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Experiment set3IT049 for
Methanococcus maripaludis JJ
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formate McAA nicotinic acid dropout
200 most important genes:
gene
name
fitness
t score
description
MMJJ
_RS00235
-6.4
-22.9
hypothetical protein
compare
MMJJ
_RS09375
-5.5
-2.8
hypothetical protein
compare
MMJJ
_RS00275
-5.5
-3.6
coenzyme F420-0:L-glutamate ligase
compare
MMJJ
_RS06860
-5.4
-6.4
hypothetical protein
compare
MMJJ
_RS06625
-5.4
-3.2
pyruvate synthase subunit PorB
compare
MMJJ
_RS04485
-5.3
-11.3
riboflavin synthase
compare
MMJJ
_RS02040
-5.3
-3.4
Asp-tRNA(Asn) amidotransferase subunit GatC
compare
MMJJ
_RS08320
-5.1
-3.2
CDP-diacylglycerol--serine O-phosphatidyltransferase
compare
MMJJ
_RS02045
-4.8
-4.7
molybdenum cofactor guanylyltransferase
compare
MMJJ
_RS01870
-4.6
-3.0
methanogenesis marker 15 protein
compare
MMJJ
_RS04200
-4.6
-7.1
triphosphoribosyl-dephospho-CoA synthase
compare
MMJJ
_RS05450
-4.5
-17.8
TIGR03576 family pyridoxal phosphate-dependent enzyme
compare
MMJJ
_RS08660
-4.4
-4.2
acetylornithine transaminase
compare
MMJJ
_RS05445
-4.3
-3.1
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
MMJJ
_RS06040
-4.3
-5.8
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS01935
-4.2
-7.0
O-phosphoseryl-tRNA(Sec) selenium transferase
compare
MMJJ
_RS03760
-4.2
-5.7
hydrogenase maturation nickel metallochaperone HypA
compare
MMJJ
_RS03580
-4.1
-5.6
TIGR00303 family protein
compare
MMJJ
_RS06510
-4.1
-4.6
LL-diaminopimelate aminotransferase
compare
MMJJ
_RS03895
-4.1
-4.4
hydrogenase expression/formation protein HypE
compare
MMJJ
_RS01810
-4.0
-3.1
methyl coenzyme M reductase system, component A2
compare
MMJJ
_RS05935
-4.0
-4.1
Era-like GTP-binding protein
compare
MMJJ
_RS03055
-4.0
-4.0
hypothetical protein
compare
MMJJ
_RS02920
-4.0
-3.6
30S ribosomal protein S27ae
compare
MMJJ
_RS01600
-4.0
-4.6
radical SAM protein
compare
MMJJ
_RS03840
-3.9
-5.3
DHH family phosphoesterase
compare
MMJJ
_RS05490
-3.9
-3.8
imidazole glycerol phosphate synthase subunit HisF
compare
MMJJ
_RS05995
-3.9
-3.2
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS03200
-3.9
-3.5
uroporphyrinogen-III synthase
compare
MMJJ
_RS06490
-3.8
-4.4
methanogenesis marker 2 protein
compare
MMJJ
_RS04050
-3.8
-3.0
dihydroneopterin aldolase family protein
compare
MMJJ
_RS07950
-3.8
-4.4
4Fe-4S binding protein
compare
MMJJ
_RS05950
-3.8
-5.1
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
compare
MMJJ
_RS03875
-3.8
-5.4
CBS domain-containing protein
compare
MMJJ
_RS08250
-3.8
-9.6
hydrogenase maturation peptidase HycI
compare
MMJJ
_RS05535
-3.7
-15.9
hypothetical protein
compare
MMJJ
_RS07720
-3.7
-3.5
UPF0058 family protein
compare
MMJJ
_RS06875
-3.7
-4.2
hypothetical protein
compare
MMJJ
_RS01750
-3.7
-3.7
ferrous iron transport protein A
compare
MMJJ
_RS05650
-3.7
-4.7
formylmethanofuran dehydrogenase subunit B
compare
MMJJ
_RS06910
-3.7
-5.3
energy-converting NiFe hydrogenase A subunit EhaA
compare
MMJJ
_RS07350
-3.6
-4.3
4Fe-4S binding protein
compare
MMJJ
_RS07665
-3.6
-21.5
formate dehydrogenase subunit alpha
compare
MMJJ
_RS00570
-3.6
-2.4
ribonuclease P
compare
MMJJ
_RS00370
-3.6
-2.9
asparagine synthase (glutamine-hydrolyzing)
compare
MMJJ
_RS04800
-3.6
-9.1
2-phospho-L-lactate guanylyltransferase
compare
MMJJ
_RS05575
-3.6
-6.5
2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase
compare
MMJJ
_RS05610
-3.5
-6.3
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMJJ
_RS06695
-3.5
-4.0
amidohydrolase
compare
MMJJ
_RS08625
-3.5
-9.4
magnesium/cobalt transporter CorA
compare
MMJJ
_RS06725
-3.4
-15.8
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMJJ
_RS04475
-3.4
-5.3
3,4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMJJ
_RS07670
-3.4
-18.6
Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain
compare
MMJJ
_RS07785
-3.4
-4.3
fumarate reductase subunit A
compare
MMJJ
_RS03110
-3.4
-5.6
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase
compare
MMJJ
_RS08020
-3.3
-8.5
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS03150
-3.3
-9.1
2-phospho-L-lactate transferase
compare
MMJJ
_RS06390
-3.3
-3.3
NADPH-dependent F420 reductase
compare
MMJJ
_RS05260
-3.3
-7.0
ATP-grasp domain-containing protein
compare
MMJJ
_RS07705
-3.3
-5.1
GTP-binding protein EngB
compare
MMJJ
_RS05930
-3.3
-3.3
cell division protein SepF
compare
MMJJ
_RS06180
-3.3
-4.4
tryptophan--tRNA ligase
compare
MMJJ
_RS03190
-3.3
-3.8
phosphopyruvate hydratase
compare
MMJJ
_RS04685
-3.3
-12.6
carbamoyltransferase HypF
compare
MMJJ
_RS00125
-3.2
-3.7
KEOPS complex subunit Cgi121
compare
MMJJ
_RS06255
-3.2
-8.4
tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3
compare
MMJJ
_RS07655
-3.2
-14.8
hypothetical protein
compare
MMJJ
_RS07380
-3.2
-11.4
sulfide-dependent adenosine diphosphate thiazole synthase
compare
MMJJ
_RS06930
-3.1
-4.0
type II methionyl aminopeptidase
compare
MMJJ
_RS02090
-3.1
-7.2
tyramine--L-glutamate ligase
compare
MMJJ
_RS06915
-3.1
-15.5
helix-turn-helix domain-containing protein
compare
MMJJ
_RS03620
-3.1
-6.0
DUF2097 domain-containing protein
compare
MMJJ
_RS03820
-3.1
-5.8
hydrogenase formation protein HypD
compare
MMJJ
_RS07945
-3.1
-5.4
4Fe-4S binding protein
compare
MMJJ
_RS06110
-3.1
-3.5
bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC
compare
MMJJ
_RS08055
-3.1
-7.4
methanogenesis marker 14 protein
compare
MMJJ
_RS03865
-3.1
-2.6
phosphoribosyl-AMP cyclohydrolase
compare
MMJJ
_RS04155
-3.0
-8.5
hypothetical protein
compare
MMJJ
_RS01865
-3.0
-7.6
peptidyl-tRNA hydrolase Pth2
compare
MMJJ
_RS08005
-3.0
-16.8
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMJJ
_RS04970
-3.0
-2.4
DUF655 domain-containing protein
compare
MMJJ
_RS03670
-3.0
-5.4
precorrin-2 C(20)-methyltransferase
compare
MMJJ
_RS05620
-2.9
-6.6
CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein
compare
MMJJ
_RS04655
-2.9
-7.1
FAD-dependent oxidoreductase
compare
MMJJ
_RS00355
-2.9
-4.0
ribonuclease P protein component 4
compare
MMJJ
_RS00210
-2.9
-3.6
DUF530 family protein
compare
MMJJ
_RS05720
-2.8
-4.2
glutamine--fructose-6-phosphate transaminase (isomerizing)
compare
MMJJ
_RS08095
-2.8
-6.4
cobyric acid synthase CobQ
compare
MMJJ
_RS08340
-2.8
-5.0
archaeoflavoprotein AfpA
compare
MMJJ
_RS06805
-2.8
-4.5
monovalent cation/H+ antiporter subunit E
compare
MMJJ
_RS08080
-2.8
-10.2
TIGR00300 family protein
compare
MMJJ
_RS04675
-2.8
-6.9
thiamine pyrophosphate-binding protein
compare
MMJJ
_RS01415
-2.7
-3.7
beta-CASP ribonuclease aCPSF1
compare
MMJJ
_RS03065
-2.7
-12.2
CBS domain-containing protein
compare
MMJJ
_RS01755
-2.7
-3.5
ferrous iron transport protein B
compare
MMJJ
_RS04730
-2.7
-3.9
tyrosine decarboxylase MfnA
compare
MMJJ
_RS06155
-2.6
-6.8
phosphatidylglycerophosphatase A
compare
MMJJ
_RS04790
-2.6
-4.5
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMJJ
_RS04670
-2.6
-4.5
DUF2117 domain-containing protein
compare
MMJJ
_RS06785
-2.6
-7.2
RNA ligase partner protein
compare
MMJJ
_RS02275
-2.6
-7.0
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS04995
-2.6
-7.2
Tfx family DNA-binding protein
compare
MMJJ
_RS08330
-2.6
-3.1
SufD family Fe-S cluster assembly protein
compare
MMJJ
_RS07470
-2.6
-2.9
50S ribosome-binding GTPase
compare
MMJJ
_RS03270
-2.5
-2.7
ribosome biogenesis/translation initiation ATPase RLI
compare
MMJJ
_RS08840
-2.5
-4.8
calcium/sodium antiporter
compare
MMJJ
_RS05810
-2.5
-7.0
precorrin-4 C(11)-methyltransferase
compare
MMJJ
_RS04595
-2.5
-6.5
hypothetical protein
compare
MMJJ
_RS07410
-2.5
-4.3
methanogenesis marker protein Mmp4/MtxX
compare
MMJJ
_RS03295
-2.5
-15.3
PHP domain-containing protein
compare
MMJJ
_RS03830
-2.5
-9.2
CBS domain-containing protein
compare
MMJJ
_RS08000
-2.5
-9.9
HesA/MoeB/ThiF family protein
compare
MMJJ
_RS06185
-2.5
-6.6
cobalamin biosynthesis protein
compare
MMJJ
_RS04520
-2.5
-5.8
coenzyme F430 synthase
compare
MMJJ
_RS07360
-2.5
-2.1
TIGR00269 family protein
compare
MMJJ
_RS09175
-2.5
-2.2
anthranilate synthase component I
compare
MMJJ
_RS01360
-2.5
-3.3
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMJJ
_RS03815
-2.4
-2.5
nascent polypeptide-associated complex protein
compare
MMJJ
_RS03125
-2.4
-5.2
GMC oxidoreductase
compare
MMJJ
_RS06840
-2.4
-4.2
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS05590
-2.4
-2.2
homoserine dehydrogenase
compare
MMJJ
_RS05375
-2.4
-15.6
radical SAM protein
compare
MMJJ
_RS00475
-2.4
-2.6
bifunctional ornithine acetyltransferase/N-acetylglutamate synthase
compare
MMJJ
_RS05065
-2.4
-4.8
(4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase
compare
MMJJ
_RS03615
-2.4
-3.3
cobalt-precorrin-8 methylmutase
compare
MMJJ
_RS02935
-2.4
-4.5
DNA-directed RNA polymerase subunit E''
compare
MMJJ
_RS00215
-2.3
-2.7
CCA tRNA nucleotidyltransferase
compare
MMJJ
_RS03800
-2.3
-11.6
aldolase
compare
MMJJ
_RS07275
-2.3
-3.6
formate--phosphoribosylaminoimidazolecarboxamide ligase
compare
MMJJ
_RS03005
-2.3
-4.3
Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit
compare
MMJJ
_RS03630
-2.3
-11.2
AMP phosphorylase
compare
MMJJ
_RS06905
-2.3
-2.5
hypothetical protein
compare
MMJJ
_RS05360
-2.3
-6.8
nickel-responsive transcriptional regulator NikR
compare
MMJJ
_RS01355
-2.3
-4.4
UDP-N-acetyl-D-mannosamine dehydrogenase
compare
MMJJ
_RS06880
-2.3
-2.3
EhaG family protein
compare
MMJJ
_RS06730
-2.3
-6.7
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS07245
-2.3
-5.3
amidohydrolase family protein
compare
MMJJ
_RS07660
-2.3
-9.8
carbonic anhydrase
compare
MMJJ
_RS06705
-2.3
-5.7
bifunctional NADP phosphatase/NAD kinase
compare
MMJJ
_RS05415
-2.2
-2.2
hypothetical protein
compare
MMJJ
_RS08620
-2.2
-4.2
DUF373 family protein
compare
MMJJ
_RS06835
-2.2
-11.9
4Fe-4S binding protein
compare
MMJJ
_RS00600
-2.2
-3.3
hydroxymethylbilane synthase
compare
MMJJ
_RS00580
-2.2
-1.9
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG
compare
MMJJ
_RS00050
-2.2
-12.6
AAA family ATPase
compare
MMJJ
_RS01475
-2.2
-2.8
signal recognition particle-docking protein FtsY
compare
MMJJ
_RS05655
-2.2
-6.7
HisA/HisF family protein
compare
MMJJ
_RS00065
-2.2
-11.8
4Fe-4S dicluster domain-containing protein
compare
MMJJ
_RS06215
-2.2
-4.8
agmatinase
compare
MMJJ
_RS06220
-2.2
-5.1
polyamine aminopropyltransferase
compare
MMJJ
_RS04620
-2.2
-2.9
homocitrate synthase family protein
compare
MMJJ
_RS06375
-2.1
-4.3
UbiX family flavin prenyltransferase
compare
MMJJ
_RS00035
-2.1
-14.7
CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
compare
MMJJ
_RS07190
-2.1
-4.6
RtcB family protein
compare
MMJJ
_RS07155
-2.1
-9.5
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMJJ
_RS07355
-2.1
-4.9
MoaD/ThiS family protein
compare
MMJJ
_RS03115
-2.1
-8.7
sulfopyruvate decarboxylase subunit alpha
compare
MMJJ
_RS01345
-2.1
-4.4
(5-formylfuran-3-yl)methyl phosphate synthase
compare
MMJJ
_RS03785
-2.1
-3.3
hypothetical protein
compare
MMJJ
_RS00045
-2.1
-11.7
CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
compare
MMJJ
_RS08855
-2.1
-4.6
cyclic pyranopterin monophosphate synthase MoaC
compare
MMJJ
_RS06485
-2.1
-3.1
phosphoglycerate kinase
compare
MMJJ
_RS05190
-2.1
-8.8
gamma carbonic anhydrase family protein
compare
MMJJ
_RS00070
-2.0
-3.0
CooT family nickel-binding protein
compare
MMJJ
_RS08535
-2.0
-3.7
NOL1/NOP2/sun family putative RNA methylase
compare
MMJJ
_RS07635
-2.0
-12.8
response regulator transcription factor
compare
MMJJ
_RS00530
-2.0
-11.1
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS09190
-2.0
-2.7
tryptophan synthase subunit beta
compare
MMJJ
_RS04985
-2.0
-3.4
glutamyl-tRNA reductase
compare
MMJJ
_RS06050
-2.0
-10.9
molybdopterin molybdotransferase MoeA
compare
MMJJ
_RS00270
-2.0
-3.0
adenosylcobinamide-GDP ribazoletransferase
compare
MMJJ
_RS00075
-2.0
-10.0
AAA family ATPase
compare
MMJJ
_RS05295
-2.0
-7.6
cobyrinic acid a,c-diamide synthase
compare
MMJJ
_RS06175
-2.0
-2.5
DUF1743 domain-containing protein
compare
MMJJ
_RS04010
-2.0
-6.7
archaeal proteasome endopeptidase complex subunit alpha
compare
MMJJ
_RS00040
-2.0
-9.2
CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
compare
MMJJ
_RS07345
-2.0
-4.9
homocysteine biosynthesis protein
compare
MMJJ
_RS04615
-1.9
-5.3
methanogenesis marker 3 protein
compare
MMJJ
_RS02200
-1.9
-9.6
chorismate pyruvate-lyase family protein
compare
MMJJ
_RS00520
-1.9
-4.8
PDGLE domain-containing protein
compare
MMJJ
_RS07995
-1.9
-5.9
molybdenum cofactor biosynthesis protein MoaE
compare
MMJJ
_RS00060
-1.9
-13.3
acetyl-CoA decarbonylase/synthase complex subunit gamma
compare
MMJJ
_RS00425
-1.9
-3.3
hypothetical protein
compare
MMJJ
_RS00080
-1.9
-13.1
DUF166 domain-containing protein
compare
MMJJ
_RS07640
-1.9
-15.7
cache domain-containing protein
compare
MMJJ
_RS03160
-1.9
-12.4
winged helix-turn-helix transcriptional regulator
compare
MMJJ
_RS06240
-1.9
-3.1
dihydropteroate synthase-like protein
compare
MMJJ
_RS01565
-1.9
-5.7
TIGR00267 family protein
compare
MMJJ
_RS00450
-1.9
-1.5
DUF126 domain-containing protein
compare
MMJJ
_RS09130
-1.9
-1.6
NFYB/HAP3 family transcription factor subunit
compare
MMJJ
_RS04110
-1.9
-4.8
hypothetical protein
compare
MMJJ
_RS02055
-1.8
-9.7
GTP 3',8-cyclase MoaA
compare
MMJJ
_RS05380
-1.8
-1.9
hypothetical protein
compare
MMJJ
_RS08480
-1.8
-7.7
hydroxyethylthiazole kinase
compare
MMJJ
_RS07650
-1.8
-12.6
formate/nitrite transporter family protein
compare
MMJJ
_RS00560
-1.8
-3.7
homoisocitrate dehydrogenase
compare
MMJJ
_RS04975
-1.8
-2.1
glycosyltransferase family 4 protein
compare
MMJJ
_RS07715
-1.8
-2.9
UbiD family decarboxylase
compare
MMJJ
_RS07505
-1.8
-1.3
DNA-directed RNA polymerase subunit K
compare
MMJJ
_RS00265
-1.8
-5.7
TIGR02253 family HAD-type hydrolase
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments