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Experiment set3IT050 for
Methanococcus maripaludis JJ
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formate McAA nicotinic acid dropout
200 most detrimental genes:
gene
name
fitness
t score
description
MMJJ
_RS04415
+2.4
9.1
hypothetical protein
compare
MMJJ
_RS03725
+0.9
3.8
sulfurtransferase TusA family protein
compare
MMJJ
_RS08130
+0.7
0.8
translation initiation factor IF-2 subunit gamma
compare
MMJJ
_RS04005
+0.7
5.6
acetate--CoA ligase family protein
compare
MMJJ
_RS04955
+0.7
4.3
tRNA pseudouridine(54/55) synthase Pus10
compare
MMJJ
_RS06800
+0.6
4.3
prefoldin subunit alpha
compare
MMJJ
_RS07235
+0.6
4.9
coenzyme F420 hydrogenase subunit alpha
compare
MMJJ
_RS03250
+0.5
1.7
DUF2116 family Zn-ribbon domain-containing protein
compare
MMJJ
_RS05685
+0.5
3.0
class III signal peptide-containing protein
compare
MMJJ
_RS08830
+0.5
2.2
hypothetical protein
compare
MMJJ
_RS07015
+0.5
0.7
PFL family protein
compare
MMJJ
_RS07230
+0.5
3.1
coenzyme F420-reducing hydrogenase, FrhD protein
compare
MMJJ
_RS07240
+0.5
4.5
MBL fold metallo-hydrolase
compare
MMJJ
_RS07795
+0.5
2.8
cupin domain-containing protein
compare
MMJJ
_RS06210
+0.5
2.8
hypothetical protein
compare
MMJJ
_RS06680
+0.5
2.9
DUF366 family protein
compare
MMJJ
_RS01855
+0.5
3.7
MBL fold metallo-hydrolase
compare
MMJJ
_RS07220
+0.5
3.7
coenzyme F420 hydrogenase subunit beta
compare
MMJJ
_RS06675
+0.5
3.6
TIGR01212 family radical SAM protein
compare
MMJJ
_RS07920
+0.4
3.1
6-carboxytetrahydropterin synthase QueD
compare
MMJJ
_RS07025
+0.4
2.8
tRNA (cytidine(56)-2'-O)-methyltransferase
compare
MMJJ
_RS03605
+0.4
1.8
TIGR00297 family protein
compare
MMJJ
_RS08485
+0.4
2.2
Lrp/AsnC family transcriptional regulator
compare
MMJJ
_RS07225
+0.4
3.0
coenzyme F420 hydrogenase subunit gamma
compare
MMJJ
_RS04105
+0.4
3.5
prepilin peptidase
compare
MMJJ
_RS06470
+0.4
2.8
tripartite tricarboxylate transporter permease
compare
MMJJ
_RS07985
+0.4
1.9
hypothetical protein
compare
MMJJ
_RS09300
+0.4
1.2
hypothetical protein
compare
MMJJ
_RS04545
+0.4
1.5
PadR family transcriptional regulator
compare
MMJJ
_RS08100
+0.4
2.5
hypothetical protein
compare
MMJJ
_RS06665
+0.4
2.0
DUF3236 domain-containing protein
compare
MMJJ
_RS07270
+0.4
2.6
ribonuclease HII
compare
MMJJ
_RS06770
+0.4
3.2
hypothetical protein
compare
MMJJ
_RS06275
+0.4
1.9
hypothetical protein
compare
MMJJ
_RS06950
+0.4
2.8
4-demethylwyosine synthase TYW1
compare
MMJJ
_RS05580
+0.4
2.8
methanogenesis marker 9 domain-containing protein
compare
MMJJ
_RS08225
+0.4
1.4
peptidylprolyl isomerase
compare
MMJJ
_RS06515
+0.4
2.7
ribonuclease III
compare
MMJJ
_RS07810
+0.4
2.2
3-methyl-2-oxobutanoate dehydrogenase subunit VorB
compare
MMJJ
_RS07010
+0.4
2.1
preprotein translocase subunit Sec61beta
compare
MMJJ
_RS05040
+0.4
2.4
7-carboxy-7-deazaguanine synthase QueE
compare
MMJJ
_RS07280
+0.3
2.0
phosphomannomutase/phosphoglucomutase
compare
MMJJ
_RS01670
+0.3
1.6
hypothetical protein
compare
MMJJ
_RS06505
+0.3
1.2
prephenate dehydratase
compare
MMJJ
_RS03070
+0.3
1.2
MetS family NSS transporter small subunit
compare
MMJJ
_RS03805
+0.3
1.3
hypothetical protein
compare
MMJJ
_RS07800
+0.3
2.7
AMP-binding protein
compare
MMJJ
_RS02665
+0.3
0.9
methyl-accepting chemotaxis protein
compare
MMJJ
_RS08705
+0.3
2.4
AEC family transporter
compare
MMJJ
_RS05520
+0.3
2.6
H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein
compare
MMJJ
_RS09065
+0.3
1.9
hypothetical protein
compare
MMJJ
_RS07740
+0.3
2.3
DUF2334 domain-containing protein
compare
MMJJ
_RS06790
+0.3
2.8
nucleotidyltransferase family protein
compare
MMJJ
_RS06740
+0.3
1.6
energy-coupling factor ABC transporter substrate-binding protein
compare
MMJJ
_RS03515
+0.3
2.2
GPR1/FUN34/YaaH family transporter
compare
MMJJ
_RS06440
+0.3
2.4
DUF4870 domain-containing protein
compare
MMJJ
_RS06500
+0.3
2.0
class I SAM-dependent methyltransferase
compare
MMJJ
_RS02180
+0.3
1.6
DHH family phosphoesterase
compare
MMJJ
_RS06735
+0.3
2.0
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS08455
+0.3
2.2
tetratricopeptide repeat protein
compare
MMJJ
_RS06535
+0.3
2.4
UPF0104 family protein
compare
MMJJ
_RS07680
+0.3
2.2
glucose-6-phosphate isomerase
compare
MMJJ
_RS08410
+0.3
1.2
CBS domain-containing protein
compare
MMJJ
_RS08315
+0.3
2.2
DNA protection protein DPS
compare
MMJJ
_RS05510
+0.3
2.2
archaellum operon transcriptional activator EarA family protein
compare
MMJJ
_RS07915
+0.3
1.5
CBS domain-containing protein
compare
MMJJ
_RS06810
+0.3
2.3
L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha
compare
MMJJ
_RS06745
+0.3
2.1
energy-coupling factor ABC transporter permease
compare
MMJJ
_RS08240
+0.3
1.9
L-fuculose phosphate aldolase
compare
MMJJ
_RS07260
+0.3
1.7
PspC domain-containing protein
compare
MMJJ
_RS02270
+0.3
1.2
HEPN domain-containing protein
compare
MMJJ
_RS05975
+0.3
1.8
sulfurtransferase TusA family protein
compare
MMJJ
_RS07805
+0.3
1.3
ferredoxin family protein
compare
MMJJ
_RS01265
+0.3
1.5
cupin domain-containing protein
compare
MMJJ
_RS07005
+0.3
1.4
transcription factor S
compare
MMJJ
_RS06460
+0.3
1.7
cytochrome c
compare
MMJJ
_RS08525
+0.3
1.3
peptidylprolyl isomerase
compare
MMJJ
_RS06585
+0.3
1.8
alanine racemase
compare
MMJJ
_RS07835
+0.3
1.8
UPF0489 family protein
compare
MMJJ
_RS07210
+0.3
2.1
AmmeMemoRadiSam system protein B
compare
MMJJ
_RS07890
+0.3
1.7
pyrimidine dimer DNA glycosylase/endonuclease V
compare
MMJJ
_RS00150
+0.3
1.6
DUF2180 family protein
compare
MMJJ
_RS04580
+0.3
1.9
2-phosphosulfolactate phosphatase
compare
MMJJ
_RS06710
+0.3
2.1
TldD/PmbA family protein
compare
MMJJ
_RS01010
+0.3
2.4
right-handed parallel beta-helix repeat-containing protein
compare
MMJJ
_RS03835
+0.2
1.3
DUF504 domain-containing protein
compare
MMJJ
_RS06190
+0.2
1.9
7-cyano-7-deazaguanine synthase
compare
MMJJ
_RS09295
+0.2
0.3
hypothetical protein
compare
MMJJ
_RS05500
+0.2
2.3
hypothetical protein
compare
MMJJ
_RS05505
+0.2
2.3
hypothetical protein
compare
MMJJ
_RS06090
+0.2
1.3
hypothetical protein
compare
MMJJ
_RS01955
+0.2
2.0
hypothetical protein
compare
MMJJ
_RS06685
+0.2
2.1
S-layer protein
compare
MMJJ
_RS09390
+0.2
0.5
hypothetical protein
compare
MMJJ
_RS00615
+0.2
1.3
nucleoside deaminase
compare
MMJJ
_RS08515
+0.2
0.8
secondary thiamine-phosphate synthase enzyme YjbQ
compare
MMJJ
_RS06120
+0.2
1.6
DUF4013 domain-containing protein
compare
MMJJ
_RS06205
+0.2
1.7
EamA family transporter
compare
MMJJ
_RS01300
+0.2
1.3
MarR family transcriptional regulator
compare
MMJJ
_RS05980
+0.2
1.5
DUF5400 domain-containing protein
compare
MMJJ
_RS05690
+0.2
2.1
hypothetical protein
compare
MMJJ
_RS04215
+0.2
1.9
DMT family transporter
compare
MMJJ
_RS05605
+0.2
1.1
hypothetical protein
compare
MMJJ
_RS09360
+0.2
1.5
hypothetical protein
compare
MMJJ
_RS03040
+0.2
1.5
lactate utilization protein
compare
MMJJ
_RS05355
+0.2
1.7
DUF2121 domain-containing protein
compare
MMJJ
_RS07495
+0.2
1.3
4Fe-4S binding protein
compare
MMJJ
_RS09005
+0.2
1.9
N-6 DNA methylase
compare
MMJJ
_RS05400
+0.2
1.3
CoA-binding protein
compare
MMJJ
_RS06520
+0.2
1.6
TldD/PmbA family protein
compare
MMJJ
_RS06580
+0.2
1.6
alanine dehydrogenase
compare
MMJJ
_RS06960
+0.2
1.9
CAP domain-containing protein
compare
MMJJ
_RS03360
+0.2
0.2
hypothetical protein
compare
MMJJ
_RS06130
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS07450
+0.2
1.1
hypothetical protein
compare
MMJJ
_RS04610
+0.2
1.0
ribosome assembly RNA-binding protein YhbY
compare
MMJJ
_RS05915
+0.2
0.7
multiprotein bridging factor aMBF1
compare
MMJJ
_RS05390
+0.2
1.6
tRNA pseudouridine(13) synthase TruD
compare
MMJJ
_RS06495
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS01435
+0.2
1.6
4Fe-4S binding protein
compare
MMJJ
_RS09365
+0.2
0.5
hypothetical protein
compare
MMJJ
_RS05960
+0.2
1.5
DUF169 domain-containing protein
compare
MMJJ
_RS07445
+0.2
1.4
RlmF-related methyltransferase
compare
MMJJ
_RS07815
+0.2
1.5
2-oxoacid:acceptor oxidoreductase family protein
compare
MMJJ
_RS06765
+0.2
1.7
hypothetical protein
compare
MMJJ
_RS07480
+0.2
1.7
FAD-dependent oxidoreductase
compare
MMJJ
_RS04220
+0.2
1.3
helix-turn-helix transcriptional regulator
compare
MMJJ
_RS04715
+0.2
0.9
hypothetical protein
compare
MMJJ
_RS02230
+0.2
1.6
hypothetical protein
compare
MMJJ
_RS01515
+0.2
0.9
DUF2178 domain-containing protein
compare
MMJJ
_RS08305
+0.2
1.1
peroxiredoxin
compare
MMJJ
_RS05700
+0.2
1.4
metallophosphoesterase
compare
MMJJ
_RS02240
+0.2
0.8
CGGC domain-containing protein
compare
MMJJ
_RS00145
+0.2
1.4
aquaporin family protein
compare
MMJJ
_RS07855
+0.2
1.4
YkgJ family cysteine cluster protein
compare
MMJJ
_RS04135
+0.2
0.8
7-cyano-7-deazaguanine synthase QueC
compare
MMJJ
_RS07865
+0.2
1.2
zinc ribbon domain-containing protein
compare
MMJJ
_RS07820
+0.2
1.3
bifunctional hexulose-6-phosphate synthase/ribonuclease regulator
compare
MMJJ
_RS05660
+0.2
1.0
sulfopyruvate decarboxylase subunit beta
compare
MMJJ
_RS08165
+0.2
1.1
thermonuclease family protein
compare
MMJJ
_RS03375
+0.2
1.1
hypothetical protein
compare
MMJJ
_RS07215
+0.2
1.5
TIGR00341 family protein
compare
MMJJ
_RS08300
+0.2
1.4
hypothetical protein
compare
MMJJ
_RS06540
+0.2
1.0
DUF2120 domain-containing protein
compare
MMJJ
_RS02340
+0.2
1.0
SAM-dependent methyltransferase
compare
MMJJ
_RS04375
+0.2
0.5
hypothetical protein
compare
MMJJ
_RS09335
+0.2
0.8
hypothetical protein
compare
MMJJ
_RS06085
+0.2
0.8
proteasome assembly chaperone family protein
compare
MMJJ
_RS01835
+0.2
1.4
tRNA pseudouridine(13) synthase TruD
compare
MMJJ
_RS03775
+0.2
0.5
50S ribosomal protein L15e
compare
MMJJ
_RS07200
+0.2
1.4
MFS transporter
compare
MMJJ
_RS06280
+0.2
1.3
hypothetical protein
compare
MMJJ
_RS08045
+0.2
1.4
transporter substrate-binding domain-containing protein
compare
MMJJ
_RS02160
+0.2
1.1
amino acid ABC transporter permease
compare
MMJJ
_RS04965
+0.2
0.5
RNA polymerase Rpb4 family protein
compare
MMJJ
_RS07765
+0.2
0.7
DMT family protein
compare
MMJJ
_RS05410
+0.2
1.0
RecB-family nuclease
compare
MMJJ
_RS07830
+0.2
1.2
DUF1786 domain-containing protein
compare
MMJJ
_RS06640
+0.2
1.1
YfcE family phosphodiesterase
compare
MMJJ
_RS08375
+0.2
1.2
ferritin
compare
MMJJ
_RS08580
+0.2
0.9
YkgJ family cysteine cluster protein
compare
MMJJ
_RS02335
+0.2
1.4
ABC transporter substrate-binding protein
compare
MMJJ
_RS02115
+0.2
1.1
class I SAM-dependent methyltransferase family protein
compare
MMJJ
_RS05790
+0.2
1.2
flagellin
compare
MMJJ
_RS01825
+0.2
0.8
DNA repair and recombination protein RadB
compare
MMJJ
_RS01800
+0.2
1.2
ADP-ribosylglycohydrolase family protein
compare
MMJJ
_RS02865
+0.2
1.1
amino acid ABC transporter substrate-binding protein
compare
MMJJ
_RS06455
+0.2
1.2
YeeE/YedE family protein
compare
MMJJ
_RS03905
+0.2
0.8
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS04350
+0.2
0.6
hypothetical protein
compare
MMJJ
_RS07595
+0.2
0.9
hypothetical protein
compare
MMJJ
_RS00500
+0.2
0.6
GNAT family N-acetyltransferase
compare
MMJJ
_RS01590
+0.2
0.4
adenine phosphoribosyltransferase
compare
MMJJ
_RS05335
+0.2
1.0
heavy metal-binding domain-containing protein
compare
MMJJ
_RS08810
+0.1
0.2
DUF4040 domain-containing protein
compare
MMJJ
_RS05750
+0.1
1.1
flagellar accessory protein FlaH
compare
MMJJ
_RS01795
+0.1
1.1
TIGR00266 family protein
compare
MMJJ
_RS07685
+0.1
1.2
glycogen/starch synthase
compare
MMJJ
_RS05530
+0.1
0.5
roadblock/LC7 domain-containing protein
compare
MMJJ
_RS02010
+0.1
1.0
MBL fold metallo-hydrolase
compare
MMJJ
_RS07365
+0.1
1.1
CatB-related O-acetyltransferase
compare
MMJJ
_RS01125
+0.1
0.6
hypothetical protein
compare
MMJJ
_RS04180
+0.1
0.4
metalloregulator ArsR/SmtB family transcription factor
compare
MMJJ
_RS02355
+0.1
1.0
DUF2798 domain-containing protein
compare
MMJJ
_RS00155
+0.1
1.2
DUF2193 domain-containing protein
compare
MMJJ
_RS03025
+0.1
1.2
Ig-like domain-containing protein
compare
MMJJ
_RS00785
+0.1
0.4
hypothetical protein
compare
MMJJ
_RS04345
+0.1
0.4
DUF2080 family transposase-associated protein
compare
MMJJ
_RS08040
+0.1
1.1
NAD(P)/FAD-dependent oxidoreductase
compare
MMJJ
_RS08665
+0.1
1.2
transcriptional regulator
compare
MMJJ
_RS08350
+0.1
1.2
heavy metal translocating P-type ATPase
compare
MMJJ
_RS07695
+0.1
1.2
glycoside hydrolase family 15 protein
compare
MMJJ
_RS09120
+0.1
0.2
aspartate kinase
compare
MMJJ
_RS00810
+0.1
1.0
GTP-binding protein
compare
MMJJ
_RS01380
+0.1
0.9
DUF1890 domain-containing protein
compare
MMJJ
_RS04825
+0.1
1.1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
compare
MMJJ
_RS08215
+0.1
1.0
radical SAM protein
compare
MMJJ
_RS03045
+0.1
1.0
hypothetical protein
compare
MMJJ
_RS05365
+0.1
0.7
DUF2798 domain-containing protein
compare
MMJJ
_RS08210
+0.1
1.3
hypothetical protein
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments