Experiment set3IT042 for Sinorhizobium meliloti 1021

Compare to:

LB with Cisplatin 0.0005 mg/ml

200 most important genes:

  gene name fitness t score description  
SMc02863 -4.8 -3.4 recombination protein F compare
SMc00073 -4.8 -2.6 hypothetical protein compare
SMc02753 -4.7 -1.6 PTS system transporter subunit IIA compare
SMc02908 -4.7 -5.6 recombination protein RecR compare
SMc02115 -4.6 -1.1 hypothetical protein compare
SMc00619 -4.5 -2.1 hypothetical protein compare
SMc01461 -4.4 -9.5 DNA helicase II protein compare
SMc01235 -4.3 -15.9 excinuclease ABC subunit A compare
SMc02363 -4.1 -2.8 cytochrome C-type biogenesis transmembrane protein compare
SMc02505 -3.9 -1.3 hypothetical protein compare
SMc02635 -3.9 -7.6 DNA repair protein RecO conserved
SMc01147 -3.8 -5.2 coproporphyrinogen III oxidase compare
SMc00010 -3.8 -2.0 cytochrome C oxidase polypeptide I transmembrane protein compare
SMa1770 -3.7 -1.3 hypothetical protein compare
SMc01880 -3.7 -2.5 pantoate--beta-alanine ligase compare
SMc02140 -3.7 -1.8 phosphate regulon transcriptional regulatory protein compare
SM_b20413 -3.6 -1.2 hypothetical protein compare
SMc03967 -3.4 -1.4 Holliday junction resolvase compare
SMc02236 -3.3 -6.8 DNA repair nuclease, ligase-associated (TIGR04123) (from data) conserved
SMc02237 -3.3 -13.9 DNA damage response helicase, ligase-associated (from data) conserved
SMc04330 -3.3 -3.0 trimethylamine methyltransferase compare
SMc00928 -3.2 -1.1 signal peptide protein compare
SMc02147 -3.2 -10.1 phosphate regulon sensor histidine kinase transmembrane protein compare
SMc00691 -3.1 -3.8 site-specific tyrosine recombinase XerD compare
SMc00492 -3.0 -1.0 hypothetical protein compare
SMc00963 -3.0 -3.8 hypothetical protein compare
SMc02641 -3.0 -3.9 UDP-glucose 6-dehydrogenase compare
SMc02867 -3.0 -5.2 multidrug-efflux system transmembrane protein compare
SMc04296 -3.0 -1.0 cell division protein FtsZ compare
SM_b20948 -2.9 -1.3 glucosyltransferase compare
SM_b20323 -2.9 -1.4 transcriptional regulator compare
SMc01568 -2.9 -1.3 hypothetical protein compare
SMc02145 -2.9 -1.0 signal peptide protein compare
SMc00556 -2.9 -6.0 DNA repair protein RadA compare
SMc00760 -2.8 -4.0 recombinase A compare
SMc02909 -2.8 -2.2 transglycosylase transmembrane protein compare
SMc02144 -2.8 -4.8 phosphate ABC transporter permease compare
SMc01850 -2.7 -3.2 hypothetical protein compare
SMc00800 -2.7 -1.8 hypothetical protein compare
SMc00302 -2.7 -2.7 hypothetical protein compare
SMc00856 -2.7 -1.1 hypothetical protein compare
SM_b20302 -2.6 -2.3 hypothetical protein compare
SMc03978 -2.6 -3.8 transketolase compare
SMc04231 -2.6 -6.5 excinuclease ABC subunit B compare
SMc00602 -2.5 -4.0 excinuclease ABC subunit C compare
SMc00024 -2.4 -3.9 chromosome partition protein compare
SMc02142 -2.4 -5.3 phosphate transporter ATP-binding protein compare
SMc01877 -2.4 -4.9 DNA repair protein compare
SMa0789 -2.3 -4.0 GntR family transcriptional regulator compare
SMa1174 -2.3 -1.8 hypothetical protein compare
SMc03763 -2.3 -3.0 cytosine-specific methyltransferase compare
SMc02861 -2.3 -2.4 phosphate transporter compare
SMa0106 -2.2 -3.8 ABC transporter permease compare
SMc00802 -2.2 -0.9 hypothetical protein compare
SMc02582 -2.2 -2.6 hypothetical protein compare
SMc03788 -2.2 -12.0 DNA polymerase III subunit alpha conserved
SMc03789 -2.2 -3.2 hypothetical protein conserved
SMc02510 -2.1 -0.9 ferric uptake regulation protein compare
SMc02856 -2.1 -8.6 penicillin-binding protein compare
SMa2253 -2.1 -1.4 hypothetical protein compare
SMc02495 -2.1 -0.9 translaldolase compare
SMc03128 -2.1 -3.1 ABC transporter permease compare
SM_b20655 -2.1 -2.4 hypothetical protein compare
SMc01183 -2.0 -1.3 LexA repressor compare
SMc01361 -2.0 -5.8 dihydroorotase compare
SMc02576 -2.0 -1.3 acetyltransferase compare
SMc00791 -2.0 -1.5 hypothetical protein compare
SMc00876 -1.9 -3.8 ATP-binding MRP protein compare
SMc00461 -1.9 -1.6 deoxyuridine 5'-triphosphate nucleotidohydrolase compare
SM_b20105 -1.9 -1.8 transcriptional regulator compare
SMc03878 -1.9 -1.9 acetoacetyl-CoA reductase compare
SMc02484 -1.9 -2.9 amino acid efflux transmembrane protein compare
SMc00378 -1.9 -2.7 exodeoxyribonuclease VII large subunit compare
SMc03790 -1.9 -3.6 hypothetical protein compare
SMc00228 -1.9 -7.8 ATP-dependent DNA helicase RecG conserved
SMc00450 -1.9 -1.9 protoheme IX farnesyltransferase compare
SMa1118 -1.8 -1.5 HspC2 heat shock protein compare
SMc02868 -1.8 -3.1 multidrug efflux system protein compare
SMc01315 -1.8 -1.3 hypothetical protein compare
SMa2289 -1.7 -1.2 hypothetical protein compare
SMc04085 -1.7 -3.9 hypothetical protein compare
SMc00191 -1.7 -1.3 hypothetical protein compare
SMc00689 -1.7 -4.8 lipoprotein compare
SMc02149 -1.7 -1.7 hypothetical protein compare
SMc00012 -1.7 -1.1 cytochrome C oxidase assembly protein compare
SMc00982 -1.6 -4.1 dioxygenase compare
SMc02234 -1.6 -2.1 hypothetical protein compare
SMc00580 -1.6 -3.2 4-hydroxythreonine-4-phosphate dehydrogenase compare
SM_b21173 -1.6 -1.6 hypothetical protein compare
SMc00914 -1.6 -3.0 oxidoreductase compare
SMc01569 -1.6 -0.9 carbamoyl phosphate synthase small subunit compare
SMc03773 -1.6 -3.6 hypothetical protein compare
SMc04224 -1.5 -1.0 hypothetical protein compare
SMc00987 -1.5 -1.7 hypothetical protein compare
SM_b21443 -1.5 -1.8 hypothetical protein compare
SMc03746 -1.5 -1.7 hypothetical protein compare
SMc00166 -1.5 -1.3 oxidoreductase NAD protein compare
SMa0992 -1.5 -2.9 hypothetical protein compare
SMc02739 -1.5 -2.7 glycine betaine transport ATP-binding ABC transporter protein compare
SM_b20387 -1.5 -1.6 transcriptional regulator compare
SMc02143 -1.5 -2.5 phosphate ABC transporter permease compare
SMc00451 -1.5 -3.9 processing protease compare
SMc01145 -1.4 -1.9 hypothetical protein compare
SMc02544 -1.4 -0.8 hypothetical protein compare
SMc01724 -1.4 -2.3 hypothetical protein compare
SMc02071 -1.4 -3.1 hydrolase glycosidase compare
SMc00588 -1.4 -1.4 L-arabinose 1-dehydrogenase; D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48) (from data) compare
SM_b20114 -1.4 -2.4 hypothetical protein compare
SMc01215 -1.4 -2.3 carbamoyl phosphate synthase large subunit compare
SMc01337 -1.4 -1.2 hypothetical protein compare
SMa2095 -1.4 -3.1 hypothetical protein compare
SMc02719 -1.4 -0.9 transposase compare
SMc01007 -1.4 -0.8 hypothetical protein compare
SMc02114 -1.4 -2.2 hypothetical protein compare
SMc01700 -1.4 -3.7 peptidyl-prolyl cis-trans isomerase A compare
SMc01438 -1.3 -3.3 protease precursor signal peptide protein compare
SMc05011 -1.3 -1.9 bacteriophage DNA-binding transcription regulator compare
SMa5033 -1.3 -0.8 hypothetical protein compare
SMc01881 -1.3 -1.5 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SMc03100 -1.3 -1.0 hypothetical protein compare
SMc01457 -1.3 -6.0 transport transmembrane protein compare
SMc03795 -1.3 -1.1 isopropylmalate isomerase small subunit compare
SMc01427 -1.3 -1.0 hypothetical protein compare
SM_b20075 -1.2 -1.6 hypothetical protein compare
SM_b21347 -1.2 -1.4 pectin degradation protein compare
SMa1809 -1.2 -2.8 Non-heme haloperoxidase compare
SMa1233 -1.2 -1.5 NapB periplasmic nitrate reductase cytochrome c- type subunit compare
SMc01641 -1.2 -1.2 carnitinyl-CoA dehydratase compare
SMa1924 -1.2 -0.7 hypothetical protein compare
SM_b21501 -1.2 -1.5 hypothetical protein compare
SMc00425 -1.2 -1.5 transcriptional regulator compare
SM_b20687 -1.2 -3.5 hypothetical protein compare
SMc01424 -1.2 -2.3 nitrile hydratase subunit alpha protein compare
SMc00404 -1.2 -0.7 hypothetical protein compare
SMc02833 -1.2 -1.5 penicillin-insensitive murein endopeptidase compare
SMc01929 -1.2 -2.1 hypothetical protein compare
SM_b20711 -1.2 -1.6 hypothetical protein compare
SMc01280 -1.2 -1.4 protease compare
SMa1239 -1.2 -1.5 NapD component of periplasmic nitrate reductase compare
SMc00286 -1.2 -1.2 hemolysin-type calcium-binding protein compare
SMc01419 -1.2 -1.2 RNA polymerase sigma factor protein compare
SMc02141 -1.2 -1.7 phosphate transporter PhoU compare
SMc00296 -1.2 -4.8 POLY3-hydroxybutyrate polymerase compare
SMc04242 -1.2 -1.0 zinc uptake regulation protein compare
SMa1398 -1.2 -2.1 3-ketoacyl-ACP reductase compare
SMc00067 -1.2 -6.1 outer-membranne lipoprotein compare
SMc03182 -1.2 -2.7 pH adaptation potassium efflux system E transmembrane protein compare
SMc00540 -1.2 -2.0 hypothetical protein compare
SMc00466 -1.1 -2.6 hypothetical protein compare
SMc02227 -1.1 -2.8 fatty oxidation complex enoyl-COA hydratase/3-hydroxyacyl-COA dehydrogenase/3-hydroxybutyryl-COA epimerase compare
SMc02485 -1.1 -0.9 signal peptide protein compare
SM_b21400 -1.1 -1.1 hypothetical protein compare
SMc01360 -1.1 -1.9 aspartate carbamoyltransferase catalytic subunit compare
SMc01036 -1.1 -1.7 hypothetical protein compare
SMc02564 -1.1 -1.6 LysM domain/BON superfamily protein compare
SMc00369 -1.1 -0.9 oxidoreductase compare
SMc03850 -1.1 -0.9 heme exporter D (cytochrome C-type biogenesis protein) transmembrane compare
SMc02309 -1.1 -3.1 arsenate reductase compare
SM_b21100 -1.1 -1.9 polysaccharide deacetylase compare
SMc01220 -1.1 -3.2 lipopolysaccharide core biosynthesis glycosyl transferase compare
SMc02619 -1.1 -3.2 hypothetical protein compare
SMc00823 -1.1 -1.3 hypothetical protein compare
SM_b21539 -1.1 -3.7 aldehyde dehydrogenase compare
SMc01204 -1.1 -3.9 transmembrane oxidoreductase compare
SMc02362 -1.1 -1.8 cytochrome c-type biogenesis protein CcmE compare
SMc00726 -1.1 -0.7 thiol:disulfide interchange redox-active center transmembrane protein compare
SM_b20837 -1.1 -1.6 hypothetical protein compare
SM_b21373 -1.1 -2.7 D-tagatose 6-phosphate 4-epimerase [EC:5.1.3.40] (from data) compare
SMc01723 -1.1 -1.2 hypothetical protein compare
SMc03129 -1.1 -3.8 hypothetical protein compare
SMa1002 -1.1 -1.0 hypothetical protein compare
SMc01789 -1.1 -3.3 signal peptide protein compare
SMa0232 -1.1 -2.3 hypothetical protein compare
SM_b20880 -1.0 -4.3 ATP-dependent RNA helicase compare
SMa1151 -1.0 -3.2 hypothetical protein compare
SMc04200 -1.0 -2.1 signal peptide protein compare
SM_b20822 -1.0 -3.6 cell surface polysaccharide export ABC-2 transporter permease, close relative to wzm1Y20833 compare
SMa0887 -1.0 -2.5 hypothetical protein compare
SMc00419 -1.0 -3.1 glutathione synthetase compare
SMa0144 -1.0 -0.6 hypothetical protein compare
SMc01259 -1.0 -1.6 hypothetical protein compare
SMa2215 -1.0 -2.6 GntR family transcriptional regulator compare
SMc03180 -1.0 -2.8 monovalent cation/H+ antiporter subunit C compare
SM_b21003 -1.0 -1.2 oxidoreductase compare
SM_b21489 -1.0 -2.0 cytochrome O ubiquinol oxidase subunit III compare
SMc01187 -1.0 -1.2 rare lipoprotein A compare
SMc03183 -1.0 -2.4 monovalent cation/H+ antiporter subunit F compare
SMc02084 -1.0 -0.6 biopolymer transport transmembrane protein compare
SM_b20563 -1.0 -1.5 hypothetical protein compare
SM_b20119 -1.0 -1.6 hypothetical protein compare
SMa0922 -1.0 -2.4 hypothetical protein compare
SMc00410 -1.0 -2.6 oxidoreductase compare
SM_b21132 -1.0 -2.5 sulfate ABC transporter permease compare
SMa1765 -0.9 -0.8 hypothetical protein compare
SMc05020 -0.9 -0.9 entericidin A precursor compare
SMa1570 -0.9 -0.8 PilA2 pilus assembly protein compare
SM_b20450 -0.9 -4.7 regulatory protein compare
SM_b20400 -0.9 -1.7 hypothetical protein compare
SMc00917 -0.9 -1.8 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
SMc01242 -0.9 -1.5 signal peptide protein compare


Specific Phenotypes

For 6 genes in this experiment

For stress Cisplatin in Sinorhizobium meliloti 1021

For stress Cisplatin across organisms