Experiment set3IT053 for Pseudomonas fluorescens FW300-N2E2

Compare to:

LB with D-Cycloserine 0.12 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
Pf6N2E2_4541 +1.3 2.2 hypothetical protein compare
Pf6N2E2_5178 +1.3 2.2 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) compare
Pf6N2E2_2225 +1.3 3.4 FIG00953489: hypothetical protein compare
Pf6N2E2_746 +1.3 1.9 FIG00958097: hypothetical protein compare
Pf6N2E2_952 +1.2 1.9 putative exported protein compare
Pf6N2E2_1626 +1.1 5.7 Putative ATP-binding component of a transport system compare
Pf6N2E2_2367 +1.1 2.5 hypothetical protein compare
Pf6N2E2_339 +1.0 2.9 Glutathione-regulated potassium-efflux system protein KefC compare
Pf6N2E2_2477 +1.0 1.5 ABC transporter ATP-binding protein YvcR compare
Pf6N2E2_5279 +1.0 4.5 Hypothetical flavoprotein YqcA (clustered with tRNA pseudouridine synthase C) compare
Pf6N2E2_4146 +1.0 3.1 Membrane lipoprotein lipid attachment site containing protein USSDB6D compare
Pf6N2E2_285 +0.9 2.9 FIG002903: a protein of unknown function perhaps involved in purine metabolism compare
Pf6N2E2_2519 +0.9 1.0 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) compare
Pf6N2E2_2688 +0.9 3.3 YD repeat protein compare
Pf6N2E2_3529 +0.8 2.2 Toxin A compare
Pf6N2E2_2752 +0.8 5.1 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_1876 +0.8 2.3 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) compare
Pf6N2E2_3237 +0.8 2.4 hypothetical protein compare
Pf6N2E2_4963 +0.8 1.6 Homoserine dehydrogenase (EC 1.1.1.3) compare
Pf6N2E2_238 +0.8 1.5 hypothetical protein compare
Pf6N2E2_728 +0.8 1.8 Nitrate/nitrite transporter compare
Pf6N2E2_3055 +0.8 2.6 Ribonuclease HII (EC 3.1.26.4) compare
Pf6N2E2_2114 +0.8 2.3 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf6N2E2_5013 +0.8 1.6 Putative membrane protein compare
Pf6N2E2_373 +0.8 3.2 Gamma-aminobutyrate:alpha-ketoglutarate aminotransferase (EC 2.6.1.19) compare
Pf6N2E2_3338 +0.8 1.8 1-phosphofructokinase (EC 2.7.1.56) compare
Pf6N2E2_3204 +0.8 2.0 Rho-specific inhibitor of transcription termination (YaeO) compare
Pf6N2E2_1617 +0.8 1.1 COG2199: FOG: GGDEF domain compare
Pf6N2E2_3550 +0.8 1.7 Urea ABC transporter, ATPase protein UrtD compare
Pf6N2E2_2536 +0.8 1.1 Fumarate hydratase class II (EC 4.2.1.2) compare
Pf6N2E2_1575 +0.8 3.2 FIG00967398: hypothetical protein compare
Pf6N2E2_172 +0.8 2.9 FIG00953292: hypothetical protein compare
Pf6N2E2_865 +0.8 1.7 Fumarylacetoacetate hydrolase family protein compare
Pf6N2E2_2247 +0.7 1.7 Transcriptional regulator, AraC family compare
Pf6N2E2_3546 +0.7 2.6 ABC transporter (iron.B12.siderophore.hemin) , permease component compare
Pf6N2E2_4751 +0.7 2.9 response regulator compare
Pf6N2E2_1199 +0.7 1.4 hypothetical protein compare
Pf6N2E2_4181 +0.7 1.3 Organic hydroperoxide resistance protein compare
Pf6N2E2_4483 +0.7 6.3 Ferric iron ABC transporter, iron-binding protein compare
Pf6N2E2_3325 +0.7 1.9 ABC transporter, ATP-binding protein compare
Pf6N2E2_331 +0.7 1.5 Putative translation initiation inhibitor, yjgF family compare
Pf6N2E2_5578 +0.7 4.5 Ferric iron ABC transporter, ATP-binding protein compare
Pf6N2E2_2778 +0.7 2.7 Urea carboxylase-related aminomethyltransferase (EC 2.1.2.10) compare
Pf6N2E2_3134 +0.7 0.9 hypothetical protein compare
Pf6N2E2_1627 +0.7 4.9 Non-ribosomal peptide synthase compare
Pf6N2E2_1743 +0.7 2.1 Putrescine transport ATP-binding protein PotA (TC 3.A.1.11.1) compare
Pf6N2E2_1339 +0.7 1.7 Acetylornithine deacetylase (EC 3.5.1.16) compare
Pf6N2E2_4673 +0.7 2.5 ATP-dependent 23S rRNA helicase DbpA compare
Pf6N2E2_5989 +0.7 5.7 Transcriptional regulator, GntR family domain / Aspartate aminotransferase (EC 2.6.1.1) compare
Pf6N2E2_5714 +0.7 1.3 Flavoprotein WrbA compare
Pf6N2E2_5841 +0.7 1.0 GlcG protein compare
Pf6N2E2_1294 +0.7 0.9 Carbon starvation protein A compare
Pf6N2E2_4982 +0.7 2.8 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase (EC 6.3.2.-) compare
Pf6N2E2_5583 +0.7 3.5 Bacterioferritin compare
Pf6N2E2_5012 +0.7 3.0 FIG00954871: hypothetical protein compare
Pf6N2E2_216 +0.7 2.9 Copper-sensing two-component system response regulator CpxR compare
Pf6N2E2_5758 +0.7 1.8 FIG00957314: hypothetical protein compare
Pf6N2E2_1685 +0.7 2.6 Vitamin B12 ABC transporter, B12-binding component BtuF compare
Pf6N2E2_1715 +0.7 1.8 hypothetical protein compare
Pf6N2E2_5720 +0.7 5.2 BarA sensory histidine kinase (= VarS = GacS) compare
Pf6N2E2_2795 +0.6 1.2 putative exported protein compare
Pf6N2E2_4484 +0.6 5.5 Ferric iron ABC transporter, permease protein compare
Pf6N2E2_1169 +0.6 1.4 TnpR protein compare
Pf6N2E2_2059 +0.6 1.9 ChlI component of cobalt chelatase involved in B12 biosynthesis compare
Pf6N2E2_5392 +0.6 1.6 Molybdenum cofactor biosynthesis protein MoaC compare
Pf6N2E2_1141 +0.6 1.6 Lipid-A-disaccharide synthase (EC 2.4.1.182) compare
Pf6N2E2_5130 +0.6 1.7 hypothetical protein compare
Pf6N2E2_5816 +0.6 1.1 Smr domain protein compare
Pf6N2E2_6030 +0.6 2.6 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_2038 +0.6 2.1 Transcriptional regulator, TetR family compare
Pf6N2E2_2480 +0.6 1.3 FIG00957636: hypothetical protein compare
Pf6N2E2_4694 +0.6 2.2 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain compare
Pf6N2E2_4427 +0.6 1.6 FIG00954215: hypothetical protein compare
Pf6N2E2_2707 +0.6 2.1 Allophanate hydrolase 2 subunit 1 (EC 3.5.1.54) compare
Pf6N2E2_4121 +0.6 3.2 Ribosomal RNA small subunit methyltransferase B (EC 2.1.1.-) compare
Pf6N2E2_1065 +0.6 2.0 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
Pf6N2E2_482 +0.6 1.8 Transcriptional regulator BkdR of isoleucine and valine catabolism operon compare
Pf6N2E2_5131 +0.6 2.4 Methyl-accepting chemotaxis protein I (serine chemoreceptor protein) compare
Pf6N2E2_3321 +0.6 3.2 Ornithine cyclodeaminase (EC 4.3.1.12) compare
Pf6N2E2_1488 +0.6 2.7 hypothetical protein compare
Pf6N2E2_4188 +0.6 2.6 DNA-3-methyladenine glycosylase (EC 3.2.2.20) compare
Pf6N2E2_3737 +0.6 1.8 General secretion pathway protein M compare
Pf6N2E2_160 +0.6 1.5 hypothetical protein compare
Pf6N2E2_956 +0.6 2.0 FIG01210404: hypothetical protein compare
Pf6N2E2_28 +0.6 1.6 4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein compare
Pf6N2E2_3183 +0.6 2.2 Believed to be involved in assembly of Fe-S clusters compare
Pf6N2E2_2350 +0.6 1.8 Oxygen-regulated invasion protein OrgB compare
Pf6N2E2_987 +0.6 1.2 hypothetical protein compare
Pf6N2E2_5522 +0.6 1.8 FIG001943: hypothetical protein YajQ compare
Pf6N2E2_3591 +0.6 2.1 NUDIX hydrolase compare
Pf6N2E2_204 +0.6 0.7 hypothetical protein compare
Pf6N2E2_1754 +0.6 1.4 FIG00731982: hypothetical protein compare
Pf6N2E2_2722 +0.6 2.0 FIG00954807: hypothetical protein compare
Pf6N2E2_4943 +0.6 1.8 PspA/IM30 family protein compare
Pf6N2E2_6087 +0.6 1.5 Short-chain dehydrogenase/reductase SDR compare
Pf6N2E2_597 +0.6 2.1 FIG00953564: hypothetical protein compare
Pf6N2E2_3729 +0.6 1.8 FIG138576: 3-oxoacyl-[ACP] synthase (EC 2.3.1.41) compare
Pf6N2E2_5345 +0.6 3.0 LppC putative lipoprotein compare
Pf6N2E2_103 +0.6 1.9 Various polyols ABC transporter, ATP-binding component compare
Pf6N2E2_1598 +0.6 1.9 Nitrate reductase cytochrome c550-type subunit compare
Pf6N2E2_5992 +0.6 2.8 Collagenase and related proteases compare
Pf6N2E2_6019 +0.6 2.4 putative oxidoreductase compare
Pf6N2E2_1089 +0.5 1.3 Delta 1-piperideine-2-carboxylate reductase (EC 1.5.1.21) / Delta 1-pyrroline-2-carboxylate reductase (EC 1.5.1.1) compare
Pf6N2E2_89 +0.5 1.1 hypothetical protein compare
Pf6N2E2_5794 +0.5 1.2 Ribosomal large subunit pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_1514 +0.5 1.7 lipoprotein OprI, putative compare
Pf6N2E2_3950 +0.5 2.8 Efflux membrane fusion protein, RND family compare
Pf6N2E2_4145 +0.5 1.7 ABC-type transport system involved in resistance to organic solvents, periplasmic component USSDB6C compare
Pf6N2E2_2110 +0.5 2.3 LysR family transcriptional regulator near succinyl-CoA:3-ketoacid-coenzyme A transferase compare
Pf6N2E2_2065 +0.5 1.4 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) compare
Pf6N2E2_2831 +0.5 2.1 3-carboxy-cis,cis-muconate cycloisomerase (EC 5.5.1.2) compare
Pf6N2E2_5226 +0.5 0.7 FIG00955589: hypothetical protein compare
Pf6N2E2_3835 +0.5 2.7 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_5671 +0.5 1.8 Succinylglutamate desuccinylase (EC 3.5.1.96) compare
Pf6N2E2_1625 +0.5 1.8 Ferric reductase (1.6.99.14) compare
Pf6N2E2_2022 +0.5 2.9 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf6N2E2_1197 +0.5 2.1 Octaprenyl diphosphate synthase (EC 2.5.1.90) / Dimethylallyltransferase (EC 2.5.1.1) / (2E,6E)-farnesyl diphosphate synthase (EC 2.5.1.10) / Geranylgeranyl diphosphate synthase (EC 2.5.1.29) compare
Pf6N2E2_5613 +0.5 0.8 FIG00953674: hypothetical protein compare
Pf6N2E2_3206 +0.5 0.7 hypothetical protein compare
Pf6N2E2_2424 +0.5 1.3 Molybdopterin-guanine dinucleotide biosynthesis protein MobA compare
Pf6N2E2_5174 +0.5 1.7 Glycosyltransferase compare
Pf6N2E2_1085 +0.5 1.2 Fe2+/Zn2+ uptake regulation proteins compare
Pf6N2E2_3271 +0.5 0.8 Phosphocarrier protein, nitrogen regulation associated compare
Pf6N2E2_1759 +0.5 1.3 uncharacterized domain 1 compare
Pf6N2E2_1221 +0.5 2.1 sodium/hydrogen exchanger family protein compare
Pf6N2E2_5328 +0.5 1.8 FIG00958649: hypothetical protein compare
Pf6N2E2_2572 +0.5 1.4 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
Pf6N2E2_1212 +0.5 2.0 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_5830 +0.5 2.1 FIG00960829: hypothetical protein compare
Pf6N2E2_923 +0.5 1.2 Haloacid dehalogenase, type II (EC 3.8.1.2) compare
Pf6N2E2_750 +0.5 1.3 Transcriptional regulator, DeoR family compare
Pf6N2E2_1342 +0.5 1.6 monooxygenase, putative compare
Pf6N2E2_600 +0.5 1.0 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases compare
Pf6N2E2_136 +0.5 1.2 Glycolate dehydrogenase (EC 1.1.99.14), FAD-binding subunit GlcE compare
Pf6N2E2_4540 +0.5 1.4 hypothetical protein compare
Pf6N2E2_1281 +0.5 1.2 ATPase involved in DNA repair compare
Pf6N2E2_5617 +0.5 3.3 Iron-regulated protein A precursor compare
Pf6N2E2_1434 +0.5 1.2 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) compare
Pf6N2E2_1343 +0.5 1.3 Transcriptional regulator compare
Pf6N2E2_342 +0.5 0.9 DNA-binding response regulator compare
Pf6N2E2_3228 +0.5 2.4 N-acetylneuraminic acid outer membrane channel protein NanC compare
Pf6N2E2_5748 +0.5 1.7 Transcriptional activator protein LuxR compare
Pf6N2E2_3035 +0.5 3.5 DNA mismatch repair protein MutS compare
Pf6N2E2_1440 +0.5 1.3 Putative tRNA-m1A22 methylase compare
Pf6N2E2_2111 +0.5 1.5 Dehydrocarnitine CoA-transferase and acetoacetate CoA-transferase, subunit A (from data) compare
Pf6N2E2_1437 +0.5 1.9 Acyl-CoA dehydrogenase family protein compare
Pf6N2E2_1383 +0.5 1.4 YD repeat protein compare
Pf6N2E2_3770 +0.5 1.2 ATP-dependent hsl protease ATP-binding subunit HslU compare
Pf6N2E2_2261 +0.5 2.7 VacJ-like lipoprotein precursor compare
Pf6N2E2_5761 +0.5 1.1 Transcriptional regulator, TetR family compare
Pf6N2E2_2003 +0.5 0.7 hypothetical protein compare
Pf6N2E2_2901 +0.5 2.5 Iron siderophore sensor protein compare
Pf6N2E2_469 +0.5 0.7 lipoprotein, putative compare
Pf6N2E2_3151 +0.5 1.1 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_6059 +0.5 1.5 FIG008443: hypothetical protein compare
Pf6N2E2_170 +0.5 1.0 lipoprotein, putative compare
Pf6N2E2_2254 +0.5 1.9 Cell filamentation protein fic compare
Pf6N2E2_6050 +0.5 1.8 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_100 +0.5 3.0 membrane protein, putative compare
Pf6N2E2_5988 +0.5 2.2 hypothetical protein compare
Pf6N2E2_5500 +0.5 1.3 MoxR-like ATPases compare
Pf6N2E2_37 +0.5 1.6 6-carboxytetrahydropterin synthase (EC 4.1.2.50) @ Queuosine biosynthesis QueD, PTPS-I compare
Pf6N2E2_1989 +0.5 1.1 hypothetical protein compare
Pf6N2E2_868 +0.5 0.8 Transcriptional regulator, HxlR family compare
Pf6N2E2_553 +0.5 1.9 Uncharacterized protein ImpD compare
Pf6N2E2_1481 +0.5 2.3 VgrG protein compare
Pf6N2E2_3725 +0.5 1.5 FIG085779: Lipoprotein compare
Pf6N2E2_4057 +0.5 0.6 lipoprotein, putative compare
Pf6N2E2_5232 +0.5 2.8 Cell division inhibitor compare
Pf6N2E2_5618 +0.5 3.0 Probable thiol oxidoreductase with 2 cytochrome c heme-binding sites compare
Pf6N2E2_330 +0.5 1.7 Mesenchymal stem cell protein DSCD75 compare
Pf6N2E2_2125 +0.5 1.4 hypothetical protein compare
Pf6N2E2_1824 +0.5 0.6 hypothetical protein compare
Pf6N2E2_3003 +0.5 1.3 Bacteriophage protein GP46 compare
Pf6N2E2_962 +0.5 0.7 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) compare
Pf6N2E2_1774 +0.5 0.8 DNA-binding response regulator, LuxR family, near polyamine transporter compare
Pf6N2E2_3634 +0.5 1.1 Transporter compare
Pf6N2E2_4300 +0.5 2.2 Uncharacterized protein similar to VCA0109 compare
Pf6N2E2_3714 +0.4 2.3 FIG017861: hypothetical protein compare
Pf6N2E2_861 +0.4 2.0 Transcriptional regulator, LysR family compare
Pf6N2E2_2314 +0.4 0.9 VapB protein (antitoxin to VapC) compare
Pf6N2E2_1870 +0.4 1.0 hypothetical protein compare
Pf6N2E2_1981 +0.4 2.3 FIG051360: Periplasmic protein TonB, links inner and outer membranes compare
Pf6N2E2_5782 +0.4 2.6 hypothetical protein compare
Pf6N2E2_1455 +0.4 2.1 Xylose ABC transporter, periplasmic xylose-binding protein XylF compare
Pf6N2E2_2402 +0.4 1.0 hypothetical protein compare
Pf6N2E2_68 +0.4 1.9 Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) compare
Pf6N2E2_1146 +0.4 2.3 2-methylbutanoyl-CoA dehydrogenase (EC 1.3.8.5) (from data) compare
Pf6N2E2_3864 +0.4 1.2 hypothetical protein compare
Pf6N2E2_3762 +0.4 2.2 NADP-dependent malic enzyme (EC 1.1.1.40) compare
Pf6N2E2_1185 +0.4 2.1 Acetylornithine deacetylase (EC 3.5.1.16) compare
Pf6N2E2_2988 +0.4 2.2 Putative NADPH-quinone reductase (modulator of drug activity B) compare
Pf6N2E2_1427 +0.4 1.6 6-aminohexanoate-dimer hydrolase (EC 3.5.1.46) compare
Pf6N2E2_1920 +0.4 1.1 Rubredoxin compare
Pf6N2E2_1879 +0.4 1.8 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) compare
Pf6N2E2_3180 +0.4 2.5 Type IV pilus biogenesis protein PilF compare
Pf6N2E2_3943 +0.4 2.4 COG3332 compare
Pf6N2E2_763 +0.4 1.9 Sigma-54 dependent transcriptional regulator compare
Pf6N2E2_368 +0.4 1.7 Succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16) compare
Pf6N2E2_1124 +0.4 0.9 Ferric siderophore transport system, periplasmic binding protein TonB compare


Specific Phenotypes

For 5 genes in this experiment

For stress D-Cycloserine in Pseudomonas fluorescens FW300-N2E2

For stress D-Cycloserine across organisms