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Experiment set3IT051 for
Methanococcus maripaludis JJ
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formate McAA nicotinic acid dropout
200 most detrimental genes:
gene
name
fitness
t score
description
MMJJ
_RS04415
+2.9
11.7
hypothetical protein
compare
MMJJ
_RS07015
+0.9
1.4
PFL family protein
compare
MMJJ
_RS08130
+0.9
1.0
translation initiation factor IF-2 subunit gamma
compare
MMJJ
_RS08830
+0.9
4.0
hypothetical protein
compare
MMJJ
_RS04005
+0.8
6.0
acetate--CoA ligase family protein
compare
MMJJ
_RS07935
+0.8
0.8
protein fwdD
compare
MMJJ
_RS07230
+0.7
4.5
coenzyme F420-reducing hydrogenase, FrhD protein
compare
MMJJ
_RS05685
+0.6
4.3
class III signal peptide-containing protein
compare
MMJJ
_RS03835
+0.6
2.2
DUF504 domain-containing protein
compare
MMJJ
_RS07235
+0.6
4.6
coenzyme F420 hydrogenase subunit alpha
compare
MMJJ
_RS04545
+0.6
2.0
PadR family transcriptional regulator
compare
MMJJ
_RS07220
+0.6
4.3
coenzyme F420 hydrogenase subunit beta
compare
MMJJ
_RS06640
+0.5
3.8
YfcE family phosphodiesterase
compare
MMJJ
_RS06275
+0.5
2.7
hypothetical protein
compare
MMJJ
_RS06085
+0.5
2.4
proteasome assembly chaperone family protein
compare
MMJJ
_RS07025
+0.5
2.2
tRNA (cytidine(56)-2'-O)-methyltransferase
compare
MMJJ
_RS07225
+0.5
3.7
coenzyme F420 hydrogenase subunit gamma
compare
MMJJ
_RS07205
+0.5
3.1
MTH895/ArsE family thioredoxin-like protein
compare
MMJJ
_RS07750
+0.5
1.6
class III signal peptide-containing protein
compare
MMJJ
_RS04955
+0.5
3.2
tRNA pseudouridine(54/55) synthase Pus10
compare
MMJJ
_RS06680
+0.5
2.5
DUF366 family protein
compare
MMJJ
_RS06745
+0.5
3.1
energy-coupling factor ABC transporter permease
compare
MMJJ
_RS03725
+0.5
2.1
sulfurtransferase TusA family protein
compare
MMJJ
_RS06540
+0.5
1.3
DUF2120 domain-containing protein
compare
MMJJ
_RS06675
+0.5
3.8
TIGR01212 family radical SAM protein
compare
MMJJ
_RS07185
+0.5
1.2
DUF371 domain-containing protein
compare
MMJJ
_RS09295
+0.5
0.6
hypothetical protein
compare
MMJJ
_RS07240
+0.5
4.0
MBL fold metallo-hydrolase
compare
MMJJ
_RS07005
+0.5
2.1
transcription factor S
compare
MMJJ
_RS06460
+0.5
3.0
cytochrome c
compare
MMJJ
_RS07985
+0.5
1.8
hypothetical protein
compare
MMJJ
_RS06090
+0.4
2.6
hypothetical protein
compare
MMJJ
_RS08410
+0.4
1.7
CBS domain-containing protein
compare
MMJJ
_RS06950
+0.4
3.1
4-demethylwyosine synthase TYW1
compare
MMJJ
_RS06440
+0.4
3.3
DUF4870 domain-containing protein
compare
MMJJ
_RS06735
+0.4
3.2
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS08305
+0.4
2.3
peroxiredoxin
compare
MMJJ
_RS07765
+0.4
2.0
DMT family protein
compare
MMJJ
_RS06515
+0.4
3.2
ribonuclease III
compare
MMJJ
_RS05975
+0.4
2.5
sulfurtransferase TusA family protein
compare
MMJJ
_RS04850
+0.4
2.4
energy-coupling factor transporter transmembrane protein EcfT
compare
MMJJ
_RS06500
+0.4
2.6
class I SAM-dependent methyltransferase
compare
MMJJ
_RS06810
+0.4
2.9
L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha
compare
MMJJ
_RS04105
+0.4
3.1
prepilin peptidase
compare
MMJJ
_RS06740
+0.4
2.1
energy-coupling factor ABC transporter substrate-binding protein
compare
MMJJ
_RS07920
+0.4
2.5
6-carboxytetrahydropterin synthase QueD
compare
MMJJ
_RS06120
+0.4
2.6
DUF4013 domain-containing protein
compare
MMJJ
_RS07915
+0.4
2.3
CBS domain-containing protein
compare
MMJJ
_RS06550
+0.4
2.7
ABC transporter permease
compare
MMJJ
_RS09360
+0.4
2.5
hypothetical protein
compare
MMJJ
_RS06580
+0.4
2.6
alanine dehydrogenase
compare
MMJJ
_RS06470
+0.4
2.6
tripartite tricarboxylate transporter permease
compare
MMJJ
_RS03350
+0.4
0.5
hypothetical protein
compare
MMJJ
_RS07210
+0.4
2.7
AmmeMemoRadiSam system protein B
compare
MMJJ
_RS08100
+0.4
2.1
hypothetical protein
compare
MMJJ
_RS03375
+0.3
2.1
hypothetical protein
compare
MMJJ
_RS04965
+0.3
0.8
RNA polymerase Rpb4 family protein
compare
MMJJ
_RS00500
+0.3
1.2
GNAT family N-acetyltransferase
compare
MMJJ
_RS08365
+0.3
2.1
DsrE family protein
compare
MMJJ
_RS07260
+0.3
2.5
PspC domain-containing protein
compare
MMJJ
_RS05530
+0.3
1.5
roadblock/LC7 domain-containing protein
compare
MMJJ
_RS07795
+0.3
1.8
cupin domain-containing protein
compare
MMJJ
_RS06210
+0.3
1.6
hypothetical protein
compare
MMJJ
_RS06710
+0.3
2.8
TldD/PmbA family protein
compare
MMJJ
_RS06685
+0.3
2.9
S-layer protein
compare
MMJJ
_RS08485
+0.3
1.6
Lrp/AsnC family transcriptional regulator
compare
MMJJ
_RS03905
+0.3
1.6
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS06770
+0.3
2.7
hypothetical protein
compare
MMJJ
_RS06960
+0.3
2.9
CAP domain-containing protein
compare
MMJJ
_RS03250
+0.3
1.0
DUF2116 family Zn-ribbon domain-containing protein
compare
MMJJ
_RS06280
+0.3
2.4
hypothetical protein
compare
MMJJ
_RS07820
+0.3
2.1
bifunctional hexulose-6-phosphate synthase/ribonuclease regulator
compare
MMJJ
_RS06080
+0.3
2.3
serine/threonine protein kinase
compare
MMJJ
_RS06290
+0.3
1.9
DUF749 domain-containing protein
compare
MMJJ
_RS04375
+0.3
0.9
hypothetical protein
compare
MMJJ
_RS06765
+0.3
2.4
hypothetical protein
compare
MMJJ
_RS08515
+0.3
1.3
secondary thiamine-phosphate synthase enzyme YjbQ
compare
MMJJ
_RS07810
+0.3
2.1
3-methyl-2-oxobutanoate dehydrogenase subunit VorB
compare
MMJJ
_RS02270
+0.3
1.4
HEPN domain-containing protein
compare
MMJJ
_RS06190
+0.3
2.2
7-cyano-7-deazaguanine synthase
compare
MMJJ
_RS04225
+0.3
2.1
aldo/keto reductase
compare
MMJJ
_RS06535
+0.3
2.3
UPF0104 family protein
compare
MMJJ
_RS04635
+0.3
1.9
DUF367 family protein
compare
MMJJ
_RS06520
+0.3
2.0
TldD/PmbA family protein
compare
MMJJ
_RS07215
+0.3
2.3
TIGR00341 family protein
compare
MMJJ
_RS07815
+0.3
2.0
2-oxoacid:acceptor oxidoreductase family protein
compare
MMJJ
_RS07495
+0.3
1.5
4Fe-4S binding protein
compare
MMJJ
_RS03070
+0.3
1.3
MetS family NSS transporter small subunit
compare
MMJJ
_RS07480
+0.3
2.1
FAD-dependent oxidoreductase
compare
MMJJ
_RS09205
+0.3
1.0
hypothetical protein
compare
MMJJ
_RS05390
+0.3
2.0
tRNA pseudouridine(13) synthase TruD
compare
MMJJ
_RS02160
+0.3
1.7
amino acid ABC transporter permease
compare
MMJJ
_RS08685
+0.3
1.9
phosphate ABC transporter permease subunit PstC
compare
MMJJ
_RS00150
+0.3
1.5
DUF2180 family protein
compare
MMJJ
_RS07200
+0.3
2.0
MFS transporter
compare
MMJJ
_RS08225
+0.3
0.9
peptidylprolyl isomerase
compare
MMJJ
_RS07855
+0.3
1.9
YkgJ family cysteine cluster protein
compare
MMJJ
_RS07445
+0.3
1.8
RlmF-related methyltransferase
compare
MMJJ
_RS06495
+0.3
0.8
hypothetical protein
compare
MMJJ
_RS06590
+0.3
2.0
sodium:alanine symporter family protein
compare
MMJJ
_RS09065
+0.2
1.4
hypothetical protein
compare
MMJJ
_RS06800
+0.2
1.2
prefoldin subunit alpha
compare
MMJJ
_RS06385
+0.2
1.1
hypothetical protein
compare
MMJJ
_RS05410
+0.2
1.7
RecB-family nuclease
compare
MMJJ
_RS07800
+0.2
1.9
AMP-binding protein
compare
MMJJ
_RS06205
+0.2
1.7
EamA family transporter
compare
MMJJ
_RS08525
+0.2
1.0
peptidylprolyl isomerase
compare
MMJJ
_RS01790
+0.2
1.8
pyridoxamine 5'-phosphate oxidase family protein
compare
MMJJ
_RS07760
+0.2
1.4
GNAT family N-acetyltransferase
compare
MMJJ
_RS05355
+0.2
1.5
DUF2121 domain-containing protein
compare
MMJJ
_RS06505
+0.2
0.9
prephenate dehydratase
compare
MMJJ
_RS01210
+0.2
0.6
hypothetical protein
compare
MMJJ
_RS00785
+0.2
0.3
hypothetical protein
compare
MMJJ
_RS04345
+0.2
0.9
DUF2080 family transposase-associated protein
compare
MMJJ
_RS05705
+0.2
1.8
hypothetical protein
compare
MMJJ
_RS03575
+0.2
1.3
NUDIX hydrolase
compare
MMJJ
_RS08285
+0.2
1.7
class I SAM-dependent methyltransferase
compare
MMJJ
_RS07610
+0.2
1.3
DUF2119 domain-containing protein
compare
MMJJ
_RS06445
+0.2
2.0
hypothetical protein
compare
MMJJ
_RS06560
+0.2
1.7
site-2 protease family protein
compare
MMJJ
_RS07270
+0.2
1.4
ribonuclease HII
compare
MMJJ
_RS05690
+0.2
2.1
hypothetical protein
compare
MMJJ
_RS07450
+0.2
1.4
hypothetical protein
compare
MMJJ
_RS05500
+0.2
2.0
hypothetical protein
compare
MMJJ
_RS01825
+0.2
1.2
DNA repair and recombination protein RadB
compare
MMJJ
_RS05585
+0.2
1.7
hypothetical protein
compare
MMJJ
_RS05605
+0.2
1.1
hypothetical protein
compare
MMJJ
_RS07890
+0.2
1.2
pyrimidine dimer DNA glycosylase/endonuclease V
compare
MMJJ
_RS02285
+0.2
0.8
class III signal peptide-containing protein
compare
MMJJ
_RS06105
+0.2
1.5
DUF99 family protein
compare
MMJJ
_RS05580
+0.2
1.4
methanogenesis marker 9 domain-containing protein
compare
MMJJ
_RS05200
+0.2
1.7
TIGR04013 family B12-binding domain/radical SAM domain-containing protein
compare
MMJJ
_RS05700
+0.2
1.4
metallophosphoesterase
compare
MMJJ
_RS03730
+0.2
0.9
SWIM zinc finger family protein
compare
MMJJ
_RS06790
+0.2
1.7
nucleotidyltransferase family protein
compare
MMJJ
_RS01430
+0.2
1.4
hypothetical protein
compare
MMJJ
_RS00145
+0.2
1.6
aquaporin family protein
compare
MMJJ
_RS06585
+0.2
1.3
alanine racemase
compare
MMJJ
_RS08350
+0.2
1.8
heavy metal translocating P-type ATPase
compare
MMJJ
_RS09020
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS06430
+0.2
1.3
haloacid dehalogenase
compare
MMJJ
_RS04500
+0.2
1.4
hypothetical protein
compare
MMJJ
_RS03040
+0.2
1.4
lactate utilization protein
compare
MMJJ
_RS03220
+0.2
1.6
inosine/xanthosine triphosphatase
compare
MMJJ
_RS02355
+0.2
1.3
DUF2798 domain-containing protein
compare
MMJJ
_RS00875
+0.2
1.1
hydrogenase iron-sulfur subunit
compare
MMJJ
_RS06135
+0.2
1.5
50S ribosomal protein L11 methyltransferase
compare
MMJJ
_RS06555
+0.2
1.5
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS01670
+0.2
0.9
hypothetical protein
compare
MMJJ
_RS05990
+0.2
1.4
phosphatase PAP2 family protein
compare
MMJJ
_RS03445
+0.2
1.3
hypothetical protein
compare
MMJJ
_RS09300
+0.2
0.6
hypothetical protein
compare
MMJJ
_RS07740
+0.2
1.2
DUF2334 domain-containing protein
compare
MMJJ
_RS03290
+0.2
1.5
amidohydrolase
compare
MMJJ
_RS07365
+0.2
1.4
CatB-related O-acetyltransferase
compare
MMJJ
_RS01855
+0.2
1.4
MBL fold metallo-hydrolase
compare
MMJJ
_RS01275
+0.2
0.7
4Fe-4S dicluster domain-containing protein
compare
MMJJ
_RS07255
+0.2
1.5
hypothetical protein
compare
MMJJ
_RS06235
+0.2
1.5
IGHMBP2 family helicase
compare
MMJJ
_RS04215
+0.2
1.4
DMT family transporter
compare
MMJJ
_RS07745
+0.2
1.4
DUF5814 domain-containing protein
compare
MMJJ
_RS08580
+0.2
0.8
YkgJ family cysteine cluster protein
compare
MMJJ
_RS00890
+0.2
1.3
coenzyme F420 hydrogenase subunit gamma
compare
MMJJ
_RS08045
+0.2
1.4
transporter substrate-binding domain-containing protein
compare
MMJJ
_RS08030
+0.2
1.3
hypothetical protein
compare
MMJJ
_RS05980
+0.2
1.1
DUF5400 domain-containing protein
compare
MMJJ
_RS06455
+0.2
1.2
YeeE/YedE family protein
compare
MMJJ
_RS07905
+0.2
1.1
DUF89 domain-containing protein
compare
MMJJ
_RS08310
+0.2
1.0
ZIP family metal transporter
compare
MMJJ
_RS01125
+0.2
0.7
hypothetical protein
compare
MMJJ
_RS07790
+0.2
1.3
hypothetical protein
compare
MMJJ
_RS07035
+0.2
0.2
glycosyl transferase
compare
MMJJ
_RS05660
+0.2
1.0
sulfopyruvate decarboxylase subunit beta
compare
MMJJ
_RS04420
+0.2
1.3
type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family
compare
MMJJ
_RS06045
+0.2
1.1
hypothetical protein
compare
MMJJ
_RS05965
+0.2
1.4
MFS transporter
compare
MMJJ
_RS08370
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS05405
+0.2
1.3
DNA cytosine methyltransferase
compare
MMJJ
_RS07280
+0.2
1.0
phosphomannomutase/phosphoglucomutase
compare
MMJJ
_RS06285
+0.2
1.1
YchF/TatD family DNA exonuclease
compare
MMJJ
_RS01745
+0.2
0.9
metal-dependent transcriptional regulator
compare
MMJJ
_RS01010
+0.2
1.5
right-handed parallel beta-helix repeat-containing protein
compare
MMJJ
_RS03450
+0.2
0.9
hypothetical protein
compare
MMJJ
_RS01970
+0.2
0.8
hypothetical protein
compare
MMJJ
_RS07835
+0.2
1.1
UPF0489 family protein
compare
MMJJ
_RS08195
+0.2
0.9
DUF4186 domain-containing protein
compare
MMJJ
_RS02880
+0.2
1.1
hypothetical protein
compare
MMJJ
_RS09120
+0.2
0.2
aspartate kinase
compare
MMJJ
_RS05235
+0.2
1.4
Flp pilus assembly complex ATPase component TadA
compare
MMJJ
_RS00405
+0.2
0.8
flavodoxin family protein
compare
MMJJ
_RS04825
+0.2
1.3
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
compare
MMJJ
_RS04815
+0.2
0.8
TIM barrel protein
compare
MMJJ
_RS07590
+0.2
1.0
flap endonuclease-1
compare
MMJJ
_RS04390
+0.2
1.2
rhomboid family intramembrane serine protease
compare
MMJJ
_RS06100
+0.2
1.0
rubrerythrin
compare
MMJJ
_RS09225
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS01795
+0.2
0.9
TIGR00266 family protein
compare
MMJJ
_RS02165
+0.2
1.1
ABC transporter substrate-binding protein
compare
MMJJ
_RS01845
+0.1
1.0
acetolactate decarboxylase
compare
MMJJ
_RS00860
+0.1
1.0
4Fe-4S binding protein
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments