Experiment set3IT046 for Sinorhizobium meliloti 1021

Compare to:

LB with Sisomicin sulfate salt 0.004 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
SMc02112 +3.1 21.1 hypothetical protein compare
SMc00647 +2.7 10.2 ribosomal large subunit pseudouridine synthase compare
SMc00761 +2.3 18.1 oxidoreductase compare
SMc04454 +2.0 9.3 ABC transporter ATP-binding protein compare
SM_b20143 +1.8 1.9 oligopeptide ABC transporter permease compare
SMc00522 +1.8 11.6 ATP-dependent RNA helicase compare
SMc03069 +1.8 6.0 6-phosphogluconolactonase compare
SMc00150 +1.7 15.4 hypothetical protein compare
SMc03900 +1.7 13.8 cyclic beta-1,2-glucan ABc transporter compare
SMc01907 +1.7 12.0 hypothetical protein compare
SMc00131 +1.7 11.5 transcriptional regulator compare
SMc00414 +1.6 10.3 hypothetical protein compare
SMc03826 +1.5 3.2 argininosuccinate synthase compare
SMa2020 +1.5 7.6 Transcriptional regulator compare
SMc03053 +1.5 1.2 flagellar biosynthesis protein FliQ compare
SMc02137 +1.5 3.7 ornithine carbamoyltransferase compare
SMc00495 +1.5 6.5 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc02577 +1.4 7.1 ATP-dependent protease ATP-binding subunit HslU conserved
SMc04246 +1.4 2.0 transmembrane signal peptide protein compare
SMc02858 +1.4 0.8 chaperone protein DnaJ compare
SMc02121 +1.4 1.3 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, ATPase component (from data) compare
SM_b20746 +1.4 1.4 hypothetical protein compare
SMc04382 +1.3 12.3 beta-(1,2)-glucan production associated transmembrane protein compare
SMc02615 +1.3 2.3 signal peptide protein compare
SMc02906 +1.3 1.4 hypothetical protein compare
SMc00458 +1.3 9.6 transcriptional regulator compare
SMc02778 +1.2 1.5 hydroxyacid aldolase compare
SM_b21183 +1.2 7.8 molecular chaperone HtpG compare
SMc02503 +1.2 7.2 hypothetical protein compare
SMc01991 +1.2 1.5 short chain dehydrogenase compare
SMc00727 +1.2 5.8 3-hydroxybutyryl-CoA dehydrogenase compare
SMc00321 +1.1 5.0 tRNA pseudouridine synthase B compare
SMa1099 +1.1 1.8 CycB1 cytochrome c-552 precursor compare
SMc00826 +1.1 3.8 16S ribosomal RNA methyltransferase RsmE compare
SMc00247 +1.1 5.5 phosphatidylcholine synthase compare
SMc04000 +1.1 1.7 hypothetical protein compare
SMc03780 +1.1 4.0 hypothetical protein compare
SM_b21084 +1.1 2.3 hypothetical protein compare
SMc01099 +1.1 2.2 tRNA pseudouridine synthase A compare
SMa1639 +1.1 1.1 hypothetical protein compare
SM_b20882 +1.0 2.1 hypothetical protein compare
SMc01103 +1.0 4.0 Ribokinase (EC 2.7.1.15) (from data) compare
SM_b20294 +1.0 0.9 transcriptional regulator NanR compare
SMc01942 +1.0 1.8 urease accessory protein compare
SMc02755 +1.0 4.2 S-adenosyl-L-homocysteine hydrolase compare
SM_b20616 +1.0 1.3 thiamine biosynthesis oxidoreductase compare
SMc02238 +1.0 1.6 hypothetical protein compare
SMc01124 +1.0 6.4 PII uridylyl-transferase compare
SMc04327 +1.0 1.0 hypothetical protein compare
SM_b21580 +1.0 1.2 hypothetical protein compare
SMa0874 +1.0 1.6 NodN dehydratase compare
SMa1002 +1.0 1.5 hypothetical protein compare
SMc02975 +0.9 4.0 phosphoenolpyruvate carboxykinase regulator transcription regulator protein compare
SM_b21177 +0.9 4.0 phosphate uptake ABC transporter ATP-binding protein compare
SMc00337 +0.9 1.2 hypothetical protein compare
SM_b21397 +0.9 2.1 hypothetical protein compare
SMc00505 +0.9 1.3 hypothetical protein compare
SMc00711 +0.9 2.3 cyclohexadienyl dehydrogenase compare
SMc02765 +0.9 5.4 tryptophan synthase subunit alpha compare
SMc01363 +0.9 0.9 hypothetical protein compare
SMc02343 +0.9 2.2 transport transmembrane protein compare
SMa0878 +0.9 2.6 glucosamine--fructose-6-phosphate aminotransferase compare
SMc03899 +0.9 0.8 hypothetical protein compare
SMc04001 +0.9 1.0 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc04235 +0.9 3.8 tRNA-dihydrouridine synthase A compare
SM_b21494 +0.9 4.0 ornithine cyclodeaminase compare
SMc01273 +0.8 6.4 S-formylglutathione hydrolase compare
SMa1400 +0.8 2.5 acyl-CoA dehydrogenase compare
SMc02846 +0.8 3.2 sugar kinase compare
SM_b20703 +0.8 1.4 hypothetical protein compare
SMc00132 +0.8 2.6 hypothetical protein compare
SMc00064 +0.8 2.1 hypothetical protein compare
SMc01229 +0.8 2.1 acetyltransferase compare
SMa0886 +0.8 0.9 hypothetical protein compare
SM_b20690 +0.8 1.6 hypothetical protein compare
SM_b21633 +0.8 0.9 enoyl-CoA hydratase compare
SM_b21266 +0.8 4.0 hypothetical protein compare
SMc02558 +0.8 2.8 hypothetical protein compare
SMc04428 +0.8 2.6 hypothetical protein compare
SMa0518 +0.8 2.3 hypothetical protein compare
SMc00949 +0.8 3.2 hypothetical protein compare
SMc01097 +0.8 1.7 hypothetical protein compare
SMc00973 +0.8 1.5 hypothetical protein compare
SMc00187 +0.8 1.9 ubiquinol-cytochrome C reductase iron-sulfur subunit protein compare
SMa0326 +0.8 1.7 short chain alcohol dehydrogenase-related dehydrogenase compare
SMc00129 +0.8 4.3 sensor histidine kinase compare
SMc02287 +0.8 2.3 DNA-invertase compare
SMc03969 +0.8 2.8 hypothetical protein compare
SMc00805 +0.8 2.0 hypothetical protein compare
SM_b20571 +0.8 2.4 aliphatic sulfonate ABC transporter permease compare
SMc01908 +0.8 4.0 transcriptional regulator compare
SM_b20350 +0.8 2.4 hypothetical protein compare
SMc03963 +0.8 3.6 sulfolipid biosynthesis protein compare
SMa0674 +0.8 1.1 hypothetical protein compare
SMc02716 +0.8 2.0 hypothetical protein compare
SMc00351 +0.8 1.1 hypothetical protein compare
SMc02980 +0.7 0.9 hypothetical protein compare
SM_b20884 +0.7 1.4 hypothetical protein compare
SM_b21253 +0.7 2.9 hypothetical protein compare
SMc02766 +0.7 5.2 tryptophan synthase subunit beta compare
SM_b20722 +0.7 2.4 two-component response regulator protein compare
SMc03999 +0.7 1.9 hypothetical protein compare
SM_b20307 +0.7 0.6 dihydroxyacetone kinase compare
SMc03795 +0.7 0.6 isopropylmalate isomerase small subunit compare
SMa0659 +0.7 1.3 cytochrome c binding protein, carboxyl terminus compare
SM_b20400 +0.7 1.3 hypothetical protein compare
SMc01698 +0.7 3.0 oxidoreductase compare
SM_b21343 +0.7 1.5 sugar uptake ABC transporter permease compare
SMc03863 +0.7 2.0 50S ribosomal protein L19 compare
SMa1227 +0.7 4.0 response regulator FixJ compare
SM_b21176 +0.7 2.8 phosphate uptake ABC transporter substrate-binding protein precursor compare
SMc00431 +0.7 2.3 hypothetical protein compare
SM_b21631 +0.7 4.6 carboxynorspermidine decarboxylase compare
SMc00555 +0.7 0.9 colicin V production transmembrane protein compare
SMa0643 +0.7 0.9 transposase compare
SMc00019 +0.7 1.7 hypothetical protein compare
SMc02241 +0.7 2.8 hypothetical protein compare
SMc02164 +0.7 1.3 fructokinase compare
SM_b20255 +0.7 2.1 hypothetical protein compare
SM_b20760 +0.7 0.9 carbon-phosphorus lyase compare
SM_b20935 +0.7 2.0 transcriptional regulator compare
SMc00421 +0.7 3.1 O-acetylserine sulfhydrylase A compare
SMc00605 +0.7 1.4 hypothetical protein compare
SM_b21487 +0.7 4.0 cytochrome o ubiquinol oxidase subunit II compare
SMc03052 +0.7 2.6 flagellar basal body rod modification protein compare
SMc00976 +0.7 1.7 enoyl-CoA hydratase compare
SMc02727 +0.7 1.7 hypothetical protein compare
SMa0314 +0.7 1.5 hypothetical protein compare
SM_b22023 +0.6 1.1 molecular chaperone GroES compare
SM_b21493 +0.6 2.1 AsnC family transcriptional regulator compare
SM_b21475 +0.6 1.2 hypothetical protein compare
SM_b20176 +0.6 1.5 hypothetical protein compare
SMc01660 +0.6 1.6 hypothetical protein compare
SM_b21009 +0.6 4.0 Glycerol kinase (EC 2.7.1.30) (from data) compare
SMc02976 +0.6 1.8 transcriptional regulator compare
SMc02901 +0.6 0.5 hypothetical protein compare
SMc04264 +0.6 1.2 transcriptional regulator compare
SMa1174 +0.6 1.0 hypothetical protein compare
SM_b22005 +0.6 0.9 hypothetical protein compare
SMc03072 +0.6 0.4 hypothetical protein compare
SMc01026 +0.6 1.2 hypothetical protein compare
SM_b20593 +0.6 2.0 hypothetical protein compare
SMc01107 +0.6 3.5 hypothetical protein compare
SMc02057 +0.6 3.4 preprotein translocase subunit SecD/SecF compare
SM_b21533 +0.6 2.8 GntR family transcriptional regulator compare
SMc02495 +0.6 0.8 translaldolase compare
SMc02354 +0.6 1.2 hypothetical protein compare
SMc03176 +0.6 1.9 hypothetical protein compare
SMa1770 +0.6 0.7 hypothetical protein compare
SMa0341 +0.6 1.1 hypothetical protein compare
SMc04088 +0.6 3.1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
SMc01606 +0.6 2.7 permease compare
SMc03184 +0.6 0.7 PH adaptation potassium efflux system G transmembrane protein compare
SMc00770 +0.6 2.9 putrescine-binding periplasmic protein compare
SMc01951 +0.6 2.5 high-affinity branched-chain amino acid ABC transporter permease compare
SMc00648 +0.6 2.1 hypothetical protein compare
SMc00079 +0.6 2.7 hypothetical protein compare
SM_b20162 +0.6 2.5 transcriptional regulator compare
SMc00771 +0.6 2.8 putrescine ABC transporter ATP-binding protein compare
SMa0838 +0.6 1.5 SyrA protein involved in EPS production compare
SMa0244 +0.6 2.1 Dehydrogenase, FAD-dependent compare
SMc04383 +0.6 2.7 putative hydrolase, required for lysine catabolism (from data) compare
SMc03835 +0.6 1.2 2'-5' RNA ligase compare
SMc02271 +0.6 4.0 ribitol type dehydrogenase compare
SMc01669 +0.6 1.6 enoyl-CoA hydratase compare
SMc02684 +0.6 2.6 hydrolase/peptidase compare
SMc03006 +0.6 0.6 chemotaxis regulator protein compare
SMc00012 +0.6 0.7 cytochrome C oxidase assembly protein compare
SMc01573 +0.6 0.9 hypothetical protein compare
SMc00171 +0.6 2.7 hypothetical protein compare
SMc00821 +0.6 0.6 hypothetical protein compare
SMc02941 +0.6 1.3 hypothetical protein compare
SM_b21441 +0.5 0.8 inosine-5'-monophosphate dehydrogenase compare
SMc03878 +0.5 1.2 acetoacetyl-CoA reductase compare
SMc01120 +0.5 1.6 hypothetical protein compare
SMc00993 +0.5 2.3 phosphoribosylamine--glycine ligase compare
SM_b21587 +0.5 1.9 sugar uptake ABC transporter substrate-binding protein precursor compare
SMc02821 +0.5 2.1 hypothetical protein compare
SM_b20282 +0.5 0.9 spermidine/putrescine ABC transporter permease compare
SM_b20209 +0.5 0.9 hypothetical protein compare
SM_b20927 +0.5 2.5 hypothetical protein compare
SMc00772 +0.5 3.8 putrescine ABC transporter permease compare
SMc01826 +0.5 1.0 ABC transporter permease compare
SMc00009 +0.5 2.0 cytochrome C oxidase subunit II protein compare
SMc00998 +0.5 3.3 signal peptide protein compare
SMa1979 +0.5 1.7 LysR family transcriptional regulator compare
SMc03038 +0.5 1.5 flagellin B protein compare
SM_b21480 +0.5 0.6 hypothetical protein compare
SMa0835 +0.5 2.5 hypothetical protein compare
SMc00576 +0.5 1.5 hypothetical protein compare
SMc01004 +0.5 2.3 phosphoribosyl-AMP cyclohydrolase compare
SM_b21495 +0.5 1.5 protease compare
SM_b20953 +0.5 0.6 hypothetical protein compare
SMc02825 +0.5 1.4 aminopeptidase compare
SMc00600 +0.5 1.5 molybdopterin MPT converting factor subunit 1 compare
SMa1229 +0.5 3.1 FixL oxygen regulated histidine kinase compare
SM_b21264 +0.5 3.5 hypothetical protein compare
SMc04189 +0.5 1.6 hypothetical protein compare
SMa1149 +0.5 1.8 hypothetical protein compare
SM_b20128 +0.5 1.4 deaminase compare


Specific Phenotypes

For 11 genes in this experiment

For stress Sisomicin sulfate salt in Sinorhizobium meliloti 1021

For stress Sisomicin sulfate salt across organisms