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Experiment set3IT047 for
Methanococcus maripaludis JJ
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formate McAA riboflavin dropout
200 most detrimental genes:
gene
name
fitness
t score
description
MMJJ
_RS04415
+2.5
10.8
hypothetical protein
compare
MMJJ
_RS08130
+1.5
1.7
translation initiation factor IF-2 subunit gamma
compare
MMJJ
_RS04005
+0.8
6.1
acetate--CoA ligase family protein
compare
MMJJ
_RS08935
+0.8
1.4
TIGR00288 family NYN domain-containing protein
compare
MMJJ
_RS01785
+0.6
1.1
50S ribosomal protein L14e
compare
MMJJ
_RS04955
+0.6
3.5
tRNA pseudouridine(54/55) synthase Pus10
compare
MMJJ
_RS06680
+0.6
3.6
DUF366 family protein
compare
MMJJ
_RS06745
+0.6
3.3
energy-coupling factor ABC transporter permease
compare
MMJJ
_RS06675
+0.6
4.2
TIGR01212 family radical SAM protein
compare
MMJJ
_RS07920
+0.5
4.1
6-carboxytetrahydropterin synthase QueD
compare
MMJJ
_RS06190
+0.5
4.2
7-cyano-7-deazaguanine synthase
compare
MMJJ
_RS07185
+0.5
1.5
DUF371 domain-containing protein
compare
MMJJ
_RS07225
+0.5
3.6
coenzyme F420 hydrogenase subunit gamma
compare
MMJJ
_RS07795
+0.5
2.5
cupin domain-containing protein
compare
MMJJ
_RS07220
+0.5
4.0
coenzyme F420 hydrogenase subunit beta
compare
MMJJ
_RS01530
+0.5
1.5
YwbE family protein
compare
MMJJ
_RS06735
+0.5
2.9
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS07915
+0.5
2.7
CBS domain-containing protein
compare
MMJJ
_RS06385
+0.5
2.3
hypothetical protein
compare
MMJJ
_RS06740
+0.5
3.0
energy-coupling factor ABC transporter substrate-binding protein
compare
MMJJ
_RS07025
+0.5
2.8
tRNA (cytidine(56)-2'-O)-methyltransferase
compare
MMJJ
_RS06085
+0.5
2.0
proteasome assembly chaperone family protein
compare
MMJJ
_RS07240
+0.5
3.9
MBL fold metallo-hydrolase
compare
MMJJ
_RS06505
+0.5
1.8
prephenate dehydratase
compare
MMJJ
_RS07270
+0.5
2.8
ribonuclease HII
compare
MMJJ
_RS06205
+0.5
3.4
EamA family transporter
compare
MMJJ
_RS06440
+0.5
3.4
DUF4870 domain-containing protein
compare
MMJJ
_RS07235
+0.4
3.8
coenzyme F420 hydrogenase subunit alpha
compare
MMJJ
_RS05975
+0.4
3.2
sulfurtransferase TusA family protein
compare
MMJJ
_RS06515
+0.4
3.3
ribonuclease III
compare
MMJJ
_RS01395
+0.4
2.6
DUF1894 domain-containing protein
compare
MMJJ
_RS05040
+0.4
3.0
7-carboxy-7-deazaguanine synthase QueE
compare
MMJJ
_RS06460
+0.4
2.8
cytochrome c
compare
MMJJ
_RS03350
+0.4
1.2
hypothetical protein
compare
MMJJ
_RS05530
+0.4
1.7
roadblock/LC7 domain-containing protein
compare
MMJJ
_RS06640
+0.4
3.2
YfcE family phosphodiesterase
compare
MMJJ
_RS08830
+0.4
1.9
hypothetical protein
compare
MMJJ
_RS04105
+0.4
3.1
prepilin peptidase
compare
MMJJ
_RS08100
+0.4
2.2
hypothetical protein
compare
MMJJ
_RS03725
+0.4
1.2
sulfurtransferase TusA family protein
compare
MMJJ
_RS07210
+0.4
2.8
AmmeMemoRadiSam system protein B
compare
MMJJ
_RS08165
+0.4
2.2
thermonuclease family protein
compare
MMJJ
_RS06500
+0.4
2.3
class I SAM-dependent methyltransferase
compare
MMJJ
_RS01790
+0.4
2.7
pyridoxamine 5'-phosphate oxidase family protein
compare
MMJJ
_RS04610
+0.4
1.7
ribosome assembly RNA-binding protein YhbY
compare
MMJJ
_RS06430
+0.4
2.1
haloacid dehalogenase
compare
MMJJ
_RS04345
+0.4
1.2
DUF2080 family transposase-associated protein
compare
MMJJ
_RS07765
+0.4
2.0
DMT family protein
compare
MMJJ
_RS06540
+0.4
1.3
DUF2120 domain-containing protein
compare
MMJJ
_RS07450
+0.4
1.5
hypothetical protein
compare
MMJJ
_RS06585
+0.4
2.4
alanine racemase
compare
MMJJ
_RS00115
+0.4
1.4
hypothetical protein
compare
MMJJ
_RS01070
+0.4
0.7
PadR family transcriptional regulator
compare
MMJJ
_RS06770
+0.4
2.8
hypothetical protein
compare
MMJJ
_RS06960
+0.3
3.0
CAP domain-containing protein
compare
MMJJ
_RS06520
+0.3
2.6
TldD/PmbA family protein
compare
MMJJ
_RS07495
+0.3
1.8
4Fe-4S binding protein
compare
MMJJ
_RS06790
+0.3
2.7
nucleotidyltransferase family protein
compare
MMJJ
_RS07610
+0.3
2.6
DUF2119 domain-containing protein
compare
MMJJ
_RS07835
+0.3
2.3
UPF0489 family protein
compare
MMJJ
_RS06235
+0.3
2.8
IGHMBP2 family helicase
compare
MMJJ
_RS08305
+0.3
1.9
peroxiredoxin
compare
MMJJ
_RS07890
+0.3
1.9
pyrimidine dimer DNA glycosylase/endonuclease V
compare
MMJJ
_RS03375
+0.3
1.8
hypothetical protein
compare
MMJJ
_RS07905
+0.3
2.3
DUF89 domain-containing protein
compare
MMJJ
_RS01010
+0.3
3.0
right-handed parallel beta-helix repeat-containing protein
compare
MMJJ
_RS07365
+0.3
2.3
CatB-related O-acetyltransferase
compare
MMJJ
_RS07815
+0.3
2.3
2-oxoacid:acceptor oxidoreductase family protein
compare
MMJJ
_RS07810
+0.3
2.1
3-methyl-2-oxobutanoate dehydrogenase subunit VorB
compare
MMJJ
_RS06120
+0.3
2.1
DUF4013 domain-containing protein
compare
MMJJ
_RS07205
+0.3
1.3
MTH895/ArsE family thioredoxin-like protein
compare
MMJJ
_RS08410
+0.3
0.9
CBS domain-containing protein
compare
MMJJ
_RS04545
+0.3
1.4
PadR family transcriptional regulator
compare
MMJJ
_RS06800
+0.3
1.9
prefoldin subunit alpha
compare
MMJJ
_RS04350
+0.3
1.4
hypothetical protein
compare
MMJJ
_RS07985
+0.3
1.6
hypothetical protein
compare
MMJJ
_RS06275
+0.3
1.2
hypothetical protein
compare
MMJJ
_RS06470
+0.3
2.1
tripartite tricarboxylate transporter permease
compare
MMJJ
_RS07480
+0.3
2.3
FAD-dependent oxidoreductase
compare
MMJJ
_RS06580
+0.3
2.3
alanine dehydrogenase
compare
MMJJ
_RS06950
+0.3
2.1
4-demethylwyosine synthase TYW1
compare
MMJJ
_RS06590
+0.3
2.2
sodium:alanine symporter family protein
compare
MMJJ
_RS07740
+0.3
2.0
DUF2334 domain-containing protein
compare
MMJJ
_RS04390
+0.3
2.1
rhomboid family intramembrane serine protease
compare
MMJJ
_RS06535
+0.3
2.3
UPF0104 family protein
compare
MMJJ
_RS05335
+0.3
1.5
heavy metal-binding domain-containing protein
compare
MMJJ
_RS03575
+0.3
1.5
NUDIX hydrolase
compare
MMJJ
_RS06710
+0.3
2.1
TldD/PmbA family protein
compare
MMJJ
_RS00745
+0.3
1.0
hypothetical protein
compare
MMJJ
_RS01855
+0.3
1.9
MBL fold metallo-hydrolase
compare
MMJJ
_RS05355
+0.3
1.8
DUF2121 domain-containing protein
compare
MMJJ
_RS06550
+0.3
2.0
ABC transporter permease
compare
MMJJ
_RS04635
+0.3
1.2
DUF367 family protein
compare
MMJJ
_RS04525
+0.3
1.1
hypothetical protein
compare
MMJJ
_RS06090
+0.3
1.8
hypothetical protein
compare
MMJJ
_RS06765
+0.3
2.1
hypothetical protein
compare
MMJJ
_RS06445
+0.3
2.3
hypothetical protein
compare
MMJJ
_RS04300
+0.3
1.7
hypothetical protein
compare
MMJJ
_RS02665
+0.3
0.6
methyl-accepting chemotaxis protein
compare
MMJJ
_RS06685
+0.3
2.2
S-layer protein
compare
MMJJ
_RS04215
+0.3
2.1
DMT family transporter
compare
MMJJ
_RS08455
+0.3
1.1
tetratricopeptide repeat protein
compare
MMJJ
_RS05500
+0.3
2.3
hypothetical protein
compare
MMJJ
_RS01970
+0.3
1.2
hypothetical protein
compare
MMJJ
_RS06810
+0.3
1.9
L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha
compare
MMJJ
_RS03835
+0.2
1.1
DUF504 domain-containing protein
compare
MMJJ
_RS04420
+0.2
2.0
type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family
compare
MMJJ
_RS00155
+0.2
2.1
DUF2193 domain-containing protein
compare
MMJJ
_RS08015
+0.2
1.2
HAD family hydrolase
compare
MMJJ
_RS05340
+0.2
1.9
AAA family ATPase
compare
MMJJ
_RS07010
+0.2
1.3
preprotein translocase subunit Sec61beta
compare
MMJJ
_RS08370
+0.2
1.4
hypothetical protein
compare
MMJJ
_RS02270
+0.2
1.2
HEPN domain-containing protein
compare
MMJJ
_RS09120
+0.2
0.3
aspartate kinase
compare
MMJJ
_RS03445
+0.2
1.2
hypothetical protein
compare
MMJJ
_RS05685
+0.2
1.3
class III signal peptide-containing protein
compare
MMJJ
_RS07230
+0.2
1.5
coenzyme F420-reducing hydrogenase, FrhD protein
compare
MMJJ
_RS03345
+0.2
1.4
hypothetical protein
compare
MMJJ
_RS03805
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS05700
+0.2
1.5
metallophosphoesterase
compare
MMJJ
_RS09360
+0.2
1.4
hypothetical protein
compare
MMJJ
_RS07800
+0.2
1.9
AMP-binding protein
compare
MMJJ
_RS07445
+0.2
1.5
RlmF-related methyltransferase
compare
MMJJ
_RS07260
+0.2
1.4
PspC domain-containing protein
compare
MMJJ
_RS05900
+0.2
1.8
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS09380
+0.2
0.8
hypothetical protein
compare
MMJJ
_RS05510
+0.2
1.6
archaellum operon transcriptional activator EarA family protein
compare
MMJJ
_RS06455
+0.2
1.6
YeeE/YedE family protein
compare
MMJJ
_RS02285
+0.2
0.7
class III signal peptide-containing protein
compare
MMJJ
_RS01945
+0.2
1.3
cell division ATPase MinD
compare
MMJJ
_RS09020
+0.2
1.1
hypothetical protein
compare
MMJJ
_RS01825
+0.2
1.0
DNA repair and recombination protein RadB
compare
MMJJ
_RS01385
+0.2
1.6
PadR family transcriptional regulator
compare
MMJJ
_RS05350
+0.2
0.9
DUF192 domain-containing protein
compare
MMJJ
_RS03515
+0.2
1.2
GPR1/FUN34/YaaH family transporter
compare
MMJJ
_RS07855
+0.2
1.5
YkgJ family cysteine cluster protein
compare
MMJJ
_RS08380
+0.2
0.7
hypothetical protein
compare
MMJJ
_RS07820
+0.2
1.6
bifunctional hexulose-6-phosphate synthase/ribonuclease regulator
compare
MMJJ
_RS05410
+0.2
1.4
RecB-family nuclease
compare
MMJJ
_RS07695
+0.2
1.7
glycoside hydrolase family 15 protein
compare
MMJJ
_RS07200
+0.2
1.7
MFS transporter
compare
MMJJ
_RS05660
+0.2
1.3
sulfopyruvate decarboxylase subunit beta
compare
MMJJ
_RS00885
+0.2
1.2
coenzyme F420-reducing hydrogenase, FrhD protein
compare
MMJJ
_RS01800
+0.2
1.4
ADP-ribosylglycohydrolase family protein
compare
MMJJ
_RS08515
+0.2
1.0
secondary thiamine-phosphate synthase enzyme YjbQ
compare
MMJJ
_RS06280
+0.2
1.5
hypothetical protein
compare
MMJJ
_RS08670
+0.2
1.5
phosphate signaling complex protein PhoU
compare
MMJJ
_RS09205
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS04120
+0.2
1.2
amino acid ABC transporter ATP-binding protein
compare
MMJJ
_RS08350
+0.2
1.7
heavy metal translocating P-type ATPase
compare
MMJJ
_RS08285
+0.2
1.5
class I SAM-dependent methyltransferase
compare
MMJJ
_RS07215
+0.2
1.7
TIGR00341 family protein
compare
MMJJ
_RS05985
+0.2
1.3
ABC transporter substrate-binding protein
compare
MMJJ
_RS00630
+0.2
1.3
betaine/proline/choline family ABC transporter ATP-binding protein
compare
MMJJ
_RS07750
+0.2
0.4
class III signal peptide-containing protein
compare
MMJJ
_RS08375
+0.2
1.4
ferritin
compare
MMJJ
_RS01955
+0.2
1.5
hypothetical protein
compare
MMJJ
_RS09230
+0.2
0.6
hypothetical protein
compare
MMJJ
_RS05200
+0.2
1.5
TIGR04013 family B12-binding domain/radical SAM domain-containing protein
compare
MMJJ
_RS04850
+0.2
1.1
energy-coupling factor transporter transmembrane protein EcfT
compare
MMJJ
_RS01430
+0.2
1.2
hypothetical protein
compare
MMJJ
_RS01835
+0.2
1.4
tRNA pseudouridine(13) synthase TruD
compare
MMJJ
_RS05235
+0.2
1.6
Flp pilus assembly complex ATPase component TadA
compare
MMJJ
_RS05690
+0.2
1.6
hypothetical protein
compare
MMJJ
_RS07385
+0.2
1.3
ribosomal protein S18-alanine N-acetyltransferase
compare
MMJJ
_RS05605
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS05990
+0.2
1.0
phosphatase PAP2 family protein
compare
MMJJ
_RS05980
+0.2
1.1
DUF5400 domain-containing protein
compare
MMJJ
_RS05750
+0.2
1.3
flagellar accessory protein FlaH
compare
MMJJ
_RS06210
+0.2
0.8
hypothetical protein
compare
MMJJ
_RS06080
+0.2
1.2
serine/threonine protein kinase
compare
MMJJ
_RS03730
+0.2
0.7
SWIM zinc finger family protein
compare
MMJJ
_RS08215
+0.2
1.1
radical SAM protein
compare
MMJJ
_RS02180
+0.2
0.8
DHH family phosphoesterase
compare
MMJJ
_RS02265
+0.2
1.3
hypothetical protein
compare
MMJJ
_RS05520
+0.2
1.3
H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein
compare
MMJJ
_RS03395
+0.2
0.5
hypothetical protein
compare
MMJJ
_RS08685
+0.2
1.1
phosphate ABC transporter permease subunit PstC
compare
MMJJ
_RS06495
+0.2
0.5
hypothetical protein
compare
MMJJ
_RS05785
+0.2
1.1
flagellin
compare
MMJJ
_RS07885
+0.2
1.1
NERD domain-containing protein
compare
MMJJ
_RS07255
+0.2
1.4
hypothetical protein
compare
MMJJ
_RS09105
+0.2
1.2
AI-2E family transporter
compare
MMJJ
_RS02965
+0.2
0.8
RimK-like ATPgrasp N-terminal domain-containing protein
compare
MMJJ
_RS04825
+0.2
1.3
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
compare
MMJJ
_RS03595
+0.2
0.6
hypothetical protein
compare
MMJJ
_RS08160
+0.2
1.1
tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO
compare
MMJJ
_RS00740
+0.2
0.9
hypothetical protein
compare
MMJJ
_RS06055
+0.2
1.0
S-methyl-5-thioribose-1-phosphate isomerase
compare
MMJJ
_RS05365
+0.2
0.7
DUF2798 domain-containing protein
compare
MMJJ
_RS07680
+0.1
1.0
glucose-6-phosphate isomerase
compare
MMJJ
_RS08485
+0.1
0.7
Lrp/AsnC family transcriptional regulator
compare
MMJJ
_RS03040
+0.1
1.1
lactate utilization protein
compare
MMJJ
_RS08395
+0.1
1.2
CoB--CoM heterodisulfide reductase subunit B
compare
MMJJ
_RS01715
+0.1
0.9
winged helix-turn-helix domain-containing protein
compare
MMJJ
_RS06555
+0.1
1.2
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS08210
+0.1
1.4
hypothetical protein
compare
MMJJ
_RS00405
+0.1
0.8
flavodoxin family protein
compare
MMJJ
_RS06450
+0.1
1.0
DUF3343 domain-containing protein
compare
MMJJ
_RS03070
+0.1
0.6
MetS family NSS transporter small subunit
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments