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Experiment set3IT045 for
Methanococcus maripaludis JJ
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formate McAA thiamine dropout
200 most detrimental genes:
gene
name
fitness
t score
description
MMJJ
_RS04415
+2.9
11.4
hypothetical protein
compare
MMJJ
_RS08830
+1.3
4.4
hypothetical protein
compare
MMJJ
_RS03725
+1.3
4.3
sulfurtransferase TusA family protein
compare
MMJJ
_RS04005
+1.1
8.6
acetate--CoA ligase family protein
compare
MMJJ
_RS06675
+0.8
6.0
TIGR01212 family radical SAM protein
compare
MMJJ
_RS05685
+0.8
5.0
class III signal peptide-containing protein
compare
MMJJ
_RS08130
+0.8
0.7
translation initiation factor IF-2 subunit gamma
compare
MMJJ
_RS06540
+0.8
2.0
DUF2120 domain-containing protein
compare
MMJJ
_RS06505
+0.8
2.6
prephenate dehydratase
compare
MMJJ
_RS07240
+0.7
5.8
MBL fold metallo-hydrolase
compare
MMJJ
_RS06680
+0.7
3.2
DUF366 family protein
compare
MMJJ
_RS01855
+0.6
4.4
MBL fold metallo-hydrolase
compare
MMJJ
_RS07185
+0.6
1.8
DUF371 domain-containing protein
compare
MMJJ
_RS06500
+0.6
3.9
class I SAM-dependent methyltransferase
compare
MMJJ
_RS07260
+0.6
3.7
PspC domain-containing protein
compare
MMJJ
_RS07220
+0.6
4.2
coenzyme F420 hydrogenase subunit beta
compare
MMJJ
_RS07005
+0.6
2.4
transcription factor S
compare
MMJJ
_RS07750
+0.6
1.8
class III signal peptide-containing protein
compare
MMJJ
_RS08410
+0.5
1.2
CBS domain-containing protein
compare
MMJJ
_RS04955
+0.5
2.9
tRNA pseudouridine(54/55) synthase Pus10
compare
MMJJ
_RS07010
+0.5
2.4
preprotein translocase subunit Sec61beta
compare
MMJJ
_RS07280
+0.5
3.1
phosphomannomutase/phosphoglucomutase
compare
MMJJ
_RS07450
+0.5
3.2
hypothetical protein
compare
MMJJ
_RS03375
+0.5
2.9
hypothetical protein
compare
MMJJ
_RS06190
+0.5
3.7
7-cyano-7-deazaguanine synthase
compare
MMJJ
_RS06210
+0.5
2.3
hypothetical protein
compare
MMJJ
_RS07025
+0.5
2.3
tRNA (cytidine(56)-2'-O)-methyltransferase
compare
MMJJ
_RS04375
+0.5
1.9
hypothetical protein
compare
MMJJ
_RS09120
+0.5
0.7
aspartate kinase
compare
MMJJ
_RS06460
+0.5
2.7
cytochrome c
compare
MMJJ
_RS06440
+0.5
3.4
DUF4870 domain-containing protein
compare
MMJJ
_RS06515
+0.5
3.4
ribonuclease III
compare
MMJJ
_RS07680
+0.5
3.2
glucose-6-phosphate isomerase
compare
MMJJ
_RS06385
+0.5
2.6
hypothetical protein
compare
MMJJ
_RS06950
+0.5
3.8
4-demethylwyosine synthase TYW1
compare
MMJJ
_RS07225
+0.5
3.6
coenzyme F420 hydrogenase subunit gamma
compare
MMJJ
_RS06090
+0.5
2.7
hypothetical protein
compare
MMJJ
_RS07985
+0.5
2.7
hypothetical protein
compare
MMJJ
_RS07890
+0.5
3.0
pyrimidine dimer DNA glycosylase/endonuclease V
compare
MMJJ
_RS09360
+0.5
3.0
hypothetical protein
compare
MMJJ
_RS06280
+0.5
3.2
hypothetical protein
compare
MMJJ
_RS07495
+0.5
2.7
4Fe-4S binding protein
compare
MMJJ
_RS06535
+0.5
3.5
UPF0104 family protein
compare
MMJJ
_RS07235
+0.5
3.5
coenzyme F420 hydrogenase subunit alpha
compare
MMJJ
_RS06745
+0.5
2.0
energy-coupling factor ABC transporter permease
compare
MMJJ
_RS06735
+0.5
3.0
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS06800
+0.5
2.2
prefoldin subunit alpha
compare
MMJJ
_RS09365
+0.4
1.5
hypothetical protein
compare
MMJJ
_RS03835
+0.4
1.5
DUF504 domain-containing protein
compare
MMJJ
_RS07205
+0.4
1.9
MTH895/ArsE family thioredoxin-like protein
compare
MMJJ
_RS05975
+0.4
2.6
sulfurtransferase TusA family protein
compare
MMJJ
_RS07795
+0.4
2.2
cupin domain-containing protein
compare
MMJJ
_RS01745
+0.4
2.3
metal-dependent transcriptional regulator
compare
MMJJ
_RS06520
+0.4
2.8
TldD/PmbA family protein
compare
MMJJ
_RS09065
+0.4
2.2
hypothetical protein
compare
MMJJ
_RS04105
+0.4
3.2
prepilin peptidase
compare
MMJJ
_RS06770
+0.4
3.2
hypothetical protein
compare
MMJJ
_RS07480
+0.4
3.0
FAD-dependent oxidoreductase
compare
MMJJ
_RS06085
+0.4
1.5
proteasome assembly chaperone family protein
compare
MMJJ
_RS01825
+0.4
2.1
DNA repair and recombination protein RadB
compare
MMJJ
_RS06665
+0.4
1.3
DUF3236 domain-containing protein
compare
MMJJ
_RS06810
+0.4
3.0
L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha
compare
MMJJ
_RS06790
+0.4
3.0
nucleotidyltransferase family protein
compare
MMJJ
_RS07765
+0.4
1.5
DMT family protein
compare
MMJJ
_RS06470
+0.4
2.8
tripartite tricarboxylate transporter permease
compare
MMJJ
_RS06205
+0.4
2.4
EamA family transporter
compare
MMJJ
_RS07920
+0.4
2.5
6-carboxytetrahydropterin synthase QueD
compare
MMJJ
_RS06685
+0.4
3.1
S-layer protein
compare
MMJJ
_RS00890
+0.4
2.3
coenzyme F420 hydrogenase subunit gamma
compare
MMJJ
_RS07800
+0.4
2.8
AMP-binding protein
compare
MMJJ
_RS08225
+0.4
1.2
peptidylprolyl isomerase
compare
MMJJ
_RS07270
+0.4
2.3
ribonuclease HII
compare
MMJJ
_RS04850
+0.4
1.7
energy-coupling factor transporter transmembrane protein EcfT
compare
MMJJ
_RS04215
+0.4
2.7
DMT family transporter
compare
MMJJ
_RS05510
+0.4
2.2
archaellum operon transcriptional activator EarA family protein
compare
MMJJ
_RS04545
+0.4
1.2
PadR family transcriptional regulator
compare
MMJJ
_RS07230
+0.4
1.9
coenzyme F420-reducing hydrogenase, FrhD protein
compare
MMJJ
_RS08515
+0.4
1.3
secondary thiamine-phosphate synthase enzyme YjbQ
compare
MMJJ
_RS05040
+0.3
2.3
7-carboxy-7-deazaguanine synthase QueE
compare
MMJJ
_RS04135
+0.3
1.3
7-cyano-7-deazaguanine synthase QueC
compare
MMJJ
_RS09230
+0.3
1.1
hypothetical protein
compare
MMJJ
_RS05530
+0.3
0.7
roadblock/LC7 domain-containing protein
compare
MMJJ
_RS05980
+0.3
2.1
DUF5400 domain-containing protein
compare
MMJJ
_RS07215
+0.3
2.6
TIGR00341 family protein
compare
MMJJ
_RS08375
+0.3
2.2
ferritin
compare
MMJJ
_RS00150
+0.3
1.6
DUF2180 family protein
compare
MMJJ
_RS08285
+0.3
2.1
class I SAM-dependent methyltransferase
compare
MMJJ
_RS06120
+0.3
2.2
DUF4013 domain-containing protein
compare
MMJJ
_RS08100
+0.3
1.7
hypothetical protein
compare
MMJJ
_RS06075
+0.3
2.0
DNA-binding protein Alba
compare
MMJJ
_RS06640
+0.3
1.9
YfcE family phosphodiesterase
compare
MMJJ
_RS07445
+0.3
2.0
RlmF-related methyltransferase
compare
MMJJ
_RS04635
+0.3
1.6
DUF367 family protein
compare
MMJJ
_RS05200
+0.3
2.3
TIGR04013 family B12-binding domain/radical SAM domain-containing protein
compare
MMJJ
_RS06275
+0.3
1.1
hypothetical protein
compare
MMJJ
_RS07210
+0.3
2.2
AmmeMemoRadiSam system protein B
compare
MMJJ
_RS03575
+0.3
1.3
NUDIX hydrolase
compare
MMJJ
_RS06285
+0.3
1.7
YchF/TatD family DNA exonuclease
compare
MMJJ
_RS05580
+0.3
1.6
methanogenesis marker 9 domain-containing protein
compare
MMJJ
_RS06455
+0.3
2.1
YeeE/YedE family protein
compare
MMJJ
_RS02115
+0.3
2.1
class I SAM-dependent methyltransferase family protein
compare
MMJJ
_RS00305
+0.3
2.0
chemotaxis protein CheC
compare
MMJJ
_RS09015
+0.3
1.7
SPFH domain-containing protein
compare
MMJJ
_RS01530
+0.3
0.7
YwbE family protein
compare
MMJJ
_RS00320
+0.3
1.5
chemotaxis protein CheD
compare
MMJJ
_RS07385
+0.3
1.9
ribosomal protein S18-alanine N-acetyltransferase
compare
MMJJ
_RS06585
+0.3
1.6
alanine racemase
compare
MMJJ
_RS00155
+0.3
2.1
DUF2193 domain-containing protein
compare
MMJJ
_RS00145
+0.3
2.0
aquaporin family protein
compare
MMJJ
_RS08160
+0.3
1.2
tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO
compare
MMJJ
_RS06430
+0.3
1.5
haloacid dehalogenase
compare
MMJJ
_RS02270
+0.3
1.0
HEPN domain-containing protein
compare
MMJJ
_RS08935
+0.3
0.4
TIGR00288 family NYN domain-containing protein
compare
MMJJ
_RS07500
+0.3
2.2
hypothetical protein
compare
MMJJ
_RS03515
+0.3
1.5
GPR1/FUN34/YaaH family transporter
compare
MMJJ
_RS04345
+0.3
1.0
DUF2080 family transposase-associated protein
compare
MMJJ
_RS01270
+0.3
1.6
4Fe-4S binding protein
compare
MMJJ
_RS08520
+0.3
0.6
peptidylprolyl isomerase
compare
MMJJ
_RS06960
+0.3
2.2
CAP domain-containing protein
compare
MMJJ
_RS01100
+0.3
0.6
helix-turn-helix domain-containing protein
compare
MMJJ
_RS08370
+0.3
1.1
hypothetical protein
compare
MMJJ
_RS06740
+0.3
1.2
energy-coupling factor ABC transporter substrate-binding protein
compare
MMJJ
_RS08305
+0.3
1.1
peroxiredoxin
compare
MMJJ
_RS06445
+0.3
2.2
hypothetical protein
compare
MMJJ
_RS07860
+0.3
1.3
hypothetical protein
compare
MMJJ
_RS06235
+0.3
1.9
IGHMBP2 family helicase
compare
MMJJ
_RS03730
+0.3
1.4
SWIM zinc finger family protein
compare
MMJJ
_RS02180
+0.3
1.2
DHH family phosphoesterase
compare
MMJJ
_RS02230
+0.3
2.0
hypothetical protein
compare
MMJJ
_RS06100
+0.3
1.4
rubrerythrin
compare
MMJJ
_RS04390
+0.3
1.8
rhomboid family intramembrane serine protease
compare
MMJJ
_RS08685
+0.3
1.7
phosphate ABC transporter permease subunit PstC
compare
MMJJ
_RS08485
+0.3
1.0
Lrp/AsnC family transcriptional regulator
compare
MMJJ
_RS08580
+0.2
1.3
YkgJ family cysteine cluster protein
compare
MMJJ
_RS05390
+0.2
1.6
tRNA pseudouridine(13) synthase TruD
compare
MMJJ
_RS03595
+0.2
0.9
hypothetical protein
compare
MMJJ
_RS05700
+0.2
1.6
metallophosphoesterase
compare
MMJJ
_RS04410
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS05505
+0.2
2.3
hypothetical protein
compare
MMJJ
_RS06765
+0.2
1.9
hypothetical protein
compare
MMJJ
_RS00630
+0.2
1.3
betaine/proline/choline family ABC transporter ATP-binding protein
compare
MMJJ
_RS08930
+0.2
1.5
5'/3'-nucleotidase SurE
compare
MMJJ
_RS03450
+0.2
1.1
hypothetical protein
compare
MMJJ
_RS01970
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS08350
+0.2
2.0
heavy metal translocating P-type ATPase
compare
MMJJ
_RS02895
+0.2
1.5
ATP-binding protein
compare
MMJJ
_RS08310
+0.2
1.2
ZIP family metal transporter
compare
MMJJ
_RS03290
+0.2
1.8
amidohydrolase
compare
MMJJ
_RS07255
+0.2
1.9
hypothetical protein
compare
MMJJ
_RS06135
+0.2
1.6
50S ribosomal protein L11 methyltransferase
compare
MMJJ
_RS04240
+0.2
1.8
molybdate ABC transporter substrate-binding protein
compare
MMJJ
_RS02160
+0.2
1.5
amino acid ABC transporter permease
compare
MMJJ
_RS01300
+0.2
1.4
MarR family transcriptional regulator
compare
MMJJ
_RS04815
+0.2
0.9
TIM barrel protein
compare
MMJJ
_RS09020
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS01035
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS06710
+0.2
1.6
TldD/PmbA family protein
compare
MMJJ
_RS02330
+0.2
1.8
ABC transporter ATP-binding protein
compare
MMJJ
_RS07815
+0.2
1.5
2-oxoacid:acceptor oxidoreductase family protein
compare
MMJJ
_RS01785
+0.2
0.3
50S ribosomal protein L14e
compare
MMJJ
_RS05585
+0.2
1.4
hypothetical protein
compare
MMJJ
_RS06495
+0.2
0.6
hypothetical protein
compare
MMJJ
_RS01395
+0.2
0.8
DUF1894 domain-containing protein
compare
MMJJ
_RS04500
+0.2
1.2
hypothetical protein
compare
MMJJ
_RS03040
+0.2
1.2
lactate utilization protein
compare
MMJJ
_RS06290
+0.2
1.3
DUF749 domain-containing protein
compare
MMJJ
_RS07835
+0.2
1.2
UPF0489 family protein
compare
MMJJ
_RS07365
+0.2
1.4
CatB-related O-acetyltransferase
compare
MMJJ
_RS07760
+0.2
1.1
GNAT family N-acetyltransferase
compare
MMJJ
_RS06590
+0.2
1.5
sodium:alanine symporter family protein
compare
MMJJ
_RS03905
+0.2
1.2
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS04195
+0.2
1.0
XTP/dITP diphosphatase
compare
MMJJ
_RS03025
+0.2
1.6
Ig-like domain-containing protein
compare
MMJJ
_RS09005
+0.2
1.6
N-6 DNA methylase
compare
MMJJ
_RS03395
+0.2
0.5
hypothetical protein
compare
MMJJ
_RS05355
+0.2
1.3
DUF2121 domain-containing protein
compare
MMJJ
_RS05750
+0.2
1.4
flagellar accessory protein FlaH
compare
MMJJ
_RS07595
+0.2
0.9
hypothetical protein
compare
MMJJ
_RS03380
+0.2
0.9
hypothetical protein
compare
MMJJ
_RS08275
+0.2
1.7
iron ABC transporter substrate-binding protein
compare
MMJJ
_RS05500
+0.2
1.6
hypothetical protein
compare
MMJJ
_RS00740
+0.2
0.9
hypothetical protein
compare
MMJJ
_RS08670
+0.2
1.3
phosphate signaling complex protein PhoU
compare
MMJJ
_RS07820
+0.2
1.3
bifunctional hexulose-6-phosphate synthase/ribonuclease regulator
compare
MMJJ
_RS00395
+0.2
1.2
DUF473 domain-containing protein
compare
MMJJ
_RS08255
+0.2
1.2
GNAT family N-acetyltransferase
compare
MMJJ
_RS07175
+0.2
1.4
DEAD/DEAH box helicase
compare
MMJJ
_RS07745
+0.2
1.3
DUF5814 domain-containing protein
compare
MMJJ
_RS04950
+0.2
1.4
TIGR00375 family protein
compare
MMJJ
_RS06450
+0.2
1.2
DUF3343 domain-containing protein
compare
MMJJ
_RS04070
+0.2
1.5
DUF2341 domain-containing protein
compare
MMJJ
_RS05925
+0.2
1.2
DUF2099 family protein
compare
MMJJ
_RS02335
+0.2
1.4
ABC transporter substrate-binding protein
compare
MMJJ
_RS07935
+0.2
0.2
protein fwdD
compare
MMJJ
_RS08395
+0.2
1.3
CoB--CoM heterodisulfide reductase subunit B
compare
MMJJ
_RS06055
+0.2
1.1
S-methyl-5-thioribose-1-phosphate isomerase
compare
MMJJ
_RS02340
+0.2
0.8
SAM-dependent methyltransferase
compare
MMJJ
_RS02295
+0.2
1.4
hypothetical protein
compare
MMJJ
_RS05895
+0.2
1.4
ABC transporter permease
compare
MMJJ
_RS04430
+0.2
1.2
purine NTPase
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments