Experiment set3IT043 for Sinorhizobium meliloti 1021

Compare to:

LB with Cisplatin 0.001 mg/ml

200 most important genes:

  gene name fitness t score description  
SMc02863 -5.0 -4.6 recombination protein F compare
SMc02753 -4.7 -1.4 PTS system transporter subunit IIA compare
SMc00726 -4.5 -1.0 thiol:disulfide interchange redox-active center transmembrane protein compare
SMc00619 -4.4 -1.9 hypothetical protein compare
SMc02635 -4.4 -9.0 DNA repair protein RecO conserved
SMc01235 -4.3 -15.1 excinuclease ABC subunit A compare
SMc02485 -4.2 -1.5 signal peptide protein compare
SMc02237 -3.9 -16.3 DNA damage response helicase, ligase-associated (from data) conserved
SMc01461 -3.9 -7.5 DNA helicase II protein compare
SMc03763 -3.8 -3.7 cytosine-specific methyltransferase compare
SMc02850 -3.8 -3.3 DNA polymerase I compare
SMc00010 -3.7 -1.8 cytochrome C oxidase polypeptide I transmembrane protein compare
SMc02147 -3.7 -7.3 phosphate regulon sensor histidine kinase transmembrane protein compare
SMc00602 -3.5 -5.4 excinuclease ABC subunit C compare
SMc02908 -3.5 -3.9 recombination protein RecR compare
SMc01877 -3.4 -6.4 DNA repair protein compare
SMc00239 -3.3 -1.0 hypothetical protein compare
SMc04085 -3.2 -5.8 hypothetical protein compare
SMc00963 -3.2 -3.7 hypothetical protein compare
SMc02144 -3.2 -5.4 phosphate ABC transporter permease compare
SMc03789 -3.1 -5.8 hypothetical protein conserved
SMc03790 -3.0 -4.7 hypothetical protein compare
SMc00012 -3.0 -1.5 cytochrome C oxidase assembly protein compare
SMa0789 -3.0 -3.6 GntR family transcriptional regulator compare
SMc02084 -2.9 -0.9 biopolymer transport transmembrane protein compare
SMc02236 -2.9 -3.8 DNA repair nuclease, ligase-associated (TIGR04123) (from data) conserved
SMc04296 -2.9 -0.9 cell division protein FtsZ compare
SMc00073 -2.8 -2.4 hypothetical protein compare
SMc02641 -2.8 -4.2 UDP-glucose 6-dehydrogenase compare
SM_b21480 -2.8 -1.0 hypothetical protein compare
SMc01880 -2.7 -2.7 pantoate--beta-alanine ligase compare
SMc01187 -2.7 -1.8 rare lipoprotein A compare
SMc00556 -2.7 -4.8 DNA repair protein RadA compare
SMa2289 -2.7 -1.3 hypothetical protein compare
SMc03788 -2.7 -12.6 DNA polymerase III subunit alpha conserved
SMc01881 -2.6 -2.6 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SMc03978 -2.6 -4.3 transketolase compare
SMc02149 -2.6 -1.6 hypothetical protein compare
SMc02505 -2.5 -1.5 hypothetical protein compare
SMc05020 -2.5 -1.7 entericidin A precursor compare
SMc00302 -2.5 -2.1 hypothetical protein compare
SMc03967 -2.4 -1.2 Holliday junction resolvase compare
SMc00228 -2.4 -9.0 ATP-dependent DNA helicase RecG conserved
SMc02234 -2.4 -1.7 hypothetical protein compare
SMa0848 -2.3 -3.2 hypothetical protein compare
SMc02631 -2.3 -1.4 hypothetical protein compare
SMc01845 -2.3 -1.8 transglycosylase transmembrane protein compare
SMc02901 -2.3 -0.7 hypothetical protein compare
SMc03127 -2.3 -1.6 ABC transporter permease compare
SMc02114 -2.3 -3.2 hypothetical protein compare
SMc02140 -2.2 -1.6 phosphate regulon transcriptional regulatory protein compare
SMc02909 -2.2 -1.6 transglycosylase transmembrane protein compare
SMa0740 -2.2 -2.0 hypothetical protein compare
SMc02142 -2.2 -5.6 phosphate transporter ATP-binding protein compare
SMc02362 -2.2 -2.7 cytochrome c-type biogenesis protein CcmE compare
SMa0776 -2.2 -1.8 TRm23b IS ATP-binding protein compare
SMc03053 -2.2 -0.9 flagellar biosynthesis protein FliQ compare
SM_b20086 -2.2 -1.5 hypothetical protein compare
SMc01280 -2.1 -1.6 protease compare
SMa0905 -2.0 -1.1 hypothetical protein compare
SMc02495 -2.0 -0.8 translaldolase compare
SMc00296 -2.0 -6.5 POLY3-hydroxybutyrate polymerase compare
SMc02102 -2.0 -3.0 hypothetical protein compare
SMc01147 -1.9 -2.5 coproporphyrinogen III oxidase compare
SMc01242 -1.9 -2.3 signal peptide protein compare
SMc00295 -1.9 -1.0 hypothetical protein compare
SMa0992 -1.9 -2.2 hypothetical protein compare
SMc02260 -1.9 -1.3 ABC transporter ATP-binding protein compare
SMc02868 -1.9 -3.1 multidrug efflux system protein compare
SMa0349 -1.9 -1.2 hypothetical protein compare
SMc00914 -1.9 -4.9 oxidoreductase compare
SM_b20323 -1.9 -1.1 transcriptional regulator compare
SMc00492 -1.8 -0.8 hypothetical protein compare
SM_b20105 -1.8 -1.5 transcriptional regulator compare
SMc03159 -1.8 -1.9 ABC transporter ATP-binding protein compare
SMa1095 -1.8 -0.6 hypothetical protein compare
SMc01183 -1.8 -1.4 LexA repressor compare
SMc02363 -1.8 -2.9 cytochrome C-type biogenesis transmembrane protein compare
SM_b20026 -1.8 -0.9 hypothetical protein compare
SMc02856 -1.8 -8.6 penicillin-binding protein compare
SMc04231 -1.8 -4.8 excinuclease ABC subunit B compare
SMc01360 -1.7 -2.5 aspartate carbamoyltransferase catalytic subunit compare
SMc04391 -1.7 -1.2 3-ketoacyl-ACP reductase compare
SMc02451 -1.7 -1.0 hypothetical protein compare
SMc00928 -1.7 -1.0 signal peptide protein compare
SM_b21523 -1.7 -2.5 cell division inhibitor protein compare
SMc01501 -1.7 -2.2 mannitol 2-dehydrogenase compare
SMc03941 -1.7 -1.5 hypothetical protein compare
SMa2281 -1.7 -1.6 hypothetical protein compare
SMc03242 -1.7 -2.6 GTP-binding protein compare
SMc01850 -1.7 -2.2 hypothetical protein compare
SMc02833 -1.7 -1.6 penicillin-insensitive murein endopeptidase compare
SMc02867 -1.7 -2.5 multidrug-efflux system transmembrane protein compare
SMc02583 -1.6 -3.6 hypothetical protein compare
SMc02564 -1.6 -1.6 LysM domain/BON superfamily protein compare
SMc00650 -1.6 -1.1 hypothetical protein compare
SMc00981 -1.6 -3.3 ferredoxin protein compare
SMc00760 -1.5 -1.9 recombinase A compare
SMc02484 -1.5 -2.8 amino acid efflux transmembrane protein compare
SMc00970 -1.5 -2.1 exodeoxyribonuclease VII small subunit compare
SMc00555 -1.5 -0.9 colicin V production transmembrane protein compare
SM_b21454 -1.5 -1.3 hypothetical protein compare
SMc00712 -1.5 -1.1 hypothetical protein compare
SM_b20750 -1.5 -1.3 dehydrogenase compare
SMc01315 -1.5 -1.1 hypothetical protein compare
SMc03249 -1.5 -1.2 hypothetical protein compare
SMc02683 -1.5 -1.5 hypothetical protein compare
SMa0087 -1.5 -1.5 hypothetical protein compare
SMc01220 -1.4 -3.7 lipopolysaccharide core biosynthesis glycosyl transferase compare
SMc03092 -1.4 -2.0 transcriptional regulator compare
SMc01569 -1.4 -1.1 carbamoyl phosphate synthase small subunit compare
SMa2349 -1.4 -1.9 xanthine dehydrogenase iron-sulfur-binding subunit compare
SMc02046 -1.4 -1.5 hypothetical protein compare
SMc00580 -1.4 -2.9 4-hydroxythreonine-4-phosphate dehydrogenase compare
SMc04330 -1.4 -1.2 trimethylamine methyltransferase compare
SM_b20374 -1.4 -2.7 substrate-binding protein compare
SMc02145 -1.3 -0.8 signal peptide protein compare
SMc02861 -1.3 -1.3 phosphate transporter compare
SMc00053 -1.3 -0.5 monovalent cation/H+ antiporter subunit C compare
SMc01770 -1.3 -1.3 serine hydroxymethyltransferase compare
SMc01447 -1.3 -0.7 hypothetical protein compare
SM_b21347 -1.3 -1.1 pectin degradation protein compare
SMc02980 -1.3 -0.8 hypothetical protein compare
SMc04220 -1.2 -0.7 transcriptional regulator compare
SMa0748 -1.2 -0.9 MucR family transcriptional regulator compare
SMc04024 -1.2 -3.5 membrane-bound lytic murein transglycosylase compare
SMa0872 -1.2 -2.2 hypothetical protein compare
SMc02164 -1.2 -1.3 fructokinase compare
SM_b20452 -1.2 -1.5 hypothetical protein compare
SM_b21172 -1.2 -2.9 hypothetical protein compare
SMa0886 -1.2 -1.0 hypothetical protein compare
SMc01208 -1.2 -1.3 peptidyl-prolyl cis-trans isomerase B protein compare
SMc02609 -1.2 -3.7 transcriptional regulator compare
SM_b20880 -1.2 -4.0 ATP-dependent RNA helicase compare
SMc00876 -1.2 -3.9 ATP-binding MRP protein compare
SMc02719 -1.2 -0.8 transposase compare
SMc02143 -1.2 -2.2 phosphate ABC transporter permease compare
SM_b20218 -1.2 -2.4 sensor histidine kinase compare
SM_b21395 -1.2 -1.2 hypothetical protein compare
SMa1323 -1.2 -1.4 Transcription regulator compare
SMc04319 -1.2 -1.2 hypothetical protein compare
SMc00024 -1.1 -2.2 chromosome partition protein compare
SMc00948 -1.1 -3.9 glutamine synthetase compare
SMa5023 -1.1 -2.5 hypothetical protein compare
SMc01438 -1.1 -3.0 protease precursor signal peptide protein compare
SMa0085 -1.1 -1.7 dehydrogenase compare
SMa1711 -1.1 -2.7 arginase compare
SMc03899 -1.1 -0.5 hypothetical protein compare
SMa1570 -1.1 -0.8 PilA2 pilus assembly protein compare
SMc00709 -1.1 -1.9 hypothetical protein compare
SM_b21218 -1.1 -2.1 glucosamine-6-phosphate deaminase, isomerizing (EC 3.5.99.6) (from data) compare
SMc02894 -1.1 -1.6 hypothetical protein compare
SMc02201 -1.1 -1.7 hypothetical protein compare
SMa1118 -1.1 -0.9 HspC2 heat shock protein compare
SM_b21459 -1.1 -1.9 sugar uptake ABC transporter permease compare
SMa1878 -1.1 -1.5 transposase compare
SMc03128 -1.1 -1.8 ABC transporter permease compare
SMc00191 -1.1 -1.0 hypothetical protein compare
SMc01204 -1.1 -4.6 transmembrane oxidoreductase compare
SMa5011 -1.1 -1.5 oxidoreductase compare
SMc04344 -1.0 -0.8 signal peptide protein compare
SMc01370 -1.0 -1.1 response regulator PleD compare
SMc01200 -1.0 -2.9 hypothetical protein compare
SM_b20042 -1.0 -1.9 hypothetical protein compare
SMc00450 -1.0 -1.1 protoheme IX farnesyltransferase compare
SMa0412 -1.0 -1.5 hypothetical protein compare
SMc00451 -1.0 -3.3 processing protease compare
SM_b21212 -1.0 -1.4 hypothetical protein compare
SMc02799 -1.0 -1.2 16S rRNA methyltransferase GidB compare
SM_b20690 -1.0 -1.0 hypothetical protein compare
SMa2089 -1.0 -1.9 hypothetical protein compare
SM_b20509 -1.0 -1.2 transcriptional regulator compare
SM_b22001 -1.0 -0.9 hypothetical protein compare
SMc00593 -1.0 -1.7 hypothetical protein compare
SMa0343 -1.0 -1.4 hypothetical protein compare
SMc02738 -1.0 -3.8 glycine betaine transport system permease ABC transporter protein compare
SM_b21358 -1.0 -2.8 hypothetical protein compare
SM_b20665 -1.0 -1.8 partial transposase of insertion sequence ISRm17 protein compare
SM_b20822 -1.0 -2.8 cell surface polysaccharide export ABC-2 transporter permease, close relative to wzm1Y20833 compare
SMc04189 -1.0 -1.8 hypothetical protein compare
SMc01635 -1.0 -1.6 oxidoreductase compare
SMa5031 -1.0 -1.1 hypothetical protein compare
SMc01146 -1.0 -1.8 deoxyribonucleotide triphosphate pyrophosphatase compare
SM_b20450 -1.0 -5.2 regulatory protein compare
SMc02865 -1.0 -1.4 acetyltransferase compare
SM_b20148 -1.0 -2.8 transcriptional regulator compare
SMc00067 -1.0 -3.4 outer-membranne lipoprotein compare
SMc00982 -1.0 -1.9 dioxygenase compare
SMc00511 -1.0 -2.4 D-ribulose-5-phosphate 3-epimerase compare
SMc02312 -1.0 -1.5 zinc-binding protein compare
SM_b20687 -1.0 -2.2 hypothetical protein compare
SMc00006 -0.9 -1.2 hypothetical protein compare
SM_b21115 -0.9 -1.2 response regulator protein compare
SMc04008 -0.9 -1.0 hypothetical protein compare
SMc02266 -0.9 -0.9 hypothetical protein compare
SMc02724 -0.9 -1.6 hypothetical protein compare
SMa0846 -0.9 -0.9 transposase, fragment compare
SMc01368 -0.9 -2.6 transport transmembrane protein compare
SM_b21035 -0.9 -2.3 hypothetical protein compare
SM_b20547 -0.9 -0.6 hypothetical protein compare


Specific Phenotypes

For 6 genes in this experiment

For stress Cisplatin in Sinorhizobium meliloti 1021

For stress Cisplatin across organisms