Experiment set3IT050 for Methanococcus maripaludis JJ

Compare to:

formate McAA nicotinic acid dropout

200 most important genes:

  gene name fitness t score description  
MMJJ_RS00235 -5.9 -22.5 hypothetical protein compare
MMJJ_RS05450 -4.9 -21.5 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMJJ_RS05070 -4.8 -3.3 DNA primase catalytic subunit PriS compare
MMJJ_RS00570 -4.8 -3.2 ribonuclease P compare
MMJJ_RS07000 -4.7 -2.9 TrkH family potassium uptake protein compare
MMJJ_RS06510 -4.7 -4.6 LL-diaminopimelate aminotransferase compare
MMJJ_RS00275 -4.7 -4.1 coenzyme F420-0:L-glutamate ligase compare
MMJJ_RS06860 -4.5 -6.0 hypothetical protein compare
MMJJ_RS08320 -4.5 -4.2 CDP-diacylglycerol--serine O-phosphatidyltransferase compare
MMJJ_RS03615 -4.4 -5.2 cobalt-precorrin-8 methylmutase compare
MMJJ_RS06695 -4.4 -5.0 amidohydrolase compare
MMJJ_RS03820 -4.4 -5.1 hydrogenase formation protein HypD compare
MMJJ_RS04200 -4.4 -9.3 triphosphoribosyl-dephospho-CoA synthase compare
MMJJ_RS03580 -4.3 -5.1 TIGR00303 family protein compare
MMJJ_RS02920 -4.1 -3.9 30S ribosomal protein S27ae compare
MMJJ_RS06490 -4.0 -4.7 methanogenesis marker 2 protein compare
MMJJ_RS05260 -4.0 -8.6 ATP-grasp domain-containing protein compare
MMJJ_RS05225 -3.9 -1.6 Gar1/Naf1 family protein compare
MMJJ_RS07950 -3.9 -4.7 4Fe-4S binding protein compare
MMJJ_RS06240 -3.8 -4.3 dihydropteroate synthase-like protein compare
MMJJ_RS06155 -3.8 -8.4 phosphatidylglycerophosphatase A compare
MMJJ_RS00210 -3.8 -4.0 DUF530 family protein compare
MMJJ_RS03270 -3.8 -3.5 ribosome biogenesis/translation initiation ATPase RLI compare
MMJJ_RS08250 -3.8 -8.9 hydrogenase maturation peptidase HycI compare
MMJJ_RS04975 -3.8 -3.2 glycosyltransferase family 4 protein compare
MMJJ_RS04475 -3.7 -7.0 3,4-dihydroxy-2-butanone-4-phosphate synthase compare
MMJJ_RS00450 -3.7 -3.0 DUF126 domain-containing protein compare
MMJJ_RS04485 -3.7 -12.8 riboflavin synthase compare
MMJJ_RS02090 -3.7 -7.3 tyramine--L-glutamate ligase compare
MMJJ_RS03840 -3.7 -5.5 DHH family phosphoesterase compare
MMJJ_RS03005 -3.7 -5.5 Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit compare
MMJJ_RS06180 -3.6 -4.2 tryptophan--tRNA ligase compare
MMJJ_RS07665 -3.6 -21.7 formate dehydrogenase subunit alpha compare
MMJJ_RS06840 -3.6 -5.5 nickel-dependent hydrogenase large subunit compare
MMJJ_RS00125 -3.6 -3.4 KEOPS complex subunit Cgi121 compare
MMJJ_RS07670 -3.6 -18.3 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain compare
MMJJ_RS04050 -3.5 -2.8 dihydroneopterin aldolase family protein compare
MMJJ_RS05935 -3.5 -3.5 Era-like GTP-binding protein compare
MMJJ_RS07720 -3.5 -3.1 UPF0058 family protein compare
MMJJ_RS01935 -3.5 -6.8 O-phosphoseryl-tRNA(Sec) selenium transferase compare
MMJJ_RS05330 -3.5 -3.4 DNA polymerase II large subunit compare
MMJJ_RS07350 -3.5 -5.2 4Fe-4S binding protein compare
MMJJ_RS07655 -3.5 -14.7 hypothetical protein compare
MMJJ_RS06875 -3.5 -4.9 hypothetical protein compare
MMJJ_RS06040 -3.4 -5.4 NADH-quinone oxidoreductase subunit H compare
MMJJ_RS05535 -3.4 -14.4 hypothetical protein compare
MMJJ_RS08625 -3.4 -8.4 magnesium/cobalt transporter CorA compare
MMJJ_RS04800 -3.4 -7.2 2-phospho-L-lactate guanylyltransferase compare
MMJJ_RS04155 -3.4 -9.4 hypothetical protein compare
MMJJ_RS04995 -3.3 -8.3 Tfx family DNA-binding protein compare
MMJJ_RS08020 -3.3 -9.7 nucleotidyltransferase domain-containing protein compare
MMJJ_RS08055 -3.3 -9.4 methanogenesis marker 14 protein compare
MMJJ_RS06725 -3.3 -14.9 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMJJ_RS02045 -3.3 -4.4 molybdenum cofactor guanylyltransferase compare
MMJJ_RS02040 -3.2 -3.1 Asp-tRNA(Asn) amidotransferase subunit GatC compare
MMJJ_RS03150 -3.2 -9.2 2-phospho-L-lactate transferase compare
MMJJ_RS06255 -3.2 -8.3 tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3 compare
MMJJ_RS08850 -3.2 -3.7 succinate dehydrogenase/fumarate reductase iron-sulfur subunit compare
MMJJ_RS03055 -3.2 -3.3 hypothetical protein compare
MMJJ_RS01755 -3.2 -3.7 ferrous iron transport protein B compare
MMJJ_RS07380 -3.1 -9.8 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMJJ_RS08080 -3.1 -12.3 TIGR00300 family protein compare
MMJJ_RS05950 -3.1 -5.3 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase compare
MMJJ_RS06915 -3.1 -16.2 helix-turn-helix domain-containing protein compare
MMJJ_RS06910 -3.1 -3.1 energy-converting NiFe hydrogenase A subunit EhaA compare
MMJJ_RS06930 -3.0 -4.2 type II methionyl aminopeptidase compare
MMJJ_RS06215 -3.0 -5.5 agmatinase compare
MMJJ_RS01870 -3.0 -3.0 methanogenesis marker 15 protein compare
MMJJ_RS07705 -3.0 -4.9 GTP-binding protein EngB compare
MMJJ_RS07430 -3.0 -6.1 ribonuclease VapC compare
MMJJ_RS03200 -3.0 -3.5 uroporphyrinogen-III synthase compare
MMJJ_RS07410 -3.0 -5.9 methanogenesis marker protein Mmp4/MtxX compare
MMJJ_RS06250 -3.0 -3.4 nicotinamide-nucleotide adenylyltransferase compare
MMJJ_RS04685 -3.0 -10.5 carbamoyltransferase HypF compare
MMJJ_RS06625 -3.0 -2.9 pyruvate synthase subunit PorB compare
MMJJ_RS00560 -3.0 -5.2 homoisocitrate dehydrogenase compare
MMJJ_RS08005 -3.0 -16.3 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMJJ_RS04150 -2.9 -3.4 DUF5379 domain-containing protein compare
MMJJ_RS08335 -2.9 -3.1 ABC transporter ATP-binding protein compare
MMJJ_RS03295 -2.9 -15.1 PHP domain-containing protein compare
MMJJ_RS07945 -2.9 -4.3 4Fe-4S binding protein compare
MMJJ_RS08000 -2.9 -10.1 HesA/MoeB/ThiF family protein compare
MMJJ_RS06110 -2.8 -3.4 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC compare
MMJJ_RS03760 -2.8 -5.0 hydrogenase maturation nickel metallochaperone HypA compare
MMJJ_RS04520 -2.8 -4.5 coenzyme F430 synthase compare
MMJJ_RS07190 -2.8 -6.0 RtcB family protein compare
MMJJ_RS05930 -2.8 -2.2 cell division protein SepF compare
MMJJ_RS05490 -2.8 -4.2 imidazole glycerol phosphate synthase subunit HisF compare
MMJJ_RS05650 -2.7 -4.2 formylmethanofuran dehydrogenase subunit B compare
MMJJ_RS08535 -2.7 -3.8 NOL1/NOP2/sun family putative RNA methylase compare
MMJJ_RS08340 -2.7 -5.7 archaeoflavoprotein AfpA compare
MMJJ_RS03670 -2.7 -5.2 precorrin-2 C(20)-methyltransferase compare
MMJJ_RS03865 -2.7 -2.7 phosphoribosyl-AMP cyclohydrolase compare
MMJJ_RS03065 -2.7 -12.0 CBS domain-containing protein compare
MMJJ_RS03190 -2.7 -4.0 phosphopyruvate hydratase compare
MMJJ_RS07785 -2.7 -4.6 fumarate reductase subunit A compare
MMJJ_RS08855 -2.7 -4.3 cyclic pyranopterin monophosphate synthase MoaC compare
MMJJ_RS05620 -2.7 -5.5 CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein compare
MMJJ_RS05065 -2.7 -5.0 (4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase compare
MMJJ_RS01475 -2.6 -3.2 signal recognition particle-docking protein FtsY compare
MMJJ_RS06375 -2.6 -5.1 UbiX family flavin prenyltransferase compare
MMJJ_RS05445 -2.6 -2.6 2-oxoacid:acceptor oxidoreductase subunit alpha compare
MMJJ_RS01200 -2.6 -3.7 PRC-barrel domain-containing protein compare
MMJJ_RS01345 -2.6 -4.6 (5-formylfuran-3-yl)methyl phosphate synthase compare
MMJJ_RS07660 -2.6 -8.4 carbonic anhydrase compare
MMJJ_RS03830 -2.6 -8.9 CBS domain-containing protein compare
MMJJ_RS06805 -2.6 -4.5 monovalent cation/H+ antiporter subunit E compare
MMJJ_RS05575 -2.6 -5.7 2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase compare
MMJJ_RS03125 -2.6 -6.4 GMC oxidoreductase compare
MMJJ_RS06485 -2.6 -4.3 phosphoglycerate kinase compare
MMJJ_RS03620 -2.5 -7.1 DUF2097 domain-containing protein compare
MMJJ_RS04675 -2.5 -6.7 thiamine pyrophosphate-binding protein compare
MMJJ_RS06750 -2.5 -3.9 homoaconitase large subunit compare
MMJJ_RS07275 -2.5 -3.5 formate--phosphoribosylaminoimidazolecarboxamide ligase compare
MMJJ_RS00215 -2.5 -3.6 CCA tRNA nucleotidyltransferase compare
MMJJ_RS07245 -2.5 -5.7 amidohydrolase family protein compare
MMJJ_RS00050 -2.4 -11.5 AAA family ATPase compare
MMJJ_RS00270 -2.4 -3.3 adenosylcobinamide-GDP ribazoletransferase compare
MMJJ_RS06785 -2.4 -8.1 RNA ligase partner protein compare
MMJJ_RS07345 -2.4 -6.3 homocysteine biosynthesis protein compare
MMJJ_RS01865 -2.4 -7.6 peptidyl-tRNA hydrolase Pth2 compare
MMJJ_RS09190 -2.4 -2.8 tryptophan synthase subunit beta compare
MMJJ_RS01750 -2.4 -2.2 ferrous iron transport protein A compare
MMJJ_RS04655 -2.4 -6.2 FAD-dependent oxidoreductase compare
MMJJ_RS06855 -2.4 -2.8 DUF2104 domain-containing protein compare
MMJJ_RS08095 -2.4 -5.7 cobyric acid synthase CobQ compare
MMJJ_RS06225 -2.4 -3.0 adenosylmethionine decarboxylase compare
MMJJ_RS02275 -2.4 -4.9 nucleotidyltransferase domain-containing protein compare
MMJJ_RS03800 -2.4 -11.0 aldolase compare
MMJJ_RS04615 -2.4 -5.0 methanogenesis marker 3 protein compare
MMJJ_RS00520 -2.4 -7.0 PDGLE domain-containing protein compare
MMJJ_RS01565 -2.4 -7.1 TIGR00267 family protein compare
MMJJ_RS05995 -2.4 -3.0 ATP-binding cassette domain-containing protein compare
MMJJ_RS03875 -2.4 -4.4 CBS domain-containing protein compare
MMJJ_RS05655 -2.3 -7.0 HisA/HisF family protein compare
MMJJ_RS05190 -2.3 -6.9 gamma carbonic anhydrase family protein compare
MMJJ_RS00600 -2.3 -3.3 hydroxymethylbilane synthase compare
MMJJ_RS05810 -2.3 -5.4 precorrin-4 C(11)-methyltransferase compare
MMJJ_RS04790 -2.3 -4.4 biotin--[acetyl-CoA-carboxylase] ligase compare
MMJJ_RS09375 -2.3 -2.5 hypothetical protein compare
MMJJ_RS05610 -2.3 -5.5 CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMJJ_RS08660 -2.3 -3.3 acetylornithine transaminase compare
MMJJ_RS08330 -2.3 -3.0 SufD family Fe-S cluster assembly protein compare
MMJJ_RS07035 -2.2 -2.7 glycosyl transferase compare
MMJJ_RS00265 -2.2 -6.3 TIGR02253 family HAD-type hydrolase compare
MMJJ_RS00040 -2.2 -11.6 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMJJ_RS06705 -2.2 -5.4 bifunctional NADP phosphatase/NAD kinase compare
MMJJ_RS07355 -2.2 -4.6 MoaD/ThiS family protein compare
MMJJ_RS01875 -2.2 -6.9 global nitrogen regulator NrpR compare
MMJJ_RS00045 -2.2 -12.8 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMJJ_RS00580 -2.2 -1.9 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG compare
MMJJ_RS07635 -2.2 -13.4 response regulator transcription factor compare
MMJJ_RS02935 -2.2 -3.8 DNA-directed RNA polymerase subunit E'' compare
MMJJ_RS07650 -2.1 -16.5 formate/nitrite transporter family protein compare
MMJJ_RS00075 -2.1 -10.4 AAA family ATPase compare
MMJJ_RS06835 -2.1 -10.8 4Fe-4S binding protein compare
MMJJ_RS06185 -2.1 -6.4 cobalamin biosynthesis protein compare
MMJJ_RS07995 -2.1 -7.1 molybdenum cofactor biosynthesis protein MoaE compare
MMJJ_RS00205 -2.1 -5.4 adenosylcobinamide-phosphate synthase CbiB compare
MMJJ_RS00035 -2.1 -14.2 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMJJ_RS00530 -2.1 -11.9 cobalt ECF transporter T component CbiQ compare
MMJJ_RS03110 -2.1 -5.5 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase compare
MMJJ_RS06175 -2.1 -2.0 DUF1743 domain-containing protein compare
MMJJ_RS03630 -2.1 -11.2 AMP phosphorylase compare
MMJJ_RS01690 -2.1 -3.8 methanogenesis marker 12 protein compare
MMJJ_RS00060 -2.1 -13.8 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMJJ_RS07640 -2.0 -16.4 cache domain-containing protein compare
MMJJ_RS04670 -2.0 -5.2 DUF2117 domain-containing protein compare
MMJJ_RS03660 -2.0 -4.6 DUF447 family protein compare
MMJJ_RS00070 -2.0 -3.1 CooT family nickel-binding protein compare
MMJJ_RS05375 -2.0 -13.3 radical SAM protein compare
MMJJ_RS01600 -2.0 -2.8 radical SAM protein compare
MMJJ_RS06730 -2.0 -6.8 ATP-binding cassette domain-containing protein compare
MMJJ_RS00065 -2.0 -9.3 4Fe-4S dicluster domain-containing protein compare
MMJJ_RS00355 -2.0 -3.7 ribonuclease P protein component 4 compare
MMJJ_RS06050 -2.0 -9.9 molybdopterin molybdotransferase MoeA compare
MMJJ_RS00080 -2.0 -11.4 DUF166 domain-containing protein compare
MMJJ_RS01360 -2.0 -2.9 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMJJ_RS01355 -2.0 -4.3 UDP-N-acetyl-D-mannosamine dehydrogenase compare
MMJJ_RS06010 -2.0 -7.1 hypothetical protein compare
MMJJ_RS03095 -2.0 -2.9 bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase compare
MMJJ_RS01415 -2.0 -3.6 beta-CASP ribonuclease aCPSF1 compare
MMJJ_RS03115 -2.0 -5.9 sulfopyruvate decarboxylase subunit alpha compare
MMJJ_RS07155 -1.9 -7.7 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMJJ_RS08585 -1.9 -10.3 M42 family metallopeptidase compare
MMJJ_RS00370 -1.9 -2.2 asparagine synthase (glutamine-hydrolyzing) compare
MMJJ_RS07415 -1.9 -2.9 polyprenyl diphosphate synthase compare
MMJJ_RS06015 -1.9 -9.9 Na(+)/H(+) antiporter subunit B compare
MMJJ_RS04010 -1.9 -8.7 archaeal proteasome endopeptidase complex subunit alpha compare
MMJJ_RS06170 -1.9 -9.0 hypothetical protein compare
MMJJ_RS04595 -1.9 -5.5 hypothetical protein compare
MMJJ_RS04110 -1.9 -5.1 hypothetical protein compare
MMJJ_RS05295 -1.9 -9.3 cobyrinic acid a,c-diamide synthase compare
MMJJ_RS08065 -1.9 -3.6 precorrin-6Y C5,15-methyltransferase (decarboxylating) subunit CbiT compare
MMJJ_RS07725 -1.9 -6.6 DNA primase DnaG compare
MMJJ_RS08840 -1.9 -4.2 calcium/sodium antiporter compare
MMJJ_RS06000 -1.9 -4.9 cation:proton antiporter subunit C compare
MMJJ_RS00055 -1.8 -7.0 CO dehydrogenase/acetyl-CoA synthase subunit delta compare
MMJJ_RS04985 -1.8 -4.1 glutamyl-tRNA reductase compare
MMJJ_RS08620 -1.8 -3.5 DUF373 family protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis JJ in nutrient t1 experiments