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Experiment set3IT045 for
Methanococcus maripaludis JJ
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formate McAA thiamine dropout
200 most important genes:
gene
name
fitness
t score
description
MMJJ
_RS01935
-5.0
-4.8
O-phosphoseryl-tRNA(Sec) selenium transferase
compare
MMJJ
_RS06390
-4.8
-2.5
NADPH-dependent F420 reductase
compare
MMJJ
_RS03270
-4.8
-3.2
ribosome biogenesis/translation initiation ATPase RLI
compare
MMJJ
_RS06860
-4.7
-5.6
hypothetical protein
compare
MMJJ
_RS00275
-4.5
-3.5
coenzyme F420-0:L-glutamate ligase
compare
MMJJ
_RS02920
-4.4
-3.2
30S ribosomal protein S27ae
compare
MMJJ
_RS00235
-4.4
-22.2
hypothetical protein
compare
MMJJ
_RS05650
-4.2
-4.1
formylmethanofuran dehydrogenase subunit B
compare
MMJJ
_RS05450
-4.2
-18.8
TIGR03576 family pyridoxal phosphate-dependent enzyme
compare
MMJJ
_RS03580
-4.2
-4.3
TIGR00303 family protein
compare
MMJJ
_RS07950
-4.1
-4.5
4Fe-4S binding protein
compare
MMJJ
_RS04200
-4.0
-8.3
triphosphoribosyl-dephospho-CoA synthase
compare
MMJJ
_RS05070
-4.0
-2.9
DNA primase catalytic subunit PriS
compare
MMJJ
_RS07665
-3.9
-22.8
formate dehydrogenase subunit alpha
compare
MMJJ
_RS01750
-3.9
-3.5
ferrous iron transport protein A
compare
MMJJ
_RS05620
-3.8
-5.2
CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein
compare
MMJJ
_RS06875
-3.8
-4.0
hypothetical protein
compare
MMJJ
_RS01870
-3.8
-2.7
methanogenesis marker 15 protein
compare
MMJJ
_RS06805
-3.8
-3.6
monovalent cation/H+ antiporter subunit E
compare
MMJJ
_RS01755
-3.8
-2.6
ferrous iron transport protein B
compare
MMJJ
_RS06180
-3.7
-3.5
tryptophan--tRNA ligase
compare
MMJJ
_RS07380
-3.6
-10.3
sulfide-dependent adenosine diphosphate thiazole synthase
compare
MMJJ
_RS02275
-3.5
-5.6
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS08250
-3.5
-8.3
hydrogenase maturation peptidase HycI
compare
MMJJ
_RS07670
-3.5
-19.7
Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain
compare
MMJJ
_RS03055
-3.5
-4.4
hypothetical protein
compare
MMJJ
_RS01600
-3.4
-3.7
radical SAM protein
compare
MMJJ
_RS05535
-3.4
-15.5
hypothetical protein
compare
MMJJ
_RS08320
-3.4
-2.8
CDP-diacylglycerol--serine O-phosphatidyltransferase
compare
MMJJ
_RS06625
-3.4
-2.7
pyruvate synthase subunit PorB
compare
MMJJ
_RS00370
-3.4
-2.5
asparagine synthase (glutamine-hydrolyzing)
compare
MMJJ
_RS01415
-3.4
-3.5
beta-CASP ribonuclease aCPSF1
compare
MMJJ
_RS05935
-3.3
-3.0
Era-like GTP-binding protein
compare
MMJJ
_RS06510
-3.3
-3.5
LL-diaminopimelate aminotransferase
compare
MMJJ
_RS04155
-3.3
-9.4
hypothetical protein
compare
MMJJ
_RS03815
-3.3
-2.7
nascent polypeptide-associated complex protein
compare
MMJJ
_RS06040
-3.3
-6.0
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS07705
-3.2
-4.6
GTP-binding protein EngB
compare
MMJJ
_RS03005
-3.2
-4.6
Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit
compare
MMJJ
_RS05445
-3.2
-3.0
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
MMJJ
_RS06910
-3.2
-3.6
energy-converting NiFe hydrogenase A subunit EhaA
compare
MMJJ
_RS08005
-3.1
-18.5
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMJJ
_RS07720
-3.1
-2.9
UPF0058 family protein
compare
MMJJ
_RS00270
-3.0
-4.0
adenosylcobinamide-GDP ribazoletransferase
compare
MMJJ
_RS04995
-3.0
-8.2
Tfx family DNA-binding protein
compare
MMJJ
_RS04800
-3.0
-6.0
2-phospho-L-lactate guanylyltransferase
compare
MMJJ
_RS04685
-3.0
-11.0
carbamoyltransferase HypF
compare
MMJJ
_RS03895
-3.0
-3.9
hydrogenase expression/formation protein HypE
compare
MMJJ
_RS03820
-3.0
-5.1
hydrogenase formation protein HypD
compare
MMJJ
_RS07655
-3.0
-13.8
hypothetical protein
compare
MMJJ
_RS00210
-2.9
-3.1
DUF530 family protein
compare
MMJJ
_RS07350
-2.9
-4.4
4Fe-4S binding protein
compare
MMJJ
_RS01565
-2.9
-8.1
TIGR00267 family protein
compare
MMJJ
_RS02935
-2.9
-3.8
DNA-directed RNA polymerase subunit E''
compare
MMJJ
_RS03200
-2.9
-2.6
uroporphyrinogen-III synthase
compare
MMJJ
_RS05260
-2.9
-8.5
ATP-grasp domain-containing protein
compare
MMJJ
_RS08055
-2.9
-7.8
methanogenesis marker 14 protein
compare
MMJJ
_RS03670
-2.8
-4.2
precorrin-2 C(20)-methyltransferase
compare
MMJJ
_RS06725
-2.8
-13.0
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMJJ
_RS08340
-2.8
-6.3
archaeoflavoprotein AfpA
compare
MMJJ
_RS03865
-2.8
-2.1
phosphoribosyl-AMP cyclohydrolase
compare
MMJJ
_RS08000
-2.8
-10.5
HesA/MoeB/ThiF family protein
compare
MMJJ
_RS03660
-2.8
-5.0
DUF447 family protein
compare
MMJJ
_RS06695
-2.7
-3.5
amidohydrolase
compare
MMJJ
_RS08020
-2.7
-7.8
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS07360
-2.7
-2.0
TIGR00269 family protein
compare
MMJJ
_RS00520
-2.7
-7.9
PDGLE domain-containing protein
compare
MMJJ
_RS06255
-2.7
-7.8
tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3
compare
MMJJ
_RS02045
-2.7
-3.6
molybdenum cofactor guanylyltransferase
compare
MMJJ
_RS07660
-2.7
-9.1
carbonic anhydrase
compare
MMJJ
_RS06840
-2.7
-5.0
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS05190
-2.7
-9.2
gamma carbonic anhydrase family protein
compare
MMJJ
_RS05330
-2.7
-3.3
DNA polymerase II large subunit
compare
MMJJ
_RS06865
-2.7
-3.7
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS03840
-2.6
-5.4
DHH family phosphoesterase
compare
MMJJ
_RS02090
-2.6
-6.3
tyramine--L-glutamate ligase
compare
MMJJ
_RS05575
-2.6
-5.9
2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase
compare
MMJJ
_RS04970
-2.6
-2.4
DUF655 domain-containing protein
compare
MMJJ
_RS04975
-2.6
-2.3
glycosyltransferase family 4 protein
compare
MMJJ
_RS06730
-2.6
-7.4
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS06490
-2.6
-3.2
methanogenesis marker 2 protein
compare
MMJJ
_RS04790
-2.6
-4.9
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMJJ
_RS03060
-2.6
-3.7
methanogenesis marker 7 protein
compare
MMJJ
_RS01690
-2.6
-4.7
methanogenesis marker 12 protein
compare
MMJJ
_RS03785
-2.6
-3.6
hypothetical protein
compare
MMJJ
_RS06915
-2.5
-13.0
helix-turn-helix domain-containing protein
compare
MMJJ
_RS06785
-2.5
-8.1
RNA ligase partner protein
compare
MMJJ
_RS07410
-2.5
-4.5
methanogenesis marker protein Mmp4/MtxX
compare
MMJJ
_RS08660
-2.5
-3.8
acetylornithine transaminase
compare
MMJJ
_RS03295
-2.5
-15.5
PHP domain-containing protein
compare
MMJJ
_RS04980
-2.5
-5.0
bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase
compare
MMJJ
_RS00070
-2.5
-4.4
CooT family nickel-binding protein
compare
MMJJ
_RS04050
-2.4
-2.2
dihydroneopterin aldolase family protein
compare
MMJJ
_RS03965
-2.4
-2.2
DNA-directed RNA polymerase subunit L
compare
MMJJ
_RS08080
-2.4
-8.8
TIGR00300 family protein
compare
MMJJ
_RS05225
-2.4
-1.9
Gar1/Naf1 family protein
compare
MMJJ
_RS08625
-2.4
-6.9
magnesium/cobalt transporter CorA
compare
MMJJ
_RS00570
-2.4
-2.3
ribonuclease P
compare
MMJJ
_RS00050
-2.4
-12.2
AAA family ATPase
compare
MMJJ
_RS00065
-2.4
-12.4
4Fe-4S dicluster domain-containing protein
compare
MMJJ
_RS07640
-2.4
-18.1
cache domain-containing protein
compare
MMJJ
_RS04485
-2.4
-10.0
riboflavin synthase
compare
MMJJ
_RS00035
-2.4
-16.5
CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
compare
MMJJ
_RS07785
-2.3
-2.9
fumarate reductase subunit A
compare
MMJJ
_RS03830
-2.3
-9.6
CBS domain-containing protein
compare
MMJJ
_RS03875
-2.3
-5.8
CBS domain-containing protein
compare
MMJJ
_RS06705
-2.3
-6.2
bifunctional NADP phosphatase/NAD kinase
compare
MMJJ
_RS06155
-2.3
-5.5
phosphatidylglycerophosphatase A
compare
MMJJ
_RS00045
-2.3
-12.9
CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
compare
MMJJ
_RS05810
-2.3
-6.7
precorrin-4 C(11)-methyltransferase
compare
MMJJ
_RS03125
-2.3
-4.5
GMC oxidoreductase
compare
MMJJ
_RS00355
-2.3
-3.0
ribonuclease P protein component 4
compare
MMJJ
_RS00360
-2.3
-3.6
adenosylhomocysteinase
compare
MMJJ
_RS04655
-2.3
-6.6
FAD-dependent oxidoreductase
compare
MMJJ
_RS03150
-2.3
-5.6
2-phospho-L-lactate transferase
compare
MMJJ
_RS03630
-2.3
-11.5
AMP phosphorylase
compare
MMJJ
_RS07245
-2.3
-5.3
amidohydrolase family protein
compare
MMJJ
_RS05655
-2.2
-6.2
HisA/HisF family protein
compare
MMJJ
_RS06750
-2.2
-2.1
homoaconitase large subunit
compare
MMJJ
_RS03800
-2.2
-9.4
aldolase
compare
MMJJ
_RS00055
-2.2
-10.4
CO dehydrogenase/acetyl-CoA synthase subunit delta
compare
MMJJ
_RS06050
-2.2
-12.3
molybdopterin molybdotransferase MoeA
compare
MMJJ
_RS07000
-2.2
-2.0
TrkH family potassium uptake protein
compare
MMJJ
_RS04615
-2.2
-3.5
methanogenesis marker 3 protein
compare
MMJJ
_RS06375
-2.2
-4.0
UbiX family flavin prenyltransferase
compare
MMJJ
_RS04730
-2.2
-3.1
tyrosine decarboxylase MfnA
compare
MMJJ
_RS06835
-2.2
-12.0
4Fe-4S binding protein
compare
MMJJ
_RS05490
-2.2
-3.3
imidazole glycerol phosphate synthase subunit HisF
compare
MMJJ
_RS00060
-2.2
-14.3
acetyl-CoA decarbonylase/synthase complex subunit gamma
compare
MMJJ
_RS00600
-2.2
-2.8
hydroxymethylbilane synthase
compare
MMJJ
_RS07650
-2.2
-16.1
formate/nitrite transporter family protein
compare
MMJJ
_RS03620
-2.1
-5.5
DUF2097 domain-containing protein
compare
MMJJ
_RS06855
-2.1
-2.1
DUF2104 domain-containing protein
compare
MMJJ
_RS07995
-2.1
-6.7
molybdenum cofactor biosynthesis protein MoaE
compare
MMJJ
_RS04520
-2.1
-5.7
coenzyme F430 synthase
compare
MMJJ
_RS00080
-2.1
-11.6
DUF166 domain-containing protein
compare
MMJJ
_RS08840
-2.1
-5.6
calcium/sodium antiporter
compare
MMJJ
_RS05375
-2.1
-15.4
radical SAM protein
compare
MMJJ
_RS04675
-2.1
-5.4
thiamine pyrophosphate-binding protein
compare
MMJJ
_RS06225
-2.1
-2.4
adenosylmethionine decarboxylase
compare
MMJJ
_RS07425
-2.1
-10.6
MBL fold metallo-hydrolase
compare
MMJJ
_RS01345
-2.1
-3.7
(5-formylfuran-3-yl)methyl phosphate synthase
compare
MMJJ
_RS06215
-2.1
-5.0
agmatinase
compare
MMJJ
_RS06220
-2.1
-5.8
polyamine aminopropyltransferase
compare
MMJJ
_RS03190
-2.1
-3.1
phosphopyruvate hydratase
compare
MMJJ
_RS03110
-2.1
-3.0
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase
compare
MMJJ
_RS00075
-2.0
-10.4
AAA family ATPase
compare
MMJJ
_RS07635
-2.0
-12.1
response regulator transcription factor
compare
MMJJ
_RS00040
-2.0
-7.7
CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
compare
MMJJ
_RS05995
-2.0
-2.6
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS00530
-2.0
-10.9
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS01880
-2.0
-3.1
RlmE family RNA methyltransferase
compare
MMJJ
_RS05360
-2.0
-6.3
nickel-responsive transcriptional regulator NikR
compare
MMJJ
_RS00580
-2.0
-1.6
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG
compare
MMJJ
_RS07725
-2.0
-6.0
DNA primase DnaG
compare
MMJJ
_RS06000
-2.0
-4.9
cation:proton antiporter subunit C
compare
MMJJ
_RS09175
-2.0
-1.6
anthranilate synthase component I
compare
MMJJ
_RS07945
-2.0
-2.9
4Fe-4S binding protein
compare
MMJJ
_RS01865
-2.0
-4.3
peptidyl-tRNA hydrolase Pth2
compare
MMJJ
_RS05930
-2.0
-2.0
cell division protein SepF
compare
MMJJ
_RS00450
-2.0
-2.2
DUF126 domain-containing protein
compare
MMJJ
_RS04620
-2.0
-3.1
homocitrate synthase family protein
compare
MMJJ
_RS06485
-2.0
-3.5
phosphoglycerate kinase
compare
MMJJ
_RS04475
-1.9
-3.4
3,4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMJJ
_RS05590
-1.9
-2.2
homoserine dehydrogenase
compare
MMJJ
_RS05155
-1.9
-6.1
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH
compare
MMJJ
_RS00515
-1.9
-9.0
cobalt transporter CbiM
compare
MMJJ
_RS00475
-1.9
-2.6
bifunctional ornithine acetyltransferase/N-acetylglutamate synthase
compare
MMJJ
_RS02055
-1.9
-10.2
GTP 3',8-cyclase MoaA
compare
MMJJ
_RS04010
-1.9
-7.6
archaeal proteasome endopeptidase complex subunit alpha
compare
MMJJ
_RS09375
-1.9
-1.7
hypothetical protein
compare
MMJJ
_RS00560
-1.9
-3.9
homoisocitrate dehydrogenase
compare
MMJJ
_RS00215
-1.9
-1.9
CCA tRNA nucleotidyltransferase
compare
MMJJ
_RS08855
-1.9
-4.5
cyclic pyranopterin monophosphate synthase MoaC
compare
MMJJ
_RS04670
-1.9
-5.4
DUF2117 domain-containing protein
compare
MMJJ
_RS08330
-1.9
-2.4
SufD family Fe-S cluster assembly protein
compare
MMJJ
_RS03615
-1.9
-2.1
cobalt-precorrin-8 methylmutase
compare
MMJJ
_RS07355
-1.8
-4.9
MoaD/ThiS family protein
compare
MMJJ
_RS04650
-1.8
-5.9
nitrogenase iron protein
compare
MMJJ
_RS05950
-1.8
-2.6
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
compare
MMJJ
_RS00125
-1.8
-2.3
KEOPS complex subunit Cgi121
compare
MMJJ
_RS06185
-1.8
-4.9
cobalamin biosynthesis protein
compare
MMJJ
_RS06015
-1.8
-10.2
Na(+)/H(+) antiporter subunit B
compare
MMJJ
_RS01355
-1.8
-3.1
UDP-N-acetyl-D-mannosamine dehydrogenase
compare
MMJJ
_RS01360
-1.8
-2.4
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMJJ
_RS07345
-1.8
-5.2
homocysteine biosynthesis protein
compare
MMJJ
_RS08155
-1.8
-3.5
cobalt-precorrin-5B (C(1))-methyltransferase CbiD
compare
MMJJ
_RS08620
-1.8
-3.6
DUF373 family protein
compare
MMJJ
_RS04985
-1.8
-3.4
glutamyl-tRNA reductase
compare
MMJJ
_RS08535
-1.8
-3.4
NOL1/NOP2/sun family putative RNA methylase
compare
MMJJ
_RS05610
-1.8
-4.1
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMJJ
_RS02035
-1.8
-6.6
4-hydroxy-tetrahydrodipicolinate synthase
compare
MMJJ
_RS06250
-1.7
-2.8
nicotinamide-nucleotide adenylyltransferase
compare
MMJJ
_RS07155
-1.7
-7.1
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMJJ
_RS06760
-1.7
-3.8
Ni-sirohydrochlorin a,c-diamide synthase
compare
MMJJ
_RS06175
-1.7
-2.2
DUF1743 domain-containing protein
compare
MMJJ
_RS04875
-1.7
-1.6
tRNA-Lys
compare
MMJJ
_RS05065
-1.7
-3.2
(4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase
compare
MMJJ
_RS04595
-1.7
-4.5
hypothetical protein
compare
MMJJ
_RS00265
-1.7
-5.6
TIGR02253 family HAD-type hydrolase
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments