Experiment set3IT043 for Sinorhizobium meliloti 1021

Compare to:

LB with Cisplatin 0.001 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
SMc02112 +4.1 23.0 hypothetical protein compare
SMc00647 +3.5 12.8 ribosomal large subunit pseudouridine synthase compare
SMc04454 +3.4 16.0 ABC transporter ATP-binding protein compare
SMc00150 +3.2 27.2 hypothetical protein compare
SMc04382 +3.2 27.5 beta-(1,2)-glucan production associated transmembrane protein compare
SMc03900 +3.2 20.4 cyclic beta-1,2-glucan ABc transporter compare
SMc00349 +3.0 16.9 GTP-binding protein LepA compare
SMc02367 +2.9 24.2 sensor histidine kinase transmembrane protein compare
SMc03069 +2.9 7.7 6-phosphogluconolactonase compare
SMc02366 +2.9 19.3 transcriptional regulator compare
SMc04094 +2.8 5.2 hypothetical protein compare
SMc02365 +2.7 10.8 protease precursor protein compare
SMc04003 +2.5 4.1 50S ribosomal protein L36 compare
SMc02695 +2.4 9.1 GTP-dependent nucleic acid-binding protein EngD compare
SMc02659 +2.4 5.3 GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase) protein compare
SMc02640 +2.4 7.1 UDP-glucuronic acid epimerase compare
SMc03855 +2.4 4.1 hypothetical protein compare
SMc03826 +2.4 4.6 argininosuccinate synthase compare
SMc00458 +2.3 15.0 transcriptional regulator compare
SMc00761 +2.2 13.4 oxidoreductase compare
SMc02434 +2.2 4.1 hypothetical protein compare
SMc00320 +2.2 7.1 ribosome-binding factor A compare
SMc02137 +2.1 5.3 ornithine carbamoyltransferase compare
SMc00495 +2.1 4.0 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc00622 +2.0 8.8 ribonuclease D protein compare
SMc00131 +2.0 13.4 transcriptional regulator compare
SMc02497 +2.0 2.5 hypothetical protein compare
SMc01858 +1.9 1.9 S-adenosyl-methyltransferase MraW compare
SMc04235 +1.8 6.1 tRNA-dihydrouridine synthase A compare
SMc02714 +1.8 2.4 hypothetical protein compare
SMc00505 +1.8 1.9 hypothetical protein compare
SMc00070 +1.8 4.5 signal peptide protein compare
SMc01907 +1.8 10.4 hypothetical protein compare
SMc00403 +1.8 6.1 NOL1/NOP2/SUN family signature protein compare
SMc00129 +1.8 8.3 sensor histidine kinase compare
SMc03229 +1.7 1.7 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
SMc00329 +1.7 2.7 iron response regulator protein compare
SMc00522 +1.7 11.0 ATP-dependent RNA helicase compare
SMc03066 +1.7 2.7 hypothetical protein compare
SM_b20725 +1.7 2.3 hypothetical protein compare
SMc00351 +1.7 2.2 hypothetical protein compare
SMc02713 +1.7 2.4 RNA polymerase sigma-E factor (sigma-24) protein compare
SMc00038 +1.6 2.9 hypothetical protein compare
SMc00482 +1.6 4.1 hypothetical protein compare
SMc04001 +1.6 1.6 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc04000 +1.5 2.1 hypothetical protein compare
SMc00565 +1.5 1.2 50S ribosomal protein L9 compare
SMc03996 +1.5 4.8 thiamine-phosphate pyrophosphorylase compare
SMc00496 +1.5 1.4 hypothetical protein compare
SMc01124 +1.5 8.2 PII uridylyl-transferase compare
SM_b20413 +1.4 1.6 hypothetical protein compare
SMa1073 +1.4 2.0 TRm23b IS ATP-binding protein compare
SMc02058 +1.4 3.5 YAJC protein compare
SMc03931 +1.4 10.2 sarcosine oxidase subunit alpha compare
SMc01223 +1.4 1.8 transcriptional regulator compare
SM_b21374 +1.4 3.1 tagatose kinase (EC 2.7.1.101) (from data) compare
SMc02121 +1.4 1.5 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, ATPase component (from data) compare
SMc01222 +1.4 5.9 lipopolysaccharide core biosynthesis glycosyl transferase compare
SMc01613 +1.4 3.3 ribose-5-phosphate isomerase B compare
SMc00566 +1.4 3.0 hypothetical protein compare
SMc01698 +1.4 6.1 oxidoreductase compare
SMc03111 +1.4 6.1 mannose 6-phosphate isomerase (EC 5.3.1.8) (from data) compare
SMc03863 +1.4 1.8 50S ribosomal protein L19 compare
SM_b21452 +1.3 2.8 hypothetical protein compare
SMc00648 +1.3 5.3 hypothetical protein compare
SMc02858 +1.3 0.6 chaperone protein DnaJ compare
SMc00321 +1.3 5.4 tRNA pseudouridine synthase B compare
SMc01099 +1.3 1.8 tRNA pseudouridine synthase A compare
SMc03836 +1.3 1.3 acyl-CoA thioesterase i protein compare
SMc02503 +1.3 4.0 hypothetical protein compare
SMc02854 +1.3 7.0 signal peptide protein compare
SM_b20613 +1.3 5.1 C4-dicarboxylate transport transcriptional regulator compare
SMa1430 +1.3 3.5 Dehydrogenase, Zn-dependent compare
SMc00618 +1.3 6.9 polyphosphate kinase compare
SM_b20884 +1.3 1.4 hypothetical protein compare
SMc03933 +1.3 8.0 sarcosine oxidase subunit B protein compare
SM_b21040 +1.2 2.3 oligopeptidemurein peptide ABC transporter ATP-binding protein compare
SM_b21170 +1.2 3.3 guanylate kinase compare
SMc02138 +1.2 4.7 acetylornithine transaminase compare
SMc00802 +1.2 1.0 hypothetical protein compare
SMc02576 +1.2 1.1 acetyltransferase compare
SMc03880 +1.2 6.1 hypothetical protein compare
SMc00877 +1.2 6.5 transcriptional regulator compare
SMc00727 +1.2 4.8 3-hydroxybutyryl-CoA dehydrogenase compare
SMc00998 +1.2 5.5 signal peptide protein compare
SMc01206 +1.2 2.1 queuine tRNA-ribosyltransferase compare
SMc00194 +1.2 2.8 hypothetical protein compare
SM_b21397 +1.1 1.2 hypothetical protein compare
SMa0787 +1.1 1.7 transposase, fragment compare
SMc02757 +1.1 2.8 hypothetical protein compare
SMc02765 +1.1 5.8 tryptophan synthase subunit alpha compare
SMc01933 +1.1 1.2 hypothetical protein compare
SMc04090 +1.1 2.5 sun protein compare
SMc01275 +1.1 5.4 ribosomal large subunit pseudouridine synthase C protein compare
SMc01930 +1.1 1.1 hypothetical protein compare
SMc02269 +1.1 4.7 capsular polysaccharide biosynthesis/export protein compare
SM_b21431 +1.1 4.4 hypothetical protein compare
SMc04174 +1.1 1.4 signal peptide protein compare
SMc00176 +1.1 3.3 hypothetical protein compare
SMc02384 +1.1 5.4 glycosyltransferase transmembrane protein compare
SMa2020 +1.1 3.6 Transcriptional regulator compare
SMa1700 +1.1 1.0 hypothetical protein compare
SM_b21551 +1.0 0.9 hypothetical protein compare
SMc02169 +1.0 1.5 ABC transporter ATP-binding protein compare
SMc01023 +1.0 1.8 triosephosphate isomerase compare
SMc02385 +1.0 2.6 hypothetical protein compare
SMc00788 +1.0 3.2 peptide ABC transporter permease compare
SMc04002 +1.0 3.1 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc02246 +1.0 0.6 hypothetical protein compare
SMc03930 +1.0 1.2 sarcosine oxidase subunit gamma compare
SMc01801 +1.0 2.2 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SMc02826 +1.0 3.4 transcriptional regulator compare
SMc05015 +1.0 1.4 recombinase compare
SMc00174 +1.0 4.5 hypothetical protein compare
SMc01727 +1.0 3.0 hypothetical protein compare
SMc02895 +1.0 3.1 hypothetical protein compare
SMc03827 +1.0 2.7 amino acid efflux transmembrane protein compare
SM_b21266 +1.0 3.6 hypothetical protein compare
SMc03289 +1.0 2.4 hypothetical protein compare
SMc04199 +1.0 3.3 hypothetical protein compare
SM_b20261 +1.0 1.8 malate dehydrogenase compare
SM_b21432 +1.0 2.7 iron uptake ABC transporter substrate-binding protein precursor compare
SMc02649 +1.0 1.6 arsenate reductase compare
SM_b20964 +1.0 2.4 Ahp/CTSA family anti-oxidant protein compare
SMc02975 +1.0 4.3 phosphoenolpyruvate carboxykinase regulator transcription regulator protein compare
SM_b21253 +1.0 3.4 hypothetical protein compare
SMc03932 +1.0 2.2 sarcosine oxidase subunit delta compare
SMc02220 +1.0 2.7 hypothetical protein compare
SMc04298 +1.0 1.6 hypothetical protein compare
SMc00061 +0.9 2.5 hypothetical protein compare
SMc00494 +0.9 1.1 phosphoribosylformylglycinamidine synthase subunit PurS compare
SMc03795 +0.9 1.2 isopropylmalate isomerase small subunit compare
SMc04264 +0.9 1.3 transcriptional regulator compare
SMc02886 +0.9 1.0 signal peptide protein compare
SMc04088 +0.9 4.1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
SMc04441 +0.9 1.3 hypothetical protein compare
SM_b21633 +0.9 0.9 enoyl-CoA hydratase compare
SMa0674 +0.9 0.9 hypothetical protein compare
SMa1310 +0.9 1.7 VirB7-like protein compare
SM_b21429 +0.9 4.2 iron ABC transporter ATP-binding protein compare
SMa0643 +0.9 1.0 transposase compare
SMc01826 +0.9 1.8 ABC transporter permease compare
SMc01916 +0.9 1.3 signal peptide protein compare
SMc02241 +0.9 3.4 hypothetical protein compare
SMc01131 +0.9 1.8 hypothetical protein compare
SMc00883 +0.9 3.8 L-arabinolactonase/D-galactonolactonase (EC 3.1.1.15; EC 3.1.1.25) (from data) compare
SMc00952 +0.9 3.0 hypothetical protein compare
SMa0834 +0.9 3.7 FdxB ferredoxin III compare
SMc02273 +0.9 7.4 fatty acid synthase transmembrane protein compare
SMc01153 +0.9 1.2 enoyl-CoA hydratase compare
SMc01440 +0.9 3.2 hydrolase serine protease transmembrane protein compare
SMc00241 +0.9 1.1 transcriptional regulator compare
SMc02173 +0.9 1.2 hypothetical protein compare
SMc00344 +0.9 2.1 hypothetical protein compare
SMc01769 +0.9 6.1 hypothetical protein compare
SMc01089 +0.9 0.8 hypothetical protein compare
SMa1033 +0.9 2.7 hypothetical protein compare
SMc02989 +0.9 1.0 hypothetical protein compare
SMc00501 +0.9 2.5 hypothetical protein compare
SM_b21428 +0.9 3.5 dTDP-4-dehydrorhamnose 3,5-epimerase compare
SMa0286 +0.9 0.9 hypothetical protein compare
SM_b20697 +0.9 3.8 peptidase, arginine utilization protein RocB compare
SMa0545 +0.9 3.0 hypothetical protein compare
SMc00865 +0.9 2.2 hypothetical protein compare
SMc02247 +0.9 0.8 signal peptide protein compare
SMc03175 +0.9 2.9 nucleoside hydrolase compare
SMc03015 +0.9 5.0 transcriptional regulator compare
SMc03184 +0.9 0.6 PH adaptation potassium efflux system G transmembrane protein compare
SM_b21256 +0.8 3.5 nucleotide sugar oxidase compare
SM_b21580 +0.8 0.8 hypothetical protein compare
SMa1696 +0.8 4.1 Sensor histidine kinase compare
SMc00959 +0.8 1.5 hypothetical protein compare
SM_b21265 +0.8 3.6 glycosyltransferase compare
SMc00711 +0.8 2.4 cyclohexadienyl dehydrogenase compare
SMa2195 +0.8 2.9 ABC transporter ATP-binding protein compare
SMc02287 +0.8 2.6 DNA-invertase compare
SMc01424 +0.8 1.8 nitrile hydratase subunit alpha protein compare
SMc00404 +0.8 0.7 hypothetical protein compare
SMc00325 +0.8 3.4 hypothetical protein compare
SMc02319 +0.8 1.4 hypothetical protein compare
SM_b21028 +0.8 1.5 hypothetical protein compare
SMc00588 +0.8 1.3 L-arabinose 1-dehydrogenase; D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48) (from data) compare
SMc00718 +0.8 1.6 hypothetical protein compare
SMc05009 +0.8 1.4 nodulation protein NolR compare
SM_b21430 +0.8 4.2 iron ABC transporter permease compare
SM_b21002 +0.8 2.8 methionine aminopeptidase compare
SMa0293 +0.8 1.7 hypothetical protein compare
SMc02565 +0.8 4.2 hypothetical protein compare
SMc01021 +0.8 2.0 hypothetical protein compare
SMa5014 +0.8 1.6 hypothetical protein compare
SMc00507 +0.8 1.0 hypothetical protein compare
SM_b20255 +0.8 2.0 hypothetical protein compare
SMc04051 +0.8 0.7 RNA polymerase sigma-E factor (sigma-24) protein compare
SMc02490 +0.8 2.6 hypothetical protein compare
SMc04047 +0.8 2.7 pseudoazurin (blue copper protein) compare
SMc00455 +0.8 2.1 hypothetical protein compare
SMc01203 +0.8 1.9 hypothetical protein compare
SM_b20722 +0.8 2.4 two-component response regulator protein compare
SMc02056 +0.8 2.7 hypothetical protein compare
SMc03279 +0.8 1.4 transposase number 2 for insertion sequence ISRM28 compare


Specific Phenotypes

For 6 genes in this experiment

For stress Cisplatin in Sinorhizobium meliloti 1021

For stress Cisplatin across organisms