Experiment set3IT050 for Pseudomonas fluorescens FW300-N2E2

Compare to:

LB with Cephalothin sodium salt 4 mg/ml

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_2129 -5.4 -5.2 Predicted dye-decolorizing peroxidase (DyP), YfeX-like subgroup compare
Pf6N2E2_5006 -4.3 -12.9 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_760 -4.1 -15.5 Na+/H+ antiporter NhaB compare
Pf6N2E2_2824 -3.8 -11.6 RND efflux system, inner membrane transporter CmeB compare
Pf6N2E2_2274 -3.7 -7.3 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_2823 -3.7 -6.0 Multidrug efflux RND membrane fusion protein MexC compare
Pf6N2E2_2753 -3.7 -4.9 HtrA protease/chaperone protein compare
Pf6N2E2_4803 -3.5 -2.4 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_5527 -3.3 -4.4 Cold shock protein CspC compare
Pf6N2E2_5430 -3.2 -12.9 Transglycosylase, Slt family compare
Pf6N2E2_2258 -3.2 -13.4 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_5374 -3.2 -8.6 Membrane fusion component of tripartite multidrug resistance system compare
Pf6N2E2_5371 -3.0 -14.6 Outer membrane component of tripartite multidrug resistance system compare
Pf6N2E2_5508 -3.0 -3.9 Formyltetrahydrofolate deformylase (EC 3.5.1.10) compare
Pf6N2E2_5242 -2.9 -2.0 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_2825 -2.9 -2.8 RND efflux system, outer membrane lipoprotein CmeC compare
Pf6N2E2_5372 -2.8 -11.8 Inner membrane component of tripartite multidrug resistance system compare
Pf6N2E2_5373 -2.7 -10.6 required for cephalothin efflux, together with NodT, MFP and FUSC proteins (Pf6N2E2_5371, Pf6N2E2_5374, Pf6N2E2_5372) (from data) compare
Pf6N2E2_4075 -2.7 -6.8 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) compare
Pf6N2E2_5027 -2.6 -14.0 AMP nucleosidase (EC 3.2.2.4) compare
Pf6N2E2_5178 -2.5 -2.8 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) compare
Pf6N2E2_4155 -2.4 -11.0 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
Pf6N2E2_4369 -2.2 -3.1 Exodeoxyribonuclease III (EC 3.1.11.2) compare
Pf6N2E2_4072 -2.1 -6.3 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_3461 -2.1 -2.5 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_1056 -2.0 -3.3 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_621 -1.9 -8.0 TPR domain protein in aerotolerance operon compare
Pf6N2E2_3908 -1.9 -8.2 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_4204 -1.9 -2.9 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
Pf6N2E2_4074 -1.9 -12.8 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) compare
Pf6N2E2_4162 -1.9 -4.5 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_4416 -1.9 -4.1 Tyrosine recombinase XerC compare
Pf6N2E2_3257 -1.8 -5.0 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_624 -1.8 -6.9 hypothetical protein PA3071 compare
Pf6N2E2_3460 -1.8 -2.4 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_2574 -1.8 -2.3 Flagellar synthesis regulator FleN compare
Pf6N2E2_4797 -1.7 -2.4 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_4353 -1.7 -5.2 Hydrogen peroxide-inducible genes activator compare
Pf6N2E2_5824 -1.7 -8.4 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54) compare
Pf6N2E2_4611 -1.7 -5.0 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_2277 -1.7 -3.1 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_3611 -1.7 -2.1 HflC protein compare
Pf6N2E2_2218 -1.6 -4.8 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_2507 -1.6 -6.4 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
Pf6N2E2_2510 -1.6 -3.7 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_5111 -1.6 -4.4 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf6N2E2_3062 -1.5 -5.6 Membrane-associated zinc metalloprotease compare
Pf6N2E2_5014 -1.5 -1.3 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_620 -1.5 -6.9 BatD compare
Pf6N2E2_1083 -1.5 -2.6 hypothetical protein compare
Pf6N2E2_4928 -1.5 -2.0 Permeases of the major facilitator superfamily compare
Pf6N2E2_2181 -1.4 -2.0 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_622 -1.4 -3.7 BatA (Bacteroides aerotolerance operon) compare
Pf6N2E2_5704 -1.4 -5.2 Transcriptional regulatory protein PhoP compare
Pf6N2E2_5103 -1.4 -1.4 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_2940 -1.4 -5.4 OmpA family protein compare
Pf6N2E2_2508 -1.3 -3.3 hypothetical protein compare
Pf6N2E2_288 -1.3 -2.3 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42); Monomeric isocitrate dehydrogenase [NADP] (EC 1.1.1.42) compare
Pf6N2E2_4187 -1.3 -3.8 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_3617 -1.3 -5.5 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
Pf6N2E2_5703 -1.3 -5.4 outer membrane protein H1 compare
Pf6N2E2_3791 -1.3 -7.8 Glucans biosynthesis glucosyltransferase H (EC 2.4.1.-) compare
Pf6N2E2_4181 -1.3 -1.6 Organic hydroperoxide resistance protein compare
Pf6N2E2_2526 -1.3 -4.0 Similar to phosphoglycolate phosphatase, clustered with ubiquinone biosynthesis SAM-dependent O-methyltransferase compare
Pf6N2E2_5321 -1.3 -7.3 Heme O synthase, protoheme IX farnesyltransferase (EC 2.5.1.-) COX10-CtaB compare
Pf6N2E2_4153 -1.2 -2.0 Sensory box histidine kinase compare
Pf6N2E2_625 -1.2 -3.7 MoxR-like ATPase in aerotolerance operon compare
Pf6N2E2_5320 -1.2 -7.0 Cytochrome O ubiquinol oxidase subunit IV (EC 1.10.3.-) compare
Pf6N2E2_3261 -1.2 -4.0 hypothetical protein compare
Pf6N2E2_2217 -1.2 -4.5 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_4041 -1.2 -9.8 Acetyl-CoA hydrolase (EC 3.1.2.1) compare
Pf6N2E2_178 -1.2 -1.4 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_5338 -1.2 -7.1 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare
Pf6N2E2_1312 -1.2 -3.2 4-hydroxyphenylacetate symporter, major facilitator superfamily (MFS) compare
Pf6N2E2_5150 -1.2 -4.6 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_5319 -1.2 -6.0 Cytochrome O ubiquinol oxidase subunit III (EC 1.10.3.-) compare
Pf6N2E2_2986 -1.1 -3.0 Transcriptional regulator, LuxR family compare
Pf6N2E2_4272 -1.1 -3.8 putative membrane protein compare
Pf6N2E2_3258 -1.1 -4.3 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_4273 -1.1 -6.0 ATP-dependent DNA helicase UvrD/PcrA compare
Pf6N2E2_5727 -1.1 -4.2 FIG00955360: hypothetical protein compare
Pf6N2E2_2513 -1.1 -3.7 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf6N2E2_4585 -1.1 -8.4 Cell division protein FtsX compare
Pf6N2E2_5339 -1.1 -5.3 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf6N2E2_2318 -1.1 -5.6 Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_5370 -1.1 -6.6 LysR family transcriptional regulator QseA compare
Pf6N2E2_3260 -1.1 -4.8 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_2790 -1.1 -2.9 Helix-turn-helix motif compare
Pf6N2E2_3666 -1.1 -3.8 InaA protein compare
Pf6N2E2_623 -1.1 -0.9 FIG00954674: hypothetical protein compare
Pf6N2E2_649 -1.1 -2.5 General secretion pathway protein L compare
Pf6N2E2_445 -1.0 -4.7 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) compare
Pf6N2E2_4612 -1.0 -4.0 Glutathione synthetase (EC 6.3.2.3) compare
Pf6N2E2_5406 -1.0 -2.7 FIG00958224: hypothetical protein compare
Pf6N2E2_4599 -1.0 -3.0 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) compare
Pf6N2E2_3060 -1.0 -1.4 Outer membrane protein H precursor compare
Pf6N2E2_3979 -1.0 -7.5 Type I secretion system ATPase, LssB family LapB compare
Pf6N2E2_3761 -1.0 -8.6 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) compare
Pf6N2E2_2373 -1.0 -2.7 Type III secretion thermoregulatory protein (LcrF,VirF,transcription regulation of virulence plasmid) compare
Pf6N2E2_3612 -1.0 -2.1 HflK protein compare
Pf6N2E2_3326 -1.0 -1.1 hypothetical protein compare
Pf6N2E2_1691 -1.0 -1.2 hypothetical protein compare
Pf6N2E2_3656 -1.0 -4.5 Probable transcription regulator Mig-14 compare
Pf6N2E2_5760 -1.0 -7.7 Sensory box histidine kinase/response regulator compare
Pf6N2E2_156 -1.0 -1.5 Carbon storage regulator compare
Pf6N2E2_3744 -1.0 -2.6 General secretion pathway protein F compare
Pf6N2E2_3487 -1.0 -5.7 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_2552 -1.0 -4.0 Cytochrome c heme lyase subunit CcmH compare
Pf6N2E2_1424 -1.0 -1.6 transcriptional regulator, TetR family compare
Pf6N2E2_4352 -1.0 -2.1 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_4159 -0.9 -2.3 Cytochrome c4 compare
Pf6N2E2_3980 -0.9 -6.7 Type I secretion system, outer membrane component LapE compare
Pf6N2E2_4059 -0.9 -1.1 DNA-binding protein HU-alpha compare
Pf6N2E2_5252 -0.9 -1.1 FIG00956396: hypothetical protein compare
Pf6N2E2_4584 -0.9 -2.2 Cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1) compare
Pf6N2E2_4351 -0.9 -5.7 Predicted signal transduction protein compare
Pf6N2E2_3792 -0.9 -4.6 Glucans biosynthesis protein G precursor compare
Pf6N2E2_3786 -0.9 -2.4 Twin-arginine translocation protein TatC compare
Pf6N2E2_5318 -0.9 -7.7 Cytochrome O ubiquinol oxidase subunit I (EC 1.10.3.-) compare
Pf6N2E2_5677 -0.9 -1.1 Carbon storage regulator compare
Pf6N2E2_3981 -0.9 -7.9 T1SS secreted agglutinin RTX compare
Pf6N2E2_4451 -0.9 -4.1 FIG139438: lipoprotein B compare
Pf6N2E2_3753 -0.9 -7.0 DamX, an inner membrane protein involved in bile resistance compare
Pf6N2E2_362 -0.9 -3.1 Dipeptide transport system permease protein dppC compare
Pf6N2E2_3978 -0.9 -7.0 Type I secretion system, membrane fusion protein LapC compare
Pf6N2E2_896 -0.9 -2.6 Regulatory protein, LysR:LysR, substrate-binding compare
Pf6N2E2_2188 -0.9 -3.1 Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family compare
Pf6N2E2_2999 -0.9 -2.0 probable tail fiber assembly protein compare
Pf6N2E2_1385 -0.9 -1.8 FIG00956261: hypothetical protein compare
Pf6N2E2_4362 -0.9 -3.1 DNA-directed RNA polymerase omega subunit (EC 2.7.7.6) compare
Pf6N2E2_5337 -0.9 -2.4 Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) compare
Pf6N2E2_4417 -0.9 -2.6 Protein of unknown function DUF484 compare
Pf6N2E2_2261 -0.8 -4.3 VacJ-like lipoprotein precursor compare
Pf6N2E2_6058 -0.8 -3.8 FIG139976: hypothetical protein compare
Pf6N2E2_2642 -0.8 -5.3 putative patatin-like phospholipase compare
Pf6N2E2_4147 -0.8 -5.5 Fused spore maturation proteins A and B compare
Pf6N2E2_712 -0.8 -2.7 hypothetical protein compare
Pf6N2E2_5499 -0.8 -1.1 hypothetical protein compare
Pf6N2E2_3983 -0.8 -6.3 Membrane bound c-di-GMP receptor LapD compare
Pf6N2E2_3505 -0.8 -1.0 Translation initiation factor SUI1-related protein compare
Pf6N2E2_1305 -0.8 -2.1 Homoprotocatechuate degradative operon repressor compare
Pf6N2E2_5340 -0.8 -2.7 Stringent starvation protein A compare
Pf6N2E2_3542 -0.8 -6.9 Outer membrane receptor proteins, mostly Fe transport compare
Pf6N2E2_3624 -0.8 -4.3 Flagellar motor rotation protein MotB compare
Pf6N2E2_3040 -0.8 -3.5 5-nucleotidase SurE (EC 3.1.3.5) compare
Pf6N2E2_2397 -0.8 -1.1 Two-component system response regulator QseB compare
Pf6N2E2_1113 -0.8 -1.6 Transcriptional regulator, TetR family compare
Pf6N2E2_5920 -0.8 -3.4 Type II/IV secretion system secretin RcpA/CpaC, associated with Flp pilus assembly compare
Pf6N2E2_2938 -0.8 -3.1 Outer membrane lipoprotein compare
Pf6N2E2_3373 -0.8 -1.3 Outer membrane lipoprotein SmpA, a component of the essential YaeT outer-membrane protein assembly complex compare
Pf6N2E2_4678 -0.8 -0.8 hypothetical protein compare
Pf6N2E2_2579 -0.8 -4.1 Flagellar biosynthesis protein FliQ compare
Pf6N2E2_3625 -0.8 -5.6 Flagellar motor rotation protein MotA compare
Pf6N2E2_3151 -0.8 -2.7 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_1463 -0.8 -1.9 Isochorismate pyruvate-lyase (EC 4.-.-.-) compare
Pf6N2E2_1116 -0.8 -1.2 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) compare
Pf6N2E2_4073 -0.8 -3.3 Phosphate transport system permease protein PstA (TC 3.A.1.7.1) compare
Pf6N2E2_2591 -0.8 -3.3 Flagellar assembly protein FliH compare
Pf6N2E2_6085 -0.8 -1.8 Aha1 domain superfamily compare
Pf6N2E2_1128 -0.8 -1.9 Two-component response regulator compare
Pf6N2E2_4128 -0.8 -2.6 hypothetical protein compare
Pf6N2E2_3655 -0.8 -5.5 Hypothetical protein FIG015671 in large core OS assembly cluster compare
Pf6N2E2_919 -0.8 -1.5 FIG00954373: hypothetical protein compare
Pf6N2E2_1673 -0.8 -2.0 Transcriptional regulator, TetR family compare
Pf6N2E2_3039 -0.8 -3.2 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf6N2E2_4010 -0.7 -3.9 Fatty acid desaturase (EC 1.14.19.1); Delta-9 fatty acid desaturase (EC 1.14.19.1) compare
Pf6N2E2_5086 -0.7 -1.1 hypothetical protein compare
Pf6N2E2_737 -0.7 -0.9 Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4) compare
Pf6N2E2_350 -0.7 -1.7 Gfa-like protein compare
Pf6N2E2_2578 -0.7 -1.4 Flagellar biosynthesis protein FliR compare
Pf6N2E2_3270 -0.7 -2.2 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
Pf6N2E2_3782 -0.7 -1.7 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_2605 -0.7 -2.6 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
Pf6N2E2_5328 -0.7 -2.4 FIG00958649: hypothetical protein compare
Pf6N2E2_895 -0.7 -3.0 Transcriptional regulator, HxlR family compare
Pf6N2E2_1140 -0.7 -1.5 Polymyxin resistance protein ArnC, glycosyl transferase (EC 2.4.-.-) compare
Pf6N2E2_1034 -0.7 -0.9 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_2592 -0.7 -3.1 Flagellar motor switch protein FliG compare
Pf6N2E2_3834 -0.7 -3.1 Lipoprotein NlpD compare
Pf6N2E2_6099 -0.7 -1.0 tRNA-Glu-TTC compare
Pf6N2E2_726 -0.7 -2.4 Nitrate/nitrite sensor protein (EC 2.7.3.-) compare
Pf6N2E2_5771 -0.7 -3.9 FKBP-type peptidyl-prolyl cis-trans isomerase FklB (EC 5.2.1.8) compare
Pf6N2E2_1323 -0.7 -1.2 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) compare
Pf6N2E2_5181 -0.7 -5.3 Paraquat-inducible protein A compare
Pf6N2E2_5236 -0.7 -1.4 hypothetical protein compare
Pf6N2E2_5081 -0.7 -1.4 hypothetical protein compare
Pf6N2E2_4414 -0.7 -1.8 FIG00953808: hypothetical protein compare
Pf6N2E2_3713 -0.7 -2.1 Acyl carrier protein compare
Pf6N2E2_2606 -0.7 -3.2 hypothetical protein compare
Pf6N2E2_3770 -0.7 -1.7 ATP-dependent hsl protease ATP-binding subunit HslU compare
Pf6N2E2_3514 -0.7 -1.3 Ribosomal protein L11 methyltransferase (EC 2.1.1.-) compare
Pf6N2E2_3569 -0.7 -1.1 hypothetical protein compare
Pf6N2E2_2106 -0.7 -1.4 hypothetical protein compare
Pf6N2E2_5555 -0.7 -0.7 Cold shock protein CspA compare
Pf6N2E2_127 -0.7 -1.0 AttE component of AttEFGH ABC transport system compare
Pf6N2E2_1560 -0.7 -1.3 Glycine cleavage system transcriptional activator GcvA compare
Pf6N2E2_4071 -0.6 -2.4 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_4710 -0.6 -1.6 hypothetical protein compare
Pf6N2E2_3015 -0.6 -2.4 hypothetical protein compare
Pf6N2E2_5671 -0.6 -1.5 Succinylglutamate desuccinylase (EC 3.5.1.96) compare


Specific Phenotypes

For 7 genes in this experiment

For stress Cephalothin sodium salt in Pseudomonas fluorescens FW300-N2E2

For stress Cephalothin sodium salt across organisms