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Experiment set3IT044 for
Methanococcus maripaludis JJ
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formate McAA thiamine dropout
200 most detrimental genes:
gene
name
fitness
t score
description
MMJJ
_RS04415
+2.7
12.3
hypothetical protein
compare
MMJJ
_RS04005
+1.3
9.4
acetate--CoA ligase family protein
compare
MMJJ
_RS08830
+1.0
3.2
hypothetical protein
compare
MMJJ
_RS05685
+0.9
6.1
class III signal peptide-containing protein
compare
MMJJ
_RS08935
+0.8
0.9
TIGR00288 family NYN domain-containing protein
compare
MMJJ
_RS07240
+0.8
7.0
MBL fold metallo-hydrolase
compare
MMJJ
_RS07750
+0.8
1.6
class III signal peptide-containing protein
compare
MMJJ
_RS01855
+0.8
5.2
MBL fold metallo-hydrolase
compare
MMJJ
_RS06675
+0.7
5.1
TIGR01212 family radical SAM protein
compare
MMJJ
_RS06680
+0.7
3.4
DUF366 family protein
compare
MMJJ
_RS05915
+0.6
1.6
multiprotein bridging factor aMBF1
compare
MMJJ
_RS07185
+0.6
1.3
DUF371 domain-containing protein
compare
MMJJ
_RS07015
+0.6
0.9
PFL family protein
compare
MMJJ
_RS06495
+0.6
1.9
hypothetical protein
compare
MMJJ
_RS03835
+0.6
2.7
DUF504 domain-containing protein
compare
MMJJ
_RS03250
+0.6
1.7
DUF2116 family Zn-ribbon domain-containing protein
compare
MMJJ
_RS04955
+0.6
3.0
tRNA pseudouridine(54/55) synthase Pus10
compare
MMJJ
_RS04135
+0.6
2.3
7-cyano-7-deazaguanine synthase QueC
compare
MMJJ
_RS06210
+0.6
2.8
hypothetical protein
compare
MMJJ
_RS08130
+0.6
0.5
translation initiation factor IF-2 subunit gamma
compare
MMJJ
_RS06950
+0.6
3.6
4-demethylwyosine synthase TYW1
compare
MMJJ
_RS07280
+0.5
3.7
phosphomannomutase/phosphoglucomutase
compare
MMJJ
_RS07495
+0.5
3.1
4Fe-4S binding protein
compare
MMJJ
_RS04545
+0.5
1.8
PadR family transcriptional regulator
compare
MMJJ
_RS08100
+0.5
2.5
hypothetical protein
compare
MMJJ
_RS04105
+0.5
4.2
prepilin peptidase
compare
MMJJ
_RS07005
+0.5
2.0
transcription factor S
compare
MMJJ
_RS08525
+0.5
2.8
peptidylprolyl isomerase
compare
MMJJ
_RS07795
+0.5
2.5
cupin domain-containing protein
compare
MMJJ
_RS09300
+0.5
1.1
hypothetical protein
compare
MMJJ
_RS06500
+0.5
3.1
class I SAM-dependent methyltransferase
compare
MMJJ
_RS04965
+0.5
1.0
RNA polymerase Rpb4 family protein
compare
MMJJ
_RS06200
+0.5
0.9
phosphoglycerate dehydrogenase
compare
MMJJ
_RS03445
+0.5
2.4
hypothetical protein
compare
MMJJ
_RS07205
+0.5
2.3
MTH895/ArsE family thioredoxin-like protein
compare
MMJJ
_RS07920
+0.5
2.9
6-carboxytetrahydropterin synthase QueD
compare
MMJJ
_RS03605
+0.5
1.4
TIGR00297 family protein
compare
MMJJ
_RS07025
+0.5
2.5
tRNA (cytidine(56)-2'-O)-methyltransferase
compare
MMJJ
_RS03725
+0.5
1.5
sulfurtransferase TusA family protein
compare
MMJJ
_RS07220
+0.4
3.2
coenzyme F420 hydrogenase subunit beta
compare
MMJJ
_RS06735
+0.4
3.1
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS07225
+0.4
2.5
coenzyme F420 hydrogenase subunit gamma
compare
MMJJ
_RS08515
+0.4
1.7
secondary thiamine-phosphate synthase enzyme YjbQ
compare
MMJJ
_RS08305
+0.4
1.7
peroxiredoxin
compare
MMJJ
_RS01825
+0.4
2.4
DNA repair and recombination protein RadB
compare
MMJJ
_RS07235
+0.4
3.4
coenzyme F420 hydrogenase subunit alpha
compare
MMJJ
_RS07450
+0.4
2.2
hypothetical protein
compare
MMJJ
_RS06810
+0.4
3.1
L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha
compare
MMJJ
_RS06440
+0.4
2.5
DUF4870 domain-containing protein
compare
MMJJ
_RS06280
+0.4
3.0
hypothetical protein
compare
MMJJ
_RS06275
+0.4
1.6
hypothetical protein
compare
MMJJ
_RS07680
+0.4
2.6
glucose-6-phosphate isomerase
compare
MMJJ
_RS06770
+0.4
3.0
hypothetical protein
compare
MMJJ
_RS07210
+0.4
2.7
AmmeMemoRadiSam system protein B
compare
MMJJ
_RS09065
+0.4
2.1
hypothetical protein
compare
MMJJ
_RS03515
+0.4
2.5
GPR1/FUN34/YaaH family transporter
compare
MMJJ
_RS06685
+0.4
3.3
S-layer protein
compare
MMJJ
_RS05975
+0.4
2.2
sulfurtransferase TusA family protein
compare
MMJJ
_RS02270
+0.4
1.3
HEPN domain-containing protein
compare
MMJJ
_RS05530
+0.4
1.3
roadblock/LC7 domain-containing protein
compare
MMJJ
_RS07215
+0.4
2.9
TIGR00341 family protein
compare
MMJJ
_RS06190
+0.4
2.6
7-cyano-7-deazaguanine synthase
compare
MMJJ
_RS00150
+0.4
1.9
DUF2180 family protein
compare
MMJJ
_RS05525
+0.4
2.1
GTP-binding protein
compare
MMJJ
_RS00400
+0.4
1.2
tautomerase family protein
compare
MMJJ
_RS08490
+0.4
1.9
rubrerythrin family protein
compare
MMJJ
_RS06090
+0.4
2.2
hypothetical protein
compare
MMJJ
_RS05520
+0.4
2.5
H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein
compare
MMJJ
_RS00890
+0.4
2.3
coenzyme F420 hydrogenase subunit gamma
compare
MMJJ
_RS07890
+0.4
2.1
pyrimidine dimer DNA glycosylase/endonuclease V
compare
MMJJ
_RS05400
+0.4
1.4
CoA-binding protein
compare
MMJJ
_RS00145
+0.4
2.7
aquaporin family protein
compare
MMJJ
_RS05970
+0.4
0.8
MJ0307 family thioredoxin
compare
MMJJ
_RS07480
+0.4
2.6
FAD-dependent oxidoreductase
compare
MMJJ
_RS06740
+0.4
1.9
energy-coupling factor ABC transporter substrate-binding protein
compare
MMJJ
_RS06745
+0.4
2.0
energy-coupling factor ABC transporter permease
compare
MMJJ
_RS01300
+0.3
2.2
MarR family transcriptional regulator
compare
MMJJ
_RS03070
+0.3
0.8
MetS family NSS transporter small subunit
compare
MMJJ
_RS07230
+0.3
2.1
coenzyme F420-reducing hydrogenase, FrhD protein
compare
MMJJ
_RS07260
+0.3
2.2
PspC domain-containing protein
compare
MMJJ
_RS06460
+0.3
2.0
cytochrome c
compare
MMJJ
_RS04390
+0.3
2.6
rhomboid family intramembrane serine protease
compare
MMJJ
_RS08455
+0.3
1.7
tetratricopeptide repeat protein
compare
MMJJ
_RS06205
+0.3
2.2
EamA family transporter
compare
MMJJ
_RS01100
+0.3
0.5
helix-turn-helix domain-containing protein
compare
MMJJ
_RS03360
+0.3
0.4
hypothetical protein
compare
MMJJ
_RS06515
+0.3
2.2
ribonuclease III
compare
MMJJ
_RS06120
+0.3
2.0
DUF4013 domain-containing protein
compare
MMJJ
_RS06710
+0.3
2.4
TldD/PmbA family protein
compare
MMJJ
_RS06640
+0.3
1.9
YfcE family phosphodiesterase
compare
MMJJ
_RS04610
+0.3
1.4
ribosome assembly RNA-binding protein YhbY
compare
MMJJ
_RS08225
+0.3
1.3
peptidylprolyl isomerase
compare
MMJJ
_RS07270
+0.3
1.8
ribonuclease HII
compare
MMJJ
_RS08285
+0.3
2.1
class I SAM-dependent methyltransferase
compare
MMJJ
_RS05365
+0.3
1.6
DUF2798 domain-containing protein
compare
MMJJ
_RS08520
+0.3
0.7
peptidylprolyl isomerase
compare
MMJJ
_RS01010
+0.3
2.9
right-handed parallel beta-helix repeat-containing protein
compare
MMJJ
_RS09360
+0.3
2.0
hypothetical protein
compare
MMJJ
_RS01590
+0.3
0.5
adenine phosphoribosyltransferase
compare
MMJJ
_RS04815
+0.3
1.4
TIM barrel protein
compare
MMJJ
_RS03905
+0.3
1.2
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS04850
+0.3
1.5
energy-coupling factor transporter transmembrane protein EcfT
compare
MMJJ
_RS06385
+0.3
1.2
hypothetical protein
compare
MMJJ
_RS06585
+0.3
1.9
alanine racemase
compare
MMJJ
_RS09325
+0.3
1.3
hypothetical protein
compare
MMJJ
_RS06535
+0.3
2.2
UPF0104 family protein
compare
MMJJ
_RS07820
+0.3
2.0
bifunctional hexulose-6-phosphate synthase/ribonuclease regulator
compare
MMJJ
_RS07200
+0.3
2.2
MFS transporter
compare
MMJJ
_RS04215
+0.3
2.2
DMT family transporter
compare
MMJJ
_RS04420
+0.3
2.1
type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family
compare
MMJJ
_RS01595
+0.3
1.6
U32 family peptidase
compare
MMJJ
_RS02115
+0.3
1.8
class I SAM-dependent methyltransferase family protein
compare
MMJJ
_RS05500
+0.3
2.4
hypothetical protein
compare
MMJJ
_RS06960
+0.3
2.2
CAP domain-containing protein
compare
MMJJ
_RS07740
+0.3
1.7
DUF2334 domain-containing protein
compare
MMJJ
_RS07695
+0.3
2.2
glycoside hydrolase family 15 protein
compare
MMJJ
_RS05700
+0.3
1.7
metallophosphoesterase
compare
MMJJ
_RS06470
+0.3
1.8
tripartite tricarboxylate transporter permease
compare
MMJJ
_RS06580
+0.3
1.8
alanine dehydrogenase
compare
MMJJ
_RS09405
+0.3
0.7
hypothetical protein
compare
MMJJ
_RS01140
+0.3
1.0
helix-turn-helix domain-containing protein
compare
MMJJ
_RS07010
+0.3
1.3
preprotein translocase subunit Sec61beta
compare
MMJJ
_RS05040
+0.3
1.8
7-carboxy-7-deazaguanine synthase QueE
compare
MMJJ
_RS06285
+0.3
1.4
YchF/TatD family DNA exonuclease
compare
MMJJ
_RS05605
+0.3
0.9
hypothetical protein
compare
MMJJ
_RS05835
+0.3
1.9
bis-aminopropyl spermidine synthase family protein
compare
MMJJ
_RS05695
+0.3
0.9
class III signal peptide-containing protein
compare
MMJJ
_RS02230
+0.3
1.9
hypothetical protein
compare
MMJJ
_RS00635
+0.3
1.8
ABC transporter permease subunit
compare
MMJJ
_RS03575
+0.2
1.1
NUDIX hydrolase
compare
MMJJ
_RS07765
+0.2
1.1
DMT family protein
compare
MMJJ
_RS08315
+0.2
1.7
DNA protection protein DPS
compare
MMJJ
_RS07835
+0.2
1.2
UPF0489 family protein
compare
MMJJ
_RS03450
+0.2
1.2
hypothetical protein
compare
MMJJ
_RS01955
+0.2
1.9
hypothetical protein
compare
MMJJ
_RS01945
+0.2
1.2
cell division ATPase MinD
compare
MMJJ
_RS00335
+0.2
1.0
chemotaxis protein CheW
compare
MMJJ
_RS07815
+0.2
1.6
2-oxoacid:acceptor oxidoreductase family protein
compare
MMJJ
_RS00705
+0.2
1.4
nitrogenase iron protein
compare
MMJJ
_RS07800
+0.2
1.9
AMP-binding protein
compare
MMJJ
_RS09230
+0.2
0.9
hypothetical protein
compare
MMJJ
_RS00640
+0.2
1.8
glycine betaine ABC transporter substrate-binding protein
compare
MMJJ
_RS06550
+0.2
1.6
ABC transporter permease
compare
MMJJ
_RS04240
+0.2
1.8
molybdate ABC transporter substrate-binding protein
compare
MMJJ
_RS02180
+0.2
1.2
DHH family phosphoesterase
compare
MMJJ
_RS06505
+0.2
0.9
prephenate dehydratase
compare
MMJJ
_RS05900
+0.2
1.7
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS06455
+0.2
1.6
YeeE/YedE family protein
compare
MMJJ
_RS08015
+0.2
1.1
HAD family hydrolase
compare
MMJJ
_RS03410
+0.2
1.2
hypothetical protein
compare
MMJJ
_RS05390
+0.2
1.7
tRNA pseudouridine(13) synthase TruD
compare
MMJJ
_RS08195
+0.2
1.1
DUF4186 domain-containing protein
compare
MMJJ
_RS06790
+0.2
1.7
nucleotidyltransferase family protein
compare
MMJJ
_RS06520
+0.2
1.6
TldD/PmbA family protein
compare
MMJJ
_RS06085
+0.2
0.9
proteasome assembly chaperone family protein
compare
MMJJ
_RS01670
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS06045
+0.2
1.3
hypothetical protein
compare
MMJJ
_RS02280
+0.2
1.5
sulfate permease
compare
MMJJ
_RS07915
+0.2
0.9
CBS domain-containing protein
compare
MMJJ
_RS03730
+0.2
0.6
SWIM zinc finger family protein
compare
MMJJ
_RS05200
+0.2
1.5
TIGR04013 family B12-binding domain/radical SAM domain-containing protein
compare
MMJJ
_RS07365
+0.2
1.3
CatB-related O-acetyltransferase
compare
MMJJ
_RS05715
+0.2
1.4
phosphoadenosine phosphosulfate reductase family protein
compare
MMJJ
_RS02160
+0.2
1.2
amino acid ABC transporter permease
compare
MMJJ
_RS01530
+0.2
0.5
YwbE family protein
compare
MMJJ
_RS03375
+0.2
0.9
hypothetical protein
compare
MMJJ
_RS05235
+0.2
1.7
Flp pilus assembly complex ATPase component TadA
compare
MMJJ
_RS03290
+0.2
1.6
amidohydrolase
compare
MMJJ
_RS06720
+0.2
1.2
mechanosensitive ion channel family protein
compare
MMJJ
_RS06765
+0.2
1.5
hypothetical protein
compare
MMJJ
_RS04375
+0.2
0.6
hypothetical protein
compare
MMJJ
_RS07760
+0.2
0.9
GNAT family N-acetyltransferase
compare
MMJJ
_RS08735
+0.2
1.4
hypothetical protein
compare
MMJJ
_RS05405
+0.2
1.4
DNA cytosine methyltransferase
compare
MMJJ
_RS08310
+0.2
0.9
ZIP family metal transporter
compare
MMJJ
_RS07175
+0.2
1.5
DEAD/DEAH box helicase
compare
MMJJ
_RS01745
+0.2
0.9
metal-dependent transcriptional regulator
compare
MMJJ
_RS04070
+0.2
1.6
DUF2341 domain-containing protein
compare
MMJJ
_RS05585
+0.2
1.1
hypothetical protein
compare
MMJJ
_RS06430
+0.2
0.8
haloacid dehalogenase
compare
MMJJ
_RS08375
+0.2
1.2
ferritin
compare
MMJJ
_RS04430
+0.2
1.2
purine NTPase
compare
MMJJ
_RS04745
+0.2
0.8
cyclase family protein
compare
MMJJ
_RS05090
+0.2
0.8
MGMT family protein
compare
MMJJ
_RS04300
+0.2
1.1
hypothetical protein
compare
MMJJ
_RS03345
+0.2
0.7
hypothetical protein
compare
MMJJ
_RS08045
+0.2
1.3
transporter substrate-binding domain-containing protein
compare
MMJJ
_RS00695
+0.2
1.0
P-II family nitrogen regulator
compare
MMJJ
_RS08210
+0.2
1.6
hypothetical protein
compare
MMJJ
_RS08880
+0.2
0.6
IMPACT family protein
compare
MMJJ
_RS05410
+0.2
0.9
RecB-family nuclease
compare
MMJJ
_RS08165
+0.2
0.8
thermonuclease family protein
compare
MMJJ
_RS01395
+0.2
0.7
DUF1894 domain-containing protein
compare
MMJJ
_RS08445
+0.2
0.9
cell division ATPase MinD
compare
MMJJ
_RS05510
+0.2
1.1
archaellum operon transcriptional activator EarA family protein
compare
MMJJ
_RS05690
+0.2
1.5
hypothetical protein
compare
MMJJ
_RS08275
+0.2
1.5
iron ABC transporter substrate-binding protein
compare
MMJJ
_RS07810
+0.2
1.0
3-methyl-2-oxobutanoate dehydrogenase subunit VorB
compare
MMJJ
_RS04530
+0.2
1.1
iron export ABC transporter permease subunit FetB
compare
MMJJ
_RS00630
+0.2
1.0
betaine/proline/choline family ABC transporter ATP-binding protein
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments