Experiment set3IT052 for Caulobacter crescentus NA1000

Compare to:

PYE with Phosphomycin disodium salt 0.005 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
CCNA_00368 +8.9 59.3 phosphonates transport system permease protein phnE compare
CCNA_00366 +8.7 62.3 phosphonates transport ATP-binding protein phnC compare
CCNA_00367 +8.5 56.0 phosphonates-binding protein compare
CCNA_01219 +8.4 19.8 putative cytosolic protein compare
CCNA_03577 +7.8 30.8 DNA polymerase I compare
CCNA_01210 +7.7 26.8 nucleotidyltransferase family protein compare
CCNA_01449 +7.2 20.5 fructose-1,6-bisphosphatase, FIG superfamily compare
CCNA_01618 +6.5 23.8 uracil-DNA glycosylase compare
CCNA_02328 +6.4 3.1 cell cycle regulatory protein GcrA compare
CCNA_02941 +6.4 19.9 transcription elongation factor greA compare
CCNA_01141 +5.1 29.8 RecA protein compare
CCNA_01217 +4.8 16.6 phosphatidylglycerophosphate synthase compare
CCNA_01324 +4.6 20.2 LSU ribosomal protein L30P compare
CCNA_01250 +4.2 24.3 FecCD-family transporter protein compare
CCNA_01249 +4.1 20.8 ABC-transporter substrate binding protein compare
CCNA_01251 +4.1 15.2 FepC-type transporter protein compare
CCNA_00001 +4.0 6.2 ATP/GTP-binding protein compare
CCNA_00292 +3.9 3.4 phosphate transport system permease protein pstC compare
CCNA_02966 +3.9 13.0 non-specific DNA-binding protein Dps/iron-binding ferritin-like antioxidant protein/ferroxidase compare
CCNA_01918 +3.5 18.4 cyclic di-GMP effector protein PopA compare
CCNA_02090 +3.5 17.3 exodeoxyribonuclease III compare
CCNA_02545 +3.4 22.3 alkaline phosphatase compare
CCNA_00778 +3.4 15.6 GTP-binding protein TypA/BipA compare
CCNA_00781 +3.3 20.3 two-component receiver protein CpdR compare
CCNA_01123 +3.2 21.6 peptide chain release factor RF-3 compare
CCNA_01361 +3.2 6.6 PepSY superfamily protein compare
CCNA_03652 +3.1 20.1 ATP-dependent nuclease subunit A compare
CCNA_03651 +3.1 20.3 ATP-dependent nuclease subunit B compare
CCNA_03702 +3.1 1.5 SSU ribosomal protein S1P compare
CCNA_01826 +3.0 19.7 vitamin B12 receptor compare
CCNA_03476 +3.0 11.6 ribonuclease HI compare
CCNA_02171 +3.0 22.3 nucleoside permease nupC compare
CCNA_02458 +2.9 19.6 methylmalonyl-CoA mutase beta subunit compare
CCNA_03643 +2.9 5.4 succinate dehydrogenase membrane anchor subunit compare
CCNA_03352 +2.9 10.5 YebC/PmpR transcriptional regulator compare
CCNA_00766 +2.8 14.7 cobalamin adenosyltransferase family protein compare
CCNA_00284 +2.8 12.0 pyrimidine 5'-nucleotidase family protein compare
CCNA_03871 +2.7 7.9 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA compare
CCNA_02459 +2.6 19.8 methylmalonyl-CoA mutase alpha subunit compare
CCNA_02698 +2.6 16.6 Inosine-uridine nucleoside N-ribohydrolase compare
CCNA_01622 +2.5 11.1 Rsh ppGpp hydrolase-synthetase compare
CCNA_03404 +2.4 9.7 regulator of CtrA degradation RcdA compare
CCNA_01224 +2.3 6.8 O-antigen membrane transport protein compare
CCNA_01531 +2.3 12.3 acetyltransferase compare
CCNA_01010 +2.2 16.3 histidine ammonia-lyase compare
CCNA_01954 +2.1 4.2 ribonuclease E compare
CCNA_01430 +2.0 7.3 hypothetical protein compare
CCNA_02278 +2.0 11.9 hypothetical protein compare
CCNA_01447 +2.0 9.3 homoserine dehydrogenase compare
CCNA_00684 +2.0 9.1 anti-sigma factor, ChrR-family compare
CCNA_03762 +2.0 3.8 acetolactate synthase-related protein compare
CCNA_00280 +2.0 12.7 tRNA pseudouridine synthase A compare
CCNA_01237 +1.9 3.5 hypothetical protein compare
CCNA_01448 +1.9 5.3 fructose-1,6-bisphosphatase, class II compare
CCNA_01596 +1.8 4.7 DNA helicase II compare
CCNA_01739 +1.8 6.7 LSU ribosomal protein L9P compare
CCNA_03260 +1.8 6.9 queuosine biosynthesis protein QueD compare
CCNA_02012 +1.7 9.7 metal-dependent hydrolase compare
CCNA_00852 +1.7 8.6 TetR family transcriptional regulator compare
CCNA_03633 +1.7 3.1 GIY-YIG domain protein compare
CCNA_03384 +1.6 1.8 LSU ribosomal protein L31P compare
CCNA_03013 +1.6 9.1 alkyl hydroperoxide reductase subunit F compare
CCNA_01923 +1.6 8.6 ATP-dependent RNA helicase compare
CCNA_01405 +1.6 5.3 GIY-YIG domain protein compare
CCNA_03872 +1.5 4.6 tRNA (5-carboxymethylaminomethyl-2-thiouridylate) synthase compare
CCNA_01255 +1.5 2.2 hypothetical protein compare
CCNA_01517 +1.5 6.4 hypothetical protein compare
CCNA_R0026 +1.5 1.2 tRNA-Gly compare
CCNA_01942 +1.5 6.0 Rrf2 family protein compare
CCNA_01914 +1.5 8.8 16S rRNA m(2)G 1207 methyltransferase RsmC compare
CCNA_03528 +1.5 6.6 RNA methyltransferase compare
CCNA_01578 +1.5 7.7 beta-lactamase repressor compare
CCNA_03060 +1.5 1.8 hypothetical protein compare
CCNA_00857 +1.5 7.1 D-xylose transporter (from data) compare
CCNA_02847 +1.4 2.8 cytochrome c-type biogenesis protein ccmH compare
CCNA_00893 +1.4 3.8 helix-turn-helix DNA-binding protein compare
CCNA_01715 +1.4 4.9 GPH-family phosphatase compare
CCNA_00011 +1.4 6.3 chaperone protein DnaJ compare
CCNA_03150 +1.4 1.5 hypothetical protein compare
CCNA_03940 +1.4 2.1 hypothetical protein compare
CCNA_02845 +1.4 5.3 two-component response regulator compare
CCNA_01168 +1.4 1.9 3-ketoacyl-CoA thiolase compare
CCNA_00152 +1.4 7.1 winged helix-turn-helix transcription repressor HrcA compare
CCNA_02842 +1.4 7.2 two-component sensor histidine kinase compare
CCNA_00147 +1.4 1.5 hypothetical protein compare
CCNA_01561 +1.3 3.4 hypothetical protein compare
CCNA_02059 +1.3 4.8 ribosomal large subunit pseudouridine synthase C compare
CCNA_01546 +1.3 8.1 DEAD-box RNA helicase-like protein compare
CCNA_01851 +1.3 9.3 quinol cytochrome oxidase polypeptide II compare
CCNA_03156 +1.3 3.1 putative periplasmic protein compare
CCNA_02619 +1.3 9.6 stomatin/prohibitin-related protein compare
CCNA_02087 +1.3 8.3 deoxyguanosinetriphosphate triphosphohydrolase compare
CCNA_01011 +1.3 5.9 imidazolonepropionase compare
CCNA_00133 +1.3 7.0 radical SAM family enzyme compare
CCNA_03811 +1.3 6.9 LysR-family transcriptional regulator compare
CCNA_R0037 +1.3 2.4 tRNA-Glu compare
CCNA_00035 +1.3 6.6 tRNA pseudouridine synthase B compare
CCNA_00499 +1.3 4.7 hypothetical protein compare
CCNA_02702 +1.3 7.9 xanthine dehydrogenase small subunit compare
CCNA_03646 +1.3 7.0 ATPase compare
CCNA_02305 +1.3 6.5 chorismate mutase-family protein compare
CCNA_01765 +1.3 2.4 peptidase inhibitor, I78 family compare
CCNA_01193 +1.2 9.5 amylosucrase compare
CCNA_00807 +1.2 1.5 ribonuclease P protein component compare
CCNA_00824 +1.2 6.1 GntR-family transcriptional regulator compare
CCNA_00452 +1.2 7.0 N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25) (from data) compare
CCNA_03038 +1.2 7.4 pilus assembly ATPase CpaE compare
CCNA_01583 +1.2 1.8 phosphate-binding protein compare
CCNA_01732 +1.2 5.0 DNA repair protein RadA compare
CCNA_01603 +1.2 6.6 aspartate aminotransferase compare
CCNA_03039 +1.2 6.5 pilus assembly protein CpaD compare
CCNA_02396 +1.2 3.7 GST / metaxin-like protein compare
CCNA_00507 +1.2 3.6 cytochrome c1 compare
CCNA_01690 +1.2 2.6 MAPEG family membrane protein compare
CCNA_01850 +1.2 8.9 quinol cytochrome oxidase polypeptide I compare
CCNA_01216 +1.2 4.6 phosphohydrolase, Icc family compare
CCNA_01668 +1.2 5.2 sulfate transport system permease protein cysT compare
CCNA_02004 +1.2 2.1 SOS-induced inhibitor of cell division SidA compare
CCNA_00054 +1.1 5.7 tRNA 2-methylthioadenosine synthase compare
CCNA_01025 +1.1 6.2 hypothetical protein compare
CCNA_02760 +1.1 4.3 hypothetical protein compare
CCNA_02426 +1.1 4.6 ribonuclease, CafA family compare
CCNA_02279 +1.1 2.2 disulfide bond formation protein B compare
CCNA_00939 +1.1 4.4 MarR-family transcriptional regulator compare
CCNA_00257 +1.1 4.8 adenosylhomocysteinase compare
CCNA_00521 +1.1 2.3 antitoxin protein compare
CCNA_00971 +1.1 3.9 hydroxyacylglutathione hydrolase compare
CCNA_03212 +1.1 2.6 hypothetical protein compare
CCNA_00245 +1.1 3.1 pterin-4-alpha-carbinolamine dehydratase compare
CCNA_01415 +1.1 6.6 methyltransferase compare
CCNA_00151 +1.1 5.1 ribonuclease PH compare
CCNA_01853 +1.1 3.0 hypothetical protein compare
CCNA_03070 +1.1 2.4 4-oxalocrotonate tautomerase compare
CCNA_03564 +1.1 2.6 PaaI-family thioesterase-like protein compare
CCNA_01014 +1.1 3.3 cysteinyl-tRNA(Pro) deacylase compare
CCNA_01635 +1.1 4.1 DNA repair protein recO compare
CCNA_00860 +1.1 3.0 holdfast inhibitor protein HfiA compare
CCNA_00811 +1.1 5.2 TetR-family transcriptional regulator compare
CCNA_03107 +1.1 3.5 cytidine deaminase compare
CCNA_00753 +1.1 5.0 lysine 2,3-aminomutase compare
CCNA_03041 +1.1 5.7 pilus assembly protein CpaB compare
CCNA_00392 +1.0 5.3 dihydroorotase compare
CCNA_01614 +1.0 1.0 hypothetical protein compare
CCNA_01006 +1.0 3.8 flagellar hook-basal body complex protein FliE compare
CCNA_00323 +1.0 4.9 low-affinity zinc transport protein compare
CCNA_00675 +1.0 3.6 VapC-like PIN domain ribonuclease compare
CCNA_02701 +1.0 6.5 xanthine dehydrogenase large subunit compare
CCNA_01226 +1.0 3.5 hypothetical protein compare
CCNA_01406 +1.0 4.8 metal-dependent hydrolase compare
CCNA_01801 +1.0 3.9 hypothetical protein compare
CCNA_03460 +1.0 3.1 hypothetical protein compare
CCNA_00944 +1.0 5.8 flagellar hook length determination protein compare
CCNA_02436 +1.0 3.2 hypothetical protein compare
CCNA_00454 +1.0 5.2 GntR-family transcriptional regulator compare
CCNA_02671 +1.0 1.8 hypothetical protein compare
CCNA_03753 +1.0 4.7 iron-sulfur cluster-binding protein compare
CCNA_02976 +1.0 3.7 MCP-signal associated domain protein compare
CCNA_02569 +1.0 4.5 glutathione S-transferase compare
CCNA_01728 +1.0 4.6 short chain dehydrogenase compare
CCNA_00344 +1.0 3.0 hypothetical protein compare
CCNA_03556 +1.0 3.5 multidrug efflux system protein compare
CCNA_00036 +1.0 1.6 ribosome-binding factor A compare
CCNA_02336 +1.0 3.3 lysophospholipase L2 compare
CCNA_R0047 +1.0 1.5 tRNA-Val compare
CCNA_00047 +1.0 5.1 tRNA m7-G46 methyltransferase compare
CCNA_02703 +1.0 2.3 5-hydroxyisourate hydrolase compare
CCNA_01714 +1.0 2.5 Spx/MgsR-related protein compare
CCNA_03044 +1.0 4.4 CpaC-related secretion pathway protein compare
CCNA_02679 +1.0 3.0 conserved transmembrane protein compare
CCNA_02475 +1.0 6.5 transcriptional regulator vanR compare
CCNA_01849 +1.0 5.5 quinol cytochrome oxidase polypeptide III compare
CCNA_03493 +1.0 2.1 ADP-ribose pyrophosphatase, nudix family compare
CCNA_01977 +1.0 2.2 1-acyl-sn-glycerol-3-phosphate acyltransferase compare
CCNA_02821 +1.0 4.1 hipA-related phosphatidylinositol 3/4-kinase compare
CCNA_01963 +1.0 3.4 hypothetical protein compare
CCNA_01245 +1.0 3.8 23S rRNA methyltransferase compare
CCNA_00447 +1.0 4.9 chemotaxis protein cheD compare
CCNA_01639 +0.9 2.5 beta-lactamase family protein compare
CCNA_02816 +0.9 1.1 hypothetical protein compare
CCNA_02590 +0.9 4.8 aldo-keto reductase family protein compare
CCNA_01013 +0.9 4.5 histidine utilization repressor compare
CCNA_00157 +0.9 2.1 glyoxalase family protein compare
CCNA_02696 +0.9 4.4 AtzE family amidohydrolase compare
CCNA_02152 +0.9 3.3 phosphoglycerate mutase compare
CCNA_01848 +0.9 4.9 quinol cytochrome oxidase polypeptide IV compare
CCNA_00845 +0.9 3.9 antitoxin protein relB-1 compare
CCNA_03037 +0.9 5.8 pilus assembly ATPase CpaF compare
CCNA_03158 +0.9 4.7 iron-sulfur cluster assembly/repair protein ApbE compare
CCNA_03155 +0.9 5.7 PepSY-associated transmembrane protein compare
CCNA_03924 +0.9 2.7 hypothetical protein compare
CCNA_03118 +0.9 1.4 hypothetical protein compare
CCNA_01949 +0.9 2.4 bactofilin A BacA compare
CCNA_00934 +0.9 3.5 hypothetical protein compare
CCNA_03954 +0.9 1.0 hypothetical protein compare
CCNA_02523 +0.9 4.2 hypothetical protein compare
CCNA_00947 +0.9 6.6 flagellar hook protein FlgE compare
CCNA_01847 +0.9 5.9 cytochrome c oxidase assembly protein Surf1 compare
CCNA_03275 +0.9 0.8 hypothetical protein compare
CCNA_02416 +0.9 4.4 DNA-binding protein HU compare
CCNA_03035 +0.9 5.2 TadC-related pilus assembly protein compare


Specific Phenotypes

For 2 genes in this experiment

For stress Phosphomycin disodium salt in Caulobacter crescentus NA1000

For stress Phosphomycin disodium salt across organisms