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Experiment set3IT055 for
Methanococcus maripaludis JJ
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formate McAA B12 dropout
200 most important genes:
gene
name
fitness
t score
description
MMJJ
_RS05450
-5.4
-22.3
TIGR03576 family pyridoxal phosphate-dependent enzyme
compare
MMJJ
_RS00235
-5.4
-17.6
hypothetical protein
compare
MMJJ
_RS04475
-5.2
-5.0
3,4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMJJ
_RS04200
-5.2
-9.0
triphosphoribosyl-dephospho-CoA synthase
compare
MMJJ
_RS07360
-5.1
-2.4
TIGR00269 family protein
compare
MMJJ
_RS06910
-4.8
-3.1
energy-converting NiFe hydrogenase A subunit EhaA
compare
MMJJ
_RS03875
-4.8
-5.6
CBS domain-containing protein
compare
MMJJ
_RS05070
-4.8
-2.9
DNA primase catalytic subunit PriS
compare
MMJJ
_RS06875
-4.7
-3.7
hypothetical protein
compare
MMJJ
_RS06490
-4.7
-3.2
methanogenesis marker 2 protein
compare
MMJJ
_RS07665
-4.7
-26.5
formate dehydrogenase subunit alpha
compare
MMJJ
_RS06255
-4.7
-6.4
tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3
compare
MMJJ
_RS03895
-4.5
-5.7
hydrogenase expression/formation protein HypE
compare
MMJJ
_RS05995
-4.4
-3.3
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS05445
-4.4
-3.3
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
MMJJ
_RS05650
-4.4
-4.2
formylmethanofuran dehydrogenase subunit B
compare
MMJJ
_RS08020
-4.3
-9.9
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS00580
-4.3
-2.7
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG
compare
MMJJ
_RS07670
-4.3
-19.8
Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain
compare
MMJJ
_RS06175
-4.3
-3.5
DUF1743 domain-containing protein
compare
MMJJ
_RS06695
-4.2
-4.8
amidohydrolase
compare
MMJJ
_RS04485
-4.2
-12.2
riboflavin synthase
compare
MMJJ
_RS07720
-4.2
-3.2
UPF0058 family protein
compare
MMJJ
_RS07660
-4.2
-12.3
carbonic anhydrase
compare
MMJJ
_RS03840
-4.1
-4.9
DHH family phosphoesterase
compare
MMJJ
_RS03670
-4.1
-6.8
precorrin-2 C(20)-methyltransferase
compare
MMJJ
_RS03615
-4.1
-4.6
cobalt-precorrin-8 methylmutase
compare
MMJJ
_RS08250
-4.0
-8.9
hydrogenase maturation peptidase HycI
compare
MMJJ
_RS07655
-4.0
-15.4
hypothetical protein
compare
MMJJ
_RS05380
-4.0
-1.6
hypothetical protein
compare
MMJJ
_RS09375
-4.0
-2.5
hypothetical protein
compare
MMJJ
_RS07950
-3.9
-5.2
4Fe-4S binding protein
compare
MMJJ
_RS03580
-3.9
-4.7
TIGR00303 family protein
compare
MMJJ
_RS08005
-3.9
-17.8
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMJJ
_RS04970
-3.9
-2.7
DUF655 domain-containing protein
compare
MMJJ
_RS07380
-3.8
-13.3
sulfide-dependent adenosine diphosphate thiazole synthase
compare
MMJJ
_RS02045
-3.8
-4.4
molybdenum cofactor guanylyltransferase
compare
MMJJ
_RS05610
-3.8
-6.2
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMJJ
_RS01475
-3.8
-3.0
signal recognition particle-docking protein FtsY
compare
MMJJ
_RS01360
-3.7
-3.2
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMJJ
_RS00450
-3.7
-2.7
DUF126 domain-containing protein
compare
MMJJ
_RS06860
-3.7
-3.4
hypothetical protein
compare
MMJJ
_RS04730
-3.7
-4.0
tyrosine decarboxylase MfnA
compare
MMJJ
_RS05260
-3.6
-8.1
ATP-grasp domain-containing protein
compare
MMJJ
_RS05575
-3.6
-5.8
2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase
compare
MMJJ
_RS06915
-3.6
-17.2
helix-turn-helix domain-containing protein
compare
MMJJ
_RS03820
-3.5
-5.9
hydrogenase formation protein HypD
compare
MMJJ
_RS00370
-3.5
-2.7
asparagine synthase (glutamine-hydrolyzing)
compare
MMJJ
_RS03200
-3.5
-2.7
uroporphyrinogen-III synthase
compare
MMJJ
_RS01600
-3.5
-4.5
radical SAM protein
compare
MMJJ
_RS02920
-3.5
-3.4
30S ribosomal protein S27ae
compare
MMJJ
_RS06040
-3.5
-5.6
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS08625
-3.5
-8.6
magnesium/cobalt transporter CorA
compare
MMJJ
_RS03150
-3.5
-8.8
2-phospho-L-lactate transferase
compare
MMJJ
_RS05225
-3.5
-1.8
Gar1/Naf1 family protein
compare
MMJJ
_RS03125
-3.4
-6.1
GMC oxidoreductase
compare
MMJJ
_RS08320
-3.4
-3.3
CDP-diacylglycerol--serine O-phosphatidyltransferase
compare
MMJJ
_RS04155
-3.4
-9.7
hypothetical protein
compare
MMJJ
_RS06840
-3.4
-5.6
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS06200
-3.4
-3.2
phosphoglycerate dehydrogenase
compare
MMJJ
_RS05535
-3.4
-15.2
hypothetical protein
compare
MMJJ
_RS00205
-3.3
-7.3
adenosylcobinamide-phosphate synthase CbiB
compare
MMJJ
_RS01935
-3.3
-5.4
O-phosphoseryl-tRNA(Sec) selenium transferase
compare
MMJJ
_RS03785
-3.3
-3.4
hypothetical protein
compare
MMJJ
_RS06155
-3.3
-6.4
phosphatidylglycerophosphatase A
compare
MMJJ
_RS01750
-3.3
-4.0
ferrous iron transport protein A
compare
MMJJ
_RS07350
-3.3
-5.0
4Fe-4S binding protein
compare
MMJJ
_RS06725
-3.3
-15.5
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMJJ
_RS05810
-3.3
-9.5
precorrin-4 C(11)-methyltransferase
compare
MMJJ
_RS00215
-3.3
-3.5
CCA tRNA nucleotidyltransferase
compare
MMJJ
_RS00270
-3.3
-4.6
adenosylcobinamide-GDP ribazoletransferase
compare
MMJJ
_RS07785
-3.3
-3.9
fumarate reductase subunit A
compare
MMJJ
_RS08660
-3.3
-4.4
acetylornithine transaminase
compare
MMJJ
_RS00355
-3.2
-3.2
ribonuclease P protein component 4
compare
MMJJ
_RS02040
-3.2
-2.2
Asp-tRNA(Asn) amidotransferase subunit GatC
compare
MMJJ
_RS05490
-3.2
-4.1
imidazole glycerol phosphate synthase subunit HisF
compare
MMJJ
_RS06240
-3.2
-2.8
dihydropteroate synthase-like protein
compare
MMJJ
_RS05620
-3.2
-6.0
CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein
compare
MMJJ
_RS00275
-3.2
-3.2
coenzyme F420-0:L-glutamate ligase
compare
MMJJ
_RS01755
-3.2
-3.2
ferrous iron transport protein B
compare
MMJJ
_RS02090
-3.2
-5.9
tyramine--L-glutamate ligase
compare
MMJJ
_RS08850
-3.2
-3.4
succinate dehydrogenase/fumarate reductase iron-sulfur subunit
compare
MMJJ
_RS00570
-3.2
-2.6
ribonuclease P
compare
MMJJ
_RS08055
-3.1
-7.9
methanogenesis marker 14 protein
compare
MMJJ
_RS03065
-3.1
-11.9
CBS domain-containing protein
compare
MMJJ
_RS07635
-3.1
-15.8
response regulator transcription factor
compare
MMJJ
_RS05950
-3.1
-5.3
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
compare
MMJJ
_RS02200
-3.1
-9.6
chorismate pyruvate-lyase family protein
compare
MMJJ
_RS03055
-3.1
-3.5
hypothetical protein
compare
MMJJ
_RS07705
-3.0
-5.3
GTP-binding protein EngB
compare
MMJJ
_RS06930
-3.0
-3.9
type II methionyl aminopeptidase
compare
MMJJ
_RS03295
-3.0
-15.9
PHP domain-containing protein
compare
MMJJ
_RS07410
-3.0
-5.4
methanogenesis marker protein Mmp4/MtxX
compare
MMJJ
_RS03800
-3.0
-11.3
aldolase
compare
MMJJ
_RS04800
-2.9
-5.5
2-phospho-L-lactate guanylyltransferase
compare
MMJJ
_RS07640
-2.9
-21.7
cache domain-containing protein
compare
MMJJ
_RS04675
-2.9
-7.5
thiamine pyrophosphate-binding protein
compare
MMJJ
_RS05930
-2.9
-2.3
cell division protein SepF
compare
MMJJ
_RS05330
-2.9
-3.6
DNA polymerase II large subunit
compare
MMJJ
_RS04685
-2.9
-10.0
carbamoyltransferase HypF
compare
MMJJ
_RS06625
-2.9
-2.4
pyruvate synthase subunit PorB
compare
MMJJ
_RS03620
-2.9
-5.8
DUF2097 domain-containing protein
compare
MMJJ
_RS08000
-2.8
-8.9
HesA/MoeB/ThiF family protein
compare
MMJJ
_RS03760
-2.8
-2.9
hydrogenase maturation nickel metallochaperone HypA
compare
MMJJ
_RS01690
-2.8
-3.9
methanogenesis marker 12 protein
compare
MMJJ
_RS00475
-2.8
-3.1
bifunctional ornithine acetyltransferase/N-acetylglutamate synthase
compare
MMJJ
_RS06220
-2.8
-5.4
polyamine aminopropyltransferase
compare
MMJJ
_RS07245
-2.8
-6.6
amidohydrolase family protein
compare
MMJJ
_RS03060
-2.8
-3.0
methanogenesis marker 7 protein
compare
MMJJ
_RS08480
-2.8
-8.9
hydroxyethylthiazole kinase
compare
MMJJ
_RS03190
-2.8
-3.6
phosphopyruvate hydratase
compare
MMJJ
_RS08065
-2.7
-3.5
precorrin-6Y C5,15-methyltransferase (decarboxylating) subunit CbiT
compare
MMJJ
_RS08080
-2.7
-9.5
TIGR00300 family protein
compare
MMJJ
_RS03005
-2.7
-5.0
Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit
compare
MMJJ
_RS03830
-2.7
-9.5
CBS domain-containing protein
compare
MMJJ
_RS00560
-2.7
-3.8
homoisocitrate dehydrogenase
compare
MMJJ
_RS08855
-2.7
-5.4
cyclic pyranopterin monophosphate synthase MoaC
compare
MMJJ
_RS01565
-2.7
-6.4
TIGR00267 family protein
compare
MMJJ
_RS04995
-2.7
-6.4
Tfx family DNA-binding protein
compare
MMJJ
_RS04615
-2.7
-5.4
methanogenesis marker 3 protein
compare
MMJJ
_RS06050
-2.7
-12.0
molybdopterin molybdotransferase MoeA
compare
MMJJ
_RS09175
-2.6
-2.0
anthranilate synthase component I
compare
MMJJ
_RS02935
-2.6
-4.4
DNA-directed RNA polymerase subunit E''
compare
MMJJ
_RS06185
-2.6
-5.6
cobalamin biosynthesis protein
compare
MMJJ
_RS07650
-2.6
-18.3
formate/nitrite transporter family protein
compare
MMJJ
_RS05295
-2.6
-11.6
cobyrinic acid a,c-diamide synthase
compare
MMJJ
_RS07000
-2.6
-2.7
TrkH family potassium uptake protein
compare
MMJJ
_RS06510
-2.6
-3.4
LL-diaminopimelate aminotransferase
compare
MMJJ
_RS07995
-2.6
-7.9
molybdenum cofactor biosynthesis protein MoaE
compare
MMJJ
_RS07345
-2.6
-6.8
homocysteine biosynthesis protein
compare
MMJJ
_RS06375
-2.6
-5.9
UbiX family flavin prenyltransferase
compare
MMJJ
_RS07155
-2.6
-9.8
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMJJ
_RS02275
-2.6
-4.0
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS06905
-2.5
-2.7
hypothetical protein
compare
MMJJ
_RS03115
-2.5
-5.7
sulfopyruvate decarboxylase subunit alpha
compare
MMJJ
_RS06835
-2.5
-11.0
4Fe-4S binding protein
compare
MMJJ
_RS06805
-2.5
-3.7
monovalent cation/H+ antiporter subunit E
compare
MMJJ
_RS01865
-2.5
-7.3
peptidyl-tRNA hydrolase Pth2
compare
MMJJ
_RS01870
-2.5
-2.5
methanogenesis marker 15 protein
compare
MMJJ
_RS07970
-2.5
-2.7
O-phospho-L-seryl-tRNA:Cys-tRNA synthase
compare
MMJJ
_RS06785
-2.5
-7.7
RNA ligase partner protein
compare
MMJJ
_RS03815
-2.5
-2.7
nascent polypeptide-associated complex protein
compare
MMJJ
_RS07945
-2.4
-3.1
4Fe-4S binding protein
compare
MMJJ
_RS03630
-2.4
-11.5
AMP phosphorylase
compare
MMJJ
_RS06855
-2.4
-1.8
DUF2104 domain-containing protein
compare
MMJJ
_RS08340
-2.4
-4.0
archaeoflavoprotein AfpA
compare
MMJJ
_RS00360
-2.4
-3.7
adenosylhomocysteinase
compare
MMJJ
_RS08330
-2.4
-2.9
SufD family Fe-S cluster assembly protein
compare
MMJJ
_RS01355
-2.4
-4.3
UDP-N-acetyl-D-mannosamine dehydrogenase
compare
MMJJ
_RS01345
-2.4
-4.8
(5-formylfuran-3-yl)methyl phosphate synthase
compare
MMJJ
_RS04655
-2.4
-6.8
FAD-dependent oxidoreductase
compare
MMJJ
_RS03095
-2.4
-3.1
bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase
compare
MMJJ
_RS05190
-2.4
-7.3
gamma carbonic anhydrase family protein
compare
MMJJ
_RS04790
-2.4
-5.0
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMJJ
_RS05655
-2.3
-6.6
HisA/HisF family protein
compare
MMJJ
_RS06180
-2.3
-3.5
tryptophan--tRNA ligase
compare
MMJJ
_RS04670
-2.3
-4.7
DUF2117 domain-containing protein
compare
MMJJ
_RS07840
-2.3
-2.4
Glu-tRNA(Gln) amidotransferase subunit GatD
compare
MMJJ
_RS04520
-2.3
-4.4
coenzyme F430 synthase
compare
MMJJ
_RS06225
-2.3
-3.0
adenosylmethionine decarboxylase
compare
MMJJ
_RS01810
-2.3
-2.5
methyl coenzyme M reductase system, component A2
compare
MMJJ
_RS06880
-2.3
-2.1
EhaG family protein
compare
MMJJ
_RS09190
-2.3
-2.0
tryptophan synthase subunit beta
compare
MMJJ
_RS04050
-2.3
-2.7
dihydroneopterin aldolase family protein
compare
MMJJ
_RS06215
-2.2
-5.3
agmatinase
compare
MMJJ
_RS03110
-2.2
-4.9
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase
compare
MMJJ
_RS06250
-2.2
-3.2
nicotinamide-nucleotide adenylyltransferase
compare
MMJJ
_RS05065
-2.2
-4.5
(4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase
compare
MMJJ
_RS04985
-2.2
-4.2
glutamyl-tRNA reductase
compare
MMJJ
_RS01820
-2.2
-6.0
MJ1244 family protein
compare
MMJJ
_RS08095
-2.2
-4.1
cobyric acid synthase CobQ
compare
MMJJ
_RS07190
-2.2
-5.0
RtcB family protein
compare
MMJJ
_RS08430
-2.2
-6.8
small nuclear ribonucleoprotein
compare
MMJJ
_RS08155
-2.2
-4.0
cobalt-precorrin-5B (C(1))-methyltransferase CbiD
compare
MMJJ
_RS05375
-2.2
-15.1
radical SAM protein
compare
MMJJ
_RS03230
-2.2
-3.1
NAD(P)/FAD-dependent oxidoreductase
compare
MMJJ
_RS08620
-2.2
-3.6
DUF373 family protein
compare
MMJJ
_RS07430
-2.2
-5.2
ribonuclease VapC
compare
MMJJ
_RS01200
-2.2
-3.6
PRC-barrel domain-containing protein
compare
MMJJ
_RS00195
-2.2
-3.6
precorrin-3B C(17)-methyltransferase
compare
MMJJ
_RS00600
-2.1
-3.6
hydroxymethylbilane synthase
compare
MMJJ
_RS05590
-2.1
-2.5
homoserine dehydrogenase
compare
MMJJ
_RS05720
-2.1
-3.1
glutamine--fructose-6-phosphate transaminase (isomerizing)
compare
MMJJ
_RS04010
-2.1
-7.1
archaeal proteasome endopeptidase complex subunit alpha
compare
MMJJ
_RS08840
-2.1
-3.8
calcium/sodium antiporter
compare
MMJJ
_RS03660
-2.1
-4.8
DUF447 family protein
compare
MMJJ
_RS01815
-2.1
-3.8
DUF134 domain-containing protein
compare
MMJJ
_RS04150
-2.1
-3.2
DUF5379 domain-containing protein
compare
MMJJ
_RS06760
-2.0
-4.8
Ni-sirohydrochlorin a,c-diamide synthase
compare
MMJJ
_RS07725
-2.0
-6.2
DNA primase DnaG
compare
MMJJ
_RS07355
-2.0
-7.1
MoaD/ThiS family protein
compare
MMJJ
_RS06865
-2.0
-2.6
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS03810
-2.0
-2.7
AIR synthase-related protein
compare
MMJJ
_RS01880
-2.0
-3.7
RlmE family RNA methyltransferase
compare
MMJJ
_RS05935
-2.0
-2.4
Era-like GTP-binding protein
compare
MMJJ
_RS00050
-2.0
-9.8
AAA family ATPase
compare
MMJJ
_RS04595
-1.9
-5.1
hypothetical protein
compare
MMJJ
_RS06485
-1.9
-2.0
phosphoglycerate kinase
compare
MMJJ
_RS03270
-1.9
-1.9
ribosome biogenesis/translation initiation ATPase RLI
compare
MMJJ
_RS05540
-1.9
-13.4
LysR family transcriptional regulator
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments