.6
-10.8
sulfide-dependent adenosine diphosphate thiazole synthase
compare
MMJJ
_RS08585
-2.5
-8.8
M42 family metallopeptidase
compare
MMJJ
_RS08480
-2.5
-9.3
hydroxyethylthiazole kinase
compare
MMJJ
_RS01820
-2.5
-5.3
MJ1244 family protein
compare
MMJJ
_RS01690
-2.5
-3.4
methanogenesis marker 12 protein
compare
MMJJ
_RS06785
-2.5
-7.6
RNA ligase partner protein
compare
MMJJ
_RS03965
-2.5
-2.2
DNA-directed RNA polymerase subunit L
compare
MMJJ
_RS01870
-2.5
-2.5
methanogenesis marker 15 protein
compare
MMJJ
_RS00125
-2.5
-2.7
KEOPS complex subunit Cgi121
compare
MMJJ
_RS08055
-2.4
-6.8
methanogenesis marker 14 protein
compare
MMJJ
_RS08095
-2.4
-5.0
cobyric acid synthase CobQ
compare
MMJJ
_RS03270
-2.4
-2.8
ribosome biogenesis/translation initiation ATPase RLI
compare
MMJJ
_RS08430
-2.4
-7.5
small nuclear ribonucleoprotein
compare
MMJJ
_RS01345
-2.4
-4.0
(5-formylfuran-3-yl)methyl phosphate synthase
compare
MMJJ
_RS04655
-2.4
-7.2
FAD-dependent oxidoreductase
compare
MMJJ
_RS03630
-2.4
-10.7
AMP phosphorylase
compare
MMJJ
_RS07945
-2.4
-2.4
4Fe-4S binding protein
compare
MMJJ
_RS06155
-2.4
-4.6
phosphatidylglycerophosphatase A
compare
MMJJ
_RS06010
-2.4
-6.3
hypothetical protein
compare
MMJJ
_RS03095
-2.3
-2.9
bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase
compare
MMJJ
_RS08855
-2.3
-5.5
cyclic pyranopterin monophosphate synthase MoaC
compare
MMJJ
_RS09190
-2.3
-2.3
tryptophan synthase subunit beta
compare
MMJJ
_RS06750
-2.3
-2.3
homoaconitase large subunit
compare
MMJJ
_RS01360
-2.3
-3.0
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMJJ
_RS04985
-2.3
-4.7
glutamyl-tRNA reductase
compare
MMJJ
_RS07345
-2.3
-6.3
homocysteine biosynthesis protein
compare
MMJJ
_RS08840
-2.3
-4.0
calcium/sodium antiporter
compare
MMJJ
_RS05155
-2.3
-5.8
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH
compare
MMJJ
_RS05295
-2.3
-9.8
cobyrinic acid a,c-diamide synthase
compare
MMJJ
_RS03845
-2.3
-3.6
translation initiation factor IF-2
compare
MMJJ
_RS06865
-2.2
-3.0
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS04670
-2.2
-5.2
DUF2117 domain-containing protein
compare
MMJJ
_RS02040
-2.2
-2.1
Asp-tRNA(Asn) amidotransferase subunit GatC
compare
MMJJ
_RS03055
-2.2
-3.4
hypothetical protein
compare
MMJJ
_RS00205
-2.2
-5.6
adenosylcobinamide-phosphate synthase CbiB
compare
MMJJ
_RS00550
-2.2
-9.4
AIR synthase-related protein
compare
MMJJ
_RS00355
-2.2
-3.5
ribonuclease P protein component 4
compare
MMJJ
_RS08660
-2.1
-3.3
acetylornithine transaminase
compare
MMJJ
_RS01200
-2.1
-3.3
PRC-barrel domain-containing protein
compare
MMJJ
_RS03125
-2.1
-3.2
GMC oxidoreductase
compare
MMJJ
_RS05810
-2.1
-5.7
precorrin-4 C(11)-methyltransferase
compare
MMJJ
_RS05330
-2.1
-2.5
DNA polymerase II large subunit
compare
MMJJ
_RS07995
-2.1
-6.1
molybdenum cofactor biosynthesis protein MoaE
compare
MMJJ
_RS03115
-2.1
-5.3
sulfopyruvate decarboxylase subunit alpha
compare
MMJJ
_RS08065
-2.1
-2.9
precorrin-6Y C5,15-methyltransferase (decarboxylating) subunit CbiT
compare
MMJJ
_RS06170
-2.1
-8.2
hypothetical protein
compare
MMJJ
_RS06835
-2.1
-8.8
4Fe-4S binding protein
compare
MMJJ
_RS05935
-2.1
-2.7
Era-like GTP-binding protein
compare
MMJJ
_RS04010
-2.1
-7.5
archaeal proteasome endopeptidase complex subunit alpha
compare
MMJJ
_RS07155
-2.1
-8.6
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMJJ
_RS07275
-2.0
-3.2
formate--phosphoribosylaminoimidazolecarboxamide ligase
compare
MMJJ
_RS05380
-2.0
-1.4
hypothetical protein
compare
MMJJ
_RS02190
-2.0
-11.1
molybdopterin biosynthesis protein
compare
MMJJ
_RS03060
-2.0
-2.4
methanogenesis marker 7 protein
compare
MMJJ
_RS07245
-2.0
-4.3
amidohydrolase family protein
compare
MMJJ
_RS06700
-2.0
-3.7
L-seryl-tRNA(Sec) kinase
compare
MMJJ
_RS07355
-2.0
-5.3
MoaD/ThiS family protein
compare
MMJJ
_RS06940
-2.0
-9.5
metalloregulator ArsR/SmtB family transcription factor
compare
MMJJ
_RS04980
-2.0
-4.2
bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase
compare
MMJJ
_RS08620
-2.0
-3.6
DUF373 family protein
compare
MMJJ
_RS00270
-2.0
-2.8
adenosylcobinamide-GDP ribazoletransferase
compare
MMJJ
_RS07950
-1.9
-2.8
4Fe-4S binding protein
compare
MMJJ
_RS05610
-1.9
-3.7
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMJJ
_RS01355
-1.9
-2.9
UDP-N-acetyl-D-mannosamine dehydrogenase
compare
MMJJ
_RS05540
-1.9
-12.5
LysR family transcriptional regulator
compare
MMJJ
_RS08170
-1.9
-2.4
diaminopimelate decarboxylase
compare
MMJJ
_RS07725
-1.9
-5.4
DNA primase DnaG
compare
MMJJ
_RS03140
-1.9
-9.7
tRNA-dihydrouridine synthase
compare
MMJJ
_RS04650
-1.9
-6.6
nitrogenase iron protein
compare
MMJJ
_RS04475
-1.9
-3.1
3,4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMJJ
_RS04565
-1.9
-2.2
sirohydrochlorin nickelochelatase
compare
MMJJ
_RS03765
-1.8
-5.9
hypothetical protein
compare
MMJJ
_RS06270
-1.8
-6.7
dethiobiotin synthase
compare
MMJJ
_RS08500
-1.8
-6.6
L-sulfolactate dehydrogenase
compare
MMJJ
_RS07980
-1.8
-9.5
biotin synthase BioB
compare
MMJJ
_RS03710
-1.8
-6.5
DUF2111 domain-containing protein
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments