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Experiment set3IT041 for
Methanococcus maripaludis JJ
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formate McAA pyroxidine HCl dropout
200 most detrimental genes:
gene
name
fitness
t score
description
MMJJ
_RS04415
+2.9
8.9
hypothetical protein
compare
MMJJ
_RS08935
+1.2
2.3
TIGR00288 family NYN domain-containing protein
compare
MMJJ
_RS03725
+1.0
2.3
sulfurtransferase TusA family protein
compare
MMJJ
_RS04005
+0.9
6.4
acetate--CoA ligase family protein
compare
MMJJ
_RS07185
+0.9
2.2
DUF371 domain-containing protein
compare
MMJJ
_RS07015
+0.8
1.0
PFL family protein
compare
MMJJ
_RS06495
+0.8
2.9
hypothetical protein
compare
MMJJ
_RS05280
+0.7
1.1
hypothetical protein
compare
MMJJ
_RS06675
+0.7
5.5
TIGR01212 family radical SAM protein
compare
MMJJ
_RS05530
+0.6
2.4
roadblock/LC7 domain-containing protein
compare
MMJJ
_RS07935
+0.6
0.7
protein fwdD
compare
MMJJ
_RS08410
+0.6
2.1
CBS domain-containing protein
compare
MMJJ
_RS09405
+0.6
1.9
hypothetical protein
compare
MMJJ
_RS07915
+0.6
2.6
CBS domain-containing protein
compare
MMJJ
_RS07230
+0.6
3.5
coenzyme F420-reducing hydrogenase, FrhD protein
compare
MMJJ
_RS06680
+0.6
3.2
DUF366 family protein
compare
MMJJ
_RS04955
+0.6
3.4
tRNA pseudouridine(54/55) synthase Pus10
compare
MMJJ
_RS07260
+0.5
3.1
PspC domain-containing protein
compare
MMJJ
_RS06275
+0.5
2.5
hypothetical protein
compare
MMJJ
_RS09295
+0.5
0.6
hypothetical protein
compare
MMJJ
_RS03835
+0.5
2.0
DUF504 domain-containing protein
compare
MMJJ
_RS06385
+0.5
2.5
hypothetical protein
compare
MMJJ
_RS06460
+0.5
2.9
cytochrome c
compare
MMJJ
_RS07235
+0.5
3.8
coenzyme F420 hydrogenase subunit alpha
compare
MMJJ
_RS09265
+0.5
1.4
hypothetical protein
compare
MMJJ
_RS09365
+0.5
1.3
hypothetical protein
compare
MMJJ
_RS06500
+0.4
2.7
class I SAM-dependent methyltransferase
compare
MMJJ
_RS06950
+0.4
2.7
4-demethylwyosine synthase TYW1
compare
MMJJ
_RS07920
+0.4
2.6
6-carboxytetrahydropterin synthase QueD
compare
MMJJ
_RS06515
+0.4
3.2
ribonuclease III
compare
MMJJ
_RS06810
+0.4
3.2
L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha
compare
MMJJ
_RS06540
+0.4
1.0
DUF2120 domain-containing protein
compare
MMJJ
_RS06190
+0.4
3.1
7-cyano-7-deazaguanine synthase
compare
MMJJ
_RS05685
+0.4
2.5
class III signal peptide-containing protein
compare
MMJJ
_RS06735
+0.4
2.8
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS07445
+0.4
2.9
RlmF-related methyltransferase
compare
MMJJ
_RS04345
+0.4
1.6
DUF2080 family transposase-associated protein
compare
MMJJ
_RS06090
+0.4
2.3
hypothetical protein
compare
MMJJ
_RS07270
+0.4
2.7
ribonuclease HII
compare
MMJJ
_RS06740
+0.4
1.9
energy-coupling factor ABC transporter substrate-binding protein
compare
MMJJ
_RS01140
+0.4
2.5
helix-turn-helix domain-containing protein
compare
MMJJ
_RS01405
+0.4
0.3
proline--tRNA ligase
compare
MMJJ
_RS07225
+0.4
2.4
coenzyme F420 hydrogenase subunit gamma
compare
MMJJ
_RS07220
+0.4
3.0
coenzyme F420 hydrogenase subunit beta
compare
MMJJ
_RS04850
+0.4
1.9
energy-coupling factor transporter transmembrane protein EcfT
compare
MMJJ
_RS04105
+0.4
3.1
prepilin peptidase
compare
MMJJ
_RS07595
+0.4
1.4
hypothetical protein
compare
MMJJ
_RS08100
+0.4
2.1
hypothetical protein
compare
MMJJ
_RS06765
+0.4
3.0
hypothetical protein
compare
MMJJ
_RS07825
+0.4
1.2
YciI family protein
compare
MMJJ
_RS06590
+0.4
2.5
sodium:alanine symporter family protein
compare
MMJJ
_RS03375
+0.3
1.7
hypothetical protein
compare
MMJJ
_RS05520
+0.3
2.6
H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein
compare
MMJJ
_RS07215
+0.3
2.7
TIGR00341 family protein
compare
MMJJ
_RS01010
+0.3
3.2
right-handed parallel beta-helix repeat-containing protein
compare
MMJJ
_RS07480
+0.3
2.5
FAD-dependent oxidoreductase
compare
MMJJ
_RS03805
+0.3
1.4
hypothetical protein
compare
MMJJ
_RS07805
+0.3
1.6
ferredoxin family protein
compare
MMJJ
_RS07820
+0.3
2.3
bifunctional hexulose-6-phosphate synthase/ribonuclease regulator
compare
MMJJ
_RS06640
+0.3
2.1
YfcE family phosphodiesterase
compare
MMJJ
_RS05975
+0.3
1.8
sulfurtransferase TusA family protein
compare
MMJJ
_RS06745
+0.3
1.8
energy-coupling factor ABC transporter permease
compare
MMJJ
_RS04215
+0.3
2.7
DMT family transporter
compare
MMJJ
_RS06205
+0.3
2.3
EamA family transporter
compare
MMJJ
_RS07815
+0.3
2.1
2-oxoacid:acceptor oxidoreductase family protein
compare
MMJJ
_RS08490
+0.3
1.2
rubrerythrin family protein
compare
MMJJ
_RS07240
+0.3
2.7
MBL fold metallo-hydrolase
compare
MMJJ
_RS09230
+0.3
1.2
hypothetical protein
compare
MMJJ
_RS07210
+0.3
2.4
AmmeMemoRadiSam system protein B
compare
MMJJ
_RS06440
+0.3
2.0
DUF4870 domain-containing protein
compare
MMJJ
_RS07025
+0.3
2.1
tRNA (cytidine(56)-2'-O)-methyltransferase
compare
MMJJ
_RS05970
+0.3
1.0
MJ0307 family thioredoxin
compare
MMJJ
_RS07005
+0.3
1.4
transcription factor S
compare
MMJJ
_RS06710
+0.3
2.4
TldD/PmbA family protein
compare
MMJJ
_RS04965
+0.3
0.7
RNA polymerase Rpb4 family protein
compare
MMJJ
_RS06210
+0.3
1.6
hypothetical protein
compare
MMJJ
_RS06960
+0.3
2.5
CAP domain-containing protein
compare
MMJJ
_RS05040
+0.3
2.2
7-carboxy-7-deazaguanine synthase QueE
compare
MMJJ
_RS08370
+0.3
1.9
hypothetical protein
compare
MMJJ
_RS04780
+0.3
1.0
nucleic acid-binding protein
compare
MMJJ
_RS06580
+0.3
2.0
alanine dehydrogenase
compare
MMJJ
_RS02355
+0.3
2.0
DUF2798 domain-containing protein
compare
MMJJ
_RS09255
+0.3
0.9
hypothetical protein
compare
MMJJ
_RS03905
+0.3
1.8
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS06120
+0.3
1.7
DUF4013 domain-containing protein
compare
MMJJ
_RS06770
+0.3
2.0
hypothetical protein
compare
MMJJ
_RS06685
+0.3
2.2
S-layer protein
compare
MMJJ
_RS03070
+0.3
1.2
MetS family NSS transporter small subunit
compare
MMJJ
_RS01790
+0.3
1.8
pyridoxamine 5'-phosphate oxidase family protein
compare
MMJJ
_RS08365
+0.3
1.5
DsrE family protein
compare
MMJJ
_RS05980
+0.3
1.6
DUF5400 domain-containing protein
compare
MMJJ
_RS01300
+0.3
1.6
MarR family transcriptional regulator
compare
MMJJ
_RS05660
+0.3
1.5
sulfopyruvate decarboxylase subunit beta
compare
MMJJ
_RS01795
+0.3
1.4
TIGR00266 family protein
compare
MMJJ
_RS04390
+0.3
1.9
rhomboid family intramembrane serine protease
compare
MMJJ
_RS07450
+0.3
1.4
hypothetical protein
compare
MMJJ
_RS06585
+0.3
1.5
alanine racemase
compare
MMJJ
_RS03360
+0.3
0.5
hypothetical protein
compare
MMJJ
_RS01785
+0.3
0.4
50S ribosomal protein L14e
compare
MMJJ
_RS03595
+0.3
1.6
hypothetical protein
compare
MMJJ
_RS08375
+0.3
1.9
ferritin
compare
MMJJ
_RS01395
+0.3
1.2
DUF1894 domain-containing protein
compare
MMJJ
_RS07010
+0.3
1.4
preprotein translocase subunit Sec61beta
compare
MMJJ
_RS07810
+0.3
1.5
3-methyl-2-oxobutanoate dehydrogenase subunit VorB
compare
MMJJ
_RS05390
+0.3
1.8
tRNA pseudouridine(13) synthase TruD
compare
MMJJ
_RS00145
+0.2
1.8
aquaporin family protein
compare
MMJJ
_RS04500
+0.2
1.6
hypothetical protein
compare
MMJJ
_RS00155
+0.2
2.0
DUF2193 domain-containing protein
compare
MMJJ
_RS08030
+0.2
1.5
hypothetical protein
compare
MMJJ
_RS03540
+0.2
0.9
TIGR00289 family protein
compare
MMJJ
_RS04545
+0.2
0.6
PadR family transcriptional regulator
compare
MMJJ
_RS03350
+0.2
0.4
hypothetical protein
compare
MMJJ
_RS08350
+0.2
2.1
heavy metal translocating P-type ATPase
compare
MMJJ
_RS04365
+0.2
1.2
helix-turn-helix transcriptional regulator
compare
MMJJ
_RS03730
+0.2
1.1
SWIM zinc finger family protein
compare
MMJJ
_RS08025
+0.2
0.8
hypothetical protein
compare
MMJJ
_RS01855
+0.2
1.9
MBL fold metallo-hydrolase
compare
MMJJ
_RS07795
+0.2
1.1
cupin domain-containing protein
compare
MMJJ
_RS05365
+0.2
1.4
DUF2798 domain-containing protein
compare
MMJJ
_RS09390
+0.2
1.3
hypothetical protein
compare
MMJJ
_RS09325
+0.2
1.5
hypothetical protein
compare
MMJJ
_RS01430
+0.2
1.4
hypothetical protein
compare
MMJJ
_RS05585
+0.2
1.5
hypothetical protein
compare
MMJJ
_RS00745
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS08160
+0.2
1.0
tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO
compare
MMJJ
_RS05700
+0.2
1.6
metallophosphoesterase
compare
MMJJ
_RS01270
+0.2
1.4
4Fe-4S binding protein
compare
MMJJ
_RS06555
+0.2
1.7
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS07610
+0.2
1.1
DUF2119 domain-containing protein
compare
MMJJ
_RS03445
+0.2
1.3
hypothetical protein
compare
MMJJ
_RS07200
+0.2
1.5
MFS transporter
compare
MMJJ
_RS05990
+0.2
1.3
phosphatase PAP2 family protein
compare
MMJJ
_RS06100
+0.2
1.4
rubrerythrin
compare
MMJJ
_RS08285
+0.2
1.5
class I SAM-dependent methyltransferase
compare
MMJJ
_RS04635
+0.2
1.0
DUF367 family protein
compare
MMJJ
_RS06450
+0.2
1.5
DUF3343 domain-containing protein
compare
MMJJ
_RS07800
+0.2
1.7
AMP-binding protein
compare
MMJJ
_RS05500
+0.2
1.8
hypothetical protein
compare
MMJJ
_RS05405
+0.2
1.4
DNA cytosine methyltransferase
compare
MMJJ
_RS06445
+0.2
1.7
hypothetical protein
compare
MMJJ
_RS08015
+0.2
1.0
HAD family hydrolase
compare
MMJJ
_RS07695
+0.2
1.6
glycoside hydrolase family 15 protein
compare
MMJJ
_RS03735
+0.2
1.4
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
MMJJ
_RS06800
+0.2
1.1
prefoldin subunit alpha
compare
MMJJ
_RS05605
+0.2
0.9
hypothetical protein
compare
MMJJ
_RS08045
+0.2
1.6
transporter substrate-binding domain-containing protein
compare
MMJJ
_RS08275
+0.2
1.8
iron ABC transporter substrate-binding protein
compare
MMJJ
_RS08225
+0.2
0.6
peptidylprolyl isomerase
compare
MMJJ
_RS01715
+0.2
1.0
winged helix-turn-helix domain-containing protein
compare
MMJJ
_RS08310
+0.2
1.0
ZIP family metal transporter
compare
MMJJ
_RS05690
+0.2
1.7
hypothetical protein
compare
MMJJ
_RS08675
+0.2
1.2
phosphate ABC transporter ATP-binding protein PstB
compare
MMJJ
_RS05510
+0.2
1.3
archaellum operon transcriptional activator EarA family protein
compare
MMJJ
_RS08305
+0.2
0.9
peroxiredoxin
compare
MMJJ
_RS00875
+0.2
1.1
hydrogenase iron-sulfur subunit
compare
MMJJ
_RS07205
+0.2
0.9
MTH895/ArsE family thioredoxin-like protein
compare
MMJJ
_RS00890
+0.2
1.2
coenzyme F420 hydrogenase subunit gamma
compare
MMJJ
_RS05350
+0.2
0.9
DUF192 domain-containing protein
compare
MMJJ
_RS06560
+0.2
1.3
site-2 protease family protein
compare
MMJJ
_RS05665
+0.2
1.2
hypothetical protein
compare
MMJJ
_RS01280
+0.2
1.4
hydroxylamine reductase
compare
MMJJ
_RS00630
+0.2
1.1
betaine/proline/choline family ABC transporter ATP-binding protein
compare
MMJJ
_RS08945
+0.2
0.8
DUF61 family protein
compare
MMJJ
_RS08445
+0.2
0.9
cell division ATPase MinD
compare
MMJJ
_RS04610
+0.2
0.9
ribosome assembly RNA-binding protein YhbY
compare
MMJJ
_RS07905
+0.2
1.0
DUF89 domain-containing protein
compare
MMJJ
_RS05965
+0.2
1.5
MFS transporter
compare
MMJJ
_RS05525
+0.2
1.1
GTP-binding protein
compare
MMJJ
_RS06790
+0.2
1.4
nucleotidyltransferase family protein
compare
MMJJ
_RS05235
+0.2
1.5
Flp pilus assembly complex ATPase component TadA
compare
MMJJ
_RS05715
+0.2
1.3
phosphoadenosine phosphosulfate reductase family protein
compare
MMJJ
_RS07760
+0.2
1.1
GNAT family N-acetyltransferase
compare
MMJJ
_RS07985
+0.2
0.9
hypothetical protein
compare
MMJJ
_RS06455
+0.2
1.2
YeeE/YedE family protein
compare
MMJJ
_RS03605
+0.2
0.9
TIGR00297 family protein
compare
MMJJ
_RS00705
+0.2
1.1
nitrogenase iron protein
compare
MMJJ
_RS06470
+0.2
1.1
tripartite tricarboxylate transporter permease
compare
MMJJ
_RS01595
+0.2
0.9
U32 family peptidase
compare
MMJJ
_RS01060
+0.2
0.8
ABC transporter ATP-binding protein
compare
MMJJ
_RS08735
+0.2
1.3
hypothetical protein
compare
MMJJ
_RS06465
+0.2
1.2
hypothetical protein
compare
MMJJ
_RS07835
+0.2
0.9
UPF0489 family protein
compare
MMJJ
_RS06055
+0.2
0.9
S-methyl-5-thioribose-1-phosphate isomerase
compare
MMJJ
_RS06080
+0.2
1.2
serine/threonine protein kinase
compare
MMJJ
_RS08210
+0.2
1.6
hypothetical protein
compare
MMJJ
_RS03940
+0.2
1.1
DMT family transporter
compare
MMJJ
_RS06520
+0.2
1.0
TldD/PmbA family protein
compare
MMJJ
_RS01505
+0.2
0.8
DUF2124 domain-containing protein
compare
MMJJ
_RS06550
+0.2
1.1
ABC transporter permease
compare
MMJJ
_RS05705
+0.2
1.3
hypothetical protein
compare
MMJJ
_RS09015
+0.2
1.1
SPFH domain-containing protein
compare
MMJJ
_RS06235
+0.2
1.2
IGHMBP2 family helicase
compare
MMJJ
_RS06430
+0.2
0.8
haloacid dehalogenase
compare
MMJJ
_RS00960
+0.2
0.9
flavodoxin family protein
compare
MMJJ
_RS05335
+0.2
1.0
heavy metal-binding domain-containing protein
compare
MMJJ
_RS01735
+0.2
1.0
rubrerythrin family protein
compare
MMJJ
_RS06400
+0.2
0.7
FumA C-terminus/TtdB family hydratase beta subunit
compare
MMJJ
_RS03850
+0.2
0.8
nucleoside-diphosphate kinase
compare
MMJJ
_RS08835
+0.2
1.1
signal peptide peptidase SppA
compare
MMJJ
_RS08360
+0.2
1.2
FprA family A-type flavoprotein
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments