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Experiment set3IT042 for
Methanococcus maripaludis JJ
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formate McAA pyroxidine HCl dropout
200 most important genes:
gene
name
fitness
t score
description
MMJJ
_RS00235
-6.6
-21.6
hypothetical protein
compare
MMJJ
_RS06695
-5.3
-3.6
amidohydrolase
compare
MMJJ
_RS05445
-5.1
-3.3
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
MMJJ
_RS07360
-5.0
-2.8
TIGR00269 family protein
compare
MMJJ
_RS06875
-5.0
-4.8
hypothetical protein
compare
MMJJ
_RS05450
-4.7
-19.0
TIGR03576 family pyridoxal phosphate-dependent enzyme
compare
MMJJ
_RS07705
-4.7
-3.2
GTP-binding protein EngB
compare
MMJJ
_RS01935
-4.7
-5.5
O-phosphoseryl-tRNA(Sec) selenium transferase
compare
MMJJ
_RS04200
-4.7
-8.9
triphosphoribosyl-dephospho-CoA synthase
compare
MMJJ
_RS06860
-4.5
-6.4
hypothetical protein
compare
MMJJ
_RS00215
-4.5
-3.1
CCA tRNA nucleotidyltransferase
compare
MMJJ
_RS04050
-4.4
-3.3
dihydroneopterin aldolase family protein
compare
MMJJ
_RS03760
-4.3
-5.1
hydrogenase maturation nickel metallochaperone HypA
compare
MMJJ
_RS03200
-4.2
-2.9
uroporphyrinogen-III synthase
compare
MMJJ
_RS03840
-4.2
-4.0
DHH family phosphoesterase
compare
MMJJ
_RS01750
-4.2
-4.0
ferrous iron transport protein A
compare
MMJJ
_RS03820
-4.2
-4.9
hydrogenase formation protein HypD
compare
MMJJ
_RS03580
-4.1
-4.9
TIGR00303 family protein
compare
MMJJ
_RS03110
-4.0
-5.4
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase
compare
MMJJ
_RS08250
-4.0
-8.4
hydrogenase maturation peptidase HycI
compare
MMJJ
_RS03270
-4.0
-3.9
ribosome biogenesis/translation initiation ATPase RLI
compare
MMJJ
_RS00275
-4.0
-3.7
coenzyme F420-0:L-glutamate ligase
compare
MMJJ
_RS06255
-4.0
-7.5
tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3
compare
MMJJ
_RS03895
-3.9
-4.4
hydrogenase expression/formation protein HypE
compare
MMJJ
_RS07670
-3.9
-19.0
Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain
compare
MMJJ
_RS05260
-3.9
-8.5
ATP-grasp domain-containing protein
compare
MMJJ
_RS06485
-3.8
-4.5
phosphoglycerate kinase
compare
MMJJ
_RS07665
-3.8
-21.8
formate dehydrogenase subunit alpha
compare
MMJJ
_RS06490
-3.8
-4.5
methanogenesis marker 2 protein
compare
MMJJ
_RS01755
-3.8
-2.6
ferrous iron transport protein B
compare
MMJJ
_RS05535
-3.8
-13.8
hypothetical protein
compare
MMJJ
_RS00270
-3.8
-5.0
adenosylcobinamide-GDP ribazoletransferase
compare
MMJJ
_RS01600
-3.8
-4.4
radical SAM protein
compare
MMJJ
_RS02920
-3.7
-3.7
30S ribosomal protein S27ae
compare
MMJJ
_RS06855
-3.7
-2.9
DUF2104 domain-containing protein
compare
MMJJ
_RS07000
-3.7
-2.8
TrkH family potassium uptake protein
compare
MMJJ
_RS06910
-3.7
-4.3
energy-converting NiFe hydrogenase A subunit EhaA
compare
MMJJ
_RS00450
-3.7
-2.9
DUF126 domain-containing protein
compare
MMJJ
_RS08625
-3.7
-8.1
magnesium/cobalt transporter CorA
compare
MMJJ
_RS03055
-3.7
-3.9
hypothetical protein
compare
MMJJ
_RS03615
-3.7
-4.3
cobalt-precorrin-8 methylmutase
compare
MMJJ
_RS03620
-3.6
-8.0
DUF2097 domain-containing protein
compare
MMJJ
_RS08020
-3.5
-10.0
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS02090
-3.5
-8.3
tyramine--L-glutamate ligase
compare
MMJJ
_RS08320
-3.5
-3.7
CDP-diacylglycerol--serine O-phosphatidyltransferase
compare
MMJJ
_RS05330
-3.5
-3.3
DNA polymerase II large subunit
compare
MMJJ
_RS05930
-3.4
-3.6
cell division protein SepF
compare
MMJJ
_RS07655
-3.4
-15.5
hypothetical protein
compare
MMJJ
_RS07720
-3.3
-3.0
UPF0058 family protein
compare
MMJJ
_RS06725
-3.3
-15.3
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMJJ
_RS05620
-3.3
-5.8
CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein
compare
MMJJ
_RS05650
-3.3
-4.6
formylmethanofuran dehydrogenase subunit B
compare
MMJJ
_RS04685
-3.3
-11.8
carbamoyltransferase HypF
compare
MMJJ
_RS08330
-3.3
-4.5
SufD family Fe-S cluster assembly protein
compare
MMJJ
_RS00560
-3.3
-5.3
homoisocitrate dehydrogenase
compare
MMJJ
_RS03865
-3.2
-2.5
phosphoribosyl-AMP cyclohydrolase
compare
MMJJ
_RS03005
-3.2
-5.2
Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit
compare
MMJJ
_RS03670
-3.2
-6.7
precorrin-2 C(20)-methyltransferase
compare
MMJJ
_RS08005
-3.2
-17.9
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMJJ
_RS08000
-3.2
-11.9
HesA/MoeB/ThiF family protein
compare
MMJJ
_RS06840
-3.2
-5.2
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS04520
-3.1
-7.7
coenzyme F430 synthase
compare
MMJJ
_RS02045
-3.1
-4.5
molybdenum cofactor guanylyltransferase
compare
MMJJ
_RS03125
-3.1
-6.2
GMC oxidoreductase
compare
MMJJ
_RS00210
-3.1
-3.6
DUF530 family protein
compare
MMJJ
_RS06805
-3.1
-4.1
monovalent cation/H+ antiporter subunit E
compare
MMJJ
_RS06915
-3.1
-14.6
helix-turn-helix domain-containing protein
compare
MMJJ
_RS03095
-3.0
-4.0
bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase
compare
MMJJ
_RS01475
-3.0
-3.4
signal recognition particle-docking protein FtsY
compare
MMJJ
_RS03815
-3.0
-3.3
nascent polypeptide-associated complex protein
compare
MMJJ
_RS03785
-3.0
-4.0
hypothetical protein
compare
MMJJ
_RS08055
-3.0
-7.6
methanogenesis marker 14 protein
compare
MMJJ
_RS06375
-3.0
-5.1
UbiX family flavin prenyltransferase
compare
MMJJ
_RS01810
-3.0
-2.6
methyl coenzyme M reductase system, component A2
compare
MMJJ
_RS06180
-2.9
-4.0
tryptophan--tRNA ligase
compare
MMJJ
_RS00355
-2.9
-4.6
ribonuclease P protein component 4
compare
MMJJ
_RS05575
-2.9
-6.4
2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase
compare
MMJJ
_RS05720
-2.9
-3.9
glutamine--fructose-6-phosphate transaminase (isomerizing)
compare
MMJJ
_RS06175
-2.9
-4.0
DUF1743 domain-containing protein
compare
MMJJ
_RS00520
-2.9
-7.4
PDGLE domain-containing protein
compare
MMJJ
_RS01865
-2.9
-6.7
peptidyl-tRNA hydrolase Pth2
compare
MMJJ
_RS05950
-2.9
-4.3
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
compare
MMJJ
_RS06625
-2.9
-3.2
pyruvate synthase subunit PorB
compare
MMJJ
_RS01345
-2.8
-5.4
(5-formylfuran-3-yl)methyl phosphate synthase
compare
MMJJ
_RS00580
-2.8
-2.4
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG
compare
MMJJ
_RS08080
-2.8
-9.8
TIGR00300 family protein
compare
MMJJ
_RS03295
-2.8
-13.3
PHP domain-containing protein
compare
MMJJ
_RS02275
-2.8
-4.6
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS03830
-2.8
-10.6
CBS domain-containing protein
compare
MMJJ
_RS01690
-2.8
-4.7
methanogenesis marker 12 protein
compare
MMJJ
_RS03190
-2.8
-3.7
phosphopyruvate hydratase
compare
MMJJ
_RS03150
-2.8
-8.2
2-phospho-L-lactate transferase
compare
MMJJ
_RS05415
-2.8
-2.6
hypothetical protein
compare
MMJJ
_RS06040
-2.8
-5.7
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS01200
-2.8
-3.6
PRC-barrel domain-containing protein
compare
MMJJ
_RS07380
-2.7
-10.2
sulfide-dependent adenosine diphosphate thiazole synthase
compare
MMJJ
_RS04800
-2.7
-6.6
2-phospho-L-lactate guanylyltransferase
compare
MMJJ
_RS03875
-2.7
-6.2
CBS domain-containing protein
compare
MMJJ
_RS03060
-2.7
-3.9
methanogenesis marker 7 protein
compare
MMJJ
_RS04655
-2.7
-5.7
FAD-dependent oxidoreductase
compare
MMJJ
_RS01565
-2.7
-11.0
TIGR00267 family protein
compare
MMJJ
_RS08855
-2.7
-6.0
cyclic pyranopterin monophosphate synthase MoaC
compare
MMJJ
_RS08535
-2.7
-4.6
NOL1/NOP2/sun family putative RNA methylase
compare
MMJJ
_RS05610
-2.7
-5.2
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMJJ
_RS08850
-2.7
-3.3
succinate dehydrogenase/fumarate reductase iron-sulfur subunit
compare
MMJJ
_RS05380
-2.7
-2.1
hypothetical protein
compare
MMJJ
_RS04730
-2.7
-3.7
tyrosine decarboxylase MfnA
compare
MMJJ
_RS06510
-2.7
-3.7
LL-diaminopimelate aminotransferase
compare
MMJJ
_RS00125
-2.7
-3.1
KEOPS complex subunit Cgi121
compare
MMJJ
_RS05490
-2.7
-3.8
imidazole glycerol phosphate synthase subunit HisF
compare
MMJJ
_RS04155
-2.7
-7.8
hypothetical protein
compare
MMJJ
_RS06785
-2.7
-8.8
RNA ligase partner protein
compare
MMJJ
_RS05070
-2.6
-3.0
DNA primase catalytic subunit PriS
compare
MMJJ
_RS05995
-2.6
-2.7
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS07190
-2.6
-5.3
RtcB family protein
compare
MMJJ
_RS07785
-2.6
-4.0
fumarate reductase subunit A
compare
MMJJ
_RS06390
-2.6
-2.8
NADPH-dependent F420 reductase
compare
MMJJ
_RS06155
-2.6
-6.6
phosphatidylglycerophosphatase A
compare
MMJJ
_RS03115
-2.6
-6.6
sulfopyruvate decarboxylase subunit alpha
compare
MMJJ
_RS06930
-2.6
-4.2
type II methionyl aminopeptidase
compare
MMJJ
_RS07945
-2.6
-3.0
4Fe-4S binding protein
compare
MMJJ
_RS07950
-2.5
-3.3
4Fe-4S binding protein
compare
MMJJ
_RS07725
-2.5
-7.4
DNA primase DnaG
compare
MMJJ
_RS07410
-2.5
-4.1
methanogenesis marker protein Mmp4/MtxX
compare
MMJJ
_RS04675
-2.5
-6.3
thiamine pyrophosphate-binding protein
compare
MMJJ
_RS01360
-2.5
-3.2
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMJJ
_RS07660
-2.5
-9.2
carbonic anhydrase
compare
MMJJ
_RS07355
-2.4
-7.2
MoaD/ThiS family protein
compare
MMJJ
_RS06380
-2.4
-5.0
signal recognition particle protein Srp54
compare
MMJJ
_RS08840
-2.4
-5.5
calcium/sodium antiporter
compare
MMJJ
_RS03800
-2.4
-10.6
aldolase
compare
MMJJ
_RS09190
-2.4
-2.9
tryptophan synthase subunit beta
compare
MMJJ
_RS05655
-2.4
-6.5
HisA/HisF family protein
compare
MMJJ
_RS04970
-2.4
-2.7
DUF655 domain-containing protein
compare
MMJJ
_RS07245
-2.4
-6.3
amidohydrolase family protein
compare
MMJJ
_RS03630
-2.4
-13.5
AMP phosphorylase
compare
MMJJ
_RS05065
-2.4
-4.6
(4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase
compare
MMJJ
_RS05225
-2.4
-2.4
Gar1/Naf1 family protein
compare
MMJJ
_RS01415
-2.4
-3.6
beta-CASP ribonuclease aCPSF1
compare
MMJJ
_RS07350
-2.4
-4.0
4Fe-4S binding protein
compare
MMJJ
_RS07470
-2.4
-2.9
50S ribosome-binding GTPase
compare
MMJJ
_RS04485
-2.4
-8.0
riboflavin synthase
compare
MMJJ
_RS07635
-2.3
-12.9
response regulator transcription factor
compare
MMJJ
_RS06905
-2.3
-2.7
hypothetical protein
compare
MMJJ
_RS06185
-2.3
-5.3
cobalamin biosynthesis protein
compare
MMJJ
_RS00360
-2.3
-4.0
adenosylhomocysteinase
compare
MMJJ
_RS06835
-2.3
-11.2
4Fe-4S binding protein
compare
MMJJ
_RS07640
-2.3
-17.9
cache domain-containing protein
compare
MMJJ
_RS04995
-2.3
-6.1
Tfx family DNA-binding protein
compare
MMJJ
_RS08340
-2.3
-4.9
archaeoflavoprotein AfpA
compare
MMJJ
_RS00370
-2.3
-2.7
asparagine synthase (glutamine-hydrolyzing)
compare
MMJJ
_RS03660
-2.3
-3.4
DUF447 family protein
compare
MMJJ
_RS03065
-2.2
-11.3
CBS domain-containing protein
compare
MMJJ
_RS00205
-2.2
-6.2
adenosylcobinamide-phosphate synthase CbiB
compare
MMJJ
_RS04875
-2.2
-2.2
tRNA-Lys
compare
MMJJ
_RS06240
-2.2
-2.4
dihydropteroate synthase-like protein
compare
MMJJ
_RS00050
-2.2
-10.5
AAA family ATPase
compare
MMJJ
_RS08660
-2.2
-4.3
acetylornithine transaminase
compare
MMJJ
_RS05810
-2.2
-7.0
precorrin-4 C(11)-methyltransferase
compare
MMJJ
_RS07370
-2.2
-3.8
tRNA 4-thiouridine(8) synthase ThiI
compare
MMJJ
_RS07995
-2.2
-5.9
molybdenum cofactor biosynthesis protein MoaE
compare
MMJJ
_RS03965
-2.2
-2.3
DNA-directed RNA polymerase subunit L
compare
MMJJ
_RS08795
-2.2
-3.6
phosphoglucosamine mutase
compare
MMJJ
_RS01355
-2.1
-3.8
UDP-N-acetyl-D-mannosamine dehydrogenase
compare
MMJJ
_RS02035
-2.1
-7.0
4-hydroxy-tetrahydrodipicolinate synthase
compare
MMJJ
_RS00070
-2.1
-3.8
CooT family nickel-binding protein
compare
MMJJ
_RS04985
-2.1
-5.1
glutamyl-tRNA reductase
compare
MMJJ
_RS06225
-2.1
-2.4
adenosylmethionine decarboxylase
compare
MMJJ
_RS07345
-2.1
-6.2
homocysteine biosynthesis protein
compare
MMJJ
_RS00195
-2.1
-4.2
precorrin-3B C(17)-methyltransferase
compare
MMJJ
_RS04595
-2.1
-4.1
hypothetical protein
compare
MMJJ
_RS00530
-2.1
-11.1
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS07650
-2.1
-14.4
formate/nitrite transporter family protein
compare
MMJJ
_RS07155
-2.1
-8.0
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMJJ
_RS06750
-2.1
-3.4
homoaconitase large subunit
compare
MMJJ
_RS00040
-2.0
-9.8
CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
compare
MMJJ
_RS05190
-2.0
-8.7
gamma carbonic anhydrase family protein
compare
MMJJ
_RS00060
-2.0
-13.7
acetyl-CoA decarbonylase/synthase complex subunit gamma
compare
MMJJ
_RS00035
-2.0
-13.2
CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
compare
MMJJ
_RS02055
-2.0
-11.0
GTP 3',8-cyclase MoaA
compare
MMJJ
_RS00265
-2.0
-7.0
TIGR02253 family HAD-type hydrolase
compare
MMJJ
_RS06220
-2.0
-5.8
polyamine aminopropyltransferase
compare
MMJJ
_RS00600
-2.0
-3.7
hydroxymethylbilane synthase
compare
MMJJ
_RS00045
-2.0
-10.9
CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
compare
MMJJ
_RS00075
-2.0
-11.1
AAA family ATPase
compare
MMJJ
_RS05375
-1.9
-13.8
radical SAM protein
compare
MMJJ
_RS04010
-1.9
-7.5
archaeal proteasome endopeptidase complex subunit alpha
compare
MMJJ
_RS04670
-1.9
-6.1
DUF2117 domain-containing protein
compare
MMJJ
_RS06170
-1.9
-7.6
hypothetical protein
compare
MMJJ
_RS00515
-1.9
-10.6
cobalt transporter CbiM
compare
MMJJ
_RS06050
-1.9
-8.5
molybdopterin molybdotransferase MoeA
compare
MMJJ
_RS01880
-1.9
-2.8
RlmE family RNA methyltransferase
compare
MMJJ
_RS03500
-1.9
-10.7
F420-dependent methylenetetrahydromethanopterin dehydrogenase
compare
MMJJ
_RS00080
-1.8
-11.3
DUF166 domain-containing protein
compare
MMJJ
_RS05295
-1.8
-8.0
cobyrinic acid a,c-diamide synthase
compare
MMJJ
_RS06215
-1.8
-4.3
agmatinase
compare
MMJJ
_RS04980
-1.8
-3.4
bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase
compare
MMJJ
_RS05765
-1.8
-1.6
flagellar protein E
compare
MMJJ
_RS06030
-1.8
-5.1
4Fe-4S binding protein
compare
MMJJ
_RS06865
-1.8
-2.5
NADH-quinone oxidoreductase subunit H
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments