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Experiment set3IT042 for
Methanococcus maripaludis JJ
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formate McAA pyroxidine HCl dropout
200 most detrimental genes:
gene
name
fitness
t score
description
MMJJ
_RS04415
+2.6
9.5
hypothetical protein
compare
MMJJ
_RS04005
+0.9
7.3
acetate--CoA ligase family protein
compare
MMJJ
_RS08130
+0.8
0.9
translation initiation factor IF-2 subunit gamma
compare
MMJJ
_RS03725
+0.7
3.4
sulfurtransferase TusA family protein
compare
MMJJ
_RS08830
+0.7
2.8
hypothetical protein
compare
MMJJ
_RS09120
+0.6
1.3
aspartate kinase
compare
MMJJ
_RS07230
+0.6
4.3
coenzyme F420-reducing hydrogenase, FrhD protein
compare
MMJJ
_RS07015
+0.6
1.0
PFL family protein
compare
MMJJ
_RS06675
+0.6
5.0
TIGR01212 family radical SAM protein
compare
MMJJ
_RS07920
+0.6
3.8
6-carboxytetrahydropterin synthase QueD
compare
MMJJ
_RS07235
+0.6
4.8
coenzyme F420 hydrogenase subunit alpha
compare
MMJJ
_RS06210
+0.6
3.6
hypothetical protein
compare
MMJJ
_RS07935
+0.6
0.6
protein fwdD
compare
MMJJ
_RS04955
+0.5
3.8
tRNA pseudouridine(54/55) synthase Pus10
compare
MMJJ
_RS07220
+0.5
4.3
coenzyme F420 hydrogenase subunit beta
compare
MMJJ
_RS09405
+0.5
1.7
hypothetical protein
compare
MMJJ
_RS05685
+0.5
3.1
class III signal peptide-containing protein
compare
MMJJ
_RS06190
+0.5
3.6
7-cyano-7-deazaguanine synthase
compare
MMJJ
_RS06090
+0.5
3.4
hypothetical protein
compare
MMJJ
_RS06950
+0.5
3.2
4-demethylwyosine synthase TYW1
compare
MMJJ
_RS06275
+0.5
2.3
hypothetical protein
compare
MMJJ
_RS06460
+0.5
2.9
cytochrome c
compare
MMJJ
_RS06680
+0.4
2.4
DUF366 family protein
compare
MMJJ
_RS08410
+0.4
0.8
CBS domain-containing protein
compare
MMJJ
_RS04545
+0.4
1.1
PadR family transcriptional regulator
compare
MMJJ
_RS06505
+0.4
1.6
prephenate dehydratase
compare
MMJJ
_RS08935
+0.4
0.7
TIGR00288 family NYN domain-containing protein
compare
MMJJ
_RS04850
+0.4
2.6
energy-coupling factor transporter transmembrane protein EcfT
compare
MMJJ
_RS06500
+0.4
2.5
class I SAM-dependent methyltransferase
compare
MMJJ
_RS06430
+0.4
2.4
haloacid dehalogenase
compare
MMJJ
_RS07025
+0.4
2.5
tRNA (cytidine(56)-2'-O)-methyltransferase
compare
MMJJ
_RS01855
+0.4
3.0
MBL fold metallo-hydrolase
compare
MMJJ
_RS04105
+0.4
3.3
prepilin peptidase
compare
MMJJ
_RS07240
+0.4
3.5
MBL fold metallo-hydrolase
compare
MMJJ
_RS03605
+0.4
1.9
TIGR00297 family protein
compare
MMJJ
_RS00500
+0.4
1.6
GNAT family N-acetyltransferase
compare
MMJJ
_RS05040
+0.4
2.7
7-carboxy-7-deazaguanine synthase QueE
compare
MMJJ
_RS07260
+0.4
2.5
PspC domain-containing protein
compare
MMJJ
_RS07765
+0.4
1.3
DMT family protein
compare
MMJJ
_RS06280
+0.4
3.0
hypothetical protein
compare
MMJJ
_RS07225
+0.4
2.9
coenzyme F420 hydrogenase subunit gamma
compare
MMJJ
_RS06440
+0.4
2.5
DUF4870 domain-containing protein
compare
MMJJ
_RS03375
+0.4
2.4
hypothetical protein
compare
MMJJ
_RS05580
+0.4
2.6
methanogenesis marker 9 domain-containing protein
compare
MMJJ
_RS09050
+0.4
1.9
hypothetical protein
compare
MMJJ
_RS08100
+0.4
2.1
hypothetical protein
compare
MMJJ
_RS00115
+0.4
1.6
hypothetical protein
compare
MMJJ
_RS02665
+0.4
1.5
methyl-accepting chemotaxis protein
compare
MMJJ
_RS08525
+0.4
2.3
peptidylprolyl isomerase
compare
MMJJ
_RS03775
+0.3
1.7
50S ribosomal protein L15e
compare
MMJJ
_RS05695
+0.3
1.3
class III signal peptide-containing protein
compare
MMJJ
_RS06205
+0.3
2.6
EamA family transporter
compare
MMJJ
_RS05510
+0.3
2.6
archaellum operon transcriptional activator EarA family protein
compare
MMJJ
_RS09295
+0.3
0.4
hypothetical protein
compare
MMJJ
_RS01825
+0.3
2.0
DNA repair and recombination protein RadB
compare
MMJJ
_RS05525
+0.3
2.0
GTP-binding protein
compare
MMJJ
_RS07680
+0.3
2.2
glucose-6-phosphate isomerase
compare
MMJJ
_RS04365
+0.3
1.9
helix-turn-helix transcriptional regulator
compare
MMJJ
_RS07210
+0.3
2.4
AmmeMemoRadiSam system protein B
compare
MMJJ
_RS06580
+0.3
2.6
alanine dehydrogenase
compare
MMJJ
_RS06120
+0.3
2.5
DUF4013 domain-containing protein
compare
MMJJ
_RS06810
+0.3
2.5
L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha
compare
MMJJ
_RS06735
+0.3
2.1
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS06770
+0.3
2.6
hypothetical protein
compare
MMJJ
_RS07740
+0.3
2.3
DUF2334 domain-containing protein
compare
MMJJ
_RS06960
+0.3
2.8
CAP domain-containing protein
compare
MMJJ
_RS06685
+0.3
2.7
S-layer protein
compare
MMJJ
_RS07480
+0.3
2.5
FAD-dependent oxidoreductase
compare
MMJJ
_RS00405
+0.3
2.0
flavodoxin family protein
compare
MMJJ
_RS06535
+0.3
2.5
UPF0104 family protein
compare
MMJJ
_RS08305
+0.3
1.4
peroxiredoxin
compare
MMJJ
_RS05350
+0.3
1.5
DUF192 domain-containing protein
compare
MMJJ
_RS03595
+0.3
1.8
hypothetical protein
compare
MMJJ
_RS07200
+0.3
2.4
MFS transporter
compare
MMJJ
_RS01590
+0.3
0.8
adenine phosphoribosyltransferase
compare
MMJJ
_RS01010
+0.3
2.8
right-handed parallel beta-helix repeat-containing protein
compare
MMJJ
_RS06085
+0.3
1.7
proteasome assembly chaperone family protein
compare
MMJJ
_RS07985
+0.3
1.4
hypothetical protein
compare
MMJJ
_RS05530
+0.3
1.3
roadblock/LC7 domain-containing protein
compare
MMJJ
_RS07795
+0.3
1.8
cupin domain-containing protein
compare
MMJJ
_RS09365
+0.3
0.6
hypothetical protein
compare
MMJJ
_RS03575
+0.3
1.6
NUDIX hydrolase
compare
MMJJ
_RS03835
+0.3
1.1
DUF504 domain-containing protein
compare
MMJJ
_RS07835
+0.3
2.1
UPF0489 family protein
compare
MMJJ
_RS03515
+0.3
1.7
GPR1/FUN34/YaaH family transporter
compare
MMJJ
_RS02285
+0.3
1.0
class III signal peptide-containing protein
compare
MMJJ
_RS07815
+0.3
1.9
2-oxoacid:acceptor oxidoreductase family protein
compare
MMJJ
_RS09325
+0.3
1.4
hypothetical protein
compare
MMJJ
_RS06235
+0.3
2.2
IGHMBP2 family helicase
compare
MMJJ
_RS06710
+0.3
2.1
TldD/PmbA family protein
compare
MMJJ
_RS06640
+0.3
1.8
YfcE family phosphodiesterase
compare
MMJJ
_RS07760
+0.3
1.4
GNAT family N-acetyltransferase
compare
MMJJ
_RS02240
+0.3
1.0
CGGC domain-containing protein
compare
MMJJ
_RS03245
+0.3
0.2
UMP kinase
compare
MMJJ
_RS06080
+0.3
1.8
serine/threonine protein kinase
compare
MMJJ
_RS04135
+0.2
1.2
7-cyano-7-deazaguanine synthase QueC
compare
MMJJ
_RS06745
+0.2
1.5
energy-coupling factor ABC transporter permease
compare
MMJJ
_RS02355
+0.2
1.7
DUF2798 domain-containing protein
compare
MMJJ
_RS04625
+0.2
1.9
SLC13 family permease
compare
MMJJ
_RS06495
+0.2
0.5
hypothetical protein
compare
MMJJ
_RS00150
+0.2
1.3
DUF2180 family protein
compare
MMJJ
_RS07445
+0.2
1.9
RlmF-related methyltransferase
compare
MMJJ
_RS06790
+0.2
2.0
nucleotidyltransferase family protein
compare
MMJJ
_RS09360
+0.2
1.8
hypothetical protein
compare
MMJJ
_RS04290
+0.2
1.3
hypothetical protein
compare
MMJJ
_RS04235
+0.2
1.5
molybdate ABC transporter permease subunit
compare
MMJJ
_RS04215
+0.2
1.9
DMT family transporter
compare
MMJJ
_RS09390
+0.2
0.7
hypothetical protein
compare
MMJJ
_RS07800
+0.2
1.8
AMP-binding protein
compare
MMJJ
_RS00155
+0.2
1.9
DUF2193 domain-containing protein
compare
MMJJ
_RS06515
+0.2
1.7
ribonuclease III
compare
MMJJ
_RS01395
+0.2
1.3
DUF1894 domain-containing protein
compare
MMJJ
_RS08485
+0.2
1.1
Lrp/AsnC family transcriptional regulator
compare
MMJJ
_RS07855
+0.2
1.7
YkgJ family cysteine cluster protein
compare
MMJJ
_RS06445
+0.2
2.0
hypothetical protein
compare
MMJJ
_RS00145
+0.2
1.8
aquaporin family protein
compare
MMJJ
_RS06800
+0.2
1.3
prefoldin subunit alpha
compare
MMJJ
_RS06385
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS01140
+0.2
1.0
helix-turn-helix domain-containing protein
compare
MMJJ
_RS03350
+0.2
0.6
hypothetical protein
compare
MMJJ
_RS07005
+0.2
1.1
transcription factor S
compare
MMJJ
_RS00400
+0.2
1.0
tautomerase family protein
compare
MMJJ
_RS05500
+0.2
2.0
hypothetical protein
compare
MMJJ
_RS07205
+0.2
1.1
MTH895/ArsE family thioredoxin-like protein
compare
MMJJ
_RS00630
+0.2
1.5
betaine/proline/choline family ABC transporter ATP-binding protein
compare
MMJJ
_RS04300
+0.2
1.4
hypothetical protein
compare
MMJJ
_RS05200
+0.2
1.7
TIGR04013 family B12-binding domain/radical SAM domain-containing protein
compare
MMJJ
_RS07810
+0.2
1.5
3-methyl-2-oxobutanoate dehydrogenase subunit VorB
compare
MMJJ
_RS06765
+0.2
1.8
hypothetical protein
compare
MMJJ
_RS08810
+0.2
0.3
DUF4040 domain-containing protein
compare
MMJJ
_RS04375
+0.2
0.9
hypothetical protein
compare
MMJJ
_RS05690
+0.2
1.9
hypothetical protein
compare
MMJJ
_RS07365
+0.2
1.6
CatB-related O-acetyltransferase
compare
MMJJ
_RS07830
+0.2
1.4
DUF1786 domain-containing protein
compare
MMJJ
_RS01670
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS05975
+0.2
1.2
sulfurtransferase TusA family protein
compare
MMJJ
_RS01955
+0.2
1.7
hypothetical protein
compare
MMJJ
_RS04500
+0.2
1.5
hypothetical protein
compare
MMJJ
_RS05705
+0.2
1.6
hypothetical protein
compare
MMJJ
_RS07915
+0.2
1.0
CBS domain-containing protein
compare
MMJJ
_RS04560
+0.2
1.4
ABC transporter permease
compare
MMJJ
_RS08285
+0.2
1.6
class I SAM-dependent methyltransferase
compare
MMJJ
_RS05340
+0.2
1.6
AAA family ATPase
compare
MMJJ
_RS06590
+0.2
1.6
sodium:alanine symporter family protein
compare
MMJJ
_RS01835
+0.2
1.6
tRNA pseudouridine(13) synthase TruD
compare
MMJJ
_RS01790
+0.2
1.4
pyridoxamine 5'-phosphate oxidase family protein
compare
MMJJ
_RS02115
+0.2
1.4
class I SAM-dependent methyltransferase family protein
compare
MMJJ
_RS05585
+0.2
1.5
hypothetical protein
compare
MMJJ
_RS08350
+0.2
1.7
heavy metal translocating P-type ATPase
compare
MMJJ
_RS08225
+0.2
0.8
peptidylprolyl isomerase
compare
MMJJ
_RS09065
+0.2
1.2
hypothetical protein
compare
MMJJ
_RS05700
+0.2
1.3
metallophosphoesterase
compare
MMJJ
_RS04345
+0.2
0.8
DUF2080 family transposase-associated protein
compare
MMJJ
_RS08420
+0.2
1.6
uroporphyrinogen decarboxylase family protein
compare
MMJJ
_RS09005
+0.2
1.7
N-6 DNA methylase
compare
MMJJ
_RS05400
+0.2
0.9
CoA-binding protein
compare
MMJJ
_RS06105
+0.2
1.3
DUF99 family protein
compare
MMJJ
_RS05355
+0.2
1.4
DUF2121 domain-containing protein
compare
MMJJ
_RS02335
+0.2
1.6
ABC transporter substrate-binding protein
compare
MMJJ
_RS06555
+0.2
1.4
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS03825
+0.2
1.3
DUF1624 domain-containing protein
compare
MMJJ
_RS05960
+0.2
1.3
DUF169 domain-containing protein
compare
MMJJ
_RS06470
+0.2
1.4
tripartite tricarboxylate transporter permease
compare
MMJJ
_RS03070
+0.2
0.6
MetS family NSS transporter small subunit
compare
MMJJ
_RS00780
+0.2
1.4
M48 family metallopeptidase
compare
MMJJ
_RS01920
+0.2
1.5
phosphoglycerate mutase
compare
MMJJ
_RS07820
+0.2
1.3
bifunctional hexulose-6-phosphate synthase/ribonuclease regulator
compare
MMJJ
_RS06550
+0.2
1.4
ABC transporter permease
compare
MMJJ
_RS03940
+0.2
1.1
DMT family transporter
compare
MMJJ
_RS03040
+0.2
1.3
lactate utilization protein
compare
MMJJ
_RS02160
+0.2
1.2
amino acid ABC transporter permease
compare
MMJJ
_RS08745
+0.2
1.3
glycosyltransferase family 9 protein
compare
MMJJ
_RS03735
+0.2
1.3
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
MMJJ
_RS08370
+0.2
0.7
hypothetical protein
compare
MMJJ
_RS05505
+0.2
1.6
hypothetical protein
compare
MMJJ
_RS05115
+0.2
0.7
P-II family nitrogen regulator
compare
MMJJ
_RS02165
+0.2
1.1
ABC transporter substrate-binding protein
compare
MMJJ
_RS07175
+0.2
1.3
DEAD/DEAH box helicase
compare
MMJJ
_RS07695
+0.2
1.4
glycoside hydrolase family 15 protein
compare
MMJJ
_RS05390
+0.2
1.3
tRNA pseudouridine(13) synthase TruD
compare
MMJJ
_RS04950
+0.2
1.3
TIGR00375 family protein
compare
MMJJ
_RS01065
+0.2
1.2
DUF1700 domain-containing protein
compare
MMJJ
_RS02270
+0.2
0.8
HEPN domain-containing protein
compare
MMJJ
_RS03905
+0.2
0.8
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS05990
+0.2
1.0
phosphatase PAP2 family protein
compare
MMJJ
_RS02295
+0.2
1.3
hypothetical protein
compare
MMJJ
_RS05520
+0.2
1.2
H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein
compare
MMJJ
_RS05090
+0.2
0.9
MGMT family protein
compare
MMJJ
_RS05105
+0.2
1.0
P-II family nitrogen regulator
compare
MMJJ
_RS08045
+0.1
1.2
transporter substrate-binding domain-containing protein
compare
MMJJ
_RS01100
+0.1
0.3
helix-turn-helix domain-containing protein
compare
MMJJ
_RS06740
+0.1
0.8
energy-coupling factor ABC transporter substrate-binding protein
compare
MMJJ
_RS00745
+0.1
0.5
hypothetical protein
compare
MMJJ
_RS03395
+0.1
0.4
hypothetical protein
compare
MMJJ
_RS04175
+0.1
0.9
hypothetical protein
compare
MMJJ
_RS06585
+0.1
1.0
alanine racemase
compare
MMJJ
_RS07610
+0.1
0.9
DUF2119 domain-containing protein
compare
MMJJ
_RS08565
+0.1
1.2
ATP-binding protein
compare
MMJJ
_RS09205
+0.1
0.6
hypothetical protein
compare
MMJJ
_RS03045
+0.1
1.1
hypothetical protein
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments