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Experiment set3IT054 for
Methanococcus maripaludis JJ
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formate McAA pantothenate dropout
200 most detrimental genes:
gene
name
fitness
t score
description
MMJJ
_RS04415
+2.9
14.4
hypothetical protein
compare
MMJJ
_RS08935
+1.0
1.8
TIGR00288 family NYN domain-containing protein
compare
MMJJ
_RS04005
+0.9
6.7
acetate--CoA ligase family protein
compare
MMJJ
_RS08830
+0.9
3.4
hypothetical protein
compare
MMJJ
_RS07750
+0.8
1.7
class III signal peptide-containing protein
compare
MMJJ
_RS09120
+0.8
1.4
aspartate kinase
compare
MMJJ
_RS04545
+0.8
2.4
PadR family transcriptional regulator
compare
MMJJ
_RS08225
+0.7
4.4
peptidylprolyl isomerase
compare
MMJJ
_RS06505
+0.7
3.1
prephenate dehydratase
compare
MMJJ
_RS03725
+0.6
2.5
sulfurtransferase TusA family protein
compare
MMJJ
_RS01590
+0.6
1.9
adenine phosphoribosyltransferase
compare
MMJJ
_RS06680
+0.6
3.3
DUF366 family protein
compare
MMJJ
_RS06675
+0.6
4.4
TIGR01212 family radical SAM protein
compare
MMJJ
_RS07185
+0.6
1.4
DUF371 domain-containing protein
compare
MMJJ
_RS07230
+0.6
3.4
coenzyme F420-reducing hydrogenase, FrhD protein
compare
MMJJ
_RS07795
+0.6
3.1
cupin domain-containing protein
compare
MMJJ
_RS07235
+0.6
4.5
coenzyme F420 hydrogenase subunit alpha
compare
MMJJ
_RS07025
+0.5
2.9
tRNA (cytidine(56)-2'-O)-methyltransferase
compare
MMJJ
_RS06460
+0.5
3.2
cytochrome c
compare
MMJJ
_RS07260
+0.5
3.1
PspC domain-containing protein
compare
MMJJ
_RS07225
+0.5
3.6
coenzyme F420 hydrogenase subunit gamma
compare
MMJJ
_RS07595
+0.5
2.6
hypothetical protein
compare
MMJJ
_RS07220
+0.5
4.0
coenzyme F420 hydrogenase subunit beta
compare
MMJJ
_RS07015
+0.5
1.0
PFL family protein
compare
MMJJ
_RS01140
+0.5
1.9
helix-turn-helix domain-containing protein
compare
MMJJ
_RS04345
+0.5
2.2
DUF2080 family transposase-associated protein
compare
MMJJ
_RS06090
+0.5
2.9
hypothetical protein
compare
MMJJ
_RS05040
+0.5
3.2
7-carboxy-7-deazaguanine synthase QueE
compare
MMJJ
_RS06385
+0.5
2.3
hypothetical protein
compare
MMJJ
_RS04375
+0.5
1.4
hypothetical protein
compare
MMJJ
_RS06640
+0.5
3.3
YfcE family phosphodiesterase
compare
MMJJ
_RS01785
+0.5
0.8
50S ribosomal protein L14e
compare
MMJJ
_RS04955
+0.5
3.2
tRNA pseudouridine(54/55) synthase Pus10
compare
MMJJ
_RS06515
+0.4
3.4
ribonuclease III
compare
MMJJ
_RS05975
+0.4
3.1
sulfurtransferase TusA family protein
compare
MMJJ
_RS06190
+0.4
3.4
7-cyano-7-deazaguanine synthase
compare
MMJJ
_RS06950
+0.4
3.2
4-demethylwyosine synthase TYW1
compare
MMJJ
_RS01790
+0.4
3.1
pyridoxamine 5'-phosphate oxidase family protein
compare
MMJJ
_RS06470
+0.4
3.1
tripartite tricarboxylate transporter permease
compare
MMJJ
_RS09365
+0.4
1.2
hypothetical protein
compare
MMJJ
_RS01670
+0.4
1.9
hypothetical protein
compare
MMJJ
_RS07240
+0.4
3.7
MBL fold metallo-hydrolase
compare
MMJJ
_RS06810
+0.4
3.2
L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha
compare
MMJJ
_RS03605
+0.4
1.6
TIGR00297 family protein
compare
MMJJ
_RS06800
+0.4
2.0
prefoldin subunit alpha
compare
MMJJ
_RS06590
+0.4
3.3
sodium:alanine symporter family protein
compare
MMJJ
_RS07205
+0.4
2.1
MTH895/ArsE family thioredoxin-like protein
compare
MMJJ
_RS07920
+0.4
2.8
6-carboxytetrahydropterin synthase QueD
compare
MMJJ
_RS07270
+0.4
2.6
ribonuclease HII
compare
MMJJ
_RS08100
+0.4
2.3
hypothetical protein
compare
MMJJ
_RS06770
+0.4
3.0
hypothetical protein
compare
MMJJ
_RS06440
+0.4
2.8
DUF4870 domain-containing protein
compare
MMJJ
_RS04105
+0.4
3.1
prepilin peptidase
compare
MMJJ
_RS06280
+0.4
3.1
hypothetical protein
compare
MMJJ
_RS06205
+0.4
2.5
EamA family transporter
compare
MMJJ
_RS08445
+0.4
1.8
cell division ATPase MinD
compare
MMJJ
_RS06430
+0.4
2.2
haloacid dehalogenase
compare
MMJJ
_RS09405
+0.4
1.1
hypothetical protein
compare
MMJJ
_RS02270
+0.4
2.4
HEPN domain-containing protein
compare
MMJJ
_RS07210
+0.4
2.7
AmmeMemoRadiSam system protein B
compare
MMJJ
_RS09295
+0.4
0.5
hypothetical protein
compare
MMJJ
_RS06500
+0.4
2.6
class I SAM-dependent methyltransferase
compare
MMJJ
_RS05685
+0.4
2.4
class III signal peptide-containing protein
compare
MMJJ
_RS06740
+0.3
1.8
energy-coupling factor ABC transporter substrate-binding protein
compare
MMJJ
_RS06445
+0.3
3.0
hypothetical protein
compare
MMJJ
_RS05525
+0.3
1.8
GTP-binding protein
compare
MMJJ
_RS05700
+0.3
2.3
metallophosphoesterase
compare
MMJJ
_RS06455
+0.3
2.5
YeeE/YedE family protein
compare
MMJJ
_RS07450
+0.3
2.0
hypothetical protein
compare
MMJJ
_RS04815
+0.3
1.8
TIM barrel protein
compare
MMJJ
_RS03835
+0.3
1.2
DUF504 domain-containing protein
compare
MMJJ
_RS01855
+0.3
2.4
MBL fold metallo-hydrolase
compare
MMJJ
_RS06960
+0.3
2.9
CAP domain-containing protein
compare
MMJJ
_RS07480
+0.3
2.6
FAD-dependent oxidoreductase
compare
MMJJ
_RS06085
+0.3
1.4
proteasome assembly chaperone family protein
compare
MMJJ
_RS08195
+0.3
1.9
DUF4186 domain-containing protein
compare
MMJJ
_RS06685
+0.3
2.7
S-layer protein
compare
MMJJ
_RS06790
+0.3
2.6
nucleotidyltransferase family protein
compare
MMJJ
_RS01035
+0.3
1.6
hypothetical protein
compare
MMJJ
_RS06130
+0.3
1.6
hypothetical protein
compare
MMJJ
_RS08365
+0.3
2.1
DsrE family protein
compare
MMJJ
_RS06100
+0.3
2.0
rubrerythrin
compare
MMJJ
_RS04350
+0.3
1.8
hypothetical protein
compare
MMJJ
_RS05530
+0.3
1.1
roadblock/LC7 domain-containing protein
compare
MMJJ
_RS00405
+0.3
2.1
flavodoxin family protein
compare
MMJJ
_RS07495
+0.3
1.8
4Fe-4S binding protein
compare
MMJJ
_RS06765
+0.3
2.4
hypothetical protein
compare
MMJJ
_RS06045
+0.3
2.3
hypothetical protein
compare
MMJJ
_RS06520
+0.3
2.1
TldD/PmbA family protein
compare
MMJJ
_RS09065
+0.3
2.0
hypothetical protein
compare
MMJJ
_RS07810
+0.3
1.9
3-methyl-2-oxobutanoate dehydrogenase subunit VorB
compare
MMJJ
_RS04215
+0.3
2.4
DMT family transporter
compare
MMJJ
_RS03595
+0.3
1.7
hypothetical protein
compare
MMJJ
_RS07815
+0.3
2.0
2-oxoacid:acceptor oxidoreductase family protein
compare
MMJJ
_RS06735
+0.3
2.0
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS02180
+0.3
1.4
DHH family phosphoesterase
compare
MMJJ
_RS07365
+0.3
2.2
CatB-related O-acetyltransferase
compare
MMJJ
_RS05390
+0.3
2.0
tRNA pseudouridine(13) synthase TruD
compare
MMJJ
_RS06580
+0.3
2.2
alanine dehydrogenase
compare
MMJJ
_RS00145
+0.3
2.1
aquaporin family protein
compare
MMJJ
_RS06275
+0.3
0.9
hypothetical protein
compare
MMJJ
_RS09360
+0.3
1.7
hypothetical protein
compare
MMJJ
_RS03375
+0.3
1.1
hypothetical protein
compare
MMJJ
_RS02160
+0.3
1.7
amino acid ABC transporter permease
compare
MMJJ
_RS07010
+0.3
1.3
preprotein translocase subunit Sec61beta
compare
MMJJ
_RS06585
+0.3
1.7
alanine racemase
compare
MMJJ
_RS04585
+0.3
1.7
phenylacetate--CoA ligase
compare
MMJJ
_RS07800
+0.3
2.1
AMP-binding protein
compare
MMJJ
_RS08670
+0.3
2.0
phosphate signaling complex protein PhoU
compare
MMJJ
_RS06285
+0.3
1.7
YchF/TatD family DNA exonuclease
compare
MMJJ
_RS05990
+0.3
1.5
phosphatase PAP2 family protein
compare
MMJJ
_RS06120
+0.3
1.7
DUF4013 domain-containing protein
compare
MMJJ
_RS03525
+0.3
1.9
2-hydroxyacyl-CoA dehydratase family protein
compare
MMJJ
_RS03290
+0.3
2.1
amidohydrolase
compare
MMJJ
_RS07215
+0.3
2.0
TIGR00341 family protein
compare
MMJJ
_RS02230
+0.3
2.1
hypothetical protein
compare
MMJJ
_RS08305
+0.3
1.4
peroxiredoxin
compare
MMJJ
_RS06450
+0.2
1.7
DUF3343 domain-containing protein
compare
MMJJ
_RS07445
+0.2
1.8
RlmF-related methyltransferase
compare
MMJJ
_RS07760
+0.2
1.4
GNAT family N-acetyltransferase
compare
MMJJ
_RS06210
+0.2
1.6
hypothetical protein
compare
MMJJ
_RS04625
+0.2
1.7
SLC13 family permease
compare
MMJJ
_RS07835
+0.2
1.4
UPF0489 family protein
compare
MMJJ
_RS04610
+0.2
0.9
ribosome assembly RNA-binding protein YhbY
compare
MMJJ
_RS07200
+0.2
1.9
MFS transporter
compare
MMJJ
_RS08015
+0.2
1.3
HAD family hydrolase
compare
MMJJ
_RS01010
+0.2
2.2
right-handed parallel beta-helix repeat-containing protein
compare
MMJJ
_RS07820
+0.2
1.8
bifunctional hexulose-6-phosphate synthase/ribonuclease regulator
compare
MMJJ
_RS08525
+0.2
1.0
peptidylprolyl isomerase
compare
MMJJ
_RS07915
+0.2
1.2
CBS domain-containing protein
compare
MMJJ
_RS06235
+0.2
1.8
IGHMBP2 family helicase
compare
MMJJ
_RS05235
+0.2
2.0
Flp pilus assembly complex ATPase component TadA
compare
MMJJ
_RS07695
+0.2
1.8
glycoside hydrolase family 15 protein
compare
MMJJ
_RS05580
+0.2
1.2
methanogenesis marker 9 domain-containing protein
compare
MMJJ
_RS06535
+0.2
1.8
UPF0104 family protein
compare
MMJJ
_RS09325
+0.2
1.2
hypothetical protein
compare
MMJJ
_RS01405
+0.2
0.2
proline--tRNA ligase
compare
MMJJ
_RS05835
+0.2
1.8
bis-aminopropyl spermidine synthase family protein
compare
MMJJ
_RS06710
+0.2
1.7
TldD/PmbA family protein
compare
MMJJ
_RS03040
+0.2
1.5
lactate utilization protein
compare
MMJJ
_RS08400
+0.2
0.7
CoB--CoM heterodisulfide reductase subunit C
compare
MMJJ
_RS01825
+0.2
1.0
DNA repair and recombination protein RadB
compare
MMJJ
_RS05410
+0.2
1.4
RecB-family nuclease
compare
MMJJ
_RS02170
+0.2
1.3
2-thiouracil desulfurase family protein
compare
MMJJ
_RS07005
+0.2
0.7
transcription factor S
compare
MMJJ
_RS01955
+0.2
1.8
hypothetical protein
compare
MMJJ
_RS09255
+0.2
0.7
hypothetical protein
compare
MMJJ
_RS06115
+0.2
1.5
pyruvate kinase
compare
MMJJ
_RS08685
+0.2
1.5
phosphate ABC transporter permease subunit PstC
compare
MMJJ
_RS03515
+0.2
1.3
GPR1/FUN34/YaaH family transporter
compare
MMJJ
_RS05500
+0.2
1.8
hypothetical protein
compare
MMJJ
_RS03175
+0.2
1.2
zinc metalloprotease HtpX
compare
MMJJ
_RS08270
+0.2
1.7
iron ABC transporter substrate-binding protein
compare
MMJJ
_RS07610
+0.2
1.3
DUF2119 domain-containing protein
compare
MMJJ
_RS09015
+0.2
1.3
SPFH domain-containing protein
compare
MMJJ
_RS08665
+0.2
1.7
transcriptional regulator
compare
MMJJ
_RS03775
+0.2
0.9
50S ribosomal protein L15e
compare
MMJJ
_RS08350
+0.2
1.7
heavy metal translocating P-type ATPase
compare
MMJJ
_RS04390
+0.2
1.6
rhomboid family intramembrane serine protease
compare
MMJJ
_RS07885
+0.2
1.4
NERD domain-containing protein
compare
MMJJ
_RS05520
+0.2
1.5
H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein
compare
MMJJ
_RS00640
+0.2
1.6
glycine betaine ABC transporter substrate-binding protein
compare
MMJJ
_RS00155
+0.2
1.6
DUF2193 domain-containing protein
compare
MMJJ
_RS02895
+0.2
1.4
ATP-binding protein
compare
MMJJ
_RS04525
+0.2
0.9
hypothetical protein
compare
MMJJ
_RS02110
+0.2
1.0
carboxymuconolactone decarboxylase family protein
compare
MMJJ
_RS05510
+0.2
1.4
archaellum operon transcriptional activator EarA family protein
compare
MMJJ
_RS05660
+0.2
1.1
sulfopyruvate decarboxylase subunit beta
compare
MMJJ
_RS07255
+0.2
1.6
hypothetical protein
compare
MMJJ
_RS05150
+0.2
1.3
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH
compare
MMJJ
_RS06745
+0.2
1.1
energy-coupling factor ABC transporter permease
compare
MMJJ
_RS04855
+0.2
1.3
ECF transporter S component
compare
MMJJ
_RS04500
+0.2
1.2
hypothetical protein
compare
MMJJ
_RS08300
+0.2
1.4
hypothetical protein
compare
MMJJ
_RS03330
+0.2
1.3
hypothetical protein
compare
MMJJ
_RS05340
+0.2
1.4
AAA family ATPase
compare
MMJJ
_RS03850
+0.2
0.7
nucleoside-diphosphate kinase
compare
MMJJ
_RS06055
+0.2
1.3
S-methyl-5-thioribose-1-phosphate isomerase
compare
MMJJ
_RS07590
+0.2
1.3
flap endonuclease-1
compare
MMJJ
_RS05695
+0.2
0.7
class III signal peptide-containing protein
compare
MMJJ
_RS03015
+0.2
1.3
Ig-like domain-containing protein
compare
MMJJ
_RS04850
+0.2
1.1
energy-coupling factor transporter transmembrane protein EcfT
compare
MMJJ
_RS08410
+0.2
0.4
CBS domain-containing protein
compare
MMJJ
_RS02880
+0.2
1.3
hypothetical protein
compare
MMJJ
_RS04870
+0.2
0.3
tRNA-Asp
compare
MMJJ
_RS09005
+0.2
1.5
N-6 DNA methylase
compare
MMJJ
_RS03575
+0.2
0.8
NUDIX hydrolase
compare
MMJJ
_RS01375
+0.2
1.2
tetrahydromethanopterin:alpha-L-glutamate ligase
compare
MMJJ
_RS04420
+0.2
1.3
type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family
compare
MMJJ
_RS05715
+0.2
1.4
phosphoadenosine phosphosulfate reductase family protein
compare
MMJJ
_RS07865
+0.2
0.9
zinc ribbon domain-containing protein
compare
MMJJ
_RS06080
+0.2
1.3
serine/threonine protein kinase
compare
MMJJ
_RS05585
+0.2
1.2
hypothetical protein
compare
MMJJ
_RS07890
+0.2
1.0
pyrimidine dimer DNA glycosylase/endonuclease V
compare
MMJJ
_RS08310
+0.2
0.9
ZIP family metal transporter
compare
MMJJ
_RS08485
+0.2
0.9
Lrp/AsnC family transcriptional regulator
compare
MMJJ
_RS00900
+0.2
0.7
PC4/YdbC family ssDNA-binding protein
compare
MMJJ
_RS01210
+0.2
0.5
hypothetical protein
compare
MMJJ
_RS08455
+0.2
0.7
tetratricopeptide repeat protein
compare
MMJJ
_RS08810
+0.2
0.2
DUF4040 domain-containing protein
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments