Experiment set3IT042 for Sinorhizobium meliloti 1021

Compare to:

LB with Cisplatin 0.0005 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
SMc02112 +3.5 17.1 hypothetical protein compare
SMc04003 +2.9 7.2 50S ribosomal protein L36 compare
SMc00150 +2.9 25.4 hypothetical protein compare
SMc03900 +2.8 20.5 cyclic beta-1,2-glucan ABc transporter compare
SMc04382 +2.8 24.4 beta-(1,2)-glucan production associated transmembrane protein compare
SMc00647 +2.8 9.7 ribosomal large subunit pseudouridine synthase compare
SMc04094 +2.8 5.8 hypothetical protein compare
SMc04454 +2.7 12.2 ABC transporter ATP-binding protein compare
SMc02365 +2.6 11.9 protease precursor protein compare
SMc03069 +2.6 6.8 6-phosphogluconolactonase compare
SMc02640 +2.5 7.7 UDP-glucuronic acid epimerase compare
SMc02367 +2.5 13.3 sensor histidine kinase transmembrane protein compare
SMc02366 +2.5 15.5 transcriptional regulator compare
SMc00349 +2.4 15.0 GTP-binding protein LepA compare
SMc02659 +2.4 7.9 GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase) protein compare
SMc01099 +2.3 5.6 tRNA pseudouridine synthase A compare
SMc02713 +2.3 3.1 RNA polymerase sigma-E factor (sigma-24) protein compare
SMc02137 +2.2 8.5 ornithine carbamoyltransferase compare
SMc00495 +2.2 8.0 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc03826 +2.2 3.0 argininosuccinate synthase compare
SMc00458 +2.1 14.5 transcriptional regulator compare
SMc02695 +2.0 9.3 GTP-dependent nucleic acid-binding protein EngD compare
SMc03855 +2.0 4.7 hypothetical protein compare
SMc01858 +2.0 2.0 S-adenosyl-methyltransferase MraW compare
SMc02058 +1.9 5.2 YAJC protein compare
SMc03863 +1.9 5.1 50S ribosomal protein L19 compare
SMc00496 +1.9 2.1 hypothetical protein compare
SMc00070 +1.9 4.8 signal peptide protein compare
SMc00403 +1.9 8.1 NOL1/NOP2/SUN family signature protein compare
SMc02246 +1.8 1.4 hypothetical protein compare
SMc00622 +1.8 9.6 ribonuclease D protein compare
SMc00761 +1.8 12.2 oxidoreductase compare
SMc00482 +1.8 6.3 hypothetical protein compare
SMc02434 +1.8 5.1 hypothetical protein compare
SM_b20616 +1.8 2.1 thiamine biosynthesis oxidoreductase compare
SMc01842 +1.7 3.9 methyltransferase transcription regulator protein compare
SMc02714 +1.7 2.6 hypothetical protein compare
SMc00131 +1.7 10.2 transcriptional regulator compare
SMc00129 +1.6 5.9 sensor histidine kinase compare
SMc01907 +1.6 11.5 hypothetical protein compare
SMc02901 +1.6 1.3 hypothetical protein compare
SMc00320 +1.5 5.7 ribosome-binding factor A compare
SMc02497 +1.5 2.9 hypothetical protein compare
SMc04235 +1.5 4.9 tRNA-dihydrouridine synthase A compare
SMc04001 +1.5 1.6 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc00522 +1.4 8.1 ATP-dependent RNA helicase compare
SMc03931 +1.4 9.7 sarcosine oxidase subunit alpha compare
SMc00998 +1.4 7.8 signal peptide protein compare
SMc00143 +1.4 2.0 molybdopterin-guanine dinucleotide biosynthesis protein MobA compare
SMc04000 +1.3 2.0 hypothetical protein compare
SMc03933 +1.3 9.8 sarcosine oxidase subunit B protein compare
SM_b20226 +1.3 1.2 hypothetical protein compare
SMc00187 +1.3 2.1 ubiquinol-cytochrome C reductase iron-sulfur subunit protein compare
SM_b21253 +1.2 4.7 hypothetical protein compare
SMc01124 +1.2 6.4 PII uridylyl-transferase compare
SM_b21084 +1.2 2.7 hypothetical protein compare
SMc01698 +1.2 5.9 oxidoreductase compare
SMc03930 +1.2 1.7 sarcosine oxidase subunit gamma compare
SM_b20613 +1.2 5.8 C4-dicarboxylate transport transcriptional regulator compare
SM_b21170 +1.2 3.0 guanylate kinase compare
SMc03836 +1.2 1.5 acyl-CoA thioesterase i protein compare
SMc00684 +1.2 3.0 hypothetical protein compare
SMc00325 +1.2 6.5 hypothetical protein compare
SMc03111 +1.2 4.7 mannose 6-phosphate isomerase (EC 5.3.1.8) (from data) compare
SM_b20086 +1.2 1.0 hypothetical protein compare
SMc02269 +1.1 5.4 capsular polysaccharide biosynthesis/export protein compare
SMc01275 +1.1 4.9 ribosomal large subunit pseudouridine synthase C protein compare
SMc03880 +1.1 5.0 hypothetical protein compare
SMc00976 +1.1 1.1 enoyl-CoA hydratase compare
SMa1400 +1.1 2.3 acyl-CoA dehydrogenase compare
SMc00618 +1.1 6.7 polyphosphate kinase compare
SMc02138 +1.1 3.9 acetylornithine transaminase compare
SMa1625 +1.1 1.2 LysR family transcriptional regulator compare
SMc03961 +1.1 4.2 sulfolipid (UDP-sulfoquinovose) biosynthesis protein compare
SMc01439 +1.1 3.0 hypothetical protein compare
SMc00329 +1.1 1.9 iron response regulator protein compare
SMc00650 +1.1 1.6 hypothetical protein compare
SMa1658 +1.1 1.8 hypothetical protein compare
SMc00176 +1.0 3.0 hypothetical protein compare
SMc01613 +1.0 2.3 ribose-5-phosphate isomerase B compare
SMc02854 +1.0 5.8 signal peptide protein compare
SMc00727 +1.0 4.7 3-hydroxybutyryl-CoA dehydrogenase compare
SMc02765 +1.0 5.9 tryptophan synthase subunit alpha compare
SMc00877 +1.0 6.1 transcriptional regulator compare
SMa1639 +1.0 1.0 hypothetical protein compare
SMa2020 +1.0 3.3 Transcriptional regulator compare
SMc01139 +1.0 4.5 RNA polymerase factor sigma-54 compare
SMc01041 +1.0 2.3 NIFR3-like protein compare
SMc02385 +1.0 2.5 hypothetical protein compare
SM_b20540 +1.0 1.0 hypothetical protein compare
SMc01116 +1.0 3.7 acyltransferase transmembrane protein compare
SM_b21397 +1.0 0.9 hypothetical protein compare
SMc02757 +1.0 2.5 hypothetical protein compare
SMc01107 +1.0 4.9 hypothetical protein compare
SMc02136 +1.0 3.0 Hsp33-like chaperonin compare
SM_b20897 +1.0 1.2 hypothetical protein compare
SMc02449 +0.9 1.9 acetyltransferase compare
SMc02565 +0.9 3.8 hypothetical protein compare
SM_b20427 +0.9 1.3 amino acid ABC transporter ATP-binding protein compare
SMc00711 +0.9 2.8 cyclohexadienyl dehydrogenase compare
SMc02858 +0.9 0.4 chaperone protein DnaJ compare
SMc02826 +0.9 1.6 transcriptional regulator compare
SM_b20819 +0.9 2.5 ferredoxin compare
SMc04002 +0.9 2.8 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SM_b20549 +0.9 3.0 hypothetical protein compare
SM_b21452 +0.9 2.1 hypothetical protein compare
SMc00169 +0.9 6.5 malic enzyme compare
SMc00455 +0.9 2.2 hypothetical protein compare
SMc02273 +0.9 7.3 fatty acid synthase transmembrane protein compare
SMc00494 +0.9 1.1 phosphoribosylformylglycinamidine synthase subunit PurS compare
SMa1921 +0.9 1.1 hypothetical protein compare
SMc04428 +0.9 1.7 hypothetical protein compare
SMc02272 +0.9 4.5 acyl-transferase transferase compare
SM_b20081 +0.9 1.6 hypothetical protein compare
SMc01223 +0.9 1.5 transcriptional regulator compare
SM_b21491 +0.9 5.6 hypothetical protein compare
SMc02766 +0.9 5.2 tryptophan synthase subunit beta compare
SMc01801 +0.9 1.8 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SMc01440 +0.9 3.9 hydrolase serine protease transmembrane protein compare
SMa1430 +0.9 2.2 Dehydrogenase, Zn-dependent compare
SMc02384 +0.9 3.9 glycosyltransferase transmembrane protein compare
SMc02864 +0.9 1.5 molybdopterin biosynthesis protein MoeB compare
SMc01957 +0.9 2.0 hypothetical protein compare
SMc02524 +0.9 3.0 formate dehydrogenase subunit gamma compare
SM_b20684 +0.9 5.7 hypothetical protein compare
SM_b21374 +0.9 1.4 tagatose kinase (EC 2.7.1.101) (from data) compare
SMc02166 +0.9 4.1 dihydroorotase compare
SMc01660 +0.8 1.8 hypothetical protein compare
SMc00904 +0.8 3.0 hypothetical protein compare
SMc01930 +0.8 1.5 hypothetical protein compare
SMc00093 +0.8 5.2 choline dehydrogenase compare
SMc01939 +0.8 1.0 urease subunit beta compare
SMc01769 +0.8 5.9 hypothetical protein compare
SMc01089 +0.8 0.9 hypothetical protein compare
SMa0667 +0.8 1.4 hypothetical protein compare
SMc01131 +0.8 2.1 hypothetical protein compare
SMc05017 +0.8 3.4 transposase compare
SMc04319 +0.8 1.5 hypothetical protein compare
SMc01222 +0.8 3.2 lipopolysaccharide core biosynthesis glycosyl transferase compare
SMc04441 +0.8 1.2 hypothetical protein compare
SMa0448 +0.8 1.5 hypothetical protein compare
SMc02490 +0.8 2.8 hypothetical protein compare
SMa5018 +0.8 1.2 hypothetical protein compare
SMc03963 +0.8 3.0 sulfolipid biosynthesis protein compare
SMc04343 +0.8 3.8 adenylate/guanylate cyclase transmembrane protein compare
SMc01112 +0.8 3.3 hypothetical protein compare
SMc01852 +0.8 3.8 pyrophosphate--fructose-6-phosphate 1-phosphotransferase compare
SMc03999 +0.8 1.3 hypothetical protein compare
SMa0450 +0.8 1.3 hypothetical protein compare
SM_b21441 +0.8 1.5 inosine-5'-monophosphate dehydrogenase compare
SMc02975 +0.8 3.0 phosphoenolpyruvate carboxykinase regulator transcription regulator protein compare
SM_b21377 +0.8 1.9 sugar uptake ABC transporter substrate-binding protein precursor compare
SMc01256 +0.8 3.7 L-serine dehydratase compare
SMc00788 +0.8 2.7 peptide ABC transporter permease compare
SMc02275 +0.7 1.8 pyrazinamidase/nicotinamidase (Includes: pyrazinamidase, nicotinamidase) protein compare
SMc04130 +0.7 2.8 hypothetical protein compare
SMc03250 +0.7 1.9 hypothetical protein compare
SMc00505 +0.7 1.0 hypothetical protein compare
SMc00648 +0.7 1.9 hypothetical protein compare
SMc00061 +0.7 1.9 hypothetical protein compare
SM_b20385 +0.7 1.6 hypothetical protein compare
SM_b20953 +0.7 0.8 hypothetical protein compare
SMc01026 +0.7 1.7 hypothetical protein compare
SMc01508 +0.7 1.0 hypothetical protein compare
SMc02383 +0.7 4.5 hypothetical protein compare
SM_b21024 +0.7 2.4 hypothetical protein compare
SMc02247 +0.7 0.7 signal peptide protein compare
SMc00321 +0.7 2.7 tRNA pseudouridine synthase B compare
SMc01193 +0.7 4.2 hypothetical protein compare
SMc04213 +0.7 1.2 diacylglycerol kinase compare
SMc00075 +0.7 3.3 ribosomal-protein-alanine acetyltransferase compare
SMa1956 +0.7 2.1 hypothetical protein compare
SMc01009 +0.7 2.5 hypothetical protein compare
SM_b21569 +0.7 1.1 transcriptional regulator compare
SM_b21256 +0.7 4.1 nucleotide sugar oxidase compare
SMc01214 +0.7 2.4 zinc-containing alcohol dehydrogenase compare
SMc04233 +0.7 1.2 hypothetical protein compare
SMc00712 +0.7 0.6 hypothetical protein compare
SMc01651 +0.7 1.2 transcriptional regulator compare
SMc02287 +0.7 2.2 DNA-invertase compare
SMc04352 +0.7 3.6 signal peptide protein compare
SMc00094 +0.7 4.7 betaine aldehyde dehydrogenase compare
SM_b20691 +0.7 1.1 hypothetical protein compare
SMc04125 +0.7 2.1 ABC transporter permease compare
SMa0833 +0.7 0.9 hypothetical protein compare
SMc03996 +0.7 1.7 thiamine-phosphate pyrophosphorylase compare
SMc02658 +0.7 1.2 hypothetical protein compare
SMc01953 +0.7 3.1 2-component receiver domain-containing protein compare
SMc00945 +0.7 2.1 xanthine-guanine phosphoribosyltransferase compare
SMc00554 +0.7 2.4 amidophosphoribosyltransferase compare
SMa1367 +0.7 0.7 short chain alcohol dehydrogenase-related dehydrogenase compare
SMc01001 +0.7 3.4 hypothetical protein compare
SM_b20055 +0.7 1.2 transcriptional regulator compare
SM_b21265 +0.7 3.2 glycosyltransferase compare
SMc03943 +0.7 1.6 hypothetical protein compare
SMc00340 +0.7 2.0 oxidoreductase compare
SMc02407 +0.7 2.4 hypothetical protein compare
SMc02095 +0.7 2.7 hypothetical protein compare
SMc02812 +0.7 0.7 hypothetical protein compare
SM_b20751 +0.7 1.3 3-hydroxyisobutyrate dehydrogenase compare


Specific Phenotypes

For 6 genes in this experiment

For stress Cisplatin in Sinorhizobium meliloti 1021

For stress Cisplatin across organisms