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Experiment set3IT053 for
Methanococcus maripaludis JJ
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formate McAA pantothenate dropout
200 most detrimental genes:
gene
name
fitness
t score
description
MMJJ
_RS04415
+2.7
8.8
hypothetical protein
compare
MMJJ
_RS05280
+1.0
1.1
hypothetical protein
compare
MMJJ
_RS07015
+0.8
1.4
PFL family protein
compare
MMJJ
_RS04005
+0.7
5.3
acetate--CoA ligase family protein
compare
MMJJ
_RS07025
+0.7
3.9
tRNA (cytidine(56)-2'-O)-methyltransferase
compare
MMJJ
_RS01405
+0.6
0.5
proline--tRNA ligase
compare
MMJJ
_RS06495
+0.6
1.9
hypothetical protein
compare
MMJJ
_RS03725
+0.6
2.1
sulfurtransferase TusA family protein
compare
MMJJ
_RS07235
+0.6
5.1
coenzyme F420 hydrogenase subunit alpha
compare
MMJJ
_RS09120
+0.6
1.3
aspartate kinase
compare
MMJJ
_RS07825
+0.6
3.7
YciI family protein
compare
MMJJ
_RS05685
+0.6
4.1
class III signal peptide-containing protein
compare
MMJJ
_RS07240
+0.6
5.0
MBL fold metallo-hydrolase
compare
MMJJ
_RS07220
+0.6
4.5
coenzyme F420 hydrogenase subunit beta
compare
MMJJ
_RS04545
+0.5
2.4
PadR family transcriptional regulator
compare
MMJJ
_RS07225
+0.5
4.0
coenzyme F420 hydrogenase subunit gamma
compare
MMJJ
_RS03835
+0.5
1.9
DUF504 domain-containing protein
compare
MMJJ
_RS04955
+0.5
3.4
tRNA pseudouridine(54/55) synthase Pus10
compare
MMJJ
_RS08525
+0.5
2.8
peptidylprolyl isomerase
compare
MMJJ
_RS07920
+0.5
3.4
6-carboxytetrahydropterin synthase QueD
compare
MMJJ
_RS06210
+0.5
2.6
hypothetical protein
compare
MMJJ
_RS05915
+0.5
2.0
multiprotein bridging factor aMBF1
compare
MMJJ
_RS05525
+0.5
3.4
GTP-binding protein
compare
MMJJ
_RS05040
+0.5
3.8
7-carboxy-7-deazaguanine synthase QueE
compare
MMJJ
_RS03070
+0.4
1.5
MetS family NSS transporter small subunit
compare
MMJJ
_RS01855
+0.4
3.4
MBL fold metallo-hydrolase
compare
MMJJ
_RS06090
+0.4
2.5
hypothetical protein
compare
MMJJ
_RS08410
+0.4
1.5
CBS domain-containing protein
compare
MMJJ
_RS06085
+0.4
2.1
proteasome assembly chaperone family protein
compare
MMJJ
_RS01825
+0.4
2.5
DNA repair and recombination protein RadB
compare
MMJJ
_RS06275
+0.4
2.0
hypothetical protein
compare
MMJJ
_RS01150
+0.4
1.2
hypothetical protein
compare
MMJJ
_RS06675
+0.4
3.2
TIGR01212 family radical SAM protein
compare
MMJJ
_RS06580
+0.4
3.1
alanine dehydrogenase
compare
MMJJ
_RS06540
+0.4
1.6
DUF2120 domain-containing protein
compare
MMJJ
_RS06190
+0.4
3.2
7-cyano-7-deazaguanine synthase
compare
MMJJ
_RS04105
+0.4
3.4
prepilin peptidase
compare
MMJJ
_RS07260
+0.4
2.5
PspC domain-containing protein
compare
MMJJ
_RS06735
+0.4
2.6
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS05410
+0.4
2.1
RecB-family nuclease
compare
MMJJ
_RS06800
+0.4
2.0
prefoldin subunit alpha
compare
MMJJ
_RS07010
+0.4
2.1
preprotein translocase subunit Sec61beta
compare
MMJJ
_RS06640
+0.4
2.5
YfcE family phosphodiesterase
compare
MMJJ
_RS06950
+0.4
2.5
4-demethylwyosine synthase TYW1
compare
MMJJ
_RS06440
+0.4
2.2
DUF4870 domain-containing protein
compare
MMJJ
_RS04345
+0.4
1.2
DUF2080 family transposase-associated protein
compare
MMJJ
_RS06810
+0.4
2.9
L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha
compare
MMJJ
_RS06585
+0.4
2.0
alanine racemase
compare
MMJJ
_RS05980
+0.4
2.5
DUF5400 domain-containing protein
compare
MMJJ
_RS06205
+0.3
2.7
EamA family transporter
compare
MMJJ
_RS06500
+0.3
2.2
class I SAM-dependent methyltransferase
compare
MMJJ
_RS05975
+0.3
2.3
sulfurtransferase TusA family protein
compare
MMJJ
_RS06710
+0.3
2.8
TldD/PmbA family protein
compare
MMJJ
_RS06535
+0.3
2.9
UPF0104 family protein
compare
MMJJ
_RS08515
+0.3
1.3
secondary thiamine-phosphate synthase enzyme YjbQ
compare
MMJJ
_RS03250
+0.3
1.2
DUF2116 family Zn-ribbon domain-containing protein
compare
MMJJ
_RS09360
+0.3
2.2
hypothetical protein
compare
MMJJ
_RS06960
+0.3
2.8
CAP domain-containing protein
compare
MMJJ
_RS06280
+0.3
2.2
hypothetical protein
compare
MMJJ
_RS06680
+0.3
1.9
DUF366 family protein
compare
MMJJ
_RS06120
+0.3
2.3
DUF4013 domain-containing protein
compare
MMJJ
_RS08455
+0.3
1.8
tetratricopeptide repeat protein
compare
MMJJ
_RS07230
+0.3
2.0
coenzyme F420-reducing hydrogenase, FrhD protein
compare
MMJJ
_RS06515
+0.3
2.5
ribonuclease III
compare
MMJJ
_RS07495
+0.3
2.2
4Fe-4S binding protein
compare
MMJJ
_RS03905
+0.3
1.7
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS07915
+0.3
2.0
CBS domain-containing protein
compare
MMJJ
_RS07210
+0.3
2.4
AmmeMemoRadiSam system protein B
compare
MMJJ
_RS07270
+0.3
2.2
ribonuclease HII
compare
MMJJ
_RS07795
+0.3
1.6
cupin domain-containing protein
compare
MMJJ
_RS06790
+0.3
2.3
nucleotidyltransferase family protein
compare
MMJJ
_RS06685
+0.3
2.5
S-layer protein
compare
MMJJ
_RS03375
+0.3
1.3
hypothetical protein
compare
MMJJ
_RS05700
+0.3
2.0
metallophosphoesterase
compare
MMJJ
_RS05510
+0.3
2.1
archaellum operon transcriptional activator EarA family protein
compare
MMJJ
_RS06100
+0.3
1.9
rubrerythrin
compare
MMJJ
_RS06770
+0.3
2.3
hypothetical protein
compare
MMJJ
_RS01010
+0.3
2.6
right-handed parallel beta-helix repeat-containing protein
compare
MMJJ
_RS08830
+0.3
1.0
hypothetical protein
compare
MMJJ
_RS04500
+0.3
1.9
hypothetical protein
compare
MMJJ
_RS06080
+0.3
2.0
serine/threonine protein kinase
compare
MMJJ
_RS05500
+0.3
2.4
hypothetical protein
compare
MMJJ
_RS07185
+0.3
1.1
DUF371 domain-containing protein
compare
MMJJ
_RS07610
+0.3
1.9
DUF2119 domain-containing protein
compare
MMJJ
_RS09050
+0.3
1.2
hypothetical protein
compare
MMJJ
_RS06470
+0.3
2.1
tripartite tricarboxylate transporter permease
compare
MMJJ
_RS05580
+0.3
1.6
methanogenesis marker 9 domain-containing protein
compare
MMJJ
_RS04215
+0.3
2.1
DMT family transporter
compare
MMJJ
_RS00500
+0.3
1.2
GNAT family N-acetyltransferase
compare
MMJJ
_RS07445
+0.3
2.0
RlmF-related methyltransferase
compare
MMJJ
_RS04610
+0.2
1.0
ribosome assembly RNA-binding protein YhbY
compare
MMJJ
_RS08375
+0.2
1.9
ferritin
compare
MMJJ
_RS05960
+0.2
1.9
DUF169 domain-containing protein
compare
MMJJ
_RS06430
+0.2
1.5
haloacid dehalogenase
compare
MMJJ
_RS05115
+0.2
1.0
P-II family nitrogen regulator
compare
MMJJ
_RS07760
+0.2
1.4
GNAT family N-acetyltransferase
compare
MMJJ
_RS06745
+0.2
1.5
energy-coupling factor ABC transporter permease
compare
MMJJ
_RS08015
+0.2
1.2
HAD family hydrolase
compare
MMJJ
_RS06460
+0.2
1.5
cytochrome c
compare
MMJJ
_RS00395
+0.2
1.3
DUF473 domain-containing protein
compare
MMJJ
_RS07205
+0.2
1.3
MTH895/ArsE family thioredoxin-like protein
compare
MMJJ
_RS08705
+0.2
1.5
AEC family transporter
compare
MMJJ
_RS04375
+0.2
0.6
hypothetical protein
compare
MMJJ
_RS07365
+0.2
1.8
CatB-related O-acetyltransferase
compare
MMJJ
_RS05530
+0.2
1.0
roadblock/LC7 domain-containing protein
compare
MMJJ
_RS07680
+0.2
1.5
glucose-6-phosphate isomerase
compare
MMJJ
_RS07200
+0.2
1.9
MFS transporter
compare
MMJJ
_RS04965
+0.2
0.6
RNA polymerase Rpb4 family protein
compare
MMJJ
_RS06765
+0.2
1.8
hypothetical protein
compare
MMJJ
_RS01670
+0.2
0.9
hypothetical protein
compare
MMJJ
_RS07215
+0.2
1.8
TIGR00341 family protein
compare
MMJJ
_RS05605
+0.2
0.9
hypothetical protein
compare
MMJJ
_RS07695
+0.2
1.7
glycoside hydrolase family 15 protein
compare
MMJJ
_RS07765
+0.2
0.8
DMT family protein
compare
MMJJ
_RS07985
+0.2
1.1
hypothetical protein
compare
MMJJ
_RS08130
+0.2
0.2
translation initiation factor IF-2 subunit gamma
compare
MMJJ
_RS05690
+0.2
1.9
hypothetical protein
compare
MMJJ
_RS05900
+0.2
1.6
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS08745
+0.2
1.7
glycosyltransferase family 9 protein
compare
MMJJ
_RS03605
+0.2
0.9
TIGR00297 family protein
compare
MMJJ
_RS06235
+0.2
1.6
IGHMBP2 family helicase
compare
MMJJ
_RS03575
+0.2
1.1
NUDIX hydrolase
compare
MMJJ
_RS01790
+0.2
1.4
pyridoxamine 5'-phosphate oxidase family protein
compare
MMJJ
_RS01090
+0.2
1.3
hypothetical protein
compare
MMJJ
_RS06555
+0.2
1.3
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS08390
+0.2
0.8
carboxymuconolactone decarboxylase family protein
compare
MMJJ
_RS06450
+0.2
1.5
DUF3343 domain-containing protein
compare
MMJJ
_RS06550
+0.2
1.5
ABC transporter permease
compare
MMJJ
_RS09230
+0.2
0.8
hypothetical protein
compare
MMJJ
_RS03040
+0.2
1.4
lactate utilization protein
compare
MMJJ
_RS08180
+0.2
1.1
ABC transporter ATP-binding protein
compare
MMJJ
_RS03850
+0.2
0.8
nucleoside-diphosphate kinase
compare
MMJJ
_RS08400
+0.2
0.6
CoB--CoM heterodisulfide reductase subunit C
compare
MMJJ
_RS02265
+0.2
1.4
hypothetical protein
compare
MMJJ
_RS07890
+0.2
1.0
pyrimidine dimer DNA glycosylase/endonuclease V
compare
MMJJ
_RS07450
+0.2
0.8
hypothetical protein
compare
MMJJ
_RS04635
+0.2
1.1
DUF367 family protein
compare
MMJJ
_RS02160
+0.2
1.3
amino acid ABC transporter permease
compare
MMJJ
_RS00555
+0.2
1.1
hypothetical protein
compare
MMJJ
_RS08305
+0.2
1.0
peroxiredoxin
compare
MMJJ
_RS08370
+0.2
0.8
hypothetical protein
compare
MMJJ
_RS05660
+0.2
1.1
sulfopyruvate decarboxylase subunit beta
compare
MMJJ
_RS08100
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS03805
+0.2
0.7
hypothetical protein
compare
MMJJ
_RS09005
+0.2
1.6
N-6 DNA methylase
compare
MMJJ
_RS05990
+0.2
1.2
phosphatase PAP2 family protein
compare
MMJJ
_RS00845
+0.2
1.1
hypothetical protein
compare
MMJJ
_RS04915
+0.2
1.3
protein-L-isoaspartate O-methyltransferase
compare
MMJJ
_RS05355
+0.2
1.2
DUF2121 domain-containing protein
compare
MMJJ
_RS09205
+0.2
0.8
hypothetical protein
compare
MMJJ
_RS04525
+0.2
0.6
hypothetical protein
compare
MMJJ
_RS08165
+0.2
1.1
thermonuclease family protein
compare
MMJJ
_RS02180
+0.2
1.0
DHH family phosphoesterase
compare
MMJJ
_RS05340
+0.2
1.3
AAA family ATPase
compare
MMJJ
_RS00980
+0.2
1.2
flavodoxin family protein
compare
MMJJ
_RS01910
+0.2
1.4
class III signal peptide-containing protein
compare
MMJJ
_RS01250
+0.2
0.9
hypothetical protein
compare
MMJJ
_RS06045
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS07280
+0.2
1.0
phosphomannomutase/phosphoglucomutase
compare
MMJJ
_RS02270
+0.2
1.2
HEPN domain-containing protein
compare
MMJJ
_RS04135
+0.2
0.6
7-cyano-7-deazaguanine synthase QueC
compare
MMJJ
_RS00145
+0.2
1.2
aquaporin family protein
compare
MMJJ
_RS03730
+0.2
1.0
SWIM zinc finger family protein
compare
MMJJ
_RS07480
+0.2
1.4
FAD-dependent oxidoreductase
compare
MMJJ
_RS03775
+0.2
0.5
50S ribosomal protein L15e
compare
MMJJ
_RS02240
+0.2
0.9
CGGC domain-containing protein
compare
MMJJ
_RS03025
+0.2
1.4
Ig-like domain-containing protein
compare
MMJJ
_RS06505
+0.2
0.7
prephenate dehydratase
compare
MMJJ
_RS02285
+0.2
0.7
class III signal peptide-containing protein
compare
MMJJ
_RS07910
+0.2
1.1
CBS domain-containing protein
compare
MMJJ
_RS07905
+0.2
1.1
DUF89 domain-containing protein
compare
MMJJ
_RS06455
+0.2
1.2
YeeE/YedE family protein
compare
MMJJ
_RS08365
+0.2
1.1
DsrE family protein
compare
MMJJ
_RS02865
+0.2
1.0
amino acid ABC transporter substrate-binding protein
compare
MMJJ
_RS01300
+0.2
1.0
MarR family transcriptional regulator
compare
MMJJ
_RS06740
+0.2
0.8
energy-coupling factor ABC transporter substrate-binding protein
compare
MMJJ
_RS00960
+0.2
0.9
flavodoxin family protein
compare
MMJJ
_RS06135
+0.2
1.3
50S ribosomal protein L11 methyltransferase
compare
MMJJ
_RS01430
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS00150
+0.2
1.0
DUF2180 family protein
compare
MMJJ
_RS04580
+0.2
1.2
2-phosphosulfolactate phosphatase
compare
MMJJ
_RS07740
+0.2
1.1
DUF2334 domain-containing protein
compare
MMJJ
_RS04825
+0.1
1.3
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
compare
MMJJ
_RS05240
+0.1
1.3
type II secretion system F family protein
compare
MMJJ
_RS04870
+0.1
0.3
tRNA-Asp
compare
MMJJ
_RS05390
+0.1
1.2
tRNA pseudouridine(13) synthase TruD
compare
MMJJ
_RS04920
+0.1
0.9
CBS domain-containing protein
compare
MMJJ
_RS06445
+0.1
1.2
hypothetical protein
compare
MMJJ
_RS07855
+0.1
1.2
YkgJ family cysteine cluster protein
compare
MMJJ
_RS07815
+0.1
1.0
2-oxoacid:acceptor oxidoreductase family protein
compare
MMJJ
_RS02165
+0.1
1.0
ABC transporter substrate-binding protein
compare
MMJJ
_RS09065
+0.1
0.8
hypothetical protein
compare
MMJJ
_RS02355
+0.1
1.0
DUF2798 domain-containing protein
compare
MMJJ
_RS07385
+0.1
1.0
ribosomal protein S18-alanine N-acetyltransferase
compare
MMJJ
_RS05235
+0.1
1.2
Flp pilus assembly complex ATPase component TadA
compare
MMJJ
_RS08210
+0.1
1.4
hypothetical protein
compare
MMJJ
_RS07790
+0.1
1.0
hypothetical protein
compare
MMJJ
_RS07255
+0.1
1.2
hypothetical protein
compare
MMJJ
_RS02970
+0.1
1.1
DUF378 domain-containing protein
compare
MMJJ
_RS07835
+0.1
0.9
UPF0489 family protein
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments