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Experiment set3IT044 for
Methanococcus maripaludis JJ
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formate McAA thiamine dropout
200 most important genes:
gene
name
fitness
t score
description
MMJJ
_RS00235
-6.6
-23.9
hypothetical protein
compare
MMJJ
_RS03895
-5.6
-5.0
hydrogenase expression/formation protein HypE
compare
MMJJ
_RS06625
-5.4
-2.7
pyruvate synthase subunit PorB
compare
MMJJ
_RS05445
-5.2
-2.6
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
MMJJ
_RS00210
-5.0
-2.8
DUF530 family protein
compare
MMJJ
_RS06750
-5.0
-2.8
homoaconitase large subunit
compare
MMJJ
_RS05450
-4.9
-18.3
TIGR03576 family pyridoxal phosphate-dependent enzyme
compare
MMJJ
_RS06240
-4.8
-4.1
dihydropteroate synthase-like protein
compare
MMJJ
_RS03580
-4.8
-4.6
TIGR00303 family protein
compare
MMJJ
_RS06910
-4.8
-2.9
energy-converting NiFe hydrogenase A subunit EhaA
compare
MMJJ
_RS00570
-4.8
-2.7
ribonuclease P
compare
MMJJ
_RS07380
-4.7
-12.5
sulfide-dependent adenosine diphosphate thiazole synthase
compare
MMJJ
_RS06860
-4.7
-5.3
hypothetical protein
compare
MMJJ
_RS06490
-4.7
-3.2
methanogenesis marker 2 protein
compare
MMJJ
_RS04200
-4.5
-8.6
triphosphoribosyl-dephospho-CoA synthase
compare
MMJJ
_RS05650
-4.4
-4.2
formylmethanofuran dehydrogenase subunit B
compare
MMJJ
_RS06250
-4.3
-2.9
nicotinamide-nucleotide adenylyltransferase
compare
MMJJ
_RS07705
-4.2
-4.4
GTP-binding protein EngB
compare
MMJJ
_RS06510
-4.2
-3.6
LL-diaminopimelate aminotransferase
compare
MMJJ
_RS06695
-4.2
-4.5
amidohydrolase
compare
MMJJ
_RS01935
-4.2
-5.6
O-phosphoseryl-tRNA(Sec) selenium transferase
compare
MMJJ
_RS00370
-4.1
-2.1
asparagine synthase (glutamine-hydrolyzing)
compare
MMJJ
_RS09375
-4.1
-2.5
hypothetical protein
compare
MMJJ
_RS07785
-4.1
-3.8
fumarate reductase subunit A
compare
MMJJ
_RS05620
-4.0
-4.8
CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein
compare
MMJJ
_RS01750
-4.0
-3.5
ferrous iron transport protein A
compare
MMJJ
_RS08330
-4.0
-4.7
SufD family Fe-S cluster assembly protein
compare
MMJJ
_RS02090
-4.0
-6.9
tyramine--L-glutamate ligase
compare
MMJJ
_RS07410
-4.0
-5.9
methanogenesis marker protein Mmp4/MtxX
compare
MMJJ
_RS01600
-3.9
-4.3
radical SAM protein
compare
MMJJ
_RS07665
-3.8
-23.9
formate dehydrogenase subunit alpha
compare
MMJJ
_RS03270
-3.8
-3.1
ribosome biogenesis/translation initiation ATPase RLI
compare
MMJJ
_RS05610
-3.8
-6.2
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMJJ
_RS05575
-3.8
-5.5
2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase
compare
MMJJ
_RS03785
-3.8
-3.6
hypothetical protein
compare
MMJJ
_RS07470
-3.8
-2.5
50S ribosome-binding GTPase
compare
MMJJ
_RS03875
-3.7
-4.6
CBS domain-containing protein
compare
MMJJ
_RS04975
-3.7
-2.7
glycosyltransferase family 4 protein
compare
MMJJ
_RS05535
-3.7
-14.8
hypothetical protein
compare
MMJJ
_RS07670
-3.7
-20.5
Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain
compare
MMJJ
_RS03840
-3.6
-5.5
DHH family phosphoesterase
compare
MMJJ
_RS08020
-3.6
-9.3
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS00580
-3.6
-2.4
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG
compare
MMJJ
_RS05935
-3.6
-3.0
Era-like GTP-binding protein
compare
MMJJ
_RS06390
-3.6
-2.4
NADPH-dependent F420 reductase
compare
MMJJ
_RS05330
-3.6
-3.1
DNA polymerase II large subunit
compare
MMJJ
_RS01415
-3.6
-3.3
beta-CASP ribonuclease aCPSF1
compare
MMJJ
_RS06040
-3.5
-5.1
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS04485
-3.5
-13.2
riboflavin synthase
compare
MMJJ
_RS03660
-3.5
-5.0
DUF447 family protein
compare
MMJJ
_RS08250
-3.5
-8.4
hydrogenase maturation peptidase HycI
compare
MMJJ
_RS03670
-3.5
-5.8
precorrin-2 C(20)-methyltransferase
compare
MMJJ
_RS03125
-3.5
-5.5
GMC oxidoreductase
compare
MMJJ
_RS05415
-3.4
-1.9
hypothetical protein
compare
MMJJ
_RS06155
-3.4
-6.2
phosphatidylglycerophosphatase A
compare
MMJJ
_RS02920
-3.4
-3.0
30S ribosomal protein S27ae
compare
MMJJ
_RS03110
-3.4
-5.1
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase
compare
MMJJ
_RS08625
-3.4
-9.1
magnesium/cobalt transporter CorA
compare
MMJJ
_RS03820
-3.3
-5.2
hydrogenase formation protein HypD
compare
MMJJ
_RS02040
-3.3
-2.2
Asp-tRNA(Asn) amidotransferase subunit GatC
compare
MMJJ
_RS06705
-3.3
-6.5
bifunctional NADP phosphatase/NAD kinase
compare
MMJJ
_RS02045
-3.2
-4.0
molybdenum cofactor guanylyltransferase
compare
MMJJ
_RS07655
-3.2
-15.4
hypothetical protein
compare
MMJJ
_RS00270
-3.2
-4.5
adenosylcobinamide-GDP ribazoletransferase
compare
MMJJ
_RS03190
-3.2
-3.6
phosphopyruvate hydratase
compare
MMJJ
_RS08340
-3.2
-5.6
archaeoflavoprotein AfpA
compare
MMJJ
_RS07000
-3.2
-2.5
TrkH family potassium uptake protein
compare
MMJJ
_RS05930
-3.2
-2.5
cell division protein SepF
compare
MMJJ
_RS00520
-3.2
-7.0
PDGLE domain-containing protein
compare
MMJJ
_RS03760
-3.2
-4.5
hydrogenase maturation nickel metallochaperone HypA
compare
MMJJ
_RS08320
-3.1
-2.3
CDP-diacylglycerol--serine O-phosphatidyltransferase
compare
MMJJ
_RS06915
-3.1
-14.1
helix-turn-helix domain-containing protein
compare
MMJJ
_RS01755
-3.1
-3.4
ferrous iron transport protein B
compare
MMJJ
_RS05950
-3.1
-4.9
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
compare
MMJJ
_RS08055
-3.1
-7.8
methanogenesis marker 14 protein
compare
MMJJ
_RS05065
-3.1
-5.4
(4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase
compare
MMJJ
_RS06875
-3.1
-3.7
hypothetical protein
compare
MMJJ
_RS03615
-3.1
-3.7
cobalt-precorrin-8 methylmutase
compare
MMJJ
_RS04790
-3.1
-5.3
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMJJ
_RS07950
-3.1
-3.6
4Fe-4S binding protein
compare
MMJJ
_RS02935
-3.1
-4.3
DNA-directed RNA polymerase subunit E''
compare
MMJJ
_RS04155
-3.0
-6.9
hypothetical protein
compare
MMJJ
_RS01565
-3.0
-7.5
TIGR00267 family protein
compare
MMJJ
_RS03055
-3.0
-3.6
hypothetical protein
compare
MMJJ
_RS04995
-3.0
-7.7
Tfx family DNA-binding protein
compare
MMJJ
_RS04475
-3.0
-4.3
3,4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMJJ
_RS06725
-3.0
-14.1
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMJJ
_RS06255
-3.0
-8.4
tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3
compare
MMJJ
_RS06840
-3.0
-4.2
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS05490
-3.0
-4.4
imidazole glycerol phosphate synthase subunit HisF
compare
MMJJ
_RS08080
-2.9
-10.0
TIGR00300 family protein
compare
MMJJ
_RS04800
-2.9
-6.4
2-phospho-L-lactate guanylyltransferase
compare
MMJJ
_RS08005
-2.9
-16.8
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMJJ
_RS00195
-2.9
-4.5
precorrin-3B C(17)-methyltransferase
compare
MMJJ
_RS00045
-2.8
-14.9
CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
compare
MMJJ
_RS05225
-2.8
-2.0
Gar1/Naf1 family protein
compare
MMJJ
_RS05070
-2.8
-2.7
DNA primase catalytic subunit PriS
compare
MMJJ
_RS00070
-2.8
-5.3
CooT family nickel-binding protein
compare
MMJJ
_RS08000
-2.8
-10.0
HesA/MoeB/ThiF family protein
compare
MMJJ
_RS03295
-2.8
-16.9
PHP domain-containing protein
compare
MMJJ
_RS07350
-2.8
-4.0
4Fe-4S binding protein
compare
MMJJ
_RS07945
-2.8
-3.7
4Fe-4S binding protein
compare
MMJJ
_RS03060
-2.8
-3.9
methanogenesis marker 7 protein
compare
MMJJ
_RS08095
-2.8
-5.8
cobyric acid synthase CobQ
compare
MMJJ
_RS06375
-2.7
-5.3
UbiX family flavin prenyltransferase
compare
MMJJ
_RS02275
-2.7
-5.0
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS01360
-2.7
-3.0
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMJJ
_RS00040
-2.7
-10.3
CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
compare
MMJJ
_RS04675
-2.7
-6.7
thiamine pyrophosphate-binding protein
compare
MMJJ
_RS04685
-2.7
-9.4
carbamoyltransferase HypF
compare
MMJJ
_RS03005
-2.7
-4.8
Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit
compare
MMJJ
_RS03830
-2.7
-11.0
CBS domain-containing protein
compare
MMJJ
_RS00080
-2.7
-13.7
DUF166 domain-containing protein
compare
MMJJ
_RS00050
-2.7
-12.2
AAA family ATPase
compare
MMJJ
_RS06110
-2.6
-3.0
bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC
compare
MMJJ
_RS07275
-2.6
-4.1
formate--phosphoribosylaminoimidazolecarboxamide ligase
compare
MMJJ
_RS00275
-2.6
-2.7
coenzyme F420-0:L-glutamate ligase
compare
MMJJ
_RS00075
-2.6
-11.4
AAA family ATPase
compare
MMJJ
_RS06180
-2.6
-3.6
tryptophan--tRNA ligase
compare
MMJJ
_RS06905
-2.6
-2.7
hypothetical protein
compare
MMJJ
_RS07660
-2.6
-10.2
carbonic anhydrase
compare
MMJJ
_RS08065
-2.6
-3.3
precorrin-6Y C5,15-methyltransferase (decarboxylating) subunit CbiT
compare
MMJJ
_RS05260
-2.6
-5.8
ATP-grasp domain-containing protein
compare
MMJJ
_RS06185
-2.6
-6.4
cobalamin biosynthesis protein
compare
MMJJ
_RS03635
-2.6
-4.0
methionine--tRNA ligase
compare
MMJJ
_RS06215
-2.6
-5.4
agmatinase
compare
MMJJ
_RS00060
-2.6
-15.8
acetyl-CoA decarbonylase/synthase complex subunit gamma
compare
MMJJ
_RS01865
-2.6
-5.2
peptidyl-tRNA hydrolase Pth2
compare
MMJJ
_RS06380
-2.6
-4.9
signal recognition particle protein Srp54
compare
MMJJ
_RS05810
-2.6
-8.6
precorrin-4 C(11)-methyltransferase
compare
MMJJ
_RS00035
-2.5
-16.5
CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
compare
MMJJ
_RS04730
-2.5
-3.6
tyrosine decarboxylase MfnA
compare
MMJJ
_RS04655
-2.5
-5.5
FAD-dependent oxidoreductase
compare
MMJJ
_RS04595
-2.5
-4.2
hypothetical protein
compare
MMJJ
_RS05995
-2.5
-3.0
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS03620
-2.5
-6.3
DUF2097 domain-containing protein
compare
MMJJ
_RS03630
-2.5
-11.5
AMP phosphorylase
compare
MMJJ
_RS00530
-2.5
-12.1
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS06730
-2.5
-6.6
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS07995
-2.4
-7.7
molybdenum cofactor biosynthesis protein MoaE
compare
MMJJ
_RS05655
-2.4
-7.0
HisA/HisF family protein
compare
MMJJ
_RS00055
-2.4
-9.0
CO dehydrogenase/acetyl-CoA synthase subunit delta
compare
MMJJ
_RS03065
-2.4
-10.7
CBS domain-containing protein
compare
MMJJ
_RS01690
-2.4
-3.9
methanogenesis marker 12 protein
compare
MMJJ
_RS07425
-2.4
-10.9
MBL fold metallo-hydrolase
compare
MMJJ
_RS03800
-2.4
-10.9
aldolase
compare
MMJJ
_RS03865
-2.4
-2.0
phosphoribosyl-AMP cyclohydrolase
compare
MMJJ
_RS08660
-2.4
-3.3
acetylornithine transaminase
compare
MMJJ
_RS00425
-2.4
-3.9
hypothetical protein
compare
MMJJ
_RS06225
-2.4
-2.7
adenosylmethionine decarboxylase
compare
MMJJ
_RS05765
-2.4
-1.2
flagellar protein E
compare
MMJJ
_RS04520
-2.4
-5.6
coenzyme F430 synthase
compare
MMJJ
_RS06220
-2.4
-5.7
polyamine aminopropyltransferase
compare
MMJJ
_RS01345
-2.3
-4.7
(5-formylfuran-3-yl)methyl phosphate synthase
compare
MMJJ
_RS05190
-2.3
-7.1
gamma carbonic anhydrase family protein
compare
MMJJ
_RS03150
-2.3
-6.4
2-phospho-L-lactate transferase
compare
MMJJ
_RS00125
-2.3
-2.9
KEOPS complex subunit Cgi121
compare
MMJJ
_RS08620
-2.3
-3.1
DUF373 family protein
compare
MMJJ
_RS00205
-2.3
-5.4
adenosylcobinamide-phosphate synthase CbiB
compare
MMJJ
_RS00065
-2.3
-11.6
4Fe-4S dicluster domain-containing protein
compare
MMJJ
_RS06930
-2.3
-3.0
type II methionyl aminopeptidase
compare
MMJJ
_RS07650
-2.3
-16.5
formate/nitrite transporter family protein
compare
MMJJ
_RS07725
-2.3
-8.3
DNA primase DnaG
compare
MMJJ
_RS07635
-2.3
-13.2
response regulator transcription factor
compare
MMJJ
_RS07640
-2.3
-17.6
cache domain-containing protein
compare
MMJJ
_RS07155
-2.3
-9.0
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMJJ
_RS03200
-2.3
-2.3
uroporphyrinogen-III synthase
compare
MMJJ
_RS07345
-2.2
-5.6
homocysteine biosynthesis protein
compare
MMJJ
_RS06835
-2.2
-10.3
4Fe-4S binding protein
compare
MMJJ
_RS07370
-2.2
-3.9
tRNA 4-thiouridine(8) synthase ThiI
compare
MMJJ
_RS00475
-2.2
-2.6
bifunctional ornithine acetyltransferase/N-acetylglutamate synthase
compare
MMJJ
_RS06485
-2.2
-3.5
phosphoglycerate kinase
compare
MMJJ
_RS05375
-2.2
-13.8
radical SAM protein
compare
MMJJ
_RS07840
-2.1
-4.8
Glu-tRNA(Gln) amidotransferase subunit GatD
compare
MMJJ
_RS05360
-2.1
-6.5
nickel-responsive transcriptional regulator NikR
compare
MMJJ
_RS00560
-2.1
-3.7
homoisocitrate dehydrogenase
compare
MMJJ
_RS07245
-2.1
-3.8
amidohydrolase family protein
compare
MMJJ
_RS01410
-2.1
-5.7
archaeal proteasome endopeptidase complex subunit beta
compare
MMJJ
_RS06170
-2.1
-8.1
hypothetical protein
compare
MMJJ
_RS01405
-2.1
-1.2
proline--tRNA ligase
compare
MMJJ
_RS09190
-2.1
-2.1
tryptophan synthase subunit beta
compare
MMJJ
_RS03160
-2.1
-13.2
winged helix-turn-helix transcriptional regulator
compare
MMJJ
_RS07360
-2.1
-1.7
TIGR00269 family protein
compare
MMJJ
_RS02055
-2.0
-12.1
GTP 3',8-cyclase MoaA
compare
MMJJ
_RS01475
-2.0
-1.9
signal recognition particle-docking protein FtsY
compare
MMJJ
_RS00355
-2.0
-3.3
ribonuclease P protein component 4
compare
MMJJ
_RS00265
-2.0
-6.3
TIGR02253 family HAD-type hydrolase
compare
MMJJ
_RS00515
-2.0
-10.5
cobalt transporter CbiM
compare
MMJJ
_RS08840
-2.0
-4.1
calcium/sodium antiporter
compare
MMJJ
_RS06785
-2.0
-7.6
RNA ligase partner protein
compare
MMJJ
_RS04970
-2.0
-1.9
DUF655 domain-containing protein
compare
MMJJ
_RS08325
-2.0
-2.2
glycosyltransferase family 2 protein
compare
MMJJ
_RS06270
-1.9
-7.4
dethiobiotin synthase
compare
MMJJ
_RS06050
-1.9
-9.3
molybdopterin molybdotransferase MoeA
compare
MMJJ
_RS04980
-1.9
-4.4
bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase
compare
MMJJ
_RS06010
-1.9
-5.5
hypothetical protein
compare
MMJJ
_RS06175
-1.9
-2.3
DUF1743 domain-containing protein
compare
MMJJ
_RS03815
-1.9
-1.8
nascent polypeptide-associated complex protein
compare
MMJJ
_RS06805
-1.9
-3.0
monovalent cation/H+ antiporter subunit E
compare
MMJJ
_RS06760
-1.8
-4.2
Ni-sirohydrochlorin a,c-diamide synthase
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments