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Experiment set3IT053 for
Methanococcus maripaludis JJ
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formate McAA pantothenate dropout
200 most important genes:
gene
name
fitness
t score
description
MMJJ
_RS00235
-6.8
-21.8
hypothetical protein
compare
MMJJ
_RS05450
-5.1
-20.5
TIGR03576 family pyridoxal phosphate-dependent enzyme
compare
MMJJ
_RS04200
-5.0
-8.3
triphosphoribosyl-dephospho-CoA synthase
compare
MMJJ
_RS05935
-4.7
-4.0
Era-like GTP-binding protein
compare
MMJJ
_RS05930
-4.5
-2.9
cell division protein SepF
compare
MMJJ
_RS08320
-4.4
-3.9
CDP-diacylglycerol--serine O-phosphatidyltransferase
compare
MMJJ
_RS06875
-4.3
-4.4
hypothetical protein
compare
MMJJ
_RS06625
-4.3
-3.4
pyruvate synthase subunit PorB
compare
MMJJ
_RS07665
-4.3
-23.6
formate dehydrogenase subunit alpha
compare
MMJJ
_RS05490
-4.3
-2.9
imidazole glycerol phosphate synthase subunit HisF
compare
MMJJ
_RS06490
-4.3
-4.1
methanogenesis marker 2 protein
compare
MMJJ
_RS07705
-4.2
-4.0
GTP-binding protein EngB
compare
MMJJ
_RS07950
-4.2
-4.9
4Fe-4S binding protein
compare
MMJJ
_RS06240
-4.1
-4.3
dihydropteroate synthase-like protein
compare
MMJJ
_RS06695
-4.1
-4.8
amidohydrolase
compare
MMJJ
_RS03895
-4.0
-5.0
hydrogenase expression/formation protein HypE
compare
MMJJ
_RS03580
-4.0
-5.4
TIGR00303 family protein
compare
MMJJ
_RS05070
-4.0
-3.3
DNA primase catalytic subunit PriS
compare
MMJJ
_RS02090
-4.0
-7.2
tyramine--L-glutamate ligase
compare
MMJJ
_RS07670
-4.0
-18.1
Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain
compare
MMJJ
_RS00275
-3.9
-4.2
coenzyme F420-0:L-glutamate ligase
compare
MMJJ
_RS03820
-3.8
-5.2
hydrogenase formation protein HypD
compare
MMJJ
_RS06725
-3.8
-15.0
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMJJ
_RS07000
-3.7
-2.6
TrkH family potassium uptake protein
compare
MMJJ
_RS04970
-3.7
-2.8
DUF655 domain-containing protein
compare
MMJJ
_RS03200
-3.7
-3.2
uroporphyrinogen-III synthase
compare
MMJJ
_RS06390
-3.7
-3.4
NADPH-dependent F420 reductase
compare
MMJJ
_RS04520
-3.6
-7.5
coenzyme F430 synthase
compare
MMJJ
_RS06040
-3.6
-4.8
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS08795
-3.6
-4.1
phosphoglucosamine mutase
compare
MMJJ
_RS02045
-3.5
-3.7
molybdenum cofactor guanylyltransferase
compare
MMJJ
_RS05330
-3.5
-3.4
DNA polymerase II large subunit
compare
MMJJ
_RS08020
-3.5
-10.5
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS04685
-3.5
-12.1
carbamoyltransferase HypF
compare
MMJJ
_RS05950
-3.5
-5.2
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
compare
MMJJ
_RS01360
-3.5
-3.3
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMJJ
_RS05535
-3.5
-13.4
hypothetical protein
compare
MMJJ
_RS03840
-3.4
-5.2
DHH family phosphoesterase
compare
MMJJ
_RS08625
-3.4
-8.5
magnesium/cobalt transporter CorA
compare
MMJJ
_RS01870
-3.4
-2.8
methanogenesis marker 15 protein
compare
MMJJ
_RS04475
-3.4
-6.2
3,4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMJJ
_RS07655
-3.4
-16.0
hypothetical protein
compare
MMJJ
_RS04995
-3.4
-6.8
Tfx family DNA-binding protein
compare
MMJJ
_RS05445
-3.4
-3.2
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
MMJJ
_RS04485
-3.4
-9.5
riboflavin synthase
compare
MMJJ
_RS03785
-3.3
-3.9
hypothetical protein
compare
MMJJ
_RS03760
-3.3
-5.0
hydrogenase maturation nickel metallochaperone HypA
compare
MMJJ
_RS03095
-3.3
-3.6
bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase
compare
MMJJ
_RS06855
-3.3
-2.9
DUF2104 domain-containing protein
compare
MMJJ
_RS03865
-3.3
-2.3
phosphoribosyl-AMP cyclohydrolase
compare
MMJJ
_RS01935
-3.3
-5.5
O-phosphoseryl-tRNA(Sec) selenium transferase
compare
MMJJ
_RS07945
-3.3
-4.8
4Fe-4S binding protein
compare
MMJJ
_RS07360
-3.3
-2.2
TIGR00269 family protein
compare
MMJJ
_RS00450
-3.2
-2.4
DUF126 domain-containing protein
compare
MMJJ
_RS07660
-3.2
-10.4
carbonic anhydrase
compare
MMJJ
_RS01600
-3.2
-3.6
radical SAM protein
compare
MMJJ
_RS06915
-3.2
-15.3
helix-turn-helix domain-containing protein
compare
MMJJ
_RS06375
-3.2
-5.2
UbiX family flavin prenyltransferase
compare
MMJJ
_RS03815
-3.2
-3.0
nascent polypeptide-associated complex protein
compare
MMJJ
_RS03615
-3.1
-4.5
cobalt-precorrin-8 methylmutase
compare
MMJJ
_RS01755
-3.1
-3.3
ferrous iron transport protein B
compare
MMJJ
_RS08250
-3.1
-6.7
hydrogenase maturation peptidase HycI
compare
MMJJ
_RS09190
-3.1
-2.5
tryptophan synthase subunit beta
compare
MMJJ
_RS01750
-3.1
-3.3
ferrous iron transport protein A
compare
MMJJ
_RS03065
-3.1
-13.0
CBS domain-containing protein
compare
MMJJ
_RS01810
-3.1
-2.1
methyl coenzyme M reductase system, component A2
compare
MMJJ
_RS08055
-3.1
-9.3
methanogenesis marker 14 protein
compare
MMJJ
_RS07190
-3.1
-5.7
RtcB family protein
compare
MMJJ
_RS01355
-3.0
-4.5
UDP-N-acetyl-D-mannosamine dehydrogenase
compare
MMJJ
_RS06805
-3.0
-3.5
monovalent cation/H+ antiporter subunit E
compare
MMJJ
_RS05610
-3.0
-6.3
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMJJ
_RS03875
-3.0
-5.0
CBS domain-containing protein
compare
MMJJ
_RS05650
-3.0
-3.6
formylmethanofuran dehydrogenase subunit B
compare
MMJJ
_RS06860
-3.0
-4.1
hypothetical protein
compare
MMJJ
_RS00215
-3.0
-3.3
CCA tRNA nucleotidyltransferase
compare
MMJJ
_RS05590
-3.0
-3.3
homoserine dehydrogenase
compare
MMJJ
_RS03125
-3.0
-5.3
GMC oxidoreductase
compare
MMJJ
_RS04800
-3.0
-6.6
2-phospho-L-lactate guanylyltransferase
compare
MMJJ
_RS03620
-2.9
-6.6
DUF2097 domain-containing protein
compare
MMJJ
_RS06180
-2.9
-3.4
tryptophan--tRNA ligase
compare
MMJJ
_RS03295
-2.9
-15.6
PHP domain-containing protein
compare
MMJJ
_RS08005
-2.9
-16.2
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMJJ
_RS04790
-2.9
-5.6
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMJJ
_RS03670
-2.9
-6.1
precorrin-2 C(20)-methyltransferase
compare
MMJJ
_RS06255
-2.9
-8.1
tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3
compare
MMJJ
_RS00070
-2.9
-4.0
CooT family nickel-binding protein
compare
MMJJ
_RS05575
-2.9
-4.9
2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase
compare
MMJJ
_RS06910
-2.9
-3.1
energy-converting NiFe hydrogenase A subunit EhaA
compare
MMJJ
_RS08660
-2.8
-4.6
acetylornithine transaminase
compare
MMJJ
_RS01415
-2.8
-3.0
beta-CASP ribonuclease aCPSF1
compare
MMJJ
_RS04675
-2.8
-6.9
thiamine pyrophosphate-binding protein
compare
MMJJ
_RS05260
-2.8
-5.6
ATP-grasp domain-containing protein
compare
MMJJ
_RS08095
-2.8
-5.0
cobyric acid synthase CobQ
compare
MMJJ
_RS01565
-2.8
-7.4
TIGR00267 family protein
compare
MMJJ
_RS03060
-2.8
-3.8
methanogenesis marker 7 protein
compare
MMJJ
_RS08620
-2.8
-4.0
DUF373 family protein
compare
MMJJ
_RS07410
-2.8
-4.8
methanogenesis marker protein Mmp4/MtxX
compare
MMJJ
_RS05620
-2.8
-6.0
CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein
compare
MMJJ
_RS07470
-2.8
-2.6
50S ribosome-binding GTPase
compare
MMJJ
_RS07380
-2.8
-9.1
sulfide-dependent adenosine diphosphate thiazole synthase
compare
MMJJ
_RS05655
-2.7
-7.7
HisA/HisF family protein
compare
MMJJ
_RS06785
-2.7
-7.9
RNA ligase partner protein
compare
MMJJ
_RS08000
-2.7
-9.8
HesA/MoeB/ThiF family protein
compare
MMJJ
_RS03110
-2.7
-4.5
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase
compare
MMJJ
_RS02920
-2.7
-2.9
30S ribosomal protein S27ae
compare
MMJJ
_RS06750
-2.7
-2.5
homoaconitase large subunit
compare
MMJJ
_RS05225
-2.7
-2.2
Gar1/Naf1 family protein
compare
MMJJ
_RS02935
-2.7
-3.3
DNA-directed RNA polymerase subunit E''
compare
MMJJ
_RS01865
-2.7
-6.3
peptidyl-tRNA hydrolase Pth2
compare
MMJJ
_RS04155
-2.6
-7.0
hypothetical protein
compare
MMJJ
_RS02275
-2.6
-5.1
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS01880
-2.6
-3.6
RlmE family RNA methyltransferase
compare
MMJJ
_RS04730
-2.6
-3.3
tyrosine decarboxylase MfnA
compare
MMJJ
_RS07350
-2.6
-3.8
4Fe-4S binding protein
compare
MMJJ
_RS04655
-2.6
-5.9
FAD-dependent oxidoreductase
compare
MMJJ
_RS09375
-2.6
-2.0
hypothetical protein
compare
MMJJ
_RS06840
-2.6
-3.7
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS00355
-2.6
-2.7
ribonuclease P protein component 4
compare
MMJJ
_RS08080
-2.6
-8.3
TIGR00300 family protein
compare
MMJJ
_RS03800
-2.6
-11.6
aldolase
compare
MMJJ
_RS06250
-2.5
-3.1
nicotinamide-nucleotide adenylyltransferase
compare
MMJJ
_RS06485
-2.5
-3.8
phosphoglycerate kinase
compare
MMJJ
_RS00570
-2.5
-2.3
ribonuclease P
compare
MMJJ
_RS08855
-2.5
-4.7
cyclic pyranopterin monophosphate synthase MoaC
compare
MMJJ
_RS03830
-2.5
-8.5
CBS domain-containing protein
compare
MMJJ
_RS06510
-2.5
-2.8
LL-diaminopimelate aminotransferase
compare
MMJJ
_RS05190
-2.5
-8.4
gamma carbonic anhydrase family protein
compare
MMJJ
_RS07245
-2.4
-5.0
amidohydrolase family protein
compare
MMJJ
_RS08340
-2.4
-4.2
archaeoflavoprotein AfpA
compare
MMJJ
_RS00270
-2.4
-5.0
adenosylcobinamide-GDP ribazoletransferase
compare
MMJJ
_RS06760
-2.4
-5.5
Ni-sirohydrochlorin a,c-diamide synthase
compare
MMJJ
_RS00050
-2.4
-9.9
AAA family ATPase
compare
MMJJ
_RS01690
-2.4
-4.2
methanogenesis marker 12 protein
compare
MMJJ
_RS06225
-2.4
-2.5
adenosylmethionine decarboxylase
compare
MMJJ
_RS01345
-2.4
-5.5
(5-formylfuran-3-yl)methyl phosphate synthase
compare
MMJJ
_RS00520
-2.4
-6.1
PDGLE domain-containing protein
compare
MMJJ
_RS06185
-2.4
-6.1
cobalamin biosynthesis protein
compare
MMJJ
_RS03055
-2.4
-3.1
hypothetical protein
compare
MMJJ
_RS06835
-2.4
-11.3
4Fe-4S binding protein
compare
MMJJ
_RS07640
-2.4
-17.5
cache domain-containing protein
compare
MMJJ
_RS03660
-2.4
-3.4
DUF447 family protein
compare
MMJJ
_RS03190
-2.4
-3.5
phosphopyruvate hydratase
compare
MMJJ
_RS03150
-2.4
-7.1
2-phospho-L-lactate transferase
compare
MMJJ
_RS07650
-2.3
-16.3
formate/nitrite transporter family protein
compare
MMJJ
_RS00580
-2.3
-1.5
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG
compare
MMJJ
_RS05810
-2.3
-7.3
precorrin-4 C(11)-methyltransferase
compare
MMJJ
_RS06155
-2.3
-5.6
phosphatidylglycerophosphatase A
compare
MMJJ
_RS07635
-2.3
-11.1
response regulator transcription factor
compare
MMJJ
_RS03630
-2.3
-10.5
AMP phosphorylase
compare
MMJJ
_RS06220
-2.2
-6.0
polyamine aminopropyltransferase
compare
MMJJ
_RS08065
-2.2
-3.3
precorrin-6Y C5,15-methyltransferase (decarboxylating) subunit CbiT
compare
MMJJ
_RS03270
-2.2
-1.8
ribosome biogenesis/translation initiation ATPase RLI
compare
MMJJ
_RS00265
-2.2
-8.4
TIGR02253 family HAD-type hydrolase
compare
MMJJ
_RS00035
-2.2
-14.2
CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
compare
MMJJ
_RS00210
-2.2
-2.7
DUF530 family protein
compare
MMJJ
_RS07355
-2.1
-5.2
MoaD/ThiS family protein
compare
MMJJ
_RS07720
-2.1
-2.8
UPF0058 family protein
compare
MMJJ
_RS05375
-2.1
-14.2
radical SAM protein
compare
MMJJ
_RS00205
-2.1
-4.7
adenosylcobinamide-phosphate synthase CbiB
compare
MMJJ
_RS00060
-2.1
-14.3
acetyl-CoA decarbonylase/synthase complex subunit gamma
compare
MMJJ
_RS04010
-2.1
-8.2
archaeal proteasome endopeptidase complex subunit alpha
compare
MMJJ
_RS05720
-2.1
-3.7
glutamine--fructose-6-phosphate transaminase (isomerizing)
compare
MMJJ
_RS00055
-2.1
-9.7
CO dehydrogenase/acetyl-CoA synthase subunit delta
compare
MMJJ
_RS08330
-2.1
-2.8
SufD family Fe-S cluster assembly protein
compare
MMJJ
_RS06700
-2.1
-4.2
L-seryl-tRNA(Sec) kinase
compare
MMJJ
_RS06010
-2.1
-5.1
hypothetical protein
compare
MMJJ
_RS00530
-2.0
-10.1
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS00080
-2.0
-12.2
DUF166 domain-containing protein
compare
MMJJ
_RS08840
-2.0
-4.6
calcium/sodium antiporter
compare
MMJJ
_RS00075
-2.0
-10.1
AAA family ATPase
compare
MMJJ
_RS06730
-2.0
-5.1
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS00045
-2.0
-11.6
CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
compare
MMJJ
_RS00065
-2.0
-9.6
4Fe-4S dicluster domain-containing protein
compare
MMJJ
_RS04620
-2.0
-2.7
homocitrate synthase family protein
compare
MMJJ
_RS06930
-2.0
-2.6
type II methionyl aminopeptidase
compare
MMJJ
_RS07155
-2.0
-8.8
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMJJ
_RS07725
-2.0
-5.1
DNA primase DnaG
compare
MMJJ
_RS06865
-2.0
-2.8
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS05295
-2.0
-7.8
cobyrinic acid a,c-diamide synthase
compare
MMJJ
_RS05155
-2.0
-5.4
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH
compare
MMJJ
_RS01830
-2.0
-2.6
tRNA(Ile)(2)-agmatinylcytidine synthase
compare
MMJJ
_RS00040
-2.0
-8.5
CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
compare
MMJJ
_RS06705
-2.0
-4.8
bifunctional NADP phosphatase/NAD kinase
compare
MMJJ
_RS08035
-2.0
-7.3
cobalt-precorrin-7 (C(5))-methyltransferase
compare
MMJJ
_RS06215
-2.0
-4.5
agmatinase
compare
MMJJ
_RS06050
-2.0
-10.9
molybdopterin molybdotransferase MoeA
compare
MMJJ
_RS08480
-1.9
-7.9
hydroxyethylthiazole kinase
compare
MMJJ
_RS04595
-1.9
-4.5
hypothetical protein
compare
MMJJ
_RS06015
-1.9
-9.4
Na(+)/H(+) antiporter subunit B
compare
MMJJ
_RS00125
-1.9
-2.6
KEOPS complex subunit Cgi121
compare
MMJJ
_RS04975
-1.9
-2.7
glycosyltransferase family 4 protein
compare
MMJJ
_RS07995
-1.9
-6.7
molybdenum cofactor biosynthesis protein MoaE
compare
MMJJ
_RS08535
-1.9
-3.5
NOL1/NOP2/sun family putative RNA methylase
compare
MMJJ
_RS02040
-1.9
-1.9
Asp-tRNA(Asn) amidotransferase subunit GatC
compare
MMJJ
_RS02055
-1.9
-9.7
GTP 3',8-cyclase MoaA
compare
MMJJ
_RS03500
-1.9
-10.1
F420-dependent methylenetetrahydromethanopterin dehydrogenase
compare
MMJJ
_RS00195
-1.9
-3.0
precorrin-3B C(17)-methyltransferase
compare
MMJJ
_RS04150
-1.8
-3.3
DUF5379 domain-containing protein
compare
MMJJ
_RS05540
-1.8
-13.9
LysR family transcriptional regulator
compare
MMJJ
_RS00645
-1.8
-10.9
adenosylmethionine--8-amino-7-oxononanoate transaminase
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments