Experiment set3IT042 for Methanococcus maripaludis S2

200 most detrimental genes:

gene	name	fitness	t score	description
MMP_RS01650		+1.1	2.1	sulfurtransferase TusA family protein
MMP_RS02470		+1.1	1.5	helix-turn-helix transcriptional regulator
MMP_RS03340		+0.6	1.2	ABC transporter ATP-binding protein
MMP_RS00675		+0.6	1.2	nitroreductase family protein
MMP_RS01075		+0.6	0.9	hypothetical protein
MMP_RS07120		+0.5	4.5	coenzyme F420 hydrogenase subunit alpha
MMP_RS08310		+0.5	2.2	TMEM165/GDT1 family protein
MMP_RS02605		+0.5	0.8	MotA/TolQ/ExbB proton channel family protein
MMP_RS01435		+0.5	2.5	DMT family transporter
MMP_RS07130		+0.5	3.7	coenzyme F420 hydrogenase subunit gamma
MMP_RS07895		+0.5	2.0	cytochrome c
MMP_RS09035		+0.4	1.4	hypothetical protein
MMP_RS00545		+0.4	2.9	XRE family transcriptional regulator
MMP_RS02175		+0.4	0.6	DUF1611 domain-containing protein
MMP_RS06975		+0.4	1.5	sulfide-dependent adenosine diphosphate thiazole synthase
MMP_RS07345		+0.4	2.3	glycine synthesis protein GlyXL (from data)
MMP_RS02410		+0.4	1.3	ABC transporter substrate-binding protein
MMP_RS08380		+0.4	2.0	phosphatase PAP2 family protein
MMP_RS08775		+0.4	2.2	methanogenesis marker 9 domain-containing protein
MMP_RS08500		+0.4	2.6	pyridoxal 5'-phosphate synthase glutaminase subunit PdxT
MMP_RS03890		+0.3	1.8	DUF2540 domain-containing protein
MMP_RS05970		+0.3	1.7	class II SORL domain-containing protein
MMP_RS08455		+0.3	2.1	multiprotein bridging factor aMBF1
MMP_RS07850		+0.3	1.4	prephenate dehydratase
MMP_RS06005		+0.3	2.2	heavy-metal-associated domain-containing protein
MMP_RS08260		+0.3	1.9	DUF99 family protein
MMP_RS04740		+0.3	2.1	DUF473 domain-containing protein
MMP_RS07835		+0.3	1.3	TldD/PmbA family protein
MMP_RS07135		+0.3	2.2	coenzyme F420 hydrogenase subunit beta
MMP_RS01960		+0.3	0.4	hypothetical protein
MMP_RS09025		+0.3	0.8	hypothetical protein
MMP_RS01855		+0.3	2.1	2-hydroxyacyl-CoA dehydratase family protein
MMP_RS05675		+0.3	1.6	phosphate ABC transporter ATP-binding protein PstB
MMP_RS01080		+0.3	1.5	DUF2202 domain-containing protein
MMP_RS06610		+0.3	1.5	DUF2334 domain-containing protein
MMP_RS08485		+0.3	2.2	tungstate ABC transporter substrate-binding protein WtpA
MMP_RS03465		+0.3	0.7	adenine phosphoribosyltransferase
MMP_RS07900		+0.3	0.7	YeeE/YedE family protein
MMP_RS06540		+0.3	1.5	3-methyl-2-oxobutanoate dehydrogenase subunit VorB
MMP_RS02675		+0.3	1.2	hypothetical protein
MMP_RS07125		+0.3	1.7	coenzyme F420-reducing hydrogenase FrhD protein
MMP_RS08275		+0.3	2.3	hypothetical protein
MMP_RS05835		+0.3	0.5	secondary thiamine-phosphate synthase enzyme YjbQ
MMP_RS08400		+0.3	1.2	MJ0307 family thioredoxin
MMP_RS05975		+0.3	0.8	hypothetical protein
MMP_RS00655		+0.3	1.4	hypothetical protein
MMP_RS07970		+0.3	1.2	hypothetical protein
MMP_RS02745		+0.3	1.0	hypothetical protein
MMP_RS07560		+0.3	1.6	prefoldin subunit alpha
MMP_RS04050		+0.3	1.4	hypothetical protein
MMP_RS08610		+0.3	2.0	flagellar protein F
MMP_RS05695		+0.3	2.0	phospholipase D-like domain-containing protein
MMP_RS00955		+0.2	1.9	coenzyme gamma-F420-2:alpha-L-glutamate ligase
MMP_RS06910		+0.2	2.0	RlmF-related methyltransferase
MMP_RS04205		+0.2	1.5	carboxymuconolactone decarboxylase family protein
MMP_RS00395		+0.2	0.8	MGMT family protein
MMP_RS05985		+0.2	1.0	hypothetical protein
MMP_RS07155		+0.2	2.0	MFS transporter
MMP_RS06655		+0.2	1.8	glycoside hydrolase family 15 protein
MMP_RS08835		+0.2	1.6	H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein
MMP_RS06905		+0.2	1.0	hypothetical protein
MMP_RS07620		+0.2	0.7	energy-coupling factor ABC transporter substrate-binding protein
MMP_RS01370		+0.2	2.0	acetate--CoA ligase family protein
MMP_RS01635		+0.2	1.2	thiamine pyrophosphate-dependent enzyme
MMP_RS05275		+0.2	1.9	AI-2E family transporter
MMP_RS07100		+0.2	1.9	hypothetical protein
MMP_RS06325		+0.2	0.7	hypothetical protein
MMP_RS09050		+0.2	1.5	CAP domain-containing protein
MMP_RS05790		+0.2	1.4	HDIG domain-containing protein
MMP_RS06665		+0.2	1.8	glycogen/starch synthase
MMP_RS06930		+0.2	1.5	MBL fold metallo-hydrolase
MMP_RS01975		+0.2	1.9	hypothetical protein
MMP_RS08390		+0.2	1.7	DUF5400 domain-containing protein
MMP_RS01685		+0.2	1.1	indolepyruvate oxidoreductase subunit beta
MMP_RS02705		+0.2	1.5	formylmethanofuran dehydrogenase subunit B
MMP_RS03790		+0.2	1.6	hypothetical protein
MMP_RS08205		+0.2	1.6	stage II sporulation protein M
MMP_RS08620		+0.2	1.3	flagellar accessory protein FlaH
MMP_RS08670		+0.2	1.4	metallophosphoesterase
MMP_RS02045		+0.2	0.6	tRNA-Met
MMP_RS01945		+0.2	1.2	DUF4350 domain-containing protein
MMP_RS08580		+0.2	1.3	flagellin
MMP_RS02540		+0.2	1.1	DUF2283 domain-containing protein
MMP_RS09030		+0.2	1.1	hypothetical protein
MMP_RS01970		+0.2	1.5	TIGR04279 domain-containing protein
MMP_RS08090		+0.2	0.8	hypothetical protein
MMP_RS07150		+0.2	1.1	MTH895/ArsE family thioredoxin-like protein
MMP_RS02770		+0.2	1.3	hypothetical protein
MMP_RS06490		+0.2	1.1	hypothetical protein
MMP_RS08980		+0.2	1.3	hypothetical protein
MMP_RS06875		+0.2	1.2	FAD-dependent oxidoreductase
MMP_RS06495		+0.2	1.0	YkgJ family cysteine cluster protein
MMP_RS00665		+0.2	0.8	hypothetical protein
MMP_RS02680		+0.2	0.9	ABC transporter permease
MMP_RS07890		+0.2	0.5	OB-fold nucleic acid binding domain-containing protein
MMP_RS05945		+0.2	1.3	CBS domain-containing protein
MMP_RS03520		+0.2	0.8	YwbE family protein
MMP_RS07925		+0.2	1.3	haloacid dehalogenase
MMP_RS01130		+0.2	1.4	flavoprotein
MMP_RS06710		+0.2	1.1	selenium-binding protein
MMP_RS07805		+0.2	1.4	ABC transporter permease
MMP_RS02960		+0.2	1.3	class I SAM-dependent methyltransferase family protein
MMP_RS08280		+0.2	0.8	proteasome assembly chaperone family protein
MMP_RS00085		+0.2	1.5	DNA cytosine methyltransferase
MMP_RS06560		+0.2	1.4	hypothetical protein
MMP_RS01630		+0.2	1.3	N-glycosylase/DNA lyase
MMP_RS07590		+0.2	1.5	hypothetical protein
MMP_RS02445		+0.2	1.5	putative DNA binding domain-containing protein
MMP_RS06190		+0.2	1.5	tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO
MMP_RS01060		+0.2	1.5	calcium/sodium antiporter
MMP_RS00540		+0.2	1.2	PLP-dependent aminotransferase family protein
MMP_RS07840		+0.2	0.9	ribonuclease III
MMP_RS08470		+0.2	1.3	ATP-binding cassette domain-containing protein
MMP_RS06070		+0.2	1.4	iron ABC transporter substrate-binding protein
MMP_RS08575		+0.2	1.5	hypothetical protein
MMP_RS06520		+0.2	0.6	DUF1786 domain-containing protein
MMP_RS06155		+0.2	0.8	DUF4186 domain-containing protein
MMP_RS07770		+0.2	1.1	alanine racemase
MMP_RS07145		+0.2	1.2	AmmeMemoRadiSam system protein B
MMP_RS05140		+0.2	0.8	helix-turn-helix transcriptional regulator
MMP_RS09065		+0.2	1.4	hypothetical protein
MMP_RS04270		+0.2	1.2	coenzyme F420 hydrogenase subunit alpha
MMP_RS01785		+0.2	1.0	hypothetical protein
MMP_RS08235		+0.2	1.0	hypothetical protein
MMP_RS06735		+0.2	1.0	class I SAM-dependent rRNA methyltransferase
MMP_RS00940		+0.2	1.3	daunorubicin resistance protein DrrA family ABC transporter ATP-binding protein
MMP_RS06045		+0.2	1.2	DNA polymerase
MMP_RS03765		+0.2	0.9	CopG family ribbon-helix-helix protein
MMP_RS08405		+0.2	1.3	MFS transporter
MMP_RS03350		+0.2	1.0	winged helix-turn-helix domain-containing protein
MMP_RS08315		+0.2	0.8	S-methyl-5-thioribose-1-phosphate isomerase
MMP_RS03965		+0.2	0.6	hypothetical protein
MMP_RS00635		+0.1	1.1	energy-coupling factor transporter transmembrane protein EcfT
MMP_RS06965		+0.1	1.0	TIGR04014 family B12-binding domain/radical SAM domain-containing protein
MMP_RS01980		+0.1	1.3	trimeric intracellular cation channel family protein
MMP_RS02490		+0.1	0.8	hypothetical protein
MMP_RS00535		+0.1	0.6	TIGR00375 family protein
MMP_RS03745		+0.1	1.1	phenylacetate--CoA ligase
MMP_RS08285		+0.1	1.1	serine/threonine protein kinase
MMP_RS00530		+0.1	0.8	tRNA pseudouridine(54/55) synthase Pus10
MMP_RS05900		+0.1	1.2	tetratricopeptide repeat protein
MMP_RS07185		+0.1	1.2	pyridoxal phosphate-dependent aminotransferase
MMP_RS05355		+0.1	0.2	hypothetical protein
MMP_RS03990		+0.1	1.0	recombinase family protein
MMP_RS05940		+0.1	1.0	corrinoid protein
MMP_RS02405		+0.1	0.6	hypothetical protein
MMP_RS06320		+0.1	0.9	hypothetical protein
MMP_RS01675		+0.1	0.5	hypothetical protein
MMP_RS04030		+0.1	1.1	hypothetical protein
MMP_RS05960		+0.1	1.1	CoB--CoM heterodisulfide reductase subunit B
MMP_RS06335		+0.1	0.9	HAD family hydrolase
MMP_RS02455		+0.1	1.0	hypothetical protein
MMP_RS08385		+0.1	0.8	ABC transporter substrate-binding protein
MMP_RS07715		+0.1	1.0	YfcE family phosphodiesterase
MMP_RS08325		+0.1	1.1	hypothetical protein
MMP_RS01430		+0.1	1.0	mechanosensitive ion channel family protein
MMP_RS06435		+0.1	0.8	CBS domain-containing protein
MMP_RS07650		+0.1	1.1	TldD/PmbA family protein
MMP_RS01065		+0.1	1.2	alpha/beta hydrolase
MMP_RS03900		+0.1	0.9	minichromosome maintenance protein MCM
MMP_RS01260		+0.1	0.8	HDIG domain-containing protein
MMP_RS01965		+0.1	0.7	DUF1616 domain-containing protein
MMP_RS08615		+0.1	0.4	flagellar protein G
MMP_RS06365		+0.1	0.6	hypothetical protein
MMP_RS08480		+0.1	1.1	molybdate ABC transporter substrate-binding protein
MMP_RS05530		+0.1	1.0	signal peptide peptidase SppA
MMP_RS04300		+0.1	0.9	hypothetical protein
MMP_RS07095		+0.1	0.7	PspC domain-containing protein
MMP_RS07910		+0.1	0.8	NAD(P)H-hydrate dehydratase
MMP_RS08850		+0.1	1.1	hypothetical protein
MMP_RS00450		+0.1	0.4	4Fe-4S binding protein
MMP_RS00140		+0.1	1.0	DUF192 domain-containing protein
MMP_RS06570		+0.1	0.6	DUF190 domain-containing protein
MMP_RS08590		+0.1	0.9	flagellin
MMP_RS08640		+0.1	1.1	TIM barrel protein
MMP_RS03730		+0.1	1.0	ABC transporter substrate-binding protein
MMP_RS02845		+0.1	1.1	hypothetical protein
MMP_RS02370		+0.1	0.6	NifB/NifX family molybdenum-iron cluster-binding protein
MMP_RS08700		+0.1	0.9	hypothetical protein
MMP_RS00645		+0.1	0.9	iron ABC transporter permease
MMP_RS07775		+0.1	0.7	alanine dehydrogenase
MMP_RS02315		+0.1	0.9	RimK family alpha-L-glutamate ligase
MMP_RS02905		+0.1	0.5	2-thiouracil desulfurase family protein
MMP_RS01420		+0.1	0.5	hypothetical protein
MMP_RS00905		+0.1	0.7	phenylacetate--CoA ligase
MMP_RS06010		+0.1	1.0	heavy metal translocating P-type ATPase
MMP_RS08630		+0.1	0.7	archaellar assembly protein FlaJ
MMP_RS03820		+0.1	0.9	EamA family transporter
MMP_RS01570		+0.1	0.3	hypothetical protein
MMP_RS05780		+0.1	0.8	multidrug resistance efflux transporter family protein
MMP_RS03830		+0.1	1.0	exodeoxyribonuclease VII large subunit
MMP_RS04445		+0.1	0.6	P-II family nitrogen regulator
MMP_RS05575		+0.1	0.9	hypothetical protein
MMP_RS00945		+0.1	0.3	PadR family transcriptional regulator
MMP_RS00660		+0.1	1.0	alkaline phosphatase family protein
MMP_RS03585		+0.1	0.4	Hsp20/alpha crystallin family protein
MMP_RS04520		+0.1	0.4	nucleoside deaminase
MMP_RS03870		+0.1	0.7	purine NTPase
MMP_RS02585		+0.1	1.0	methyl-accepting chemotaxis protein
MMP_RS02670		+0.1	0.9	ATP-binding cassette domain-containing protein

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in rich t1 experiments