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Experiment set3IT056 for
Methanococcus maripaludis JJ
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formate McAA B12 dropout
200 most detrimental genes:
gene
name
fitness
t score
description
MMJJ
_RS04415
+2.2
7.9
hypothetical protein
compare
MMJJ
_RS03725
+1.7
6.6
sulfurtransferase TusA family protein
compare
MMJJ
_RS07585
+0.9
5.3
DHH family phosphoesterase
compare
MMJJ
_RS04005
+0.9
6.4
acetate--CoA ligase family protein
compare
MMJJ
_RS08830
+0.9
3.0
hypothetical protein
compare
MMJJ
_RS07225
+0.8
5.1
coenzyme F420 hydrogenase subunit gamma
compare
MMJJ
_RS06540
+0.8
2.3
DUF2120 domain-containing protein
compare
MMJJ
_RS07235
+0.7
6.0
coenzyme F420 hydrogenase subunit alpha
compare
MMJJ
_RS03605
+0.7
2.7
TIGR00297 family protein
compare
MMJJ
_RS07185
+0.7
3.1
DUF371 domain-containing protein
compare
MMJJ
_RS03835
+0.7
2.8
DUF504 domain-containing protein
compare
MMJJ
_RS06210
+0.7
3.4
hypothetical protein
compare
MMJJ
_RS06275
+0.7
2.5
hypothetical protein
compare
MMJJ
_RS07025
+0.6
3.7
tRNA (cytidine(56)-2'-O)-methyltransferase
compare
MMJJ
_RS06800
+0.6
3.7
prefoldin subunit alpha
compare
MMJJ
_RS08935
+0.6
0.6
TIGR00288 family NYN domain-containing protein
compare
MMJJ
_RS06165
+0.6
4.0
archaeosine synthase subunit alpha
compare
MMJJ
_RS05685
+0.6
3.6
class III signal peptide-containing protein
compare
MMJJ
_RS08485
+0.6
2.6
Lrp/AsnC family transcriptional regulator
compare
MMJJ
_RS09405
+0.6
1.6
hypothetical protein
compare
MMJJ
_RS03250
+0.6
1.1
DUF2116 family Zn-ribbon domain-containing protein
compare
MMJJ
_RS07920
+0.6
3.6
6-carboxytetrahydropterin synthase QueD
compare
MMJJ
_RS07220
+0.5
4.0
coenzyme F420 hydrogenase subunit beta
compare
MMJJ
_RS01825
+0.5
2.4
DNA repair and recombination protein RadB
compare
MMJJ
_RS06470
+0.5
3.4
tripartite tricarboxylate transporter permease
compare
MMJJ
_RS07175
+0.5
3.9
DEAD/DEAH box helicase
compare
MMJJ
_RS07210
+0.5
3.7
AmmeMemoRadiSam system protein B
compare
MMJJ
_RS09360
+0.5
3.0
hypothetical protein
compare
MMJJ
_RS03515
+0.5
3.3
GPR1/FUN34/YaaH family transporter
compare
MMJJ
_RS01855
+0.5
3.3
MBL fold metallo-hydrolase
compare
MMJJ
_RS07765
+0.5
1.7
DMT family protein
compare
MMJJ
_RS07260
+0.5
2.8
PspC domain-containing protein
compare
MMJJ
_RS05040
+0.5
3.2
7-carboxy-7-deazaguanine synthase QueE
compare
MMJJ
_RS06770
+0.5
3.3
hypothetical protein
compare
MMJJ
_RS06535
+0.5
3.7
UPF0104 family protein
compare
MMJJ
_RS01035
+0.4
2.1
hypothetical protein
compare
MMJJ
_RS08490
+0.4
1.9
rubrerythrin family protein
compare
MMJJ
_RS06190
+0.4
3.1
7-cyano-7-deazaguanine synthase
compare
MMJJ
_RS06460
+0.4
2.6
cytochrome c
compare
MMJJ
_RS09205
+0.4
2.0
hypothetical protein
compare
MMJJ
_RS06735
+0.4
3.0
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS05975
+0.4
2.7
sulfurtransferase TusA family protein
compare
MMJJ
_RS06680
+0.4
2.1
DUF366 family protein
compare
MMJJ
_RS07230
+0.4
2.4
coenzyme F420-reducing hydrogenase, FrhD protein
compare
MMJJ
_RS08225
+0.4
1.6
peptidylprolyl isomerase
compare
MMJJ
_RS07985
+0.4
2.1
hypothetical protein
compare
MMJJ
_RS04350
+0.4
2.0
hypothetical protein
compare
MMJJ
_RS06500
+0.4
2.5
class I SAM-dependent methyltransferase
compare
MMJJ
_RS04215
+0.4
3.1
DMT family transporter
compare
MMJJ
_RS06810
+0.4
2.8
L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha
compare
MMJJ
_RS02180
+0.4
1.7
DHH family phosphoesterase
compare
MMJJ
_RS07795
+0.4
2.1
cupin domain-containing protein
compare
MMJJ
_RS05915
+0.4
1.4
multiprotein bridging factor aMBF1
compare
MMJJ
_RS04965
+0.4
1.0
RNA polymerase Rpb4 family protein
compare
MMJJ
_RS06710
+0.4
2.9
TldD/PmbA family protein
compare
MMJJ
_RS07445
+0.4
2.4
RlmF-related methyltransferase
compare
MMJJ
_RS06205
+0.4
2.3
EamA family transporter
compare
MMJJ
_RS08305
+0.4
1.8
peroxiredoxin
compare
MMJJ
_RS06745
+0.4
1.9
energy-coupling factor ABC transporter permease
compare
MMJJ
_RS06440
+0.4
2.3
DUF4870 domain-containing protein
compare
MMJJ
_RS09390
+0.4
0.9
hypothetical protein
compare
MMJJ
_RS03575
+0.4
1.8
NUDIX hydrolase
compare
MMJJ
_RS06120
+0.4
2.3
DUF4013 domain-containing protein
compare
MMJJ
_RS07450
+0.4
1.6
hypothetical protein
compare
MMJJ
_RS04955
+0.4
2.4
tRNA pseudouridine(54/55) synthase Pus10
compare
MMJJ
_RS07205
+0.3
1.8
MTH895/ArsE family thioredoxin-like protein
compare
MMJJ
_RS01670
+0.3
1.3
hypothetical protein
compare
MMJJ
_RS09295
+0.3
0.4
hypothetical protein
compare
MMJJ
_RS06685
+0.3
2.8
S-layer protein
compare
MMJJ
_RS08720
+0.3
2.4
UDP-glucose/GDP-mannose dehydrogenase family protein
compare
MMJJ
_RS04135
+0.3
1.3
7-cyano-7-deazaguanine synthase QueC
compare
MMJJ
_RS06640
+0.3
2.0
YfcE family phosphodiesterase
compare
MMJJ
_RS04105
+0.3
2.6
prepilin peptidase
compare
MMJJ
_RS06790
+0.3
2.5
nucleotidyltransferase family protein
compare
MMJJ
_RS07800
+0.3
2.4
AMP-binding protein
compare
MMJJ
_RS08100
+0.3
1.9
hypothetical protein
compare
MMJJ
_RS04830
+0.3
1.5
zinc dependent phospholipase C family protein
compare
MMJJ
_RS00440
+0.3
1.8
selenide, water dikinase SelD
compare
MMJJ
_RS05035
+0.3
1.4
4Fe-4S binding protein
compare
MMJJ
_RS07270
+0.3
1.8
ribonuclease HII
compare
MMJJ
_RS09065
+0.3
1.6
hypothetical protein
compare
MMJJ
_RS07620
+0.3
2.1
class I SAM-dependent rRNA methyltransferase
compare
MMJJ
_RS04270
+0.3
1.3
DUF364 domain-containing protein
compare
MMJJ
_RS05500
+0.3
2.6
hypothetical protein
compare
MMJJ
_RS07825
+0.3
1.2
YciI family protein
compare
MMJJ
_RS07680
+0.3
1.8
glucose-6-phosphate isomerase
compare
MMJJ
_RS06505
+0.3
0.9
prephenate dehydratase
compare
MMJJ
_RS06085
+0.3
1.0
proteasome assembly chaperone family protein
compare
MMJJ
_RS05885
+0.3
2.3
tungstate ABC transporter substrate-binding protein WtpA
compare
MMJJ
_RS00150
+0.3
1.6
DUF2180 family protein
compare
MMJJ
_RS06960
+0.3
2.4
CAP domain-containing protein
compare
MMJJ
_RS02185
+0.3
1.6
TIGR00296 family protein
compare
MMJJ
_RS02965
+0.3
1.3
RimK-like ATPgrasp N-terminal domain-containing protein
compare
MMJJ
_RS05510
+0.3
1.9
archaellum operon transcriptional activator EarA family protein
compare
MMJJ
_RS06520
+0.3
1.9
TldD/PmbA family protein
compare
MMJJ
_RS04815
+0.3
1.1
TIM barrel protein
compare
MMJJ
_RS06480
+0.3
1.7
hypothetical protein
compare
MMJJ
_RS08130
+0.3
0.2
translation initiation factor IF-2 subunit gamma
compare
MMJJ
_RS05580
+0.3
1.6
methanogenesis marker 9 domain-containing protein
compare
MMJJ
_RS04580
+0.3
2.0
2-phosphosulfolactate phosphatase
compare
MMJJ
_RS00585
+0.3
2.1
S-layer protein
compare
MMJJ
_RS01010
+0.3
2.5
right-handed parallel beta-helix repeat-containing protein
compare
MMJJ
_RS03850
+0.3
1.2
nucleoside-diphosphate kinase
compare
MMJJ
_RS05660
+0.3
1.5
sulfopyruvate decarboxylase subunit beta
compare
MMJJ
_RS03175
+0.3
1.6
zinc metalloprotease HtpX
compare
MMJJ
_RS05750
+0.3
1.8
flagellar accessory protein FlaH
compare
MMJJ
_RS05495
+0.3
1.8
MinD/ParA family protein
compare
MMJJ
_RS06515
+0.3
1.9
ribonuclease III
compare
MMJJ
_RS03595
+0.3
1.4
hypothetical protein
compare
MMJJ
_RS04825
+0.3
2.1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
compare
MMJJ
_RS05960
+0.3
1.5
DUF169 domain-containing protein
compare
MMJJ
_RS05200
+0.3
2.0
TIGR04013 family B12-binding domain/radical SAM domain-containing protein
compare
MMJJ
_RS04500
+0.3
1.5
hypothetical protein
compare
MMJJ
_RS01515
+0.3
1.0
DUF2178 domain-containing protein
compare
MMJJ
_RS07480
+0.3
1.9
FAD-dependent oxidoreductase
compare
MMJJ
_RS03610
+0.3
1.4
HIT family protein
compare
MMJJ
_RS05605
+0.3
0.9
hypothetical protein
compare
MMJJ
_RS06450
+0.3
1.8
DUF3343 domain-containing protein
compare
MMJJ
_RS07820
+0.2
1.8
bifunctional hexulose-6-phosphate synthase/ribonuclease regulator
compare
MMJJ
_RS03905
+0.2
1.0
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS06100
+0.2
1.5
rubrerythrin
compare
MMJJ
_RS00635
+0.2
1.6
ABC transporter permease subunit
compare
MMJJ
_RS04545
+0.2
0.7
PadR family transcriptional regulator
compare
MMJJ
_RS08525
+0.2
0.9
peptidylprolyl isomerase
compare
MMJJ
_RS05740
+0.2
1.9
archaellar assembly protein FlaJ
compare
MMJJ
_RS07255
+0.2
2.1
hypothetical protein
compare
MMJJ
_RS07590
+0.2
1.6
flap endonuclease-1
compare
MMJJ
_RS06455
+0.2
1.6
YeeE/YedE family protein
compare
MMJJ
_RS01140
+0.2
1.2
helix-turn-helix domain-containing protein
compare
MMJJ
_RS03410
+0.2
0.8
hypothetical protein
compare
MMJJ
_RS08735
+0.2
1.9
hypothetical protein
compare
MMJJ
_RS06675
+0.2
1.6
TIGR01212 family radical SAM protein
compare
MMJJ
_RS03375
+0.2
1.1
hypothetical protein
compare
MMJJ
_RS00845
+0.2
1.4
hypothetical protein
compare
MMJJ
_RS04245
+0.2
1.2
flavoprotein
compare
MMJJ
_RS01930
+0.2
1.0
Pre-mRNA processing ribonucleoprotein
compare
MMJJ
_RS07610
+0.2
1.2
DUF2119 domain-containing protein
compare
MMJJ
_RS07240
+0.2
1.9
MBL fold metallo-hydrolase
compare
MMJJ
_RS08285
+0.2
1.6
class I SAM-dependent methyltransferase
compare
MMJJ
_RS07200
+0.2
1.6
MFS transporter
compare
MMJJ
_RS06430
+0.2
1.1
haloacid dehalogenase
compare
MMJJ
_RS05690
+0.2
2.0
hypothetical protein
compare
MMJJ
_RS05940
+0.2
1.5
HAD family hydrolase
compare
MMJJ
_RS02230
+0.2
1.7
hypothetical protein
compare
MMJJ
_RS06135
+0.2
1.5
50S ribosomal protein L11 methyltransferase
compare
MMJJ
_RS05925
+0.2
1.2
DUF2099 family protein
compare
MMJJ
_RS05525
+0.2
1.1
GTP-binding protein
compare
MMJJ
_RS03525
+0.2
1.3
2-hydroxyacyl-CoA dehydratase family protein
compare
MMJJ
_RS06950
+0.2
1.3
4-demethylwyosine synthase TYW1
compare
MMJJ
_RS05795
+0.2
1.7
hypothetical protein
compare
MMJJ
_RS04850
+0.2
1.2
energy-coupling factor transporter transmembrane protein EcfT
compare
MMJJ
_RS00155
+0.2
1.6
DUF2193 domain-containing protein
compare
MMJJ
_RS00420
+0.2
1.1
CBS domain-containing protein
compare
MMJJ
_RS04585
+0.2
1.2
phenylacetate--CoA ligase
compare
MMJJ
_RS07810
+0.2
1.1
3-methyl-2-oxobutanoate dehydrogenase subunit VorB
compare
MMJJ
_RS03330
+0.2
1.2
hypothetical protein
compare
MMJJ
_RS04640
+0.2
1.5
TIGR01177 family methyltransferase
compare
MMJJ
_RS02340
+0.2
1.1
SAM-dependent methyltransferase
compare
MMJJ
_RS03015
+0.2
1.4
Ig-like domain-containing protein
compare
MMJJ
_RS01970
+0.2
0.8
hypothetical protein
compare
MMJJ
_RS05965
+0.2
1.5
MFS transporter
compare
MMJJ
_RS03510
+0.2
1.1
acyl-CoA dehydratase activase
compare
MMJJ
_RS06340
+0.2
0.4
coenzyme-B sulfoethylthiotransferase subunit alpha
compare
MMJJ
_RS03045
+0.2
1.2
hypothetical protein
compare
MMJJ
_RS08310
+0.2
1.0
ZIP family metal transporter
compare
MMJJ
_RS07890
+0.2
1.1
pyrimidine dimer DNA glycosylase/endonuclease V
compare
MMJJ
_RS06765
+0.2
1.4
hypothetical protein
compare
MMJJ
_RS09325
+0.2
0.9
hypothetical protein
compare
MMJJ
_RS05405
+0.2
1.3
DNA cytosine methyltransferase
compare
MMJJ
_RS06585
+0.2
1.1
alanine racemase
compare
MMJJ
_RS02310
+0.2
1.1
ABC transporter ATP-binding protein
compare
MMJJ
_RS06080
+0.2
1.2
serine/threonine protein kinase
compare
MMJJ
_RS07685
+0.2
1.5
glycogen/starch synthase
compare
MMJJ
_RS01265
+0.2
0.9
cupin domain-containing protein
compare
MMJJ
_RS04345
+0.2
0.8
DUF2080 family transposase-associated protein
compare
MMJJ
_RS01395
+0.2
1.1
DUF1894 domain-containing protein
compare
MMJJ
_RS00745
+0.2
0.9
hypothetical protein
compare
MMJJ
_RS07815
+0.2
1.2
2-oxoacid:acceptor oxidoreductase family protein
compare
MMJJ
_RS07740
+0.2
1.1
DUF2334 domain-containing protein
compare
MMJJ
_RS05585
+0.2
1.2
hypothetical protein
compare
MMJJ
_RS04410
+0.2
0.6
hypothetical protein
compare
MMJJ
_RS09120
+0.2
0.2
aspartate kinase
compare
MMJJ
_RS05890
+0.2
1.3
molybdate ABC transporter substrate-binding protein
compare
MMJJ
_RS05400
+0.2
0.6
CoA-binding protein
compare
MMJJ
_RS08125
+0.2
1.1
DNA double-strand break repair nuclease NurA
compare
MMJJ
_RS04575
+0.2
0.9
DUF116 domain-containing protein
compare
MMJJ
_RS08455
+0.2
0.7
tetratricopeptide repeat protein
compare
MMJJ
_RS07215
+0.2
1.3
TIGR00341 family protein
compare
MMJJ
_RS03450
+0.2
0.8
hypothetical protein
compare
MMJJ
_RS05335
+0.2
0.7
heavy metal-binding domain-containing protein
compare
MMJJ
_RS07015
+0.2
0.2
PFL family protein
compare
MMJJ
_RS06090
+0.2
0.8
hypothetical protein
compare
MMJJ
_RS05715
+0.2
1.2
phosphoadenosine phosphosulfate reductase family protein
compare
MMJJ
_RS03685
+0.2
1.3
indolepyruvate ferredoxin oxidoreductase subunit alpha
compare
MMJJ
_RS06385
+0.2
0.7
hypothetical protein
compare
MMJJ
_RS05005
+0.2
1.1
hypothetical protein
compare
MMJJ
_RS01630
+0.2
1.1
hypothetical protein
compare
MMJJ
_RS03775
+0.2
0.4
50S ribosomal protein L15e
compare
MMJJ
_RS04920
+0.2
1.1
CBS domain-containing protein
compare
MMJJ
_RS01055
+0.2
0.6
hypothetical protein
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments